Epidemiological evidence for β-carotene in prevention of cancer and cardiovascular disease

European Journal of Clinical Nutrition

Volumn 50, Issue SUPPL. 3, 1996, Pages

  Van Poppel, G ^a  

^a TNO   (Netherlands)

Author keywords

carotene; Cancer; Cardiovascular disease; Epidemiology

Indexed keywords

BETA CAROTENE;

CANCER EPIDEMIOLOGY; CANCER PREVENTION; CANCER RISK; CARDIOVASCULAR DISEASE; CONFERENCE PAPER; DIET; FRUIT; HEART PROTECTION; HUMAN; LUNG CANCER; STOMACH CANCER; VEGETABLE;

BETA CAROTENE; CARDIOVASCULAR DISEASES; FRUIT; HUMANS; NEOPLASMS; RISK FACTORS; VEGETABLES;

EID: 0029814122     PISSN: 09543007     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (33)

1. Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study Group (1994): The effect of vitamin E and β-carotene on the incidence of lung cancer and other cancers in male smokers. N. Engl. J. Med. 330, 1029-1035.
2. Bendich A (1989): Carotenoids and the immune response. J. Nutr. 119, 112-115.
3. Blot WJ, Li J, Taylor PR, Guo W, Dawsey S, Wang GQ, Yang CS, Zheng SF, Gail M & Li GY (1993): Nutrition intervention trials in Linxian China: supplementation with specific vitamin-mineral combinations, cancer incidence, and disease-specific mortality in the general population. J. Natn. Cancer Inst. 85, 1483-1492.
4. de Vet HCW (1989): The puzzling role of vitamin A in cancer prevention (review). Anticancer Res. 9, 145-152.
5. Ewertz M & Gill M (1990): Dietary factors and breast-cancer risk in Denmark. Int. J. Cancer 46, 779-784.
6. Garland M, Willett WC, Manson JE & Hunter DJ (1993): Antioxidants micronutrients and breast cancer. J. Am. Coll. Nutr. 62, 1393S-1402S.
7. Gaziano JM, Manson JE, Branch LG, LaMotte F, Colditz GA, Buring JE & Hennekens CH (1992) Dietary β-carotene and decreased cardiovascular mortality in an elderly cohort. J. Am. Coll. Cardiol. 19, 377A (Abstract).
8. Gey KF, Stähelin HB & Eichholzer M (1993): Poor plasma status of carotene and vitamin C is associated with higher mortality from ischemic heart disease and stroke. Clin. Invest. 71, 3-6.
9. Gramenzi A, Gentile A, Fasoli M, Negri E, Parazzini F & La Vecchia C (1990): Association between certain foods and risk of acute myocardial infarction in women. Br. Med. J. 300, 771-773.
10. Greenberg ER, Baron JA, Stukel TA, Stevens MM, Mandel JS, Spencer SK, Elias PM, Lowe N, Nierenberg DW, Bayrd G, Vance JC, Freeman DH, Clendenning WE & Kwan T (1990): A clinical trial of β-carotene to prevent basal-cell and squamous-cell cancers of the skin. N. Engl. J. Med. 323, 789-795.
11. Greenberg ER, Baron JA, Tosteson TD, Freeman DH, Beck GJ, Bond JH, Colacchio TA, Coller JA, Frankl HD, Haile RW, Mandel JS, Nierenberg DW, Rothstein R, Snover DC, Stevens MM, Summers RW & van Stolk RU (1994): A clinical trial of antioxidant vitamins to prevent colorectal adenoma. N. Engl. J. Med. 331, 141-147.
12. Hill AB (1971): Principles of medical statistics, 9th edn. New York: Oxford University Press.
13. Hunter DJ (1990): Biochemical indicators of dietary intake. In Nutritional epidemiology, ed. W Willett, pp 143-217. New York: Oxford University Press.
14. Hunter DJ, Manson JE, Colditz GA, Stampfer MJ, Rosner B, Hennekens CH, Speizer FE & Willett WC (1993): A prospective study of the intake of vitamins C, E and A and the risk of breast cancer. N. Engl. J. Med. 329, 234-240.
15. Kardinaal AFM, Kok FJ, Ringstad J, Gomez-Aracena J, Mazaev VP, Kohlmeier L, Martin BC, Aro A, Kark JD & Delgado-Rodriguez M (1993): Antioxidants in adipose tissue and risk of myocardial infarction: the Euramic study. Lancet 342, 1379-1384.
16. Knekt P, Aromaa A, Maatela J, Aaran RK, Nikkari T, Hakama M, Hakulinen T, Peto R & Teppo L (1990): Serum vitamin A and subsequent risk cancer; cancer incidence follow-up of the Finnish Mobile Clinic Health Examination Survey. Am. J. Epidemiol. 132, 857-870.
17. Knekt P, Reunanen A, Järvinen R, Sappanen R, Heliovaara M & Aramaaa A (1994): Antioxidant vitamin intake and coronary mortality in a longitudinal population study. Am. J. Epidemiol. 139, 1180-1189.
18. Krinsky NI (1989a): Carotenoids as chemopreventive agents. Prev. Med. 18, 592-602.
19. Krinsky NI (1989b): Antioxidant functions of carotenoids. Free Rad. Biol. Med. 7, 617-635.
20. Morris DL, Kritchevsky SB & Davis CE (1994): Serum carotenoids and coronary heart disease. J. Am. Med. Assoc. 272, 1439-1441.
21. Olson JA (1989): Provitamin A function of carotenoids: the conversion of β-carotene into vitamin A. J. Nutr. 119, 105-108.
22. Palgi A (1981): Association between dietary changes and mortality rates: Israël 1949 to 1977; a trend-free regression model. Am. J. Clin. Nutr. 34, 1569-1583.
23. Peto R, Doll R, Buckley JD & Sporn MB (1981): Can dietary β-carotene materially reduce human cancer rates? Nature 290, 201-208.
24. Rimm EB, Stampfer MJ, Ascherio A, Giovannucci E, Colditz GA & Willett WC (1993): Vitamin E consumption and the risk of coronary heart disease in men. N. Engl. J. Med. 328, 1450-1456.
25. Risch HA, Burch JP, Miller AB, Hill GB, Steele R & Howe GR (1988): Dietary factors and the incidence of cancer of the urinary bladder. Am. J. Epidemiol. 127, 1179-1191.
26. Steinberg D, Parthasarathy S, Carew TE, Khoo JC & Witztum JL (1989): Beyond cholesterol: modifications of low-density lipoprotein that increase its atherogenicity. N. Engl. J. Med. 320, 915-924.
27. Street DA, Comstock GW, Salkeld RM, Schüep W & Klag MJ (1994): Serum antioxidants and myocardial infarction: are low levels of carotenoids and a-tocopherol risk factors for myocardial infarction? Circulation 90, 1154-1161.
28. van Poppel G (1993): Carotenoids and cancer; an update with emphasis on human intervention studies. Eur. J. Cancer 29A(9), 1335-1344.
29. van Poppel G & Goldbohm RA (1995): Epidemiological evidence for β-carotene and cancer prevention. Am. J. Clin. Nutr. 62 (Suppl.), 1393S-1402S.
30. van Poppel G, Kardinaal A, Princen H & Kok FJ (1994): Antioxidants and coronary heart disease. Ann. Med. 26, 429-434.
31. Willett WC (1990): Vitamin A and lung cancer. Nutr. Rev. 48, 201-211.
32. Zhang LX, Cooney RV & Bertram JS (1991): Carotenoids enhance gap junctional communication and inhibit lipid peroxidation in C3H/10T1/2 cells: relationship to their cancer chemopreventive action. Carcinogenesis 12, 2109-2114.
33. Ziegler RG, Subar AF, Craft NE, Ursin G, Patterson BH & Graubard BI (1992): Does β-carotene explain why reduced cancer risk is associated with vegetable and fruit intake? Cancer Res. 52, 2060S-2066S.