Proliferation of macrophage-lineage cells in the bone marrow, severe thymic atrophy, and extramedullary hematopoiesis of possible donor origin in an autopsy case of post-transplantation graft-versus-host disease

Bone Marrow Transplantation

Volumn 18, Issue 2, 1996, Pages 437-441

  Kazama, T ^a   Miyazawa, M ^a,c   Tsuchiya, S ^b   Horii, A ^a  

^a TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

^c KINKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Bone marrow; Graft versus host disease; Macrophage; Microsatellite markers; Thymic atrophy

Indexed keywords

CYCLOPHOSPHAMIDE; CYCLOSPORIN; PREDNISOLONE;

ALLOGENIC BONE MARROW TRANSPLANTATION; APLASTIC ANEMIA; ARTICLE; AUTOPSY; BONE MARROW; CASE REPORT; CELL PROLIFERATION; DEATH; EPITHELIUM CELL; EXTRAMEDULLARY HEMATOPOIESIS; GRAFT VERSUS HOST REACTION; HEMATOPOIETIC CELL; HLA MATCHING; HUMAN; HUMAN CELL; HUMAN TISSUE; INTRAVENOUS DRUG ADMINISTRATION; MACROPHAGE; MALE; MULTIPLE ORGAN FAILURE; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; SCHOOL CHILD; SPLEEN CELL; T LYMPHOCYTE; THYMUS ATROPHY;

ATROPHY; AUTOPSY; BONE MARROW; BONE MARROW TRANSPLANTATION; CELL DIVISION; CHILD; DNA; GRAFT VS HOST DISEASE; HEMATOPOIESIS; HUMANS; MACROPHAGES; MALE; THYMUS GLAND; TRANSPLANTATION, HOMOLOGOUS;

EID: 0029812566     PISSN: 02683369     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Hows J, Palmer S, Gordon-Smith EC. Cyclosporin and graft failure following bone marrow transplantation for severe aplastic anemia. Br J Haematol 1985; 60: 611-617.
2. Atkinson K. Reconstruction of the hematopoietic and immune systems after marrow transplantation. Bone Marrow Transplant 1990; 5: 209-226.
3. Atkinson K, Dodds A, Concannon A, Biggs JC. Late onset transfusion-dependent anemia with thrombocytopenia secondary to marrow fibrosis and hypoplasia associated with chronic graft-versus-host disease. Bone Marrow Transplant 1987; 2: 445-449.
4. Dilly SA, Jagger CJ, Sloane JP. Stromal cell proliferation in necropsy bone marrow sections from allogeneic marrow recipients and non-transplant patients. J Clin Pathol 1993; 46: 611-616.
5. Iwasaki Y, Sako K, Ohara Y et al. Subacute panencephalitis associated with chronic graft-versus-host disease. Acta Neuropathol 1993; 85: 566-572.
6. Minegishi N, Minegishi M, Tsuchiya S, Konno T. Preservation of immature hematopoietic progenitor cells responding to interleukin 3 in marrow treated with 4-hydroxycyclophosphamide. Tohoku J Exp Med 1989; 159: 113-122.
7. Horii A, Han H-J, Shimada M et al. Frequent replication errors at microsatellite loci in tumors of patients with multiple primary cancers. Cancer Res 1994; 54: 3373-3375.
8. Jones MH, Yamakawa K, Nakamura Y. Isolation and characterization of 19 dinucleotide repeat polymorphism on chromosome 3p. Hum Mol Genet 1992; 1: 131-133.
9. Gyapay G, Morrissette J, Vignal A et al. The 1993-1994 Geneton human genetic linkage map. Nat Genet 1993; 7: 246-339.
10. Jones MH, Nakamura Y. Detection of loss of heterozygosity at the human TP53 locus using a dinucleotide repeat polymorphism. Genes Chromosome Cancer 1992; 5: 89-90.
11. Nezelof C. Thymic pathology in primary and secondary immunodeficiencies. Histopathology 1992; 21: 499-511.
12. Mangan KF, Chikkappa G, Bieler LZ et al. Regulation of human blood erythroid burst-forming unit (BFU-E) proliferation by T-lymphocyte subpopulations defined by Fc receptors and monoclonal antibodies. Blood 1982; 59: 990-996.