Enhanced renal sensitivity to angiotensin actions in diabetes mellitus in the rat

American Journal of Physiology

Volumn 271, Issue 3 PART 2, 1996, Pages

  Kennefick, Thomas M ^a,b   Oyama, Terry T ^a   Thompson, Michele M ^a   Vora, Jiten P ^a   Anderson, Sharon ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b Division of Nephrology   (United States)

Author keywords

Glomerular filtration rate; Hemodynamics; Renin

Indexed keywords

ANGIOTENSIN; ANGIOTENSIN I;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DIABETIC NEPHROPATHY; GLOMERULUS FILTRATION RATE; KIDNEY BLOOD FLOW; KIDNEY PLASMA FLOW; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PRIORITY JOURNAL; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM;

ANGIOTENSIN I; ANGIOTENSIN II; ANIMALS; BLOOD PRESSURE; DIABETES MELLITUS, EXPERIMENTAL; GLOMERULAR FILTRATION RATE; INJECTIONS, INTRA-ARTERIAL; INJECTIONS, INTRAVENOUS; KIDNEY; MALE; RATS; RATS, INBRED STRAINS; RENAL CIRCULATION;

EID: 0029817174     PISSN: 00029513     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajprenal.1996.271.3.f595     Document Type: Article

References (29)

1. Anderson, S., F. F. Jung, and J. R. Ingelfinger. Renal renin-angiotensin system in diabetes: functional, immunohistochemical, and molecular biological correlations. Am. J. Physiol. 265 (Renal Fluid Electrolyte Physiol. 34): F477-F486, 1993.
2. Anderson, S., H. G. Rennke, and B. M. Brenner. Nifedipine versus fosinopril in uninephrectomized diabetic rats. Kidney Int. 41: 891-897, 1992.
3. Anderson, S., H. G. Rennke, D. L. Garcia, and B. M. Brenner. Short and long term effects of antihypertensive therapy in the diabetic rat. Kidney Int. 36: 526-536, 1989.
4. Bank, N., M. A. G. Lahorra, H. S. Aynedjian, and D. Schlondorf. Vasoregulatory hormones and the hyperfiltration of diabetes. Am. J. Physiol. 254 (Renal Fluid Electrolyte Physiol. 23): F202-F209, 1988.
5. Bjorck, S. The renin angiotensin system in diabetes mellitus: a physiological and therapeutic study. Scand. J. Urol. Nephrol. Suppl. 126, 1990.
6. Cassis, L. A. Downregulation of the renin-angiotensin system in streptozotocin-diabetic rats. Am. J. Physiol. 262 (Endocrinol. Metab. 25): E105-E109, 1992.
7. Craven, P. A., M. F. Melheim, and F. R. DeRubertis. Thromboxane in the pathogenesis of glomerular injury in diabetes. Kidney Int. 42: 937-946, 1992.
8. Fox, J., S. Guan, A. A. Hymel, and L. G. Navar. Dietary Na and ACE inhibition effects on renal tissue angiotensin I and and ACE activity in rats. Am. J. Physiol. 262 (Renal Fluid Electrolyte Physiol. 31): F902-F909, 1992.
9. Garlick, R. L., J. S. Mazer, P. J. Higgins, and H. F. Bunn. Characterization of glycated hemoglobins. Relevance to monitoring of diabetic control and analysis of other proteins. J. Clin. Invest. 71: 1062-1072, 1983.
10. Haak, T., E. Jungman, A. Felber, U. Hillman, and K. H. Usadel. Increased levels of endothelin in diabetic patients with hypertension. Am. J. Hypertens. 5: 161-166, 1992.
11. Hostetter, T. H., H. G. Rennke, and B. M. Brenner. The case for intrarenal hypertension in the initiation and progression of diabetic and other glomerulopathies. Am. J. Med. 72: 375-380, 1982.
12. Hostetter, T. H., J. L. Troy, and B. M. Brenner. Glomerular hemodynamics in experimental diabetes mellitus. Kidney Int. 19: 410-415, 1981.
13. Ingelfinger, J. R., R. E. Pratt, K. Ellison, and V. J. Dzau. Sodium regulation of the angiotensinogen mRNA expression in rat kidney cortex and medulla. J. Clin. Invest. 78: 1311-1315, 1986.
14. Kalinyak, J. E., L. A. Sechi, C. A. Griffin, B. R. Don, K. Tavangar, F. B. Kreamer, A. R. Hoffman, and M. Schambelan. The renin-angiotensin system in streptozotocin-induced diabetes mellitus in the rat. J. Am. Soc. Nephrol. 4: 1337-1345, 1993.
15. Kriz, W. Aperiarterial pathway for the intrarenal distribution of renin. Kidney Int. 31, Suppl. 20: S51-S56, 1987.
16. Lewis, E. J., L. G. Hunsicker, R. P. Bain, and R. D. Rohde. The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy. N. Engl. J. Med. 329: 1456-1462, 1993.
17. 1 receptor blockade on glomerular hemodynamics: involvement of the renin-angiotensin system. Am. J. Physiol. 267 (Renal Fluid Electrolyte Physiol. 36): F783-F790, 1994.
18. Navar, L. G., L. Lewis, A. Hymel, B. Braam, and K. D. Mitchell. Tubular fluid concentrations and kidney contents of angiotensin I and angiotensin in anesthetized rats. J. Am. Soc. Nephrol. 5: 1153-1158, 1994.
19. Navar, L. G., L. Rosivall, P. K. Carmines, and S. Oparil. Effects of locally formed angiotensin on renal hemodynamics. Federation Proc. 45: 1448-1453, 1986.
20. Okwueze, M. 1., A. A. Hymel, and R. C. Vari. Systemic and intrarenal angiotensin profiles during the onset of IDDM and glomerular hyperfiltration in BBIDP rats (Abstract). J. Am. Soc. Nephrol. 4: 800, 1993.
21. Reams, G., D. Villarreal, J. H. Bauer. Intrarenal metabolism of angiotensin II. Am. J. Physiol. 258 (Renal Fluid Electrolyte Physiol. 27): F1510-F1515, 1990.
22. Rosivall, L., A. J. Narkates, S. Oparil, and L. G. Navar. De novo intrarenal formation of angiotensin during control and enhanced renin secretion. Am. J. Physiol. 252 (Renal Fluid Electrolyte PhysM. 21): F1118-F1123, 1987.
23. Seikaly, M. G., B. S. Arant, Jr., and F. D. Seney, Endogenous angiotensin concentrations in specific intrarenal fluid compartments of the rat. J. Clin. Invest. 86: 1352-1357, 1990.
24. Vallon, V., L. M. Wead, and R. C. Blantz. Renal hemodynamics and plasma and kidney angiotensin in established diabetes mellitus in rats: effect of sodium and salt restriction. J. Am. Soc. Nephrol. 5: 1761-1767, 1995.
25. Vernace, M. A., L. Herbert, P. F. Mento, M. E. Maita, and B. M. Wilkes. Increased metabolic clearance rate of angiotensin
26. in diabetic rats: role of the kidneys (Abstract). J. Am. Soc. Nephrol. 5: 974, 1994.
27. Wilkes, B. M., P. F. Mento, and M. A. Vernace. Angiotensin responsiveness in hyperfiltering and nonhyperfiltering diabetic rats. J. Am. Soc. Nephrol. 4: 1346-1353, 1993.
28. Zatz, R., B. R. Dunn, T. W. Meyer, S. Anderson, H. G. Rennke, and B. M. Brenner. Prevention of diabetic glomerulopathy by pharmacological amelioration of glomerular capillary hypertension. J. Clin. Invest. 77: 1925-1930, 1986.
29. Zatz, R., T. W. Meyer, H. G. Rennke, and B. M. Brenner. Predominance of hemodynamic rather than metabolic factors in the pathogenesis of diabetic glomerulopathy. Proc. Natl. Acad. Sci. USA 82: 5963-5967, 1985.