Limited role for nitric oxide in mediating cerebrovascular control of newborn piglets

Archives of Disease in Childhood: Fetal and Neonatal Edition

Volumn 75, Issue 2, 1996, Pages

  Patel, J ^a   Pryds, O ^c   Roberts, I ^a   Harris, D ^b   Edwards, A D ^a  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

^b Department of Anaesthesia ^*

^c Rigshospitalet   (Denmark)

Author keywords

133Xenon clearance; Carbon dioxide reactivity; Cerebral blood flow; L nitro arginine methyl ester

Indexed keywords

ISOFLURANE; MIDAZOLAM; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; XENON 133;

ANIMAL MODEL; ARTERIAL CARBON DIOXIDE TENSION; ARTICLE; BRAIN BLOOD FLOW; BRAIN CIRCULATION; ENZYME INHIBITION; INHALATIONAL DRUG ADMINISTRATION; INTRAMUSCULAR DRUG ADMINISTRATION; NEWBORN; NONHUMAN; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; SWINE;

ANIMALS; ANIMALS, NEWBORN; CARBON DIOXIDE; CEREBROVASCULAR CIRCULATION; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PARTIAL PRESSURE; SWINE; XENON RADIOISOTOPES;

EID: 0029813729     PISSN: 13592998     EISSN: 14682052     Source Type: Journal    
DOI: 10.1136/fn.75.2.F82     Document Type: Article

References (39)

1. Pape KE, Wigglesworth JS. Haemorrhage, ischaemia and the perinatal brain. London: Spastics International Medical publications, 1979.
2. Lou HC, Skov H, Pedersen H. Low cerebral blood flow: a risk factor in the neonate. J Pediatr 1979;95:606-9.
3. Iadecola C, Pelligrino DA, Moskowitz MA, Lassen NA. Nitric oxide synthase inhibition and cerebrovascular regulation. J Cereb Blood Flow Metab 1994;14:175-92.
4. Faraci FM, Brian JE. Nitric oxide and the cerebral circulation. Stroke 1994;25:692-703.
5. McPherson RW, Kirsch JR, Ghaly RF, Traystman RJ. Effect of nitric oxide synthase inhibition on the cerebral vascular response to hypercapnia in primates. Stroke 1995; 26:682-7.
6. Iadecola C, Xiaohong XU. Nitro-L-arginine attenuates hypercapnic cerebrovasodilation without affecting cerebral metabolism. Am J Physiol 1994;266:R518-25.
7. Malinski T, Bailey F, Zhang ZG, Chopp M. Nitric oxide measured by a porphyinic microsensor in rat brain after transient middle cerebral artery occlusion. J Cereb Blood Flow Metab 1993;13:355-8.
8. Carreau A, Duval D, Poignet H, Scatton B, Vige X, Nowicki JP. Neuroprotective efficacy of N ω-nitro-L-arginine after focal cerebral ischaemia in the mouse and inhibition of cortical nitric oxide synthase. Eur J Pharmacol 1994; 25:241-9.
9. Nishikawa T, Kirsch JR, Koehler RC, Miyabe M, Traystman RJ. Nitric oxide synthase reduces caudate injury following transient focal ischaemia in cats. Stroke 1994;25:877-85.
10. Armstead WM, Mirro R, Busija DW, Leffler CWJ. Permissive role of prostanoids in acetylcholine-induced cerebral vasoconstriction. J Pharmacol Exp Ther 1989;251:1012-19.
11. Meadow W, Rudinsky B, Anthony B, Lozon M, Randle C, Hipps R. The role of prostaglandins and endothelium-derived relaxation factor in the regulation of cerebral blood flow and cerebral oxygen utilization in the piglet: operationalizing the concept of an essential circulation. Pediatr Res 1994;35:649-56.
12. Takei Y, Edwards AD, Lorek A, Peebles DM, Belai A, Cope-M, et al. Effects of N-omega-nitro-L-arginine methyl ester on the cerebral circulation of newborn piglets quantified in vivo by near-infrared spectroscopy. Pediatr Res 1993;34:354-9.
13. 133Xenon clearance in preterm neonates with respiratory distress. Internal validation of CBF as a measure of global cerebral blood flow. Scand J Clin Lab Invest 1988;48:637-78.
14. Mallett BL, Veall N. The partition of trace amounts of Xenon between human blood and brain tissue at 37°C. Phys Med Biol 1965;10:375-80.
15. Obrist WD, Wilkinson WE. The non-invasive Xe-133 method. Evaluation of CBF indices. In: Bes A, Geraud G, eds. Cerebral circulation and neurotransmitters. Amsterdam: Excerpta Medica, 1980:119-24.
16. Pryds O, Schneider S. Aminophylline reduces cerebral blood flow in stable, preterm infants without affecting the visual evoked potential. Eur J Pediatr 1991;150:366-9.
17. Marcus ML, Bischof CJ, Heistad DD. Comparison of microsphere and Xenon-133 clearance method in measuring skeletal muscle and cerebral blood flow. Circ Res 1981; 48:748-61.
18. Skov L, Pryds O, Greisen G. Estimating cerebral blood flow in newborn infants: comparison of near infrared spectroscopy and 133Xe clearance. Pediatr Res 1991;30:570-3.
19. Bucher HU, Edwards AD, Lipp AE, Duc G. Comparision between near infrared spectroscopy and 133-Xenon clearance for estimation of cerebral blood flow in critically ill preterm infants. Pediatr Res 1993;33:56-60.
20. Tomita M, Gotoh F. Local cerebral blood flow values as estimated with diffusible tracers: validity of assumptions in normal and ischemic tissue. J Cereb Blood Flow Metab 1981;1:403-11.
21. Wootton R, Flecknall PA, John M. Accurate measurement of cerebral metabolism in the conscious, unrestrained neonatal piglet. Biol Neonate 1982;41:209-20.
22. Greenberg RS, Helfaer MA, Kirsch JR, Moore LE, Traystman RJ. Nitric oxide synthase inhibition with NG-monomethyl-L-arginine reversibly decreases cerebral blood flow in piglets. Crit Care Med 1994;22:384-92.
23. Kovach AG, Szabo C, Benyo Z, Csaki C, Greenberg JH, Reivich M. Effects of NG-nitro-L-arginine and L-arginine on regional cerebral blood flow in the cat. J Physiol 1992; 449:183-96.
24. Tanaka K, Gotoh F, Gomi S, Takashima S, Mihara B, Shirai T, et al. Inhibition of nitric oxide synthesis induces a significant reduction in local cerebral blood flow in the rat. Neurosci Lett 1991;127:129-32.
25. Griffith TM, Edwards DH, Davies RL, Harrison TJ, Evans KT. EDRF coordinates the behaviour of vascular resistance vessels. Nature 1987;329:442-5.
26. Pelligrino DA, Koenig HM, Albrecht RF. Nitric oxide synthesis and regional cerebral blood flow responses to hypercapnia and hypoxia in the rat. J Cereb Blood Flow Metab 1993;13:80-7.
27. Sandor P, Komjati K, Reivich M, Nyary I. Major role of nitric oxide in the mediation of regional CO2 responsiveness of the cerebral and spinal cord vessels of the cat. J Cereb Blood Flow Metab 1994;14:49-58.
28. Saito S, Wilson DA, Hanley DF, Traystman RJ. Nitric oxide modulates cerebral vessel tone and depresses cerebrovascular resistance changes to carbon dioxide in anaesthetised dogs. J Cereb Blood Flow Metab 1993;13:S153.
29. Faraci FM, Breese KR, Heistad DD. Cerebral vasodilation during hypercapnia: role of glibenclamide-sensitive potassium channels and nitric oxide. Stroke 1994;25:1679-83.
30. Adachi T, Inanami O, Sato A. Nitric oxide (NO) is involved in increased cerebral cortical blood flow following stimulation of the nucleus basalis of Meynert in anesthetized rats. Neurosci Lett 1992;139:201-4.
31. Dieguez G, Garcia JL, Fernandez N, Garcia Villalon AL, Monge L, Gomez B. Role of NO in goat basal cerebral circulation and after vasodilatation to hypercapnia or brief ischemias. Am J Physiol 1993;265:R1410-15.
32. Sokoloff L, Kennedy C, Adachi K, Wang S, Takahashi S, Melzer P. Effects of nitric oxide synthase on resting cerebral blood flow and on changes induced by hypercapnia or local functional activity. In: Krieglstein J, Oberpichler-Schwenk H, eds. Pharmacology of cerebral ischemia. Stuttgart: Wissenschaftliche Verlagsgesellschaft, 1992:371-81.
33. Armstead WM, Zuckerman SL, Shibata M, Parfenova H, Leffler CW. Different pial arteriolar responses to acetylcholine in the newborn and juvenile pig. J Cereb Blood Flow Metab 1994;14:1088-95.
34. Wyatt JS, Edwards AD, Cope M, Delpy DT, McCormick DC, Potter A, et al. Response of cerebral blood volume to changes in arterial carbon dioxide tension in preterm and term infants. Pediatr Res 1991;29:553-7.
35. Kumano H, Furuya H, Yomosa H, Nagahata T, Okuda T, Sakaki T. Response of pial vessel diameter and regional cerebral blood flow to CO2 during midazolam administration in cats. Acta Anaesthesiol Scand 1994;38:729-33.
36. McPherson RW, Briar JE, Traystman RJ. Cerebrovascular responsiveness to carbon dioxide in dogs with 1.4% and 2.8% isoflurane. Anesthesiology 1989;70:843-50.
37. Zellets TM, Vanhoutte PM. Endothelium-dependent relaxation of piglet pulmonary arteries augment with maturation. Pediatr Res 1991;30:176-80.
38. Liu SF, Hislop AA, Haworth SG, Barnes PJ. Developmental changes in endothelium-dependent pulmonary vasodilation in pigs. Br J Pharmacol 1992;106:324-30.
39. Levy M, Tulloh RM, Hiroyoshi K, Stuart-Smith K, Haworth SG. Maturation of the contractile response and its endothelial modulation in newborn porcine intrapulmonary arteries. Pediatr Res 1995;38:25-9.