Effects of S20749, a close analogues of sumatriptan, on porcine carotid haemodynamics and human isolated coronary artery

Pharmacology and Toxicology

Volumn 79, Issue 4, 1996, Pages 199-204

  Saxena, Pramod R ^a   MaassenVanDenBrink, Antoinette ^a   Heiligers, Jan P C ^a   Scalbert, Elizabeth ^b   Lemaître, B Guardiola ^b  

^a ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

^b INSTITUT DE RECHERCHES INTERNATIONALES SERVIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMIGRAINE AGENT; S 20749; SUMATRIPTAN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTERY CONSTRICTION; ARTICLE; CAPILLARY FLOW; CAROTID ARTERY FLOW; CONTROLLED STUDY; CORONARY ARTERY; EXPERIMENTAL MODEL; HEMODYNAMICS; HUMAN; HUMAN TISSUE; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; SWINE;

ANIMALIA; SUIDAE; SUS SCROFA;

EID: 0029817198     PISSN: 09019928     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0773.1996.tb02088.x     Document Type: Article

References (16)

1. Bax, W. A., G. J. Renzenbrink, D. Van Heuven-Nolsen, E. J. M. Thijssen, E. Bos & P. R. Saxena: 5-HT receptors mediating contractions of the isolated human coronary artery. Eur. J. Pharmacol. 1993, 239, 203-210.
2. 2 receptor activation. Eur. J. Pharmacol. 1989, 161, 91-94.
3. 1-like receptors. Brit. J. Pharmacol. 1991a, 104, 183-189.
4. 1-like receptors in the reduction of porcine cranial arteriovenous anastomotic shunting by sumatriptan. Brit. J. Pharmacol. 1991b, 102, 323-330.
5. Den Boer, M. O., L. J. Van Woerkens, J. A. E. Somers, D. J. Duncker, B. Lachmann, P. R. Saxena & P. D. Verdouw: On the preservation and regulation of vascular tone in arteriovenous anastomoses during anesthesia. J. Appl. Physiol. 1993, 75, 782-789.
6. 1D receptor antagonist. Brit. J. Pharmacol. 1996, 118, 85-92.
7. Feniuk, W., P. P. A. Humphrey & M. J. Perren: The selective carotid arterial vasoconstrictor action of GR43175 in anaesthetized dogs. Brit. J. Pharmacol. 1989, 96, 83-90.
8. Heyck, H.: Pathogenesis of migraine. Res. Clin. Stud. Headache 1969, 2, 1-28.
9. Humphrey, P. P. A., E. Apperley, W. Feniuk & M. J. Perren: A rational approach to identifying a fundamentally new drug for the treatment of migraine. In: Cardiovascular pharmacology of 5-hydroxytryptamine: Prospective therapeutic applications. Ed.: P. R. Saxena, D. I. Wallis, W. Wouters & P. Bevan. Kluwer academic publishers, Dordrecht, 1990, pp. 416-431.
10. Saxena, P. R.: Cranial arteriovenous shunting: an in vivo animal model for migraine. In: Experimental headache models in animal and man. Eds.: J. Olesen & M.A. Moskowitz. Lippincott-Raven Publishers, Philadelphia, 1995, pp. 189-198.
11. Saxena, P. R. & M. D. Ferrari: From serotonin receptor classification to the antimigraine drug sumatriptan. Cephalalgia 1992, 12, 187-196.
12. 1D receptor agonists. Exp. Opin. Invest. Drugs 1996, 5, in press.
13. Saxena, P. R. & P. Tfelt-Hansen: Sumatriptan. In: The headaches. Eds.: J. Olesen, P. Tfelt-Hansen & K. M. A. Welch. Raven Press Ltd., New York, 1993, pp. 329-341.
14. Saxena, P. R. & P. D. Verdouw: Redistribution by 5-HT of carotid arterial blood at the expense of arteriovenous blood flow. J. Physsiol. (London) 1982, 332, 501-520.
15. Saxena, P. R. & C. M. Villalón: Cardiovascular effects of serotonin agonists and antagonists. J. Cardiovasc. Pharmacol. 1990, 15 (Suppl. 7), S17-S34.
16. Saxena, P. R., H. C. Schamhardt, R. P. Forsyth & J. Loeve: Computer programs for the radioactive microsphere technique. Determination of regional blood flows and other haemodynamic variables in different experimental circumstances. Comp. Progr. Biomed. 1980, 12, 63-84.