Effect of methylcellulose on the stability of oil-in-water emulsions

International Journal of Pharmaceutics

Volumn 140, Issue 1, 1996, Pages 97-109

  Gullapalli, Rampurna P ^a   Sheth, Bhogi B ^b  

^a RP Scherer North America   (United States)

^b Nashville Clinical Education Center and Statewide   (United States)

Author keywords

Auxiliary emulsifiers; Emulsions; Interactions; Methylcellulose; Stability

Indexed keywords

METHYL PARABEN; METHYLCELLULOSE; MICROCRYSTALLINE CELLULOSE; POLYMER; POLYSORBATE 20; RITODRINE; SORBITAN LAURATE; WATER OIL CREAM;

ARTICLE; COMPLEX FORMATION; EMULSION; FLOCCULATION; MOLECULAR STABILITY; PARTICLE SIZE; PRIORITY JOURNAL; VISCOSITY;

EID: 0029816481     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-5173(96)04591-7     Document Type: Article

References (16)

1. Atlas HLB System, A Time-saving Guide to Emulsifier Selection, 3rd Edn, Atlas Chemical Industries Inc., Wilmington, Delaware, 1963, pp. 7-13.
2. Becher, P., In Emulsions: Theory and Practice, 2nd Edn, Reinhold Co., New York, 1965, pp. 267-325.
3. Bergenstahl, B., Gums as stabilizers for emulsifier covered emulsion droplets. In Phillips, G.O., Wedlock, D.J. and Williams, P.A. (Eds.), Gums and Stabilizers for the Food Industry, Vol. 4, IRL Press, Washington D.C., 1988, pp. 363-369.
4. Bohm, J.T.C. and Lyklema, J., The adsorption behavior of polyelectrolytes at liquid-liquid interfaces and the properties of polyelectrolyte-stabilized emulsions. In Smith, A.L. (Eds.), Theory and Practice of Emulsion Technology, Academic Press, New York, 1976, pp. 23-39.
5. Dickenson, E. and Galazka, V.B., Bridging flocculation induced by competitive adsorption: Implications for emulsion stability. J. Chem. Soc. Faraday Trans., 87 (1991) 963-969.
6. Friberg, S.E., Goldsmith, L.B. and Hilton, M.L., Theory of emulsions. In Lieberman H.A., Reiger, M.M. and Banker, G.S. (Eds.), Pharmaceutical Dosage Forms: Disperse Systems, Vol. 1, Marcel Dekker, New York, 1988, pp. 56-60.
7. Lankveld, J.M.G. and Lyklema, J., Adsorption of Polyvinyl Alcohol on the paraffin-water interface. I. Interfacial tension as a function of time and concentration. J. Colloid Interface Sci., 41 (1972) 454-465.
8. Lashmar, U.T. and Beesley, J., Correlation of rheological properties of an oil in water emulsion with manufacturing procedures and stability. Int. J. Pharm., 91 (1993) 59-67.
9. Niebergall, P.J., Schnaare, R.L. and Sugita, E.T., Nonlinear regression applied to non-Newtonian flow. J. Pharm. Sci., 60 (1971) 1393-1402.
10. Oza, K.P. and Frank, F.G., Microcrystalline cellulose stabilized emulsions. J. Disp. Sci. Tech., 7 (1986) 543-561.
11. Reichman, D. and Garti, N., Interaction of galactomannans with ethoxylated sorbitan esters-surface tension and viscosity effects. In Phillips, G.O., Wedlock, D.J. and Williams, P.A. (Eds.), Gums and Stabilizers for the Food Industry, Vol. 4, IRL Press, Washington D.C., 1988, pp. 441-446.
12. Reiger, M.M., Emulsions. In Lachman, L., Lieberman, H.A. and Kanig, J.L. (Eds.), Theory and Practice of Industrial Pharmacy, 3rd Edn, Lea and Febiger, Philadelphia, 1986, pp. 518-519.
13. Shinoda, K., Saito, H and Arai, H., The effect of the size and the distribution of the oxyethylene chain lengths of non-ionic emulsifiers on the stability of emulsions. J. Colloid Interface Sci., 35 (1971) 624-630.
14. Storz, G.K., DeKay, H.G. and Banker, G.S., Investigation of cellulosic polymer-polyhydroxyl polymer interacted polyelectrolyte system II. J. Pharm. Sci., 54 (1965) 85-91.
15. Tadros, T.F., Stability of oil-in-water emulsions in polymer-surfactant complexes. Paraffin-water emulsions in mixtures of Poly (Vinyl Alcohol) with cetyltrimethyl ammonium bromide or sodium dodecylbenzene sulfonate. In Smith, A.L. (Eds.), Theory and Practice of Emulsion Technology, Academic Press, New York, 1976, pp. 281-299.
16. Zatz, J.L. and Ip, B.K., Stabilization of oil-in-water emulsions by gums. J. Soc. Cosmet. Chem., 37 (1986) 329-350.