Nitric oxide and liver injury in alcohol-fed rats after lipopolysaccharide administration

Alcoholism: Clinical and Experimental Research

Volumn 20, Issue 6, 1996, Pages 1065-1070

  Chamulitrat, Walee ^a   Spitzer, John J ^a  

^a LOUISIANA STATE UNIV MEDICAL CENTER   (United States)

Author keywords

Endotoxin; EPR Spectroscopy; Ethanol; Liver Injury; Nitric Oxide

Indexed keywords

ALANINE AMINOTRANSFERASE; ALCOHOL; AMINOGUANIDINE; AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; ENDOTOXIN; HEMOGLOBIN; LIPOPOLYSACCHARIDE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ALCOHOL CONSUMPTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELECTRON SPIN RESONANCE; ENDOTOXEMIA; LIVER BIOPSY; LIVER INJURY; MALE; NONHUMAN; PATHOGENESIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT;

ANIMALIA;

EID: 0029813873     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1530-0277.1996.tb01947.x     Document Type: Article

References (37)

1. Bode C, Kugler V, Bode J: Endotoxemia in patients with alcoholic and nonalcoholic cirrhosis and in subjects with no evidence of chronic liver disease following acute alcohol excess. J Hepatol 4:8-14, 1987
2. 2. Am J Pathol 142:367-373, 1993
3. Bhagwandeen B, Apte M, Manwarring L, Dickenson J: Endotoxin induced hepatic necrosis in rats on an alcohol diet. J Pathol 152:47-53, 1987
4. Honchel R, Ray MB, Marsano L, Cohen D, Lee E, Sheldlofky S, McClain CJ: Tumor necrosis factor in alcohol enhanced endotoxin liver injury. Alcohol Clin Exp Res 16:665-669, 1992
5. Hansen J, Cherwitz DL, Allen JI: The role of tumor necrosis factor-α in acute endotoxin-induced hepatotoxicity in ethanol-fed rats. Hepatology 20:461-474, 1994
6. Bird GLA, Sheron N, Goka AKJ, Alexander GJ, Williams RS: Increased plasma tumor necrosis factor in severe alcoholic hepatitis. Ann Intern Med 112:917-920, 1990
7. McClain CJ, Cohen DA: Increased tumor necrosis factor production by monocytes in alcoholic hepatitis. Hepatology 9:349-351, 1989
8. Mills LR, Scheuer PJ: Hepatic sinusoidal macrophages in alcoholic liver disease. J Pathol 147:127-132, 1985
9. Bautista AP, D'Souza NB, Lang CH, Spitzer JJ: Modulation of F-met-leu-phe induced chemotactic activity and Superoxide production by neutrophils during chronic ethanol intoxication. Alcohol Clin Exp Res 16:788-794, 1992
10. Adachi Y, Bradford BU, Gao W, Bojes HK, Thurman RG: Inactivation of Kupffer cells prevents early alcohol-induced liver injury. Hepatology 20:453-460, 1994
11. Bautista AP, Spitzer JJ: Postbinge effects of acute alcohol intoxication on hepatic free radical formation. Alcohol Clin Exp Res 20:502-509, 1996
12. Deaciuc IV, D'Souza NB, Spitzer JJ: Tumor necrosis factor-α cell-surface receptors of liver parenchymal and nonparenchymal cells during acute and chronic alcohol administration to rats. Alcohol Clin Exp Res 19:332-338, 1995
13. Billiar TR, Curran RD, Stuehr DJ, Stadler J, Simmons RL, Murray SA: Inducible cytosolic enzyme activity for the production of nitrogen oxides from L-arginine in hepatocytes. Biochem Biophys Res Commun 168:1034-1040, 1990
14. Spitzer JA: Cytokine stimulation of nitric oxide formation and differential regulation in hepatocytes and nonparenchymal cells of endotoxemic rats. Hepatology 19:217-228, 1994
15. Greenberg SS, Xie J, Wang Y, Malinski T, Summer WR, McDonough K: Escherichia coli-induced inhibition of endotheliumdependent relaxation and gene expression and release of nitric oxide is attenuated by chronic alcohol ingestion. Alcohol 11:53-60, 1994
16. Nanji AA, Greenberg SS, Tahan SR, Fogt F, Loscalzo J, Sadradeh SMH, Xie J, Stamler JS: Nitric oxide production in experimental alcoholic liver disease in the rat: Role in protection from injury. Gastroenterology 109:899-907, 1995
17. Wang J-F, Greenberg SS, Spitzer JJ: Chronic alcohol administration stimulates nitric oxide formation in the rat liver with or without pretreatment by lipopolysaccharide. Alcohol Clin Exp Res 19:387-393, 1995
18. Henry Y, Ducrocq C, Drapier J-C, Servent D, Pellat C, Guissani A: Nitric oxide, a biological effector. Electron paramagnetic resonance detection of nitrosyl-iron-protein complexes in whole cells. Eur Biophys J 20:1-15, 1991
19. Lang CH, Bagby GJ, Blakesley HL, Spitzer JJ: Importance of hyperglucagonemia in eliciting the sepsis-induced increase in glucose production. Circ Shock 29:181-192, 1989
20. 3+ in MgO. Phys Rev 105:801-805, 1957
21. Lai C-S, Komarov AM: Spin trapping of nitric oxide produced in vivo in septic-shock mice. FEBS Lett 345:120-124, 1994
22. Archer S: Measurement of nitric oxide in biological models. FASEB J 7:349-360, 1993
23. Kosaka H, Sawai Y, Sakaguchi H, Kumura E, Harada N, Watanabe M, Shiga T: ESR spectral transition by arteriovenous cycle in nitric oxide hemoglobin of cytokine-treated rats. Am J Physiol 266:C1400-C1405, 1994
24. Misko TP, Moore WM, Kasten TP, Nickols GA, Corbett JA, Tilton RG, McDaniel ML, Williamson RJ, Currie MG: Selective inhibition of the inducible nitric oxide synthase by aminoguanidine. Eur J Pharmacol 233:119-125, 1993
25. Reinke LA, Lai EK, Dubose CM, McCay PB: Reactive free radical generation in vivo in heart and liver of ethanol-fed rats: Correlation with radical formation in vitro. Proc Natl Acad Sci USA 84:9223-9227, 1987
26. Knecht KT, Thurman RG, Mason RP: Role of Superoxide and trace transition metals in the production of α-hydroxyethyl radical from ethanol by microsomes from alcohol dehydrogenase-deficient deermice. Arch Biochem Biophys 303:339-348, 1993
27. Boveris A, Fraga CG, Varsavsky AI, Koch OR: Increased chemiluminescence and Superoxide production in the liver of chronically ethanol-treated rats. Arch Biochem Biophys 227:534-541, 1983
28. Kukielka E, Dicker E, Cederbaum AI: Increased production of reactive oxygen species by rat liver mitochondria after chronic ethanol treatment. Arch Biochem Biophys 309:377-386, 1994
29. Bautista AP, Spitzer JJ: Hepatic Superoxide formation during acute or chronic ethanol intoxication. Adv Biosci 86:211-218, 1993
30. D'Souza NB, Bagby GJ, Nelson S, Lang CH, Spitzer JJ: Acute alcohol infusion suppresses endotoxin-induced serum tumor necrosis factor. Alcohol Clin Exp Res 13:295-298, 1989
31. Spolarics Z, Spitzer JJ, Wang JF, Xie J, Kolls J, Greenberg S: Alcohol administration attenuates LPS-induced expression of inducible nitric oxide synthase in Kupffer and hepatic endothlial cells. Biochem Biophys Res Comm 197:606-611, 1993
32. Tsuji S, Kawano S, Michida T, Masuda E, Nagano K, Takei Y, Fusamoto H, Kamada T: Ethanol stimulates immunoreactive endothelin-1 and -2 release from cultured human umbilical vein endothelial cells. Alcoholism 16:347-349, 1992
33. Miyajima T, Kotake Y: Spin trapping agent, phenyl N-tert-butyl nitrone, inhibits induction of nitric oxide synthase in endotoxin-induced shock in mice. Biochem Biophys Res Commun 215:114-121, 1995
34. Garcia-Ruiz C, Morales A, Coleli A, Ballesta A, Rodes J, Kaplowitz N, Feernandez-Checa JC: Feeding S-adenosyl-L-methionine attenuates both ethanol-induced depletion of mitochondrial function in periportal and perivenous rat hepatocytes. Hepatology 21:207-214, 1995
35. Beckman JS, Beckman TW, Chen J, Marshall PA, Freeman BA: Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and Superoxide. Proc Natl Acad Sci USA 87:1620-1624, 1990
36. Rubbo H, Radi R, Trujillo M, Telleri R, Kalyanaraman B, Barnes S, Kirk M, Freeman BA: Nitric oxide regulation of Superoxide and peroxynitrite-dependent lipid peroxidation. J Biol Chem 269:26066-26075, 1994
37. G-monomethyl-L-arginine inhibits endotoxin-induced nitrite/nitrate biosynthesis while promoting hepatic damage. J Leukoc Biol 48:565-569, 1990