Oral absorption of trimethoprim-sulfamethoxazole in patients with AIDS

Pharmacotherapy

Volumn 16, Issue 4, 1996, Pages 656-662

  Klepser, Michael E ^a   Zhu, Zhu ^a   Nicolau, David P ^a   Banevicius, Mary Anne ^a   Belliveau, Paul P ^a   Ross, Jack W ^a   Broisman, Larry ^a   Quintiliani, Richard ^a   Nightingale, Charles H ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

COTRIMOXAZOLE;

ADULT; AIDS RELATED COMPLEX; ANTIBIOTIC PROPHYLAXIS; AREA UNDER THE CURVE; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG EFFICACY; DRUG FORMULATION; DRUG HALF LIFE; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFECTION PREVENTION; INTRAVENOUS DRUG ADMINISTRATION; MALE; ORAL DRUG ADMINISTRATION; PNEUMOCYSTIS PNEUMONIA; RANDOMIZED CONTROLLED TRIAL;

ACQUIRED IMMUNODEFICIENCY SYNDROME; ADMINISTRATION, ORAL; ADULT; ANTI-INFECTIVE AGENTS; BIOLOGICAL AVAILABILITY; CROSS-OVER STUDIES; FEMALE; HUMANS; INJECTIONS, INTRAVENOUS; MALE; PNEUMONIA, PNEUMOCYSTIS; TRIMETHOPRIM-SULFAMETHOXAZOLE COMBINATION;

EID: 0029816259     PISSN: 02770008     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Greenson KJ, Belitsos PC, Yardley JH, Bartlett JG. AIDS enteropathy: occult enteric infections and duodenal mucosal alterations in chronic diarrhea. Ann Intern Med 1991;114: 366-72.
2. Kotler DP, Gaetz HP, Lange M, Klein EB, Holt PR. Enteropathy associated with the acquired immunodeficiency syndrome. Ann Intern Med 1984;101:421-8.
3. Ulrich R, Zeitz M, Heise W, L'age M, Höffken G, Riecken EO. Small intestinal structure and function in patients infected with human immunodeficiency virus (HIV): evidence for HIV-induced enteropathy. Ann Intern Med 1989;111:15-21.
4. Heise C, Danderkar S, Kumar P, Duplantier R, Donovan RM, Halsted CH. Human immunodeficiency virus infection of enterocytes and mononuclear cells in human jejunal mucosa. Gastroenterology 1991;100:1521-7.
5. Laughon BE, Druckman DA, Vernon A, et al. Prevalence of enteric pathogens in homosexual men with and without acquired immunodeficiency syndrome. Gastroenterology 1988;94:984-93.
6. Frances ND, Boylston AW, Roberts AH, Parkin JM, Pinching AJ. Cytomegalovirus infection in gastrointestinal tracts of patients infected with HIV-1 or AIDS. J Clin Pathol 1989;42:1055-64.
7. Jacobson MA, Mills J. Serious cytomegalovirus disease in acquired immunodeficiency syndrome (AIDS). Clinical findings, diagnosis, and treatment. Ann Intern Med 1988;108:585-94.
8. Soave R, Danner RL, Honig CL, et al. Cryptosporidiosis in homosexual men. Ann Intern Med 1984;110:504-11.
9. Soave R, Johnson WD Jr. Cryptosporidium and Isospora belli infections. J Infect Dis 1988;157:225-9.
10. Ma P, Kaufman D, Montana J. Isospora belli diarrheal infection in homosexual men. AIDS Res 1984;1:327-38.
11. Desportes I, Le Charpentier Y, Galian A, et al. Occurrence of a new microsporidian. Enterocytozoon bieneusi n.g., n.sp., in the enterocytes of a human patient with AIDS. J Protozool 1985;32:250-4.
12. Gray JR, Rabeneck L. Atypical mycobacterial infection of the gastrointestinal tract in AIDS patients. Am J Gastroenterol 1989;84:1521-4.
13. Dworkin B, Wormser GP, Rosenthal WS, et al. Gastrointestinal manifestations of the acquired immunodeficiency syndrome: a review of 22 cases. Am J Gastroenterol 1985;10: 774-8.
14. Smith PD, Quinn TC, Strober W, Janoff EN, Masur H. Gastrointestinal infections in AIDS. Ann Intern Med 1992;116:63-77.
15. Gillin JS, Shike M, Alcock N, et al. Malabsorption and mucosal abnormalities of the small intestine in the acquired immunodeficiency syndrome. Ann Intern Med 1985;102: 619-22.
16. Chin TWF, Vandenbroucke A, Fong IW. Pharmacokinetics of trimethoprim-sulfamethoxazole in critically ill and non-critically ill AIDS patients. Antimicrob Agents Chemother 1995;39:28-33.
17. Siber GR, Gorham CC, Ericson JF, Smith AL. Pharmacokinetics of intravenous trimethoprim-sulfamethoxazole in children and adults with normal and impaired renal function. Rev Infect Dis 1982;4:566-78.
18. Gatti G, Flaherty J, Bupp J, White J, Borin M, Gambertoglio JG. Comparative study of bioavailabilities and pharmacokinetics of clindamycin in healthy volunteers and patients with AIDS. Antimicrob Agents Chemother 1993;37:1137-43.
19. DeMuria D, Forrest A, Rich J, Scavone JM, Cohen LG, Kazanjian PH. Pharmacokinetics and bioavailability of fluconazole in patients with AIDS. Antimicrob Agents Chemother 1993;37:2187-92.
20. Patel KB, Belmonte R, Crowe HM. Drug malabsorption and resistant tuberculosis in HIV-infected patients. N Engl J Med 1995;332:336-7.
21. Stevens RC, Laizure SC, Sanders PL, Stein DS. Multiple-dose pharmacokinetics of 12 milligrams of trimethoprim and 60 milligrams of sulfamethoxazole per kilogram of body weight per day in healthy volunteers. Antimicrob Agents Chemother 1993;37:448-52.