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Volumn 83, Issue 10, 1996, Pages 809-815

Cytotoxicity of tamoxifen and its major metabolites in breast cancer cell lines;Cytotoxicite du tamoxifene et de ses principaux metabolites sur lignees cellulaires d'adenocarcinomes mammaires humains

Author keywords

in vitro; metabolites; resistance; tamoxifen

Indexed keywords

4 HYDROXYTAMOXIFEN; DRUG METABOLITE; ESTRADIOL; ESTROGEN RECEPTOR; NORTAMOXIFEN; PROGESTERONE RECEPTOR; TAMOXIFEN;

EID: 0029816840     PISSN: 00074551     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (6)

References (20)
  • 2
    • 0025367297 scopus 로고
    • Genetic and immunochemichal analysis of mutant p53 in human breast cancer cell lines
    • Bartek J, Iggo R, Gannon J, Lane DP. Genetic and immunochemichal analysis of mutant p53 in human breast cancer cell lines. Oncogene 1990;5:893-9
    • (1990) Oncogene , vol.5 , pp. 893-899
    • Bartek, J.1    Iggo, R.2    Gannon, J.3    Lane, D.P.4
  • 3
    • 2542464918 scopus 로고
    • Phenol red in tissue culture media is a weak estrogen: Implication concerning the study of estrogen-responsive cells in culture
    • Berthois Y, Katzenellenbogen JA, Katzenellenbogen BS. Phenol red in tissue culture media is a weak estrogen: implication concerning the study of estrogen-responsive cells in culture. Proc Natl Acad Sci USA 1986;83:2496-500
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 2496-2500
    • Berthois, Y.1    Katzenellenbogen, J.A.2    Katzenellenbogen, B.S.3
  • 4
    • 0026436497 scopus 로고
    • Meta-analyse des traitements medicaux adjuvants dans les cancers du sein. Resultats à10 ans
    • Bonneterre J. Meta-analyse des traitements medicaux adjuvants dans les cancers du sein. Resultats à10 ans. Bull Cancer 1992;79:459-64
    • (1992) Bull Cancer , vol.79 , pp. 459-464
    • Bonneterre, J.1
  • 5
    • 0028010863 scopus 로고
    • Contribution àl'élucidation du mécanisme d'action antiŒstrogènique et antitumoral du tamoxifène
    • Borgna JL. Contribution àl'élucidation du mécanisme d'action antiŒstrogènique et antitumoral du tamoxifène. Bull Cancer 1994;81:29-37
    • (1994) Bull Cancer , vol.81 , pp. 29-37
    • Borgna, J.L.1
  • 6
    • 0025696935 scopus 로고
    • Tamoxifen and 17ß-estradiol reduce the human fluidity of human breast cancer cells
    • Clarke R, Van den Berg HW, Murphy RF. Tamoxifen and 17ß-estradiol reduce the human fluidity of human breast cancer cells. J Natl Cancer Inst 1990;82:1702-5
    • (1990) J Natl Cancer Inst , vol.82 , pp. 1702-1705
    • Clarke, R.1    Van Den Berg, H.W.2    Murphy, R.F.3
  • 7
    • 0025821012 scopus 로고
    • Activity of tamoxifen and its metabolites on endocrine-dependent and endocrine-independent breast cancer cells
    • Coradini D, Cappelletti V, Granata G, Di Fronzo G. Activity of tamoxifen and its metabolites on endocrine-dependent and endocrine-independent breast cancer cells. Tumor Biol 1991;12:149-58
    • (1991) Tumor Biol , vol.12 , pp. 149-158
    • Coradini, D.1    Cappelletti, V.2    Granata, G.3    Di Fronzo, G.4
  • 8
    • 0028795855 scopus 로고
    • Exon 5 deletion variant estrogen receptor messenger RNA expression in relation to tamoxifen resistance and progesterone receptor/pS2 status in human breast cancer
    • Daffada AAI, Johnston SRD, Smith IE, Detre S, King N, Dowsett M. Exon 5 deletion variant estrogen receptor messenger RNA expression in relation to tamoxifen resistance and progesterone receptor/pS2 status in human breast cancer. Cancer Res 1995;55:288-93
    • (1995) Cancer Res , vol.55 , pp. 288-293
    • Daffada, A.A.I.1    Johnston, S.R.D.2    Smith, I.E.3    Detre, S.4    King, N.5    Dowsett, M.6
  • 9
    • 0027464805 scopus 로고
    • Identification of residues in the estrogen receptor that confer differential sensitivity to estrogen and hydroxytamoxifen
    • Danielian PS, White R, Hoare SA, Fawell SE, Parker MG. Identification of residues in the estrogen receptor that confer differential sensitivity to estrogen and hydroxytamoxifen. Mol Endocrinol 1993;7:232-40
    • (1993) Mol Endocrinol , vol.7 , pp. 232-240
    • Danielian, P.S.1    White, R.2    Hoare, S.A.3    Fawell, S.E.4    Parker, M.G.5
  • 10
    • 0018079661 scopus 로고
    • Establishment and characterization of three new continuous cell lines derived from human breast carcinomas
    • Engel LW, Young NA, Tralka TS, Lippman ME, O'Brien SJ, Joyce MJ. Establishment and characterization of three new continuous cell lines derived from human breast carcinomas. Cancer Res 1978;38:3352-64
    • (1978) Cancer Res , vol.38 , pp. 3352-3364
    • Engel, L.W.1    Young, N.A.2    Tralka, T.S.3    Lippman, M.E.4    O'Brien, S.J.5    Joyce, M.J.6
  • 11
    • 0024506261 scopus 로고
    • A randomized clinical trial evaluating tamoxifen in the treatment of patients with node-negative breast cancer who have estrogen receptor-positive tumors
    • Fisher B, Costantino J, Redmond C, et al. A randomized clinical trial evaluating tamoxifen in the treatment of patients with node-negative breast cancer who have estrogen receptor-positive tumors. N Engl J Med 1989;320:479-84
    • (1989) N Engl J Med , vol.320 , pp. 479-484
    • Fisher, B.1    Costantino, J.2    Redmond, C.3
  • 12
    • 0021618186 scopus 로고
    • The pharmacology and clinical uses of tamoxifen
    • Furr BJA, Jordan VC. The pharmacology and clinical uses of tamoxifen. Pharmacol Ther 1984;25:127-205.
    • (1984) Pharmacol Ther , vol.25 , pp. 127-205
    • Furr, B.J.A.1    Jordan, V.C.2
  • 13
    • 0023760993 scopus 로고
    • Development of tamoxifen-stimulated growth of MCF-7 tumors in athymic mice after long-term antiestrogen administration
    • Gottardis MM, Jordan VC. Development of tamoxifen-stimulated growth of MCF-7 tumors in athymic mice after long-term antiestrogen administration. Cancer Res 1988; 48:5183-7
    • (1988) Cancer Res , vol.48 , pp. 5183-5187
    • Gottardis, M.M.1    Jordan, V.C.2
  • 14
    • 0023129529 scopus 로고
    • Calcium channel antagonist properties of the antineoplastic antiestrogen tamoxifen in the PC-12 neurosecretory cell line
    • Greenberg DA, Carpenter CL, Messing RO. Calcium channel antagonist properties of the antineoplastic antiestrogen tamoxifen in the PC-12 neurosecretory cell line. Cancer Res 1987;47:70-4
    • (1987) Cancer Res , vol.47 , pp. 70-74
    • Greenberg, D.A.1    Carpenter, C.L.2    Messing, R.O.3
  • 15
    • 0020701032 scopus 로고
    • Multiple estrogen receptor assays in human breast cancer
    • Hull DF, Clark GM, Osborne CK. Multiple estrogen receptor assays in human breast cancer. Cancer Res 1983;43: 413-9
    • (1983) Cancer Res , vol.43 , pp. 413-419
    • Hull, D.F.1    Clark, G.M.2    Osborne, C.K.3
  • 16
    • 0027240643 scopus 로고
    • A model to describe how a point mutation of the estrogen receptor alters the structure-function relationship of antiestrogens
    • Jiang SY, Parker CJ, Jordan VC. A model to describe how a point mutation of the estrogen receptor alters the structure-function relationship of antiestrogens. Breast Cancer Res Treat 1993;26:139-47
    • (1993) Breast Cancer Res Treat , vol.26 , pp. 139-147
    • Jiang, S.Y.1    Parker, C.J.2    Jordan, V.C.3
  • 17
    • 0025872863 scopus 로고
    • Identification of the cytochrome p450 IIIA family as the enzymes involved in the N-demethylation of tamoxifen in human liver microsomes
    • Jacolot F, Simon I, Dreano Y, Beaune P, Riche C, Berthou F. Identification of the cytochrome p450 IIIA family as the enzymes involved in the N-demethylation of tamoxifen in human liver microsomes. Biochem Pharmacol 1991;41: 1911-9
    • (1991) Biochem Pharmacol , vol.41 , pp. 1911-1919
    • Jacolot, F.1    Simon, I.2    Dreano, Y.3    Beaune, P.4    Riche, C.5    Berthou, F.6
  • 18
    • 0020691322 scopus 로고
    • Determination and pharmacology of a new hydroxylated metabolite of tamoxifen observed in patient sera during therapy for advanced breast cancer
    • Jordan VC, Bain RR, Brown RR, Gordon B, Santos MA. Determination and pharmacology of a new hydroxylated metabolite of tamoxifen observed in patient sera during therapy for advanced breast cancer. Cancer Res 1983;43: 1446-50
    • (1983) Cancer Res , vol.43 , pp. 1446-1450
    • Jordan, V.C.1    Bain, R.R.2    Brown, R.R.3    Gordon, B.4    Santos, M.A.5
  • 19
    • 0024202461 scopus 로고
    • Hormone receptors assays: Clinical usefulness in the management of the carcinoma of the breast
    • Jordan VC, Wolf MF, Mirecki DM. Hormone receptors assays: Clinical usefulness in the management of the carcinoma of the breast. Crit Rev Clin Lab Sci 1988;26:97-152
    • (1988) Crit Rev Clin Lab Sci , vol.26 , pp. 97-152
    • Jordan, V.C.1    Wolf, M.F.2    Mirecki, D.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.