Binding of clozapine metabolites and analogues to the histamine H3 receptor in rat brain cortex

Archiv der Pharmazie

Volumn 329, Issue 8-9, 1996, Pages 413-416

  Alves Rodrigues, Alexandra ^a   Leurs, Rob ^a   Willems, Edwin ^a   Timmerman, Henk ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

125I iodophenpropit; clozapine analogues; H3 histamine receptor; structure affinity relationship

Indexed keywords

CLOZAPINE; CLOZAPINE DERIVATIVE; DRUG METABOLITE; HISTAMINE H3 RECEPTOR;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BRAIN CORTEX; CONTROLLED STUDY; DRUG RECEPTOR BINDING; MALE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RAT;

ANIMALS; ANTIPSYCHOTIC AGENTS; CEREBRAL CORTEX; CLOZAPINE; MALE; RATS; RATS, WISTAR; RECEPTORS, HISTAMINE H3; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0029814378     PISSN: 03656233     EISSN: None     Source Type: Journal    
DOI: 10.1002/ardp.19963290808     Document Type: Article

References (29)

1. M. Kathmann, E. Schlicker, M. Gothert, Psychopharmacology 1994, 116, 464-468.
2. A. Alves Rodrigues, F.P. Jansen, R. Leurs, G.D. Prell, H. Timmerman, Br. J. Pharmacol 1995, 114, 1523-1524.
3. J. M. Arrang, M. Garbarg, J.C. Schwartz, Nature 1983, 302, 832-337.
4. E. Schlicker, B. Malinowska, M. Kathmann, M. Göthert, Fundam. Clin. Pharmacol. 1994, 8, 128-137.
5. J. C. Schwartz, J.M. Arrang, M. Garbarg, H. Pollard, Agents Actions 1990, 30, 13-23.
6. R. Leurs, R. C. Vollinga, H. Timmerman, Progr. Drug Res. 1995, 45, 107-165.
7. 3 Receptors: The Histamine Receptor, in Receptor Biochemistry and Methodology, J.C. Schwartz and H.L. Haas, Editor. 1992, Wiley-Liss, Inc.: New York. 57-72.
8. S. J. O'Dell, G. J. La Hoste, C. B. Widmark, Synapse 1990, 6, 146-53.
9. H. Karbe, K. Wienhard, K. Hamacher, et al., J. Neural Transm. (Gen. Sect.) 1991, 86, 163-173.
10. T. Brucke, J. Roth, I. Podreka, et al., Lancet 1992, 339-497.
11. L. Farde, A. L. Nordstrom, S. Nyberg, et al., J. Clin. Psychiatry 1994,55 (Suppl. B), 67-9.
12. H.H. Van Tol, J.R. Bunzow, H.C. Guan, et al., Nature 1991, 350, 610-14.
13. E.A. Pehek, B.K. Yamamoto, J. Neurochem. 1994, 63, 2118-2124.
14. R.J. Baldessarini, D. Huston-Lyons, A. Campbell, et al., Br. J. Psychiatry 1992, 160 Suppl., 12-16.
15. F.P. Jansen, T.S. Wu, H.P. Voss, H.W.M. Steinbusch, R.C. Vollinga, B. Rademaker, A. Bast, H. Timmerman, Br. J. Pharmacol. 1994, 113, 355-362.
16. Y.C. Cheng, W.H. Prusoff, Biochem. Pharmacol. 1973, 22, 3099-3108.
17. P.J. Munson, D. Rodbard, Anal. Biochem. 1980, 107, 220-239.
18. N.R. Draper, H. Smith, in Applied Regression Analysis. 1966, Wiley New York, Editor.
19. W.M.P.B. Menge, H. Van der Goot, H. Timmerman, J.L.H. Eersels, J.D.M. Herscheid, J. Lab. Comp. Radiopharm. 1992, 31, 781-786.
20. K. Onodera, A. Yamatodani, T. Watanabe, H. Wada, Prog. Neurobiol. 1994, 42, 685-702.
21. J.C. Schwartz, J.M. Arrang, M. Garbarg, H. Pollard, M. Ruat, Physiol. Rev. 1991, 71, 1-51.
22. F.P. Jansen, B. Rademaker, A. Bast, H. Timmerman, Eur. J. Pharmacol. 1992, 217, 203-205.
23. A.J. Wagstaff, H.M. Bryson, CNS Drugs 1995, 4, 370-400.
24. S. A. Volpicelli, F. Centorrino, P.R. Puopolo, et al., Clin Chem 1993, 39, 1656-1659.
25. E. Schlicker, I. Marr, Nanyn-Schmidelberg's Arch. Pharmacol. 1996, 353, 290-294.
26. H. Van der Goot, M.J.P. Schepers, G.J. Sterk, H. Timmerman, Eur. J. Med. Chem. 1992, 27, 511-517.
27. J. M. Arrang, M. Garbarg, T.T. Quach, M.D. Trung Tuong, E. Yeramian, J.C. Schwartz, Eur. J. Pharmacol. 1985, 111, 73-84.
28. C.R.Ganellin, D. Jayes, Y.S. Khalaf, W. Tertiuk, J.M. Arrang, N. Defontaine, J.C. Schwartz, Collect. Czech. Chem. Commun. 1991, 56, 2448-2455.
29. K. Kieckononowicz, X. Ligneau, J.C. Schwartz, W. Schunack, Arch. Pharm. 1995, 328, 469-472.