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Volumn 89, Issue 3, 1996, Pages 309-315

Genetic stability of gene targeted immunoglobulin loci. I. Heavy chain isotype exchange induced by a universal gene replacement vector

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN G1; IMMUNOGLOBULIN HEAVY CHAIN;

EID: 0029816793     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2567.1996.d01-752.x     Document Type: Article
Times cited : (5)

References (22)
  • 1
    • 0343459960 scopus 로고
    • Homologous recombination in hybridoma cells: Heavy chain chimeric antibody produced by gene targeting
    • FELL H.P., YARNOLD S., HELSTRÖM I., HELLSTRÖM K.E. & FOLGER K.R. (1989) Homologous recombination in hybridoma cells: heavy chain chimeric antibody produced by gene targeting. Proc Natl Acad Sci USA 86, 8507.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 8507
    • Fell, H.P.1    Yarnold, S.2    Helström, I.3    Hellström, K.E.4    Folger, K.R.5
  • 2
    • 0028931373 scopus 로고
    • Unaltered immunoglobulin expression in hybridoma cells modified by targeting of the heavy chain locus with an integration vector
    • MOCIKAT R., KARDINAL C., LANG P. ZEIDLER R. & THIERFELDER S. (1995) Unaltered immunoglobulin expression in hybridoma cells modified by targeting of the heavy chain locus with an integration vector. Immunology 84, 159.
    • (1995) Immunology , vol.84 , pp. 159
    • Mocikat, R.1    Kardinal, C.2    Lang, P.3    Zeidler, R.4    Thierfelder, S.5
  • 3
    • 0028012101 scopus 로고
    • Chimerization of antitumor antibodies via homologous recombination conversion vectors
    • YARNOLD S. & FELL H.P. (1994) Chimerization of antitumor antibodies via homologous recombination conversion vectors. Cancer Res 54, 506.
    • (1994) Cancer Res , vol.54 , pp. 506
    • Yarnold, S.1    Fell, H.P.2
  • 4
    • 0025868460 scopus 로고
    • An internal ribosome binding site can be used to select for homologous recombinants at an immunoglobulin heavy-chain locus
    • WOOD C.R., MORRIS G.E., ALDERMAN E.M., FOUSER L. & KAUFMAN R.J. (1991) An internal ribosome binding site can be used to select for homologous recombinants at an immunoglobulin heavy-chain locus. Proc Natl Acad Sci USA 88, 8006.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 8006
    • Wood, C.R.1    Morris, G.E.2    Alderman, E.M.3    Fouser, L.4    Kaufman, R.J.5
  • 5
    • 0028345960 scopus 로고
    • Production of mouse V/human C chimeric κ genes by homologous recombination in hybridoma cells
    • SUN W., XIONG J. & SHULMAN M.J. (1994) Production of mouse V/human C chimeric κ genes by homologous recombination in hybridoma cells. J Immunol 152, 695.
    • (1994) J Immunol , vol.152 , pp. 695
    • Sun, W.1    Xiong, J.2    Shulman, M.J.3
  • 6
    • 0023741405 scopus 로고
    • Homologous recombination can restore normal immunoglobulin production in a mutant hybridoma cell line
    • BAKER M.D., PENNELL N., BOSNOYAN L. & SHULMAN M.J. (1988) Homologous recombination can restore normal immunoglobulin production in a mutant hybridoma cell line. Proc Natl Acad Sci USA 85, 6432.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 6432
    • Baker, M.D.1    Pennell, N.2    Bosnoyan, L.3    Shulman, M.J.4
  • 7
    • 0025073480 scopus 로고
    • Homologous recombination in hybridoma cells: Dependence on time and fragment length
    • SHULMAN M.J., NISSEN L. & COLLINS C. (1990) Homologous recombination in hybridoma cells: dependence on time and fragment length. Mol Cell Biol 10, 4466.
    • (1990) Mol Cell Biol , vol.10 , pp. 4466
    • Shulman, M.J.1    Nissen, L.2    Collins, C.3
  • 8
    • 0028069735 scopus 로고
    • Restoration of a normal level of immunoglobulin production in a hybridoma cell line following modification of the chromosomal immunoglobulin μ gene by gene replacement
    • BAKER M.D., KARN H.A. & READ L.R. (1994) Restoration of a normal level of immunoglobulin production in a hybridoma cell line following modification of the chromosomal immunoglobulin μ gene by gene replacement. J Immunol Methods 168, 25.
    • (1994) J Immunol Methods , vol.168 , pp. 25
    • Baker, M.D.1    Karn, H.A.2    Read, L.R.3
  • 9
    • 0023646810 scopus 로고
    • Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells
    • THOMAS K.R. & CAPECCHI M.R. (1987) Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells. Cell 51, 503.
    • (1987) Cell , vol.51 , pp. 503
    • Thomas, K.R.1    Capecchi, M.R.2
  • 10
    • 0027532257 scopus 로고
    • Location of crossovers during gene targeting with insertion and replacement vectors
    • DENG C., THOMAS K.R. & CAPECCHI M.R. (1993) Location of crossovers during gene targeting with insertion and replacement vectors. Mol Cell Biol 13, 2134.
    • (1993) Mol Cell Biol , vol.13 , pp. 2134
    • Deng, C.1    Thomas, K.R.2    Capecchi, M.R.3
  • 11
    • 0026636660 scopus 로고
    • The role and fate of DNA ends for homologous recombination in embryonic stem cells
    • HASTY P., RIVERA-PÉREZ J. & BRADLEY A. (1992) The role and fate of DNA ends for homologous recombination in embryonic stem cells. Mol Cell Biol 12, 2464.
    • (1992) Mol Cell Biol , vol.12 , pp. 2464
    • Hasty, P.1    Rivera-Pérez, J.2    Bradley, A.3
  • 12
    • 0025773393 scopus 로고
    • Double-strand break repair in a mammalian gene targeting reaction
    • VALANCIUS V. & SMITHIES O. (1991) Double-strand break repair in a mammalian gene targeting reaction. Mol Cell Biol 11, 4389.
    • (1991) Mol Cell Biol , vol.11 , pp. 4389
    • Valancius, V.1    Smithies, O.2
  • 14
    • 0024388160 scopus 로고
    • High-frequency homologous recombination between duplicate chromosomal immunoglobulin μ heavy-chain constant regions
    • BAKER M.D. (1989) High-frequency homologous recombination between duplicate chromosomal immunoglobulin μ heavy-chain constant regions. Mol Cell Biol 9, 5500.
    • (1989) Mol Cell Biol , vol.9 , pp. 5500
    • Baker, M.D.1
  • 15
    • 0028969797 scopus 로고
    • Integration vectors for antibody chimerization by homologous recombination in hybridoma cells
    • KARDINAL C., HOOIJBERG E., LANG P., ZEIDLER R. & MOCIKAT R. (1995) Integration vectors for antibody chimerization by homologous recombination in hybridoma cells. Eur J Immunol 25, 792.
    • (1995) Eur J Immunol , vol.25 , pp. 792
    • Kardinal, C.1    Hooijberg, E.2    Lang, P.3    Zeidler, R.4    Mocikat, R.5
  • 16
    • 0028180086 scopus 로고
    • Replacement-like recombination induced by an integration vector with a murine homology flank at the immunoglobulin heavy-chain locus in mouse and rat hybridoma cells
    • LANG P. & MOCIKAT R. (1994) Replacement-like recombination induced by an integration vector with a murine homology flank at the immunoglobulin heavy-chain locus in mouse and rat hybridoma cells. Mol Gen Genet 242, 528.
    • (1994) Mol Gen Genet , vol.242 , pp. 528
    • Lang, P.1    Mocikat, R.2
  • 17
    • 0024515966 scopus 로고
    • Neutralization of immunosuppression by antibodies against variable as well as constant regions of monoclonal anti-Thy-1 xenoantibodies and their ability to be suppressed by initial T cell depletion
    • KREMMER E., THIERFELDER S., KUMMER U., LEDERER R. & MYSLIWIETZ J. (1989) Neutralization of immunosuppression by antibodies against variable as well as constant regions of monoclonal anti-Thy-1 xenoantibodies and their ability to be suppressed by initial T cell depletion. Transplantation 47, 641.
    • (1989) Transplantation , vol.47 , pp. 641
    • Kremmer, E.1    Thierfelder, S.2    Kummer, U.3    Lederer, R.4    Mysliwietz, J.5
  • 18
    • 0014752565 scopus 로고
    • Synthesis, assembly and secretion of gamma globulin by mouse myeloma cells. I. Adaptation of the Merwin plasma cell tumor-11 to culture, cloning, and characterization of gamma globulin subunits
    • LASKOV R. & SCHARFF M.D. (1970) Synthesis, assembly and secretion of gamma globulin by mouse myeloma cells. I. Adaptation of the Merwin plasma cell tumor-11 to culture, cloning, and characterization of gamma globulin subunits. J Exp Med 131, 515.
    • (1970) J Exp Med , vol.131 , pp. 515
    • Laskov, R.1    Scharff, M.D.2
  • 19
    • 0023181650 scopus 로고
    • Rapid isolation of eukaryotic DNA
    • BOWTELL D. (1987) Rapid isolation of eukaryotic DNA. Anal Biochem 162, 463.
    • (1987) Anal Biochem , vol.162 , pp. 463
    • Bowtell, D.1
  • 20
    • 0025895425 scopus 로고
    • Target frequency and integration pattern for insertion and replacement vectors in embryonic stem cells
    • HASTY P., RIVERA-PÉREZ J., CHANG C. & BRADLEY A. (1991) Target frequency and integration pattern for insertion and replacement vectors in embryonic stem cells. Mol Cell Biol 11, 4509.
    • (1991) Mol Cell Biol , vol.11 , pp. 4509
    • Hasty, P.1    Rivera-Pérez, J.2    Chang, C.3    Bradley, A.4
  • 21
    • 0026770668 scopus 로고
    • High-fidelity gene targeting in embryonic stem cells by using sequence replacement vectors
    • THOMAS K.R., DENG C. & CAPECCHI M.R. (1992) High-fidelity gene targeting in embryonic stem cells by using sequence replacement vectors. Mol Cell Biol 12, 2919.
    • (1992) Mol Cell Biol , vol.12 , pp. 2919
    • Thomas, K.R.1    Deng, C.2    Capecchi, M.R.3
  • 22
    • 0026753186 scopus 로고
    • Reexamination of gene targeting frequency as a function of the extent of homology between the targeting vector and the target locus
    • DENG C. & CAPECCHI M.R. (1992) Reexamination of gene targeting frequency as a function of the extent of homology between the targeting vector and the target locus. Mol Cell Biol 12, 3365.
    • (1992) Mol Cell Biol , vol.12 , pp. 3365
    • Deng, C.1    Capecchi, M.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.