The effects of hormone replacement therapy on carbohydrate metabolism and cardiovascular risk factors in surgically postmenopausal cynomolgus monkeys

Metabolism: Clinical and Experimental

Volumn 45, Issue 10, 1996, Pages 1254-1262

  Wagner, Janice D ^a   Martino, Michele A ^a   Jayo, Manuel J ^a   Anthony, Mary S ^a   Clarkson, Thomas B ^a   Cefalu, William T ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; ATHEROSCLEROSIS; CARBOHYDRATE METABOLISM; CORONARY RISK; ESTROGEN THERAPY; FEMALE; GLUCOSE TOLERANCE; INSULIN RESISTANCE; ISCHEMIC HEART DISEASE; MONKEY; NONHUMAN; PRIORITY JOURNAL; RISK FACTOR;

EID: 0029815067     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0026-0495(96)90244-9     Document Type: Article

References (44)

1. Stampfer MJ, Colditz GA: Estrogen replacement therapy and coronary heart disease: A quantitative assessment of the epidemiologic evidence. Prev Med 20:47-63, 1991
2. Barrett-Connor E, Bush TL: Estrogen and coronary heart disease in women. JAMA 265:1861-1867, 1991
3. Wagner JD, Clarkson TB, St. Clair RW, et al: Estrogen and progesterone replacement therapy reduces LDL accumulation in the coronary arteries of surgically postmenopausal cynomolgus monkeys. J Clin Invest 88:1995-2002, 1991
4. Williams JK, Adams MR, Klopfenstein HS: Estrogen modulates responses of atherosclerotic coronary arteries. Circulation 81:1680-1687, 1990
5. Howard G, O'Leary D, Ayad M, et al: Lower insulin sensitivity is related to atherosclerosis in non-diabetics: The Insulin Resistance in Atherosclerosis Study (IRAS). Diabetes 43:188A, 1994 (suppl 1, abstr)
6. Welborn TA, Wearne K: Coronary heart disease and cardiovascular mortality in Busselton with reference to glucose and insulin concentration. Diabetes Care 2:154-160, 1979
7. Pyörälä K, Uusitupa M, Laakso M, et al: Macrovascular complications in relation to hyperinsulinaemia in non-insulin-dependent diabetes mellitus. Diabete Metab 13:345-349, 1987
8. Ronnemaa T, Laakso M, Pyörälä K, et al: High fasting plasma insulin is an indicator of coronary heart disease in non-insulin dependent diabetic patients and nondiabetic subjects. Arterioscler Thromb 11:80-90, 1991
9. Després J-P, Moorjani S, Lupien PJ, et al: Regional distribution of body fat, plasma lipoproteins, and cardiovascular disease. Arteriosclerosis 10:497-511, 1990
10. Lapidus L, Bengtsson C, Larsson B, et al: Distribution of adipose tissue and risk of cardiovascular disease and death: A 12 year follow up of participants in the population study of women in Gothenburg, Sweden. Br Med J 288:1401-1404, 1984
11. Skouby SO: Carbohydrate metabolism and cardiovascular risk, in Lobo R (ed): Treatment of the Postmenopausal Woman. New York, NY, Raven, 1994, pp 263-269
12. Lindheim SR, Presser SC, Ditkoff EC: A possible bimodal effect of estrogen on insulin sensitivity in postmenopausal women and the attenuating effect of added progestin. Fertil Steril 60:664-667, 1993
13. Lindheim SR, Duffy DM, Kojima TK, et al: The route of administration influences the effect of estrogen on insulin sensitivity in postmenopausal women. Fertil Steril 62:1176-1180, 1994
14. Larsson-Cohn U, Wallentin L: Metabolic and hormonal effects of postmenopausal oestrogen replacement treatment. Acta Endocrinol (Copenh) 86:583-596, 1977
15. Godsland IF, Gangar K, Walton C, et al: Insulin resistance, secretion, and elimination in postmenopausal women receiving oral or transdermal hormone replacement therapy. Metabolism 42:846-853, 1993
16. Notelovitz M: Carbohydrate metabolism in relation to hormonal replacement therapy. Acta Obstet Gynecol Scand Suppl 106:51-56, 1982
17. Kumagai S, Holmang A, Bjorntorp P: The effects of oestrogen and progesterone on insulin sensitivity in female rats. Acta Physiol Scand 149:91-97, 1993
18. Cefalu WT, Wagner JD, Bell-Farrow AD, et al: The effects of hormonal replacement therapy on insulin sensitivity in surgically postmenopausal cynomolgus monkeys (Macaca fascicularis). Am J Obstet Gynecol 171:440-445, 1994
19. Stout RW: Insulin and atheroma, 20-year perspective. Diabetes Care 13:631-654, 1990
20. Haarbo J, Marslew U, Gotfredsen A, et al: Postmenopausal hormone replacement therapy prevents central distribution of body fat after menopause. Metabolism 40:1323-1326, 1991
21. DeStefano F, Ford ES, Newman J, et al: Risk factors for coronary heart disease mortality among persons with diabetes. Ann Epidemiol 3:27-34, 1993
22. Baynes JW, Monnier VM (eds): The Maillard Reaction in Aging, Diabetes and Nutrition. New York, NY, Liss, 1989
23. Brownlee M, Vlassara H, Cerami A: Non-enzymatic glycosylation and the pathogenesis of diabetic complications. Ann Intern Med 101:527-537, 1984
24. Reynolds TM: Chemistry of nonenzymatic browning. II. Adv Food Res 14:167-283, 1965
25. Cerami A, Vlassara H, Brownlee M: Protein glycosylation and the pathogenesis of atherosclerosis. Metabolism 34:37-44, 1985 (suppl 1)
26. Schmidt AM, Hori O, Chen JX, et al: Advanced glycation end products interacting with their endothelial receptor induce expression of vascular cell adhesion molecule-1 (VCAM-1) in cultured human endothelial cells and in mice. A potential mechanism for the accelerated vasculopathy of diabetes. J Clin Invest 96:1395-1403, 1995
27. Clarkson TB, Adams MR, Williams JK, et al: Clinical implications of animal models of gender difference in heart disease, in Douglas PS (ed): Cardiovascular Health and Disease in Women. Philadelphia, PA, Saunders, 1993, pp 283-302
28. Wagner JD, Carlson CS, O'Brien TD, et al: Diabetes mellitus and islet amyloidosis in cynomolgus monkeys. Lab Anim Sci 46:36-41, 1996
29. Williams JK, Anthony MS, Honoré EK, et al: Regression of atherosclerosis in female monkeys. Arterioscler Thromb Vasc Biol 15:827-836, 1995
30. Jayo MJ, Rankin SE, Weaver DS, et al: Accuracy and precision of lumbar bone mineral content by dual-energy X-ray absorptiometry in live female monkeys. Calcif Tissue Int 49:438-440, 1991
31. Cefalu WT, Sonntag W, Baynes JW, et al: Caloric restriction decreases age-dependent accumulation of the glycoxidation products NE (carboxymethyl) lysine and pentosidine in rat skin collagen. J Gerontol Biol Sci 50A:B337-B341, 1995
32. Nabulsi AA, Folsom AR, White A, et al: Association of hormone replacement therapy with various cardiovascular risk factors in postmenopausal women. N Engl J Med 328:1069-1075, 1993
33. Barrett-Connor E, Laakso M: Ischemic heart disease risk in post-menopausal women. Effects of estrogen use on glucose and insulin levels. Arteriosclerosis 10:531-534, 1990
34. The Writing Group for the PEPI Trial: Effects of estrogen or estrogen/progestin regimens on heart disease risk factors in postmenopausal women: The Postmenopausal Estrogen/Progestin Interventions (PEPI) Trial. JAMA 273:199-208, 1995
35. Valdes CT, Elkind-Hirsch KE: Intravenous glucose tolerance test: Derived insulin sensitivity changes during the menstrual cycle. J Clin Endocrinol Metab 72:642-646, 1991
36. Wynn V, Godsland I: Effects of oral contraceptives on carbohydrate metabolism. J Reprod Med 31:892-897, 1986
37. Kasdorf G, Kalkhoff RK: Prospective studies of insulin sensitivity in normal women receiving oral contraceptive agents. J Clin Endocrinol Metab 66:846-850, 1988
38. Monnier VM, Kohn RR, Cerami A: Accelerated age-related browning of human collagen in diabetes mellitus. Proc Natl Acad Sci USA 81:583-587, 1984
39. Stern MP, Haffner SM: Body fat distribution and hyperinsulinemia as risk factors for diabetes and cardiovascular disease. Arteriosclerosis 6:123-130, 1986
40. Davies SR, McCloud P, Strauss BJG, et al: Testosterone enhances estradiol's effects on postmenopausal bone density and sexuality. Maturitas 21:227-236, 1995
41. Fujioka S, Matsuzawa Y, Ishikawa K, et al: Contribution of intra-abdominal fat accumulation to the impairment of glucose and lipid metabolism in human obesity. Metabolism 36:54-59, 1987
42. Cefalu WT, Wang ZQ, Werbel S, et al: Contribution of visceral fat mass to the insulin resistance of aging. Metabolism 44:954-959, 1995
43. Cefalu WT, Wagner JD, Wang ZQ, et al: Caloric restriction and cardiovascular aging in cynomolgus monkeys (Macaca fascicularis): First year observations. J Gerontol (in press)
44. Adams MR, Register TC, Golden DL, et al: Medroxyprogesterone acetate antagonizes inhibitory effects of conjugated equine estrogens on coronary artery atherosclerosis. Arterioscler Thromb Vasc Biol (in press)