Differential glycosylation, virion incorporation, and sensitivity to neutralizing antibodies of human immunodeficiency virus type 1 envelope produced from infected primary T-lymphocyte and macrophage cultures

Journal of Virology

Volumn 70, Issue 9, 1996, Pages 6431-6436

  Willey, Ronald L ^a   Shibata, Riri ^a   Freed, Eric O ^a   Cho, Michael W ^a   Martin, Malcolm A ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NEUTRALIZING ANTIBODY; VIRUS ENVELOPE PROTEIN;

ANTIGENICITY; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; MACROPHAGE; PRIORITY JOURNAL; PROTEIN GLYCOSYLATION; T LYMPHOCYTE; VIRUS ENVELOPE; VIRUS NEUTRALIZATION;

EID: 0029815226     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.70.9.6431-6436.1996     Document Type: Article

References (54)

1. Allan, J. S., J. E. Colligan, F. Barin, M. F. McLane, J. G. Sodroski, C. A. Rosen, W. A. Haseltine, T. H. Lee, and M. Essex. 1985. Major glycoprotein antigens that induce antibodies in AIDS patients are encoded by HTLV-III. Science 228:1091-1094.
2. Anderson, K., A. M. Q. King, R. A. Lerch, and G. W. Wertz. 1992. Polylactosaminoglycan modification of the respiratory syncytial virus small hydrophobic (SH) protein: a conserved feature among human and bovine respiratory syncytial viruses. Virology 191:417-430.
3. Arthur, L. O., J. W. Bess, R. C. Sowder, R. E. Benveniste, D. L. Mann, J. C. Chermann, and L. E. Henderson. 1992. Cellular proteins bound to immunodeficiency viruses: implications for pathogenesis and vaccines. Science 258:1935-1938.
4. Back, N. K. T., L. Smit, J. J. De Long, W. Keulen, M. Schutten, J. Goudsmit, and M. Tersmette. 1994. An N-glycan within the human immunodeficiency virus type 1 gp120 V3 loop affects virus neutralization. Virology 199:431-438.
5. Bolmstedt, A., S. Olofsson, E. Sjogren-Jansson, S. Jeansson, I. Sjoblom, L. Akerblom, J. E. S. Hansen, and S. L. Hu. 1992. Carbohydrate determinant NeuAc-Galβ(1-4) of N-linked glycans modulates the antigenic activity of human immunodeficiency virus type 1 glycoprotein gp120. J. Gen. Virol. 73:3099-3105.
6. Cheng-Mayer, C., M. Quiroga, J. W. Tung, D. Dina, and J. A. Levy. 1990. Viral determinants of human immunodeficiency virus type 1 T-cell or macrophage tropism, cytopathogenicity, and CD4 antigen modulation. J. Virol. 64:4390-4398.
7. Cheng-Mayer, C., D. Seto, M. Tateno, and J. A. Levy. 1988. Biologic features of HIV-1 that correlate with virulence in the host. Science 240:80-82.
8. Chesebro, B., J. Nishio, S. Perryman, A. Cann, W. O'Brien, I. S. Y. Chen, and K. Wehrly. 1991. Identification of human immunodeficiency virus envelope gene sequences influencing viral entry into CD4-positive HeLa cells, T-leukemia cells, and macrophages. J. Virol. 65:5782-5789.
9. Cho, M. W. Unpublished data.
10. Dalgleish, A., P. C. L. Beverly, P. R. Clapham, D. H. Crawford, M. F. Greaves, and R. A. Weiss. 1984. The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus. Nature (London) 312: 763-767.
11. Davis, D., M. Stephens, C. Willers, and P. J. Lachmann. 1990. Glycosylation governs the binding of antipeptide antibodies to regions of hypervariable amino acid sequence within recombinant gp120 of human immunodeficiency virus type 1. J. Gen. Virol. 71:2889-2898.
12. Fauci, A. S. 1988. The human immunodeficiency virus: infectivity and mechanism of pathogenesis. Science 239:617-622.
13. Fenouillet, E., J. C. Gluckman, and E. Bahraoui. 1990. Role of N-linked glycans of envelope glycoproteins in infectivity of human immunodeficiency virus type 1. J. Virol. 64:2841-2848.
14. Freed, E. O. Unpublished data.
15. Freed, E. O., D. J. Myers, and R. Risser. 1990. Characterization of the fusion domain of the human immunodeficiency virus type 1 envelope glycoprotein gp41. Proc. Natl. Acad. Sci. USA 87:4650-4654.
16. Fukuda, M., A. Deli, J. E. Oates, and M. N. Fukuda. 1984. Structure of branched lactosaminoglycan, the carbohydrate moiety of hand 3 isolated from adult human erythrocytes. J. Biol. Chem. 259:8260-8273.
17. Fukuda, M., H. P. Koeffier. and J. Minowada. 1981. Membrane differentiation in human myeloid cells: expression of unique profiles of cell surface glycoproteins in myeloid leukemic cell lines blocked at different stages of differentiation and maturation. Proc. Natl. Acad. Sci. USA 78:6299-6303.
18. Fukuda, M. N., and G. Matsumura. 1976. Endo-β-galaclosidase of Escherichia freundii. Purification and endoglycosidic action on keratan sulfates, oligosaccharides, and blood group active glycoprotein. J. Biol. Chem. 251: 6218-6225.
19. Gartner, S., P. Markovitz, D. M. Markovitz, M. H. Kaplan, R. C. Gallo, and M. Popovic. 1986. The role of mononuclear phagocytes in HTLV/LAV infection. Science 233:215-219.
20. Gelderbloom, H. R., E. H. S. Hausmann, M. Ozel, G. Pauli, and M. A. Kock. 1987. Fine structure of human immunodeficiency virus (HIV) and immunolocalization of structural proteins. Virology 156:171-176.
21. Gendelman, H. E., J. M. Orenstein, M. A. Martin, C. Ferrua, R. Mitra, T. Phipps, L. A. Wahl, H. C. Lane, A. S. Fauci, D. S. Burke, D. Skillman, and M. S. Meltzer. 1988. Efficient isolation and propagation of human immunodeficiency virus on recombinant colony-stimulating factor 1-treated monocytes. J. Exp. Med. 167:1428-1441.
22. Gerrard, T. L., C. H. Jurgensen, and A. S. Fauci. 1983. Differential effect of monoclonal anti-DR antibody on monocytes in antigen and mitogen-stimulated responses: mechanism of inhibition and relationship to interleukin secretion. Cell. Immunol. 82:394-402.
23. Geyer, H., C. Holschbach, G. Hunsmann, and J. Schneider. 1988. Carbohydrates of human immunodeficiency virus. Structures of oligosaccharides linked to the envelope glycoprotein gp120. J. Biol. Chem. 263:11760-11767.
24. Gram, G. J., A. Hemming, A. Bolmstedt, B. Jamsson, S. Olofsson, L. Akerblom, J. O. Nielsen, and J. E. S. Hansen. 1994. Identification of an N-linked glycan in the V1-loop of HIV-1 gp120 influencing neutralization by anti-V3 antibodies and soluble CD4. Arch. Virol. 139:253-261.
25. Hansen, J. E. S., H. Causen, C. Nielsen, L. S. Teglbjerg, L. L. Hansen, C. M. Nielsen, E. Dabelsteen, L. Mathiesen, S. I. Hakomori, and J. O. Nielsen. 1990. Inhibition of human immunodeficiency virus (HIV) infection in vitro by anticarbohydrate monoclonal antibodies: peripheral glycosylation of HIV envelope glycoprotein gp120 may be a target for virus neutralization. J. Virol. 64:2833-2840.
26. Kowalski, M., J. Potz, L. Basiripour, T. Dorfman, W. C. Goh, E. Terwilliger, A. Dayton, C. Rosen, W. Haseltine, and J. Sodroski. 1987. Functional regions of the envelope glycoprotein of human immunodeficiency virus type 1. Science 237:1351-1355.
27. Koyanagi, Y., S. Miles, R. T. Mitsuyasu, J. E. Merrill, H. V. Vinters, and L. S. Y. Chen. 1987. Dual infection of the central nervous system by AIDS viruses with distinct cellular tropisms. Science 236:819-822.
28. Lazdins, J. K., K. Woods-Cook, M. Walker, and E. Alteri. 1990. The lipophilic muramyl peptide MTP-PE is a potent inhibitor of HIV replication in macrophages. AIDS Res. Hum. Retroviruses 6:1157-1161.
29. Levy, J. A. 1993. Pathogenesis of human immunodeficiency virus infection. Microbiol. Rev. 57:183-289.
30. McDougal, J. S., M. S. Kennedy, J. N. Sligh, S. P. Cort, A. Mawle, and J. K. A. Nicholson. 1986. Binding of HTLV-III/LAV to T4+ cells by a complex of the 110K viral protein and the T4 molecule. Science 231:382-385.
31. McKeating, J. A., A. McKnight, and J. P. Moore. 1991. Differential loss of envelope glycoprotein gp120 from virions of human immunodeficiency virus type 1 isolates: effects on infectivity and neutralization. J. Virol. 65:852-860.
32. O'Brien, W. A., Y. Koyanagi, A. Namazie, J.-Q. Zhao, A. Diagne, K. Idler, J. A. Zack, and I. S. Y. Chen. 1990. HIV-1 tropism for mononuclear phagocytes can be determined by regions of gp120 outside the CD4-binding domain. Nature (London) 348:69-73.
33. Plaas, A. H. K., and S. Wong-Palms. 1993. Biosynthetic mechanisms for the addition of polylactosamine to chondrocyte fibromodulin. J. Biol. Chem. 268:26634-26644.
34. Potts, B. J., W. Maury, and M. A. Martin. 1990. Replication of HIV-1 in primary monocyte cultures. Virology 175:465-476.
35. Prince, A. M., H. Reesink, D. Pascual, B. Horowitz, I. Hewlett, K. K. Murthy, K. E. Cobb, and J. W. Eichberg. 1991. Prevention of HIV infection by passive immunization with HIV immunoglobulin. AIDS Res. Hum. Retroviruses 7:971-973.
36. Rademacher, T. W., R. B. Parekh, and R. A. Dwek. 1988. Glycobiology. Annu. Rev. Biochcm. 57:785-838.
37. Reed, L. J., and H. Muench. 1938. A simple method of estimating fifty per cent endpoints. Am. J. Hyg. 27:493-497.
38. Schneider, M., O. Kaaden, T. D. Copeland, S. Oroszlan, and G. Hunsmann. 1986. Shedding and interspecies type sero-reactivity of the envelope glycopeptide gp120 of the human immunodeficiency virus. J. Gen. Virol. 67:2533-2538.
39. Shibata, R., M. D. Hoggan, C. Broscius, G. Englund, T. S. Theodore, A. Buckler-White, L. O. Arthur, Z. Israel, A. Schultz, H. C. Lane, and M. A. Martin. 1995. Isolation and characterization of a syncytium-inducing, macrophage/T-cell line-tropic human immunodeficiency virus type 1 isolate that readily infects chimpanzee cells in vitro and in vivo. J. Virol. 69:4453-4462.
40. Shioda, T., J. A. Levy, and C. Cheng-Mayer. 1991. Macrophage and T-cell line tropisms of HIV-1 are determined by specific regions of the envelope gp120 gene. Nature (London) 349:167-169.
41. Stein, B. S., and E. G. Engleman. 1990. Intracellular processing of the gp160 HIV-1 envelope precursor. J. Biol. Chem. 265:2640-2649.
42. Stein, B. S., S. D. Gowda, J. D. Lifson, F. C. Penhallow, K. G. Bensch, and E. G. Engleman. 1987. pH independent HIV entry into CD4 positive T cells via virus envelope fusion to the plasma membrane. Cell 49:659-668.
43. 4-(N-acetyl-β-D-glucosaminyl) asparagine amidase from Flavobacterium meningosepticum. J. Biol. Chem. 265:6961-6966.
44. Theodore, T. S., G. Englund, A. Buckler-White, C. E. Buckler, M. A. Martin, and K. W. C. Peden. 1996. Construction and characterization of a stable full-length macrophage-tropic HIV-1 molecular clone that directs the production of high titers of progeny virions. AIDS Res. Hum. Retroviruses 12:191-194.
45. Veronese, F. D., A. L. DeVico, T. D. Copeland, S. Oroszlan, R. C. Gallo, and M. G. Sarngadharan. 1985. Characterization of gp41 as the transmembrane protein coded by the HTLV-III/LAV envelope gene. Science 229:1373-1376.
46. Warrier, S. V., A. Pinter, W. J. Honnen, M. Girard, E. Muchmore, and S. A. Tilley. 1994. A novel, glycan-dependent epitope in the V2 domain of human immunodeficiency virus type 1 gp120 is recognized by a highly potent, neutralizing chimpanzee monoclonal antibody. J. Virol. 68:4636-4642.
47. Westerfelt, P., H. E. Gendelman, and L. Ratner. 1991. Identification of a determinant within the human immunodeficiency virus 1 surface envelope glycoprotein critical for productive infection of primary monocytes. Proc. Natl. Acad. Sci. USA 88:3097-3101.
48. Willey, R. L., J. S. Bonifacino, B. J. Potts, M. A. Martin, and R. D. Klausner. 1988. Biosynthesis, cleavage, and degradation of the human immunodeficiency virus type 1 envelope glycoprotein gp160. Proc. Natl. Acad. Sci. USA 85:9580-9584.
49. Willey, R. L., T. Klimkait, D. M. Frucht, J. S. Bonifacino, and M. A. Martin. 1991. Mutations within the human immunodeficiency virus type 1 gp160 envelope glycoprotein alter its intracellular transport and processing. Virology 184:319-329.
50. Willey, R. L., M. A. Martin, and K. W. C. Peden. 1994. Increase in soluble CD4 binding to and CD4-induced dissociation of gp120 from virions correlates with infectivity of human immunodeficiency virus type 1. J. Virol. 68:1029-1039.
51. Willey, R. L., D. H. Smith, L. A. Lasky, T. S. Theodore, P. L. Earl, B. Moss, D. J. Capon, and M. A. Martin. 1988. In vitro mutagenesis identifies a region within the envelope gene of the human immunodeficiency virus that is critical for infectivity. J. Virol. 62:139-147.
52. Willey, R. L. and T. S. Theodore. Unpublished data.
53. Willey, R. L., T. S. Theodore, and M. A. Martin. 1994. Amino acid substitutions in the human immunodeficiency virus type 1 gp120 V3 loop that change viral tropism also alter physical and functional properties of the virion envelope. J. Virol. 68:4409-4419.
54. Williams, M. A., and R. A. Lamb. 1988. Polylactosaminoglycan modification of a small integral membrane glycoprotein, influenza B virus NB. Mol. Cell. Biol. 8:1186-1196.