Mutation rate in the hypervariable VNTR g3 (D7S22) is affected by allele length and a flanking DNA sequence polymorphism near the repeat array

American Journal of Human Genetics

Volumn 59, Issue 2, 1996, Pages 360-367

  Andreassen, Rune ^a   Egeland, Thore ^b   Olaisen, Bjørnar ^a  

^a UNIVERSITY OF OSLO   (Norway)

^b NORWEGIAN COMPUTING CENTER   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DNA MINISATELLITE;

ALLELE; ARTICLE; BASE PAIRING; CONTROLLED STUDY; DNA FLANKING REGION; DNA POLYMORPHISM; DNA SEQUENCE; GENE CLUSTER; GENE LOCUS; GENE MUTATION; HAPLOTYPE; HUMAN; MUTATION RATE; NUCLEIC ACID BASE SUBSTITUTION; NUCLEOTIDE SEQUENCE; PATERNITY TEST; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SOUTHERN BLOTTING; VARIABLE NUMBER OF TANDEM REPEAT;

ALLELES; BASE SEQUENCE; DNA, SATELLITE; FEMALE; HUMANS; MALE; MINISATELLITE REPEATS; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; MUTAGENESIS; PATERNITY; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; SEQUENCE ANALYSIS, DNA;

EID: 0029814069     PISSN: 00029297     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. Altman DG (1991) Practical statistics for medical research. Chapman Hall, New York
2. Andreassen R, Olaisen B (1994) Study of short alleles in the VNTR locus D7S22 (λg3). In: Olaisen B, Teige B (eds) Proceedings from the XII Nordic meeting of forensic medicine, Lillehammer, August 10-13, pp 156-160
3. Armour JAL, Harris PC, Jeffreys AJ (1993) Allelic diversity at minisatellite MS205 (D16S309): evidence for polarized variability. Hum Mol Genet 2:1137-1145
4. Baumruker T, Sturm R, Herr W (1988) OBP100 binds remarkably degenerate octamer motifs through specific interaction with flanking sequences. Genes Dev 2:1400-1413
5. Buard J, Vergnaud G (1994) Complex recombination events at the hypermutable minisatellite CEB1 (D2S90). EMBO J 13:3203-3210