An interstitial 11q23 deletion proven to be a rearrangement interrupting the MLL gene in an infant with acute myeloblastic leukemia

Leukemia

Volumn 10, Issue 11, 1996, Pages 1844-1846

  Leblanc, T ^a   Le Coniat, M ^b   Flexor, M ^b   Baruchel, A ^a   Daniel, M T ^c   Berger, R ^b  

^a SAINT LOUIS HOSPITAL   (France)

^b CNRS   (France)

^c Laboratoire Central d'Hematologie   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE MYELOBLASTIC LEUKEMIA; CASE REPORT; CENTROMERE; CHROMOSOME 11Q; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE DELETION; GENE REARRANGEMENT; HUMAN; INFANT; KARYOTYPE; MARKER CHROMOSOME; NOTE; PRIORITY JOURNAL; SOUTHERN BLOTTING;

EID: 0029817194     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Note

References (7)

1. Pui C-H, Ribeiro RC, Campana D, Raimondi SC, Hancock ML, Behm FG, Sandlund JT, Rivera GK, Evans WE, Crist WM, Krance R. Prognostic factors in the acute lymphoid and myeloid leukemias in infants. Leukemia 1996; 10: 952-956.
2. Michel G, Leverger G, Leblanc T, Nelken B, Baruchel A, Landman-Parker J, Thuret I, Bergeron C, Bordigoni P, Esperou-Bourdeau H, Perel Y, Vannier J-P, Schaison G. Allogenic bone marrow transplantation vs aggressive post-remission chemotherapy for children with acute myeloid leukemia in first remission. A prospective study from the French Society of Pediatric Hematology and Immunology (SHIP). Bone Marrow Transplant 1996; 17: 191-196.
3. Van Heyningen V, Gaudray G, Gerhard D. Report of the committee on the genetic constitution of chromosome 11. In: Cuticchia AJ (ed). Human Gene Mapping 1994: A Compendium. Johns Hopkins University Press: Baltimore, 1995, pp 486-530.
4. Mattéi MG, Mattéi J-F, Vidal I, Giraud F. Expression in lymphocyte and fibroblast culture of the fragile X syndrome: a new technical approach. Hum Genet 1981; 59: 166-169.
5. Rubnitz JE, Behm FG, Downing JR. 11q23 rearrangements in acute leukemia. Leukemia 1996; 10: 74-82.
6. Bernard O, Berger R. Molecular basis of 11q23 rearrangements in hematopoietic malignant proliferations. Genes Chromosom Cancer 1995; 13: 78-85.
7. Pedeutour F, Suijkerbuijk RF, Forus A, Van Gaal J, Van der Klundert W, Coindre J-M, Nicolo G, Collin F, Van Haelst U, Huffermann K, Turc-Carel C. Complex composition and co-amplification of SAS and MDM2 in ring and giant rod marker chromosomes in well-differentiated liposarcoma. Genes Chromosom Cancer 1994; 10: 85-94.