Physical and biological characteristics of the antitumor drug actinomycin D analogues derivatized at N-methyl-L-valine residues

Biochemistry

Volumn 35, Issue 40, 1996, Pages 13240-13249

  Takusagawa, Fusao ^a   Wen, Li ^a   Chu, Wenhua ^a   Li, Qifang ^a   Takusagawa, Ken T ^a   Carlson, Robert G ^a   Weaver, Robert F ^a  

^a UNIVERSITY OF KANSAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; DACTINOMYCIN; VALINE;

ABSORPTION SPECTROSCOPY; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CHEMICAL MODIFICATION; CHROMATOPHORE; CRYSTAL STRUCTURE; DNA BINDING; ENZYME MODIFICATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; RESIDUE ANALYSIS; RNA SYNTHESIS;

ANTIBIOTICS, ANTINEOPLASTIC; BINDING SITES; DACTINOMYCIN; DNA; DNA-DIRECTED RNA POLYMERASES; DRUG DESIGN; HELA CELLS; HUMANS; MODELS, MOLECULAR; NUCLEIC ACID DENATURATION; NUCLEIC ACID SYNTHESIS INHIBITORS; OLIGODEOXYRIBONUCLEOTIDES; SOLUBILITY; SPECTROPHOTOMETRY; TEMPERATURE; TRANSCRIPTION, GENETIC; VALINE;

EID: 0029818364     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi960828r     Document Type: Article

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