Characterization of experimentally induced, nonaflatoxigenic variant strains of Aspergillus parasiticus

Applied and Environmental Microbiology

Volumn 62, Issue 9, 1996, Pages 3399-3404

  Kale, Shubha P ^a   Cary, Jeffrey W ^b   Bhatnagar, Deepak ^b   Bennett, J W ^c  

^a XAVIER UNIVERSITY OF LOUISIANA   (United States)

^b SOUTHERN REGIONAL RESEARCH CENTER   (United States)

^c Tulane University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AFLATOXIN; RNA;

AFLATOXICOSIS; ARTICLE; ASPERGILLUS PARASITICUS; CHEMICAL CARCINOGENESIS; GENE MUTATION; ISOLATION PROCEDURE; REGULATOR GENE; STRAIN DIFFERENCE; STRUCTURE ANALYSIS; TRANSCRIPTION REGULATION;

ASPERGILLUS PARASITICUS; FUNGI;

EID: 0029812688     PISSN: 00992240     EISSN: None     Source Type: Journal    
DOI: 10.1128/aem.62.9.3399-3404.1996     Document Type: Article

References (31)

1. Adye, J., and R. I. Mateles. 1964. Incorporation of labelled compounds into aflatoxins. Biochim. Biophys. Acta 86:418-420.
2. Bennett, J. W. 1979. Aflatoxins and anthraquinones from diploids of Aspergillus parasiticus. J. Gen. Microbiol. 113:127-136.
3. Bennett, J. W., and S. B. Christensen. 1983. New perspectives on aflatoxin biosynthesis. Adv. Appl. Microbiol. 29:53-92.
4. Bhatnagar, D., K. C. Ehrlich, and T. E. Cleveland. 1992. Oxidation-reduction reactions in biosynthesis of secondary metabolites, p. 255-286. In D. Bhatnagar, E. B. Lillehoj, and D. K. Arora (ed.) Handbook of applied mycology, vol. 5. Mycotoxins in ecological systems. Marcel Dekker, Inc., New York.
5. Bradshaw, R. E., J. W. Bennett, and J. F. Peberdy. 1983. Parasexual analysis of Aspergillus parasiticus. J. Gen. Microbiol. 129:2117-2123.
6. Chang, P.-K., J. W. Cary, D. Bhatnagar, T. E. Cleveland, J. W. Bennett, J. E. Linz, C. P. Woloshuk, and G. A. Payne. 1993. Cloning of the Aspergillus parasiticus apa-2 gene associated with the regulation of aflatoxin biosynthesis. Appl. Environ. Microbiol. 59:3273-3279.
7. Chang, P.-K., K. C. Ehrlich, J. Yu, D. Bhatnagar, and T. E. Cleveland. 1995. Increased expression of Aspergillus parasiticus aflR, encoding a sequence-specific DNA-binding protein, relieves nitrate inhibition of aflatoxin biosynthesis. Appl. Environ. Microbiol. 61:2372-2377.
8. Cole, R. J., and R. H. Cox. 1981. Handbook of toxic fungal metabolites. Academic Press, Inc., New York.
9. Cotty, P., and D. Bhatnagar. 1994. Variability among atoxigenic Aspergillus flavus strains in ability to prevent aflatoxin contamination and production of aflatoxin biosynthetic pathway enzymes. Appl. Environ. Microbiol. 60:2248-2251.
10. Filtenborg, O., J Frisvad, and U. Thrane. 1990. The significance of yeast extract composi n metabolite production in Penicillium, p. 433-441. In R. A. Samson I. Pitt (ed.), Modern concepts in Penicillium and Aspergillus clas n. Plenum Press, New York.
11. Floyd, J. C., J ls III, and J. W. Bennett. 1987. Biotransformation of sterigmatocyst osence of aflatoxin biotransformation by blocked mutants of Asper asiticus. Exp. Mycol. 11:109-114.
12. Goldblatt, L. Aflatoxins: scientific background, control and implications. Academic Press, Inc., New York.
13. 1 as precursors. J. Gen. Microbiol. 134:661-667.
14. Kale, S. P., and J. W. Bennett. 1992. Strain instability in filamentous fungi, p. 311-332. In D. Bhatnagar, E. B. Lillehoj, and D. K. Arora (ed.), Handbook of applied mycology, vol. 5. Mycotoxins in ecological systems. Marcel Dekker, Inc., New York.
15. Kale, S. P., D. Bhatnagar, and J. W. Bennett. 1994. Isolation and characterization of morphological variants of Aspergillus parasiticus deficient in secondary metabolite production. Mycol. Res. 98:645-652.
16. Keller, N. P., T. E. Cleveland, and D. Bhatnagar. 1992. A molecular approach towards understanding aflatoxin production, p. 287-310. In D. Bhatnagar, E. B. Lillehoj, and D. K. Arora (ed.), Handbook of applied mycology, vol. 5. Mycotoxins in ecological systems. Marcel Dekker, Inc., New York.
17. Lee, L. S. 1989. Metabolic precursor regulation of aflatoxin formation in toxigenic and non-toxigenic strains of Aspergillus flavus. Mycopathologia 107:127-131.
18. Li, A., A. Begin, K. Kokurewicz, C. Bowden, and P. A. Horgen. 1994. Inheritance of strain instability (sectoring) in the commercial button mushroom, Agaricus bisporus. Appl. Environ. Microbiol. 60:2384-2388.
19. Lindroth, M., P. B. Bell, Jr., and B-A. Fredricksson. 1988. Comparison of the effects of critical point-drying and freeze-drying on cytoskeletons and microtubules. J. Microsc. 151:103-114.
20. Maramatsu, M. 1973. Preparation of RNA from animal cells. Methods Cell Biol. 7:23-51.
21. Mims, C. W. 1981. Scanning electron microscopy (SEM) of aeciospore formation in Puccinia bolleyana. Scanning Electron Microsc. 1981:299-303.
22. Mims, C. W. 1991. Using electron microscopy to study plant pathogenic fungi. Mycologia 83:1-19.
23. Mims, C. W., E. A. Richardson, and W. E. Timberlake. 1988. Ultrastructural analysis of conidiophore development in the fungus Aspergillus nidulans using freeze-substitution. Protoplasma 144:132-141.
24. Prade, R. A., and W. E. Timberlake. 1993. The Aspergillus nidulans brlA regulatory locus consists of overlapping transcription units that are individually required for conidiophore development. EMBO J. 12:2439-2447.
25. Timberlake, W. E. 1990. Molecular genetics of Aspergillus development. Annu. Rev. Genet. 24:5-36.
26. Trail, F., P.-K. Chang, J. Cary, and J. E. Linz. 1994. Structural and functional analysis of the nor-1 gene involved in the biosynthesis of aflatoxins by Aspergillus parasiticus. Appl. Environ. Microbiol. 60:4078-4085.
27. Turner, W. B., and D. C. Aldridge. 1983. Fungal metabolites II. Academic Press Ltd., London.
28. Walker, R. C. (ed.). 1983. Official methods and recommended practices of the American Oil Chemists' Society. American Oil Chemists' Society, Champaign, Ill.
29. Wingfield, M. J. 1985. Reclassification of Verticicladiella based on conidial development. Trans. Br. Mycol. Soc. 85:81-93.
30. Woloshuk, C. P., K. R. Foutz, J. F. Brewer, D. Bhatnagar, T. E. Cleveland, and G. A. Payne. 1994. Molecular characterization of aflR, a regulatory locus for aflatoxin biosynthesis. Appl. Environ. Microbiol. 60:2408-2414.
31. Yu, J., J. W. Cary, D. Bhatnagar, T. E. Cleveland, N. P. Keller, and F. S. Chu. 1993. Cloning and characterization of a cDNA from Aspergillus parasiticus encoding an O-methyltransferase involved in aflatoxin biosynthesis. Appl. Environ. Microbiol. 59:3564-3571.