A soluble deletion mutant of the human complement receptor type 1, which lacks the C4b binding site, is a selective inhibitor of the alternative complement pathway

European Journal of Immunology

Volumn 26, Issue 8, 1996, Pages 1729-1735

  Scesney, Susanne M ^a   Makrides, Savvas C ^a   Gosselin, Michael L ^a   Ford, Pamella J ^a   Andrews, Beth M ^a   Hayman, Edward G ^a   Marsh Jr , Henry C ^a  

^a T Cell Sciences Inc   (United States)

Author keywords

Alternative complement pathway; Complement inhibitor; CR1

Indexed keywords

ANAPHYLATOXIN; COMPLEMENT COMPONENT C3B; COMPLEMENT COMPONENT C3B RECEPTOR; COMPLEMENT COMPONENT C4B; COMPLEMENT RECEPTOR;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; COMPLEMENT ALTERNATIVE PATHWAY; COMPLEMENT INHIBITION; CONSENSUS SEQUENCE; DELETION MUTANT; HEMOLYSIS; HUMAN; NONHUMAN; PRIORITY JOURNAL;

EID: 0029812624     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.1830260810     Document Type: Article

References (34)

1. Klickstein, L. B., Wong, W. W., Smith, J. A., Weis, J. H., Wilson, J. G. and Fearon, D. T., J. Exp. Med. 1987. 165: 1095.
2. Klickstein, L. L., Bartow, T. J., Miletic, V., Rabson, L. D., Smith, J. A. and Fearon, D. T., J. Exp. Med. 1988. 168: 1699.
3. Medved, L. V., Busby, T. F. and Ingham, K. C., Biochemistry 1989. 28: 5408.
4. Barlow, P. N., Baron, M., Norman, D. G., Day, A. J., Willis, A. C., Sim, R. B. and Campbell, I. D., Biochemistry 1991. 30: 997.
5. Barlow, P. N., Norman, D. G., Steinkasserer, A., Horne, T. J., Pearce, J., Driscoll, P. C., Sim, R. B. and Campbell, I. D., Biochemistry 1992. 31: 3626.
6. Norman, D. G., Barlow, P. N., Baron, M., Day, A. J., Sim, R. B. and Campbell, I. D., J. Mol. Biol. 1991. 219: 717.
7. Krych, M. K., Hourcade, D. and Atkinson, J. P., Proc. Natl. Acad. Sci. USA 1991. 88: 4353.
8. Kalli, K. R., Hsu, P., Bartow, T. J., Ahearn, J. M., Matsumoto, A. K., Klickstein, L. B. and Fearon, D. T., J. Exp. Med. 1991. 174: 1451.
9. Makrides, S. C., Scesney, S. M., Ford, P. J., Evans, K. S., Carson, G. R. and Marsh, H. C., J. Biol. Chem. 1992. 267: 24754.
10. Reilly, B. D., Makrides, S. C., Ford, P. J., Marsh, H. C. and Mold, C., J. Biol. Chem. 1994. 269: 7696.
11. Weisman, H. F., Bartow, T., Leppo, M. K., Marsh, H. C., Carson, G. R., Concino, M. F., Boyle, M. P., Roux, K. H., Weisfeldt, M. L. and Fearon, D. T., Science 1990. 249: 146.
12. Hammer, C. H., Wirtz, G. H., Renfer, L., Gresham, H. D. and Tack, B. F., J. Biol. Chem. 1981. 256: 3995.
13. Hammer, C. H. and Berger, M., in Rother, K. and Till, G. O. (Eds.) The Complement System, Springer-Verlag, Berlin and New York 1988, p. 17.
14. Tack, B. F. and Prahl, J. W., Biochemistry 1976. 15: 4512.
15. Tack, B. F., Hanatova, J., Thomas, M. L., Harrison, R. A. and Hammer, C. H., Methods Enzymol. 1981. 80: 64.
16. Bokisch, V. A., Müller-Eberhard, H. J. and Cochrane, C. G., J. Exp. Med. 1969. 129: 1109.
17. Law, S. K., Lichtenberg, N. A. and Levine, R. P., Proc. Natl. Acad. Sci. USA 1980. 77: 7194.
18. Carson, G. R., Kuestner, R. E., Ahmed, A., Pettey, C. L. and Concino, M. F., J. Biol. Chem. 1991. 266: 7883.
19. Wong, W. W., Jack, R. M., Smith, J. A., Kennedy, C. A. and Fearon, D. T., J. Immunol. Methods 1985. 82: 303.
20. Yeh, C. G., Marsh, H. C., Carson, G. R., Berman, L., Concino, M. F., Scesney, S. M., Kuestner, R. E., Skibbens, R., Donahue, K. A. and Ip, S. H., J. Immunol. 1991. 146: 250.
21. Platts-Mills, T. A. E. and Ishizaka, K., J. Immunol. 1974. 113: 348.
22. Wong, W. W. and Farrel, S. A., J. Immunol. 1991. 146: 656.
23. Chavez-Cartaya, R. E., Desola, G. P., Wright, L., Jamieson, N. V. and White, D. J. G., Transplantation 1995. 59: 1047.
24. Kaczorowski, S. L., Schiding, J. K., Toth, C. A. and Kochanek, P. M., J. Cereb. Blood Flow Metab. 1995. 15: 860.
25. Mulligan, M. S., Yeh, C. G., Rudolph, A. R. and Ward, P. A., J. Immunol. 1992. 148: 1479.
26. Piddlesden, S. J., Storch, M. K., Hibbs, M., Freeman, A. M., Lassmann, H. and Morgan, B. P., J. Immunol. 1994. 152: 5477.
27. Pruitt, S. K., Kirk, A. D., Bollinger, R. R., Marsh, H. C., Collins, B. H., Levin, J. L., Mault, J. R., Heinle, J. S., Ibrahim, S., Rudolph, A. R., Baldwin, W. M. and Sanfilippo, F., Transplantation 1994. 57: 363.
28. Himmelfarb, J., Mcmonagle, E., Holbrook, D. and Toth, C., J. Lab. Clin. Med. 1995. 126: 392.
29. Gillinov, A. M., DeValeria, P. A., Winkelstein, J. A., Wilson, I., Curtis, W. E., Shaw, D., Yeh, C. G., Rudolph, A. R., Baumgartner, W. A., Herskowitz, A. and Cameron, D. E., Ann. Thorac. Surg. 1993. 55: 619.
30. Murohara, T., Guo, J. P., Delyani, J. A. and Lefer, A. M., Methods Find. Exp. Clin. Pharmacol. 1995. 17: 499.
31. Gralinski, M. R., Wiater, B. C., Assenmacher, A. N. and Lucchesi, B. R., Immunopharmacology, in press.
32. Moran, P., Beasley, H., Gorrell, A., Martin, E., Gribling, P., Fuchs, H., Gillett, N., Burton, L. E. and Caras, I. W., J. Immunol. 1992. 149: 1736.
33. Christiansen, D., Milland, J., Thorley, B. R., McKenzie, I. F. C. and Loveland, B. E., Eur. J. Immunol 1996. 26: 578.
34. Wang, Y., Rollins, S. A., Madri, J. A. and Matis, L. A., Proc. Natl. Acad. Sci. USA 1995. 92: 8955.