Effects of early-onset artificial strabismus on pursuit eye movements and on neuronal responses in area MT of macaque monkeys

Journal of Neuroscience

Volumn 16, Issue 20, 1996, Pages 6537-6553

  Kiorpes, Lynne ^a   Walton, Pamela J ^b   O'Keefe, Lawrence P ^a   Movshon, J Anthony ^a   Lisberger, Stephen G ^b  

^a NEW YORK UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

artificial strabismus; binocular interaction; development; eye movements; motion processing; MT; smooth pursuit; visual cortex

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; BINOCULAR VISION; CONTROLLED STUDY; EYE MOVEMENT CONTROL; MACACA; NONHUMAN; PRIORITY JOURNAL; STRABISMUS; VISUAL CORTEX; VISUAL FIELD;

EID: 0029813987     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.16-20-06537.1996     Document Type: Article

References (43)

1. Albright TD (1984) Direction and orientation selectivity of neurons in visual area MT of the macaque. J Neurophysiol 52:1106-1130.
2. Collewijn H (1977) Eye- and head movements in freely moving rabbits. J Physiol (Lond) 266:471-498.
3. Crawford MLJ, Von Noorden GK (1979) The effects of short-term experimental strabismus on the visual system in Macaca mulatta. Invest Ophthalmol Vis Sci 18:496-505.
4. Desimone R, Ungerleider LG (1986) Multiple visual areas in the caudal superior temporal sulcus of the macaque. J Comp Neurol 248:164-189.
5. Dürsteler MR, Wurtz RH (1988) Pursuit and optokinetic deficits following chemical lesions of cortical areas MT and MST. J Neurophysiol 60:940-965.
6. Eggers HM, Blakemore C (1978) Physiological basis of anisometropic amblyopia. Science 201:264-267.
7. Eggers HM, Gizzi MS, Movshon JA (1984) Spatial properties of striate cortical neurons in esotropic macaques. Invest Ophthalmol Vis Sci [Suppl] 25:278.
8. Galyas F (1979) Silver staining of myelin by means of physical development. Neurol Res 1:203-209.
9. Gottlieb JP, MacAvoy MG, Bruce CJ (1993) Smooth eye movements elicited by microstimulation in the primate frontal eye field. J Neurophysiol 69:786-799.
10. Gottlieb JP, MacAvoy MG, Bruce CJ (1994) Neural responses related to smooth pursuit eye movements and their correspondence with electrically elicited smooth eye movements in the primate frontal eye field. J Neurophysiol 72:1634-1653.
11. Grasse K, Lisberger SG (1992) Analysis of a naturally occurring asymmetry in vertical smooth pursuit eye movements in a monkey. J Neurophysiol 67:164-179.
12. Hoffmann K-P, Distler C, Ilg U (1992) Callosal and superior temporal sulcus contributions to receptive field properties in the macaque monkey's nucleus of the optic tract and dorsal terminal nucleus of the accessory optic tract. J Comp Neurol 321:150-162.
13. Hubel DH, Wiesel TN (1965) Binocular interaction in striate cortex of kittens reared with artifical squint. J Neurophysiol 28:1041-1059.
14. Hubel DH, Wiesel TN (1968) Receptive fields and functional architecture of monkey striate cortex. J Physiol (Lond) 195:215-243.
15. Kiorpes L, Boothe RG, Hendrickson AE, Movshon JA, Eggers HM, Gizzi MS (1987) Effects of early unilateral blur on the macaque's visual system. I. Behavioral observations. J Neurosci 7:1318-1326.
16. Kiorpes L, Carlson MR, Alfi D (1989) Development of visual acuity in experimentally strabismic monkeys. Clin Vision Sci 4:95-106.
17. Kiorpes L, Kiper DC, Movshon JA (1993) Contrast sensitivity and vernier acuity in amblyopic monkeys. Vision Res 33:2301-2311.
18. Levitt JB, Kiper DC, Movshon JA (1994) Receptive fields and functional architecture of macaque V2. J Neurophysiol 71:2517-2542.
19. Lisberger SG, Pavelko TA (1989) Directional and topographic organization of the visual inputs for smooth pursuit eye movements in monkeys. J Neurophysiol 61:173-185.
20. Lisberger SG, Westbrook LE (1985) Properties of visual inputs that initiate horizontal smooth pursuit eye movements in monkeys. J Neurosci 5:1662-1673.
21. MacAvoy MG, Gottlieb JP, Bruce CJ (1991) Smooth-pursuit eye movement representation in the primate frontal eye field. Cereb Cortex 1:95-102.
22. Maunsell JHR, Van Essen DC (1983a) Functional properties of neurons in the middle temporal visual area (MT) of the macaque monkey. I. Selectivity for stimulus direction, speed, and orientation. J Neurophysiol 49:1127-1147.
23. Maunsell JHR, Van Essen DC (1983b) Functional properties of neurons in the middle temporal visual area (MT) of the macaque monkey. II. Binocular interactions and sensitivity to binocular disparity. J Neurophysiol 49:1148-1167.
24. Maunsell JHR, Van Essen DC (1983c) The connections of the middle temporal visual area (MT) and their relationship to a cortical hierarchy in the macaque monkey. J Neurosci 3:2563-2583.
25. Merrill EG, Ainsworth A (1972) Glass-coated platinum-plated tungsten microelectrode. Med Biol Eng 10:495-504.
26. Movshon JA, Kiorpes L (1992) Effects of artificial strabmisus on macaque MT. Soc Neurosci Abstr 18:1456.
27. Movshon JA, Eggers HM, Gizzi MS, Hendrickson AE, Kiorpes L, Boothe RG (1987) Effects of early unilateral blur on the macaque's visual system. III. Physiological observations. J Neurosci 7:1340-1351.
28. Movshon JA, Lisberger SG, Kiorpes L, Walton PD, O'Keefe LP (1995) Effects of strabismus on pursuit eye movements and MT neurons in macaque monkeys. Perception 24S:6.
29. Newsome WT, Wurtz RH, Dürsteler MR, Mikami A (1985) Deficits in visual motion perception following ibotenic acid lesions of the middle temporal visual area of the macaque monkey. J Neurosci 5:825-840.
30. Rashbass C (1961) The relationship between saccadic and smooth tracking eye movements. J Physiol (Lond) 159:326-338.
31. Schwartz JD, Lisberger SG (1994) Modulation of the level of smooth pursuit activation by initial tracking conditions in monkeys. Vis Neurosci 11:411-424.
32. Tanaka K, Hikosaka H, Saito H, Yukie F, Fukada Y, Iwai E (1986) Analysis of local and wide-field movements in the superior temporal visual areas of the macaque monkey. J Neurosci 6:134-144.
33. Tychsen L (1993) Motion sensitivity and the origins of infantile strabismus. In: Early visual development, normal and abnormal (Simons K, ed), pp 364-390. New York: Oxford UP.
34. Tychsen L, Lisberger SG (1986a) Maldevelopment of visual motion processing in humans who had strabismus with onset in infancy. J Neurosci 6:2495-2508.
35. Tychsen L, Lisberger SG (1986b) Visual motion processing for the initiation of smooth pursuit eye movements in humans. J Neurophysiol 56:953-968.
36. Van Essen DC, Maunsell JHR, Bixby JL (1981) The middle temporal visual area in the macaque: myeloarchitecture, connections, functional properties and topographic representation. J Comp Neurol 199:293-326.
37. Von Noorden GK (1980) Burian and Von Noorden's binocular vision and ocular motility: theory and management of strabismus. St. Louis: Mosby.
38. Walton PJ, Lisberger SG (1989) Binocular misalignment in infancy causes directional asymmetries in pursuit. Invest Ophthalmol Vis Sci [Suppl] 30:304.
39. Wiesel TN (1982) Postnatal development of the visual cortex and the influence of environment. Nature 299:583-591.
40. Wurtz RH (1969) Visual receptive fields of striate cortex neurons in awake monkeys. J Neurophysiol 32:727-742.
41. Zeki SM (1974a) Cells responding to changing image size and disparity in the cortex of the rhesus monkey. J Physiol (Lond) 242:827-841.
42. Zeki SM (1974b) Functional organization of a visual area in the posterior bank of the superior temporal sulcus of the rhesus monkey. J Physiol (Lond) 236:549-573.
43. Zeki SM (1978) Uniformity and diversity of structure and function in rhesus monkey prestriate visual cortex. J Physiol (Lond) 277:273-290.