Marked symptom reduction in two women with bulimia nervosa treated with the testosterone receptor antagonist flutamide

Acta Psychiatrica Scandinavica

Volumn 94, Issue 2, 1996, Pages 137-139

  Bergman, L ^a   Eriksson, E ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Antitestosterone; Bulimia; Flutamide; Testosterone

Indexed keywords

FLUTAMIDE; TESTOSTERONE;

ADULT; ARTICLE; BULIMIA; CASE REPORT; CLINICAL TRIAL; FEMALE; HUMAN; PRIORITY JOURNAL;

EID: 0029815419     PISSN: 0001690X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0447.1996.tb09838.x     Document Type: Article

References (10)

1. BAISCHER W, KOINIG G, HARTMANN B, HUBER J, LANGER G. Hypothalamic-pituitary-gonadal axis in depressed women - elevated blood testosterone concentrations compared to normal controls. Psychoneuroendocrinology 1995: 20: 553-559.
2. ERIKSSON E, SUNDBLAD C, LISJÖ P, MODIGH K, ANDERSCH B. Serum levels of androgens are higher in women with premenstrual irritability and dysphoria than in controls. Psychoneuroendocrinology 1992: 17: 195-204.
3. SHULMAN LH, DEROGATIS L, SPIELVOGEL R, MILLER JL, ROSE LI. Serum androgens and depression in women with facial hirsutism. J Am Acad Dermatol 1992: 27: 178-181.
4. CASAS M, ALVAREZ E, DURO P et al. Antiandrogenic treatment of obsessive-compulsive neurosis. Acta Psychiatr Scand 1986: 73: 221-222.
5. PETERSON BS, LECKMAN JF, SCAHILL L et al. Steroid hormones and Tourette's syndrome: early experience with antiandrogen therapy. J Clin Psychopharmacol 1984: 14: 131-135.
6. American Psychiatric Association. Diagnostic and statistical manual of mental disorders, revised 3rd edn. Washington, DC: American Psychiatric Association Press, 1987.
7. GLADIS MM, WALSH BT. Premenstrual exacerbation of binge eating in bulimia. Am J Psychiatry 1987: 144: 1592-1595.
8. SUNDBLAD C, BERGMAN L, ERIKSSON E. High levels of free testosterone in women with bulimia nervosa. Acta Psychiatr Scand 1994: 90: 397.
9. COUZINET B, PHOLSENA M, YOUNG J, SCHAISON G. The impact of a pure anti-androgen (flutamide) on LH, FSH, androgens and clinical status in idiopathic hirsutism. Clin Endocrinol 1993: 39: 157-162.
10. MAZURE CM, HALMI KA, SUNDAY SR, ROMANO SJ, EINHORN AM. The Yale-Brown-Cornell Eating Disorder Scale: development, use, reliability and validity. J Psychiatr Res 1994: 28: 425-445.