Residue Trp-48 of Tva is critical for viral entry but not for high- affinity binding to the SU glycoprotein of subgroup A avian leukosis and sarcoma viruses

Journal of Virology

Volumn 70, Issue 11, 1996, Pages 7510-7516

  Zingler, Kurt ^a   Young, John A T ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESIN; ASPARTIC ACID; CYSTEINE; HYBRID PROTEIN; MUTANT PROTEIN; RECEPTOR PROTEIN; VIRUS ENVELOPE PROTEIN; VIRUS GLYCOPROTEIN;

AMINO ACID SUBSTITUTION; ARTICLE; AVIAN LEUKOSIS ONCOVIRUS; BINDING AFFINITY; CONTROLLED STUDY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; RETROVIRUS INFECTION; VIRUS INFECTIVITY;

EID: 0029816826     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.70.11.7510-7516.1996     Document Type: Article

References (55)

1. Albritton, L. M., J. W. Kim, L. Tseng, and J. M. Cunningham. 1993. Envelope-binding domain in the cationic amino acid transporter determines the host range of ecotropic murine retroviruses. J. Virol. 67:2091-2096.
2. Arthos, J., K. C. Deen, M. A. Chaikin, J. A. Fornwald, G. Sathe, Q. J. Sattentau, P. R. Clapham, R. A. Weiss, J. S. McDougal, C. Pietropaolo, R. Axel, A. Truneh, P. J. Maddon, and R. W. Sweet. 1989. Identification of the residues in human CD4 critical for the binding of HIV. Cell 57:469-481.
3. Ashkenazi, A., L. G. Presta, S. A. Marsters, T. R. Camerato, K. A. Rosenthal, B. M. Fendly, and D. J. Capon. 1990. Mapping the CD4 binding site for human immunodeficiency virus by alanine-scanning mutagenesis. Proc. Natl. Acad. Sci. USA 87:7150-7154.
4. Ban, J., D. Portetelle, C. Altaner, B. Horion, D. Milan, V. Krchnak, A. Burny, and R. Kettmann. 1993. Isolation and characterization of a 2.3-kilobase-pair cDNA fragment encoding the binding domain of the bovine leukemia virus cell receptor. J. Virol. 67:1050-1057.
5. Bates, P., J. A. T. Young, and H. E. Varmus. 1993. A receptor for subgroup A Rous sarcoma virus is related to the low density lipoprotein receptor. Cell 74:1043-1051.
6. Bélanger, C., K. Zingler, and J. A. T. Young. 1995. Importance of cysteines in the LDLR-related domain of the subgroup A avian leukosis and sarcoma virus receptor for viral entry. J. Virol. 69:1019-1024.
7. Bowman, M. R., K. D. MacFerrin, S. L. Schreiber, and S. J. Burakoff. 1990. Identification and structural analysis of residues in the V1 region of CD4 involved in interaction with human immunodeficiency virus envelope glycoprotein gp120 and class II major histocompatibility complex molecules. Proc. Natl. Acad. Sci. USA 87:9052-9056.
8. Brand, D., K. Srinivasan, and J. Sodroski. 1995. Determinants of human immunodeficiency virus type 1 entry in the CDR2 loop of the CD4 glycoprotein. J. Virol. 69:166-171.
9. Brodsky, M. H., M. Warton, R. M. Myers, and D. R. Littman. 1990. Analysis of the site in CD4 that binds to the HIV envelope glycoprotein. J. Immurol. 144:3078-3086.
10. Bullough, P. A., F. M. Hughson, J. J. Skehel, and D. C. Wiley. 1994. Structure of influenza haemagglutinin at the pH of membrane fusion. Nature (London) 371:37-43.
11. Capon, D. J., S. M. Chamow, J. Mordenti, S. A. Marsters, T. Gregory, H. Mitsuya, R. A. Byrn, C. Lucas, F. M. Wurm, J. E. Groopman, S. Broder, and D. H. Smith. 1989. Designing CD4 immunoadhesins for AIDS therapy. Nature (London) 337:525-531.
12. Carr, C. M., and P. S. Kim. 1993. A spring-loaded mechanism for the conformational change of influenza hemagglutinin. Cell 73:823-832.
13. Clayton, L. K., R. E. Hussey, R. Steinbrich, H. Ramachandran, Y. Husain, and E. L. Reinherz. 1988. Substitution of murine for human CD4 residues identifies amino acids critical for HIV-gp120 binding. Nature (London) 335:363-366.
14. Connolly, L., K. Zingler, and J. A. T. Young. 1994. A soluble form of a receptor for subgroup A avian leukosis and sarcoma viruses (ALSV-A) blocks infection and hinds directly to ALSV-A. J. Virol. 68:2760-2764.
15. Daly, N. L., J. T. Djordejevic, P. A. Kroon, and R. Smith. 1995. Three-dimensional structure of the second cysteine-rich repeat from the human low density lipoprotein receptor. Biochemistry 34:14474-14481.
16. Daly, N. L., M. J. Scanlon, J. T. Djordjevic, P. A. Kroon, and R. Smith. 1995. Three-dimensional structure of a cysteinc-rich repeat from the low-density lipoprotein receptor. Proc. Natl. Acad. Sci. USA 92:6334-6338.
17. Eiden, M. V., K. B. Farrell, and C. A. Wilson. 1996. Substitution of a single amino acid residue is sufficient to allow the human ampbotropic murine leukemia virus receptor to also function as a gibbon ape leukemia virus receptor. J. Virol. 70:1080-1085.
18. Einfeld, D., and E. Hunter. 1988. Oligomeric structure of a prototype retrovirus glycoprotein. Proc. Natl. Acad. Sci. USA 85:8688-8692.
19. Einfeld, D. A., and E. Hunter. 1994. Expression of the TM protein of Rous sarcoma virus in the absence of SU shows that this domain is capable of oligomerization and intracellular transport. J. Virol. 68:2513-2520.
20. Fountoulakis, M., C. Mesa, G. Schmid, R. Gentz, M. Manneberg, M. Zulauf, Z. Dembic, and G. Garotta. 1995. Interferon gamma receptor extracellular domain expressed as IgG fusion protein in Chinese hamster ovary cells. Purification, biochemical characterization, and stoichiometry of binding. J. Biol. Chem. 270:3958-3964.
21. Gilbert, J. M., P. Bates, H. E. Varmus, and J. M. White. 1994. The receptor for the subgroup A avian leukosis-sarcoma viruses binds to subgroup A hut not to subgroup C envelope glycoprotein. J. Virol. 68:5623-5628.
22. Gilbert, J. M., L. D. Hernandez, J. W. Balliel, P. Bates, and J. M. White. 1995. Receptor-induced conformational changes in the subgroup A avian leukosis and sarcoma virus envelope glycoprotein. J. Virol. 69:7410-7415.
23. Gilbert, J. M., D. Mason, and J. M. White. 1990. Fusion of Rous sarcoma virus with host cells does not require exposure to low pH. J. Virol. 64:5106-5113.
24. Haak-Frendscho, M., S. A. Marsters, S. M. Chamow, D. H. Peers, N. J. Simpson, and A. Ashkenazi. 1993. Inhibition of interferon-gamma by an interferon-gamma receptor immunoadhesin. Immunology 79:594-599.
25. Harlow, E., and D. Lane. 1988. Antibodies: a laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor. N.Y.
26. Hunter, E., and R. Swanstrom. 1990. Retrovirus envelope glycoproteins. Curr. Top. Microbiol. Immunol. 157:187-253.
27. Kozak, S. L., D. C. Siess, M. P. Kavanaugh, A. D. Miller, and D. Kabat. 1995. The envelope glycoprotein of an amphotropic murine retrovirus binds specifically to the cellular receptor/phosphate transporter of susceptible species. J. Virol. 69:3433-3440.
28. Landau, N. R., M. Warton, and D. R. Littman. 1988. The envelope glycoprotein of the human immunodeficiency virus binds to the immunoglobulin-like domain of CD4. Nature (London) 334:159-162.
29. Maddon, P. J., A. G. Dalgleish, J. S. McDougal, P. R. Clapham, R. A. Weiss, and R. Axel. 1986. The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain. Cell 47:333-348.
30. Malhotra, S., A. G. Scott, T. Zavorotinskaya, and L. M. Albritton. 1996. Analysis of the murine ecotropic leukemia virus receptor reveals a common biochemical determinant on diverse cell surface receptors that is essential to retrovirus entry. J. Virol. 70:321-326.
31. Martin, S., J. M. Casasnovas, D. E. Staunton, and T. A. Springer. 1993. Efficient neutralization and disruption of rhinovirus by chimeric ICAM-1/ immunoglobulin molecules. J. Virol. 47:3561-3568.
32. McClure, M. O., M. A. Sommerfelt, M. Marsh, and R. A. Weiss. 1990. The pH independence of mammalian retrovirus infection. J. Gen. Virol. 71:767-773.
33. McDougal, J. S., M. S. Kennedy, J. M. Sligh, S. P. Cort, A. Mawle, and J. K. A. Nicholson. 1986. Binding of HTLV-III/LAV to T4+ cells by a complex of the 110K viral protein and the T4 molecule. Science 231:382-385.
34. Miller, D. G., and A. D. Miller. 1994. A family of retroviruses that utilize related phosphate transports for cells entry. J. Virol. 68:8270-8276.
35. Mizukami, T., T. R. Fuerst, E. A. Berger, and B. Moss. 1988. Binding region for human immunodeficiency virus (HIV) and epitopes for HIV-blocking monoclonal antibodies of the CD4 molecule defined by site-directed mutagenesis. Proc. Natl. Acad. Sci. USA 85:9273-9277.
36. Moebius, U., L. K. Clayton, S. Abraham, S. C. Harrison, and E. L. Reinherz. 1992. The human immunodeficiency virus gp120 binding site on CD4: delineation by quantitative equilibrium and kinetic binding studies of mutants in conjunction with a high-resolution CD4 atomic structure. J. Exp. Med. 176:507-517.
37. Pedersen, L., S. V. Johann, M. van Zeijl, F. S. Pedersen, and B. O'Hara. 1995. Chimeras of receptors for gibbon ape leukemia virus/feline leukemia virus B and amphotropic murine leukemia virus reveal different modes of receptor recognition by retrovirus. J. Virol. 69:2401-2405.
38. Peterson, A., and B. Seed. 1988. Genetic analysis of monoclonal antibody and HIV binding sites on the human lymphocyte antigen CD4. Cell 54:65-72.
39. Pitti, R. M., S. A. Marsters, M. Haak-Frendscho, G. C. Osaka, J. Mordenti, S. M. Chamow, and A. Ashkenazi. 1994. Molecular and biological properties of an interleukin-1 receptor immunoadhesin. Mol. Immunol. 31:1345-1351.
40. Rong, L., and P. Bates. 1995. Analysis of the subgroup A avian sarcoma and leukosis virus receptor: the 40-residue, cysteine-rich, low-density lipoprotein receptor repeat motif of Tva is sufficient to mediate viral entry. J. Virol. 69:4847-4853.
41. Ryu, S.-E., P. D. Kwong, A. Truneh, T. G. Porter, J. Arthos, M. Rosenberg, X. Dai, N.-H. Xuong, R. Axel, R. W. Sweet, and W. A. Hendrickson. 1990. Crystal structure of an HIV-binding recombinant fragment of human CD4. Nature (London) 348:419-426.
42. Sattentau, Q. J., J. P. Moore, F. Vignaux, F. Traincard, and P. Poignard. 1993. Conformational changes induced in the envelope glycoproteins of the human and simian immunodeficiency viruses by soluble receptor binding. J. Virol. 67:7383-7393.
43. Simon, J. H. M., C. Somoza, G. A. Schockmel, M. Collin, S. J. Davis, A. F. Williams, and W. James. 1993. A rat CD4 mutant containing the gp120-binding site mediates human immunodeficiency virus type 1 infection. J. Exp. Med. 177:949-954.
44. Stein, B. S., S. D. Gowda, J. D. Lifson, R. C. Penhallow, K. G. Bensch, and E. G. Engleman. 1987. pH-independent HIV entry into CD4-positive T cells via virus envelope fusion to the plasma membrane. Cell 49:659-668.
45. Suda, T., T. Takahashi, P. Golstein, and S. Nagata. 1993. Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family. Cell 75:1169-1178.
46. Tailor, C. S., Y. Takeuchi, B. O'Hara, S. V. Johann, R. A. Weiss, and M. K. L. Collins. 1993. Mutation of amino acids within the gibbon ape leukemia virus (GALV) receptor differentially affects feline leukemia virus subgroup B, simian sarcoma-associated virus, and GALV infections. J. Virol. 67:6737-6741.
47. Tyers, M., G. Tokiwa, R. Nash, and B. Futcher. 1992. The Cln3-Cdc28 kinase complex of S. cerevisiae is regulated by proteolysis and phosphorylation. EMBO J. 11:1773-1784.
48. Wang, H., R. Paul, R. E. Burgeson, D. R. Keene, and D. Kabat. 1991. Plasma membrane receptors for ecotropic murine retroviruses require a limiting accessory factor. J. Virol. 65:6468-6477.
49. Wang, J., Y. Yan, T. P. J. Garrett, J. Liu, D. W. Rodgers, R. L. Garlick, G. E. Tarr, Y. Husain, E. L. Reinherz, and S. C. Harrison. 1990. Atomic structure of a fragment of human CD4 containing two immunoglobulin-like domains. Nature (London) 348:411-418.
50. Weiss, R. A. 1993. Cellular receptors and viral glycoproteins involved in retrovirus entry, p. 1-107. In J. A. Levy (ed.), The Retroviridae, vol. 2. Plenum Press, New York.
51. White, J. M. 1992. Membrane fusion. Science 258:917-924.
52. Wigler, M., S. Silverstein, L. S. Lee, A. Pellicer, Y. C. Cheng, and R. Axel. 1977. Transfer of purified herpes virus thymidine kinase gene to cultured mouse cells. Cell 11:223-232.
53. Yoshimoto, T., E. Yoshimoto, and D. Meruelo. 1993. Identification of amino acid residues critical for infection with ecotropic murine leukemia retrovirus. J. Virol. 67:1310-1314.
54. Yu, H., N. Soong, and W. F. Anderson. 1995. Binding kinetics of ecotropic (Moloney) murine leukemia retrovirus with NIH 3T3 cells. J. Virol. 69:6557-6562.
55. Zingler, K., C. Bélanger, R. Peters, D. Agard, and J. A. T. Young. 1995. Identification and characterization of the viral interaction determinant of the subgroup A avian leukosis virus receptor. J. Virol. 69:4261-4266.