Site-specific regulation of organic osmolytes along the rat nephron

American Journal of Physiology

Volumn 271, Issue 3 PART 2, 1996, Pages

  Schmolke, Michael ^a   Bornemann, Angela ^a   Guder, Walter G ^a  

^a KLINIKUM BOGENHAUSEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BETAINE; FUROSEMIDE; GLYCEROPHOSPHORYLCHOLINE; INOSITOL; LITHIUM; SORBITOL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APICAL MEMBRANE; ARTICLE; BASOLATERAL MEMBRANE; BLADDER; DIURESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; KIDNEY; KIDNEY MEDULLA; KIDNEY TUBULE; MALE; NEPHRON; NONHUMAN; OSMOREGULATION; PRIORITY JOURNAL; RAT;

ANIMALS; DIURETICS; DRINKING; FUROSEMIDE; INOSITOL; LITHIUM; MALE; NEPHRONS; OSMOLAR CONCENTRATION; RATS; RATS, SPRAGUE-DAWLEY; SORBITOL; URINE; WATER-ELECTROLYTE BALANCE;

EID: 0029817176     PISSN: 00029513     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajprenal.1996.271.3.f645     Document Type: Article

References (34)

1. Abramow, M., and E. Cogan. Role of lithium-ADH interaction in lithium-induced polyuria. Adv. Nephrol. 13: 29-34, 1984.
2. Bagnasco, S. M., H. R. Murphy, J. J. Bedford, and M. B. Burg. Osmoregulation by slow changes in aldose reductase and rapid changes in sorbitol flux. Am. J. Physiol. 254 (Cell Physiol. 23): C788-C792, 1988.
3. Beck, F.-X., A. Dörge, R. Rick, and K. Thurau. Osmoregulation of renal papillary cells. Pfluegers Arch. 405: S28-S32, 1985.
4. Beck, F.-X., M. Schmolke, W. G. Guder, A. Dörge, and K. Thurau. Osmolytes in renal medulla during rapid changes in papillary tonicity. Am. J. Physiol. 262 (Renal Fluid Electrolyte Physiol. 31): F849-F856, 1992.
5. Beck, F.-X., M. Sone, A. Dörge, and K. Thurau. Effect of loop diuretics on organic osmolytes and cell electrolytes in the renal outer medulla. Kidney Int. 42: 843-850, 1992.
6. Christensen, S., E. Kusano, A. N. K. Yusufi, N. Murayama, and T. P. Dousa. Pathogenesis of nephrogenic diabetes insipidus due to chronic administration of lithium in rats. J. Clin. Invest. 75: 1869-1879, 1985.
7. Cogan, E., M. Svoboda, and M. Abramow. Mechanisms of lithium-vasopressin interaction in rabbit cortical collecting tubule. Am. J. Physiol. 252 (Renal Fluid Electrolyte Physiol. 21): F1080-F1087, 1987.
8. Cohen, M. A. H., K. A. Hruska, and W. H. Daughaday. Free mvo-inositol in canine kidneys: selective concentration in the renal medulla. Proc. Soc. Exp. Biol. Med. 169: 380-385, 1982.
9. Cowley, Jr., B. D., J. D. Ferraris, D. Carper, and M. B. Burg. In vivo osmoregulation of aldose reductase mRNA, protein, and sorbitol in renal medulla. Am. J. Physiol. 258 (Renal Fluid Electrolyte Physiol. 27): F154-F161, 1990.
10. Grunewald, R. W., and R. K. H. Kinne. Intracellular sorbitol content in isolated rat inner medullary collecting duct cells. Pfluegers Arch. 414: 178-184, 1989.
11. Gullans, S. R., C. W. Heilig, M. E. Stromski, and J. D. Blumenfeld. Methylamines and polyols in kidney, urinary bladder, urine, liver, brain, and plasma. Renal Physiol. Biochem. 12: 191-201, 1989.
12. Jackson, B. A., R. M. Edwards, and T. P. Dousa. Lithiuminduced polyuria: effect of lithium on adenylate cyclase and adenosine 3', 5'-monophosphate phosphodiesterase in medullary ascending limb of Henle's loop and in medullary collecting tubules. Endocrinology 107: 1693-1698, 1980.
13. Lee, K. H., S. B. Lee, and K. C. Cho. Levels of organic osmolytes in normal and diuretic rat kidneys . In: Cellular and Molecular Biology of the Kidney Contributions to Nephrology, edited by H. Koide, H. Endou, and K. Kurokawa. Basel: Karger, 1991, p. 279-283.
14. Martinez-Maldonado, M., and S. Opava-Stitzer. Distal nephron function of the rat during lithium chloride infusion. Kidney Int. 12: 17-22, 1977.
15. Moriyama, T., A. Garcia-Perez, and M. B. Burg. Factors affecting the ratio of different organic osmolytes in renal medullary cells. Am. J. Physiol. 259 (Renal Fluid Electrolyte Physiol. 28): F847-F858, 1990.
16. Nakanishi, T., and M. B. Burg. Osmoregulation of glycerophosphorylcholine content of mammalian cells. Am. J. Physiol. 257 (Cell Physiol. 26): C795-C801, 1989.
17. Nakanishi, T., and M. B. Burg. Osmoregulatory fluxes of myo-inositol and betaine in renal cells. Am J. Physiol. 257 (Cell Physiol. 26): C964-C970, 1989.
18. Nakanishi, T., R. J. Turner, and M. B. Burg. Osmoregulation of betaine transport in mammalian renal medullary cells. Am. J. Physiol. 258 (Renal Fluid Electrolyte Physiol. 27): F1061-F1067, 1990.
19. Nakanishi, T., O. Uyama, H. Nakahama, Y. Takamitsu, and M. Sugita. Determinants of relative amounts of medullary organic osmolytes: effects of NaCl and urea differ. Am. J. Physiol. 264 (Renal Fluid Electrolyte Physiol. 33): F472-F479, 1993.
20. Schmolke, M., F.-X. Beck, and W. G. Guder. Effect of antidiuretic hormone on renal organic osmolytes in Brattleboro rats. Am. J. Physiol. 257 (Renal Fluid Electrolyte Physiol. 26): F732-F737, 1989.
21. Schmolke, M., A. Bornemann, and W. G. Guder. Polyol determination along the rat nephron. Biol. Chem. Hoppe-Seyler 371: 909-916, 1990.
22. Schmolke, M., and W. G. Guder. Metabolic regulation of organic osmolytes in tubules from rat renal inner and outer medulla. Renal Physiol. Biochem. 12: 347-358, 1989.
23. Schmolke, M., E. Schleicher, and W. G. Guder. Renal sorbitol, myo-inositol and glycerophosphorylcholine in streptozotocin diabetic rats. Ear. J. Clin. Chem. Clin. Biochem. 30: 607-614, 1992.
24. Sizeland, P. C. B., S. T. Chambers, M. Levers, L. M. Bason, and R. A. Robson. Organic osmolytes in human and other mammalian kidneys. Kidney Int. 43: 448-453, 1993.
25. Strange, K., and P. S. Jackson. Swelling-activated organic osmolyte efflux: a new role for anion channels. Kidney Int. 48: 994-1003, 1995
26. Veis, J. H., B. A. Molitoris, I. Teitelbaum, J. A. Mansour, and T. Berl. Myo-inositol uptake by rat cultured inner medullary collecting tubule cells: effect of osmolality. Am. J. Physiol. 260 (Renal Fluid Electrolyte Physiol. 29): F619-F625, 1991.
27. Wirthensohn, G., S. Lefrank, M. Schmolke, and W. G. Guder. Regulation of organic osmolyte concentrations in tubules from rat inner medulla. Am. J. Physiol. 256 (Renal Fluid Electrolyte Physiol. 25): F128-F135, 1989.
28. Wolff, S. D., T. S. Stanton, S. L. James, and R. S. Balaban. Acute regulation of the predominant organic solutes of the rabbit renal inner medulla. Am. J. Physiol. 257 (Renal Fluid Electrolyte Physiol. 26): F676-F681, 1989.
29. Yamaki, M., E. Kusano, T. Tetsuka, S. Takeda, S. Homma, N. Murayama, and Y. Asano. Celluar mechanism of lithiuminduced nephrogenic diabetes insipidus in rats. Am. J. Physiol. 261 (Renal Fluid Electrolyte Physiol. 30): F505-F511, 1991.
30. Yamauchi, A., H. M. Kwon, S. Uchida, A. S. Preston, and J. S. Handler. Myo-inositol and betaine transporters regulated by tonicity are basolateral in MDCK cells. Am. J. Physiol. 261 (Renal Fluid Electrolyte Physiol. 30): F197-F202, 1991.
31. +/myo-inositol cotransporter in rat kidney. J. Clin. Invest. 96: 1195-1201, 1995.
32. Yancey, P. H. Osmotic effectors in kidneys of xeric and mesic rodents: corticomedullary distributions and changes with water availability. J. Comp. Physiol. B 158: 369-380, 1988.
33. Yancey, P. H., and M. B. Burg. Distribution of major organic osmolytes in rabbit kidneys in diuresis and antidiuresis. Am. J. Physiol. 257 (Renal Fluid Electrolyte Physiol. 26): F602-F607, 1989.
34. Yancey, P. H., and G. N. Somero. Counteraction of urea destabilization of protein structure by methylamine osmoregulatory compounds of elasmobranch fishes. Biochem. J. 183: 317-323, 1979.