Fat emulsions based on structured lipids (1,3-specific triglycerides): An investigation of the in vitro interaction with plasma proteins

Clinical Nutrition

Volumn 15, Issue 4, 1996, Pages 175-178

  Hedeman, H ^a   Luck M ^b   Blunk, T ^b,c   Frokjaer, S ^a   Muller R H ^b  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACID; INTRALIPID; LIPID; LIPID EMULSION; PLASMA PROTEIN; SOYBEAN OIL; TRIACYLGLYCEROL; VEGETABLE OIL;

ARTICLE; CHEMICAL INTERACTION; CIRCULATION; EMULSION; ESTERIFICATION; HUMAN; HUMAN CELL; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN ANALYSIS;

EID: 0029818497     PISSN: 02615614     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0261-5614(96)80237-8     Document Type: Article

References (25)

1. Hedeman H, Brøndsted H, Mullertz A, Frokjaer S. Fat emulsions based on structured lipids (1,3-specific triglycerides): an investigation of the in vivo fate. Pharm Res 1996; 13: 725-728
2. Wretlind A. Recollections of pioneers in nutrition: landmarks in the development of parenteral nutrition. J Am Coll Nutr 1992; 11: 366-373
3. Wretlind A. Parenteral nutrition. Nutr Rev 1981; 39: 257-265
4. Hallberg D, Holm I, Obel A L, Schuberth O, Wretlind A. Fat emulsions for complete intravenous nutrition. Postgrad Med J 1967; 43:307-316
5. Yamaguchi T, Mizushima Y. Lipid microspheres for drug delivery from the pharmaceutical viewpoint. Crit Rev Ther Drug Carr Syst 1994; 11: 215-229
6. Davis S S, Washington C, West P, Illum L, Liversidge G, Sternson L, Kirsh R. Lipid emulsions as drug delivery system. Ann NY Acad Sci 1987; 507: 75-88
7. Bach A C, Frey A, Lutz O. Clinical and experimental effects of medium-chain triglyceride-based fat emulsions - a review. Clin Nutr 1989; 8: 223-235
8. Sandstr̈m R, Hyltander A, Körner U, Lundholm K. Structured triglycerides to postoperative patients: a safety and tolerance study. JPEN 1993; 17: 153-157
9. Koruda M J, Rolandelli R H, Bliss D Z, Hastings J, Rombeau J L, Settle R G. Parenteral nutrition supplemented with short-chain fatty acids: effect on the small-bowel mucosa in normal rats. Am J Clin Nutr 1990; 51: 685-689
10. Carpentier Y A. Intravascular metabolism of fat emulsions: the Arvid Wretlind lecture, Espen 1988. Clin Nutr 1989; 8: 115-125
11. Carpentier Y A, Richelle M, Bihain B E, Dahlan W, Haumont D, Deckelbaum R J. Interactions between exogenous fat and plasma/lipoproteins. Infusionstherapie 1987; 14: 29-32
12. Connelly P W, Kuksis A. Effect of core composition and particle size of lipid emulsions on apolipoprotein transfer of plasma lipoproteins in vivo. BBA 1981; 666: 81-89
13. Hamosh M, Hamosh P. Lipoprotein lipase: its physiological and clinical significance. Molec Aspects Med. 1983; 6: 199-289
14. Iriyama K, Carpentier Y A. Clinical significance of transfer of apolipoproteins between triacylglycerol-rich particles in lipid emulsions and plasma lipoproteins. Nutrition 1994; 10: 252-254
15. Tenkanen H, Ehnholm C. Molecular biology of apolipoprotein A-IV. Curr Opin Lipid 1993; 4: 95-99
16. Davis S S. Emulsions systems for the delivery of drugs by the parenteral route. In: Bundgaard H, Bagger Hansen A, Kofod H (eds) Optimization of Drug Delivery. Copenhagen: Munksgaard, 1982: 333-346
17. Blunk T, Hochstrasser D F, Sanchez J-C, Müller B W, Müller R H. Colloidal carriers for intravenous drug targeting: plasma protein adsorption patterns on surface-modified latex particles evaluated by two-dimensional polyacrylamide gel electrophoresis. Electrophoresis 1993; 14: 1382-1387
18. Blunk T. Plasmaproteinadsorption auf kolloidalen Arzneistoffträgern. PhD thesis, University of Kiel, 1994
19. Hochstrasser D F, Harrington M G, Hochstrasser A-C, Miller M J, Merril C R. Methods for increasing the resolution of two-dimensional protein electrophoresis. Anal Biochem 1988; 173: 424-435
20. Appel R D, Hochstrasser D F, Funk M, Vargas J R, Pellegrini C, Muller A F, Scherrer J R. The MELANIE project: from a biopsy to automatic protein map interpretation by computer. Electrophoresis 1991; 12: 722-735
21. Golaz O, Hughes G J, Frutiger S et al. Plasma and red blood cell protein maps: update 1993. Electrophoresis 1993; 14: 1223-1231
22. Anderson N L, Anderson N G. A two-dimensional gel database of human plasma proteins. Electrophoresis 1991; 12: 883-906
23. Brouwer C B, de Bruin T W A, Jansen H, Erkelens D W. Different clearance of intravenously administered olive oil and soybean-oil emulsions: role of hepatic lipase. Am J Clin Nutr 1993; 57: 533-539
24. Robinson S F, Quarfordt S H. Apoproteins in association with Intralipid incubations in rat and human plasma. Lipids 1979; 14: 343-349
25. Driscoll D F, Bhargava H N, Li L, Zaim R H, Babayan V K, Bistrian B R. Physico chemical stability of total nutrient admixtures. Am J Health Syst Pharm 1995; 52: 623-634