Pharmacological basis for hepatic drug metabolism in sheep

Veterinary Research

Volumn 27, Issue 4-5, 1996, Pages 363-372

  Galtier, P ^a   Alvinerie, M ^a  

^a CEMAGREF   (France)

Author keywords

benzimidazole; biotransformation; liver; parasitism; sheep

Indexed keywords

ALBENDAZOLE; CYTOCHROME P450; CYTOCHROME P450 ISOENZYME; DRUG METABOLIZING ENZYME; LIVER ENZYME; MEBENDAZOLE; PENTOBARBITAL; PHENAZONE; TIABENDAZOLE; UNSPECIFIC MONOOXYGENASE;

ANIMAL EXPERIMENT; CONTROLLED STUDY; DRUG METABOLISM; LIVER METABOLISM; NONHUMAN; ORAL DRUG ADMINISTRATION; REVIEW; SHEEP;

ANIMALIA; FASCIOLA HEPATICA; HEPATICA; OVIS; OVIS ARIES; PARALICHTHYS DENTATUS;

EID: 0029813161     PISSN: 09284249     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (30)

1. Alvinerie M, Tufenkji AE, Houin G, Toutain PL, Galtier P (1989) Comparative incidence of experimental fascioliasis on corticosteroid pharmacokinetics in sheep. Comp Biochem Physiol 94C, 81-66
2. Braun JP, Bezille P, Galtier P, Rico AG, Ouedraogo G (1992) Effects of age on the distribution of some enzymes in the organs of sheep. Small Ruminant Res 9, 149-156
3. Cooper BS, Hawk HW (1978) Effect of liver microsome enzyme-inducing drugs on blood serum pentobarbital clearance and sleep time in sheep and rabbits. Am J Vet Res 39, 649-652
4. Cresteil T (1987) Regulation of drug-metabolizing enzymes during the perinatal period in rat and human liver. Bioessays 7, 120-124
5. Cresteil T, Beaune P, Celier C, Leroux JP, Guengerich FP (1986) Cytochrome P450 isoenzyme content and monooxygenase activities in rat liver: effect of ontogenesis and pretreatment by phenobarbital and 3-methylcholanthrene. J Pharmacol Exp Ther 236, 269-276
6. Dvorchick BH, Woodward G, Sitar DS, Tweed WA (1986) Hydroxylation and glucuronidation of various xenobiotics by hepatic microsomes from the fetal lamb, pregnant ewe and human fetus. Dev Pharmacol Ther 9, 282-289
7. Facino RM, Carini M, Genchi R (1984) Impaired in vitro metabolism of flukicidal agent nitroxynit by hepatic microsomal cytochrome P450 in bovine fascioliasis. Toxicol Lett 20, 231-236
8. Farrell GC, Cooksley WGE, Powell LW (1979) Drug metabolism in liver disease activity of hepatic microsomal metabolizing enzymes. Clin Pharmacol Ther 26, 483-492
9. Galtier P, Larrieu G, Tufenkji AE, Franc M (1986a) Incidence of experimental fascioliasis on the activity of drug metabolizing enzymes in lamb liver Drug Metab Dispos 14, 137-141
10. Galtier P, Larrieu G, Beaune P (1986b) Characterization of the microsomal cytochrome P450 species inhibited in rat liver in the course of fascioliasis. Biochem Pharmacol 35, 4345-4347
11. Galtier P, Alvinerie M, Plusquellec Y, Tufenkji AE, Houin G (1991) Decrease in albendazole sulphonation during experimental fascioliasis in sheep. Xenobiotica 21, 917-924
12. Galtier P, Kaddouri M, Eeckhoutte C (1993) Compared N-demethylation of veterinary drugs by microsomes from normal and fluke-infected sheep livers. J Vet Pharmacol Ther 16, 106-109
13. Galtier P, Coulet M, Sutra JF, Biro-Sauveur B, Alvinerie M (1994) Fasciola hepatica: mebendazole and thiabendazole pharmacokinetics in sheep. Exp Parasitol 79, 166-176
14. Gyurik RJ, Chow AW, Zaber B, Brunner EL, Miller JA, Villani A, Petka LA (1981) Metabolism of albendazole in cattle, sheep, rats and mice. Drug Metab Dispos 9, 503-508
15. Huan JY, Cheeke PR, Bulher DR, Galtier P (1995) Species differences in the hepatic microsomal enzyme metabolism of pyrrolizidine alkaloids. Proc VII Int Congr Toxicol, Seattle, July 1995, Intern Toxicol 7, 35
16. Huffman DH, Shoeman DW, Azarnoff DL (1974) Correlation of the plasma elimination of antipyrine and the appearance of 4-hydroxyantipyrine in the urine of man. Biochem Pharmacol 23, 197-201
17. Kaddouri M, Larrieu G, Eeckhoutte C, Galtier P (1990) The development of drug-metabolizing enzymes in female sheep liver. J Vet Pharmacol Ther 13, 340-349
18. Kaddouri M, Brasset N, Alvinerie M, Eeckhoutte C, Bonfils C, Derancourt J (1992) Ontogenic development of liver progesterone metabolism in female sheep. Contribution of cytochrome P4502B and P4503A subfamilies. J Steroid Biochem Mol Biol 42, 499-508
19. Matsubara T, Hirose K, Hatakeyama H, Jyoyama H, Touchi A, Otsubo S (1988) Effect of nonsteroidal anti-inflammatory drug 480156-S on hepatic drug-metabolizing activity and pharmacological action of diazepam and pentobarbital in rats. Folia Pharmacol 92, 201-203
20. Paterson JYF, Harrison FA, Sheldrick EL, Heap RB (1983) An improved model of the distribution and metabolism of progesterone and 20α-dehydroprogesterone in sheep. J Reprod Fertil 68, 81-90
21. Peggins JO, Shipley LA, Weiner M (1984) Characterization of age-related changes in hepatic drug metabolism in miniature swine. Drug Metab Dispos 12, 379-381
22. Pineau T, Galtier P, Bonfils C, Derancourt J, Maurel P (1990) Purification of a sheep liver cytochrome P450 from the P450IIIA gene subfamily. Its contribution to the N-dealkylation of veterinary drugs. Biochem Pharmacol 39, 901-909
23. Shoaf SE, Schwark WS, Guard CL, Babish JG (1987) The development of hepatic drug-metabolizing enzymes activity in the neonatal calf and its effect on drug disposition. Drug Metab Dispos 15, 676-681
24. Short CR, Stith RD (1973) Perinatal development of hepatic mixed function oxidase activity in swine. Biochem Pharmacol 22, 1309-1319
25. Smith GS, Watkins JB, Thomson TN, Rozman K, Klaassen CD (1984) Oxidative and conjugative metabolism of xenobiotics by livers of cattle, sheep, swine and rats. J Anim Sci 58, 386-395
26. Tufenkji AE, Alvinerie M, Pineau T, Boulard C, Galtier P (1988) Incidence of a subclinical fascioliasis on antipyrine clearance and metabolite excretion in sheep. Xenobiotica 18, 357-364
27. Tufenkji AE, Alvinerie M, Larrieu G, Houin G, Galtier P (1991) Pharmacokinetics of ampicillin and pentobarbital in the course of subclinical fascioliasis. Res Vet Sci 50, 75-80
28. Van Bezoijen CFA (1984) Influence of age-related changes in rodent liver morphology and physiology on drug metabolism Mech Ageing Dev 25, 1-22
29. Wang LH, Zakim D, Rudolph AM, Benet LZ (1986) Developmental alterations in hepatic UDP-glucuronosyltransferase. A comparison of the kinetic properties of enzymes from adult sheep and fetal lambs. Biochem Pharmacol 35, 3065-3070
30. Wisniewski JA, Moody DE, Hammock BD, Shull LR (1987) Interlobular distribution of hepatic xenobiotic metabolizing enzyme activities in cattle, goat and sheep. J Anim Sci 64, 210-215