Hepatocyte growth factor induces tyrosine phosphorylation of focal adhesion kinase (FAK) and paxillin and enhances cell-matrix interactions

Oncology Reports

Volumn 3, Issue 5, 1996, Pages 819-823

  Jiang, W G ^a   Hiscox, S ^a   Nakamura, T ^b   Hallett, M B ^a   Puntis, M C A ^a   Mansel, R E ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

cell matrix adhesion; focal adhesion kinase; hepatocyte growth factor scatter factor; paxillin; tyrosine phosphorylation

Indexed keywords

CYTOKINE; INTEGRIN; MATRIGEL; MONOCLONAL ANTIBODY; PROTEIN TYROSINE KINASE; SCATTER FACTOR;

ARTICLE; BREAST CANCER; CANCER CELL; CANCER CELL CULTURE; CELL ADHESION; CELL INTERACTION; COLON CANCER; CONTROLLED STUDY; ENZYME INDUCTION; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

EID: 0029811745     PISSN: 1021335X     EISSN: None     Source Type: Journal    
DOI: 10.3892/or.3.5.819     Document Type: Article

References (45)

1. Nakamura T, Nishizawa T, Hagiya M, Seki T, Shimonishi M, Sugimura A, Tashiro K, Shimizu S: Molecular cloning and expression of human hepatocyte growth factor. Nature 342: 440-443, 1989.
2. Stoker M and Gherardi E: Regulation of cell movement. Biochim Biophys Acta 1072: 81-102, 1991.
3. Weidner KM, Behrens J, Vandekerckhove J and Birchmeier W: Scatter factor: molecular characteristics and effect on the invasiveness of epithelial cells. J Cell Biol 111: 2097-2108, 1990.
4. Rosen E, Meromsky L, Setter E, Vinter DW and Goldberg ID: Smooth muscle-derived factor stimulates mobility of human tumor cells. Inv Metast 10: 49-64, 1990.
5. Hanks SK, Calalb MB, Harper MC, Patel SK: Focal adhesion protein-tyrosine kinase phosphorylated in response to cell attachment to fibronectin. Proc Natl Acad Sci USA 89: 8487-8491, 1992.
6. Schaller MD and Parsons JT: Focal adhesion kinase and associated proteins. Curr Opin Cell Biol 6: 705-710, 1994.
7. Richardson A and Parsons JT: Signal transduction through integrins: a central role for focal adhesion kinase? BioEssays 17: 229-236, 1995.
8. Plopper GE, McNamee HP, Dike LE, Bojanowski K and Ingber DE: Convergence of integrin and growth factor receptor signaling pathways within the focal adhesion complex. Mol Biol Cell 6: 1349-1365, 1995.
9. Arora PD, Ma J, Min W, Cruz T, McCulloch CAG: Interleukin-1 induced calcium flux in human fibroblasts is mediated through facal adhesions. J Biol Chem 270: 6042-6049, 1995.
10. Guinebault C, Payrastre B, Racaud-Sultan C, Mazarguil H, Breton M, Mauco G, Plantavid M and Chap H: Integrin dependent translocation of phosphoinositide 3-kinase to the cytoskeleton of thrombin activated platelets involves specific interation of p95α with actin filaments and focal adhesion kinase. J Cell Biol 129: 831-842, 1995.
11. Matsumoto K, Matsumoto K, Nakamura T, Kramer RH: Hepatocyte growth-factor scatter factor induces tyrosine phosphorylation of focal adhesion kinase (p125(FAK)) and promotes migration and invasion by oral squamous-cell carcinoma-cells. J Biol Chem 269: 31807-31813, 1994.
12. Rankin S, Morii N, Narumiya S, Rozengurt E: Botulinum C3 exoenzyme blocks the tyrosine phosphorylation of p125FAK and paxillin induced by bombesin and endothelin. FEBS Lett 354: 315-319, 1994.
13. Seufferlein T, Rozengurt E: Sphingosine induces p125FAK and paxillin tyrosine phosphorylation, actin stress fiber formation, and focal contact assembly in Swiss 3T3 cells. J Biol Chem 269: 27610-27617, 1994.
14. Higuchi O, Mizuno K, Vandewoude GF, Nakamura T: Expression of c-met protooncogene in cos cells induces the signal transducing high-affinity receptor for hepatocyte growth-factor. FEBS Lett 301: 282-286, 1992.
15. Roberts G: Characterization of the antigens recognised by 2 monoclonal antibodies reactive with basal layer of keratinocyte of human epidermis. Biochem J 299: 659-664, 1994.
16. Jiang WG, Hiscox S, Hallett MB, Scott C, Horrobin DF and Puntis MCA: Inhibition of hepatocyte growth factor/ scatter factor induced motility and invasion of human cancer cells by gamma linolenic acid. Br J Cancer 71: 744-752, 1995.
17. Hart IR, Goode NT and Wilson RE: Molecular aspects of the metastatic cascade. Biochim Biophys Acta 989: 675-84, 1989.
18. Jiang WG, Puntis MCA and Hallett MB: Molecular and cellular basis of cancer invasion and metastasis: implication for treatment. Br J Surg 81: 1576-1590, 1994.
19. Haas TA and Plow EF: Integrin-ligand interactions. Curr Opin Cell Biol 6: 656-662, 1994.
20. Jiang WG, Hallett MB and Puntis MCA: Hepatocyte growth factor/scatter factor, liver regeneration and cancer metastasis. Br J Surg 80: 1368-1373, 1993.
21. Stoker M, Gherardi E, Perryman M and Grey J: Scatter factor is a fibroblast-derived modulator of epithelial cell mobility. Nature 327: 239-242, 1987.
22. Shibamoto S, Hayakawa M and Hori T: Hepatocyte growth factor and transforming growth factor-β stimulates both cell growth and migration of human gastric adenocarcinoma cells. Cell Struc Funct 17: 185-190, 1992.
23. Bussolino F, Di Renzo MF, Ziche M, Bocchietto E, Olivero M, Naldini L, Gaudino G, Tamagonone L, Coffer A and Comoglio PW: Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth. J Cell Biol 119: 629-641, 1992.
24. Nagaike M, Hirao S, Tajima H, Noji S, Tamiguchi S, Matsumoto K and Nakamura T: Renotropic functions of hepatocyte growth factor in renal regeneration after unilateral nephrectomy. J Biol Chem 266: 22781-22784, 1991.
25. Comoglio PM, Di Renzo MF and Naldini L: Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial-cell motility and growth. J Cell Biochem S17A, 232, 1993.
26. Grant DS, Kleinman HK and Goldberg ID: Scatter factor induces blood-vessel formation in vivo. Proc Natl Acad Sci USA 90: 1937-1941, 1993.
27. Lindroos PM, Zarnegar R and Michalopoulos GK: Hepatocyte growth factor (hepatopoietin A) rapidly increases in plasma before DNA synthesis and liver regeneration stimulation by partial hepatectomy and carbon tetrachhloride administration. Hepatology 13: 743-749, 1991.
28. Gohda E, Tsubouchi H, Nakayama H, Hirono S, Sakiyama O, Takahasi K, Miyazaki H, Hiashimpto S and Daikuhara Y: Purification and partial characterization of hepatocyte growth factor from plasma of a patient with fulminant hepatic failure. J Clin Invest 81: 414-419, 1988.
29. Taniguchi T, Toi M, Inada K, Imazawa T, Yamamoto Y and Tominaga T: Serum concentrations of hepatocyte growth factor in breast cancer patients. Clin Cancer Res 1: 1031-1034, 1995.
30. Yamashita J, Ogawa M, Yamashita S, Nomura K, Kuramoto M, Saishoji T, Shin S: Immunoreactive hepatocyte growth factor is a strong and independent predictor of recurrence and survival in human breast cancer. Cancer Res 54: 1630-1633, 1994.
31. Di Renzo MF, Olivero M, Giacomini A, Porte H, Chastre E, Mirossay L, Nordlinger B, Bretti S, Bottardi S, Giordano S, Plebani M, Gespach C and Comoglio PM: Overexpression and amplification of the MET-HGF receptor gene during the progression of colorectal cancer. Clin Cancer Res 1: 147-154, 1995.
32. Hauptmann S, Denkert C, Lohrke H, Tietze L, Ott S, Klosterhalfen B, Mittermayer C: Integrin expression on colorectal tumor-cells growing as monolayers, as multicellular tumor spheroids, or in nude-mice. Int J Cancer 61: 819-825, 1995.
33. Vanwaes C, Surh DM, Chen Z, Kirby M, Rhim JS, Brager R: Increase in suprabasilar integrin adhesion molecule expression in human epidermal neoplasms accompanies increased proliferation occurring with immortalization and tumor. Cancer Res 55: 5434-5444, 1995.
34. Fujita S, Watanabe M, Kubota T, Teramoto T, Kitajima M: Alteration of expression in integrin beta(1)-subunit correlates with invasion and metastasis in colorectal-cancer. Cancer Lett 91: 145-149, 1995.
35. Lessey BS, Albelda S, Buck CS, Castelbaum AJ, Yeh IT, Kohler M, Berchuck A: Distribution of integrin cell-adhesion molecules in endometrial cancer. Am J Pathol 146: 717-726, 1995.
36. Volberg T, Geiger B, Kam Z, Pankov R, Simcha I, Sabanay H, Coll JL, Adamson E, Benzeev A: Focal adhesion formation by f9 embryonal carcinoma-cells after vinculin gene disruption. J Cell Sci 108: 2253-2260, 1995.
37. Glukhova M, Koteliansky V, Sastre X, Thiery JP: Adhesion systems in normal breast and in invasive breast carcinoma. Am J Pathol 146: 706-716, 1995.
38. Owens LV, Xu LH, Craven RJ, Dent GA, Weiner TM, Kornberg L, Liu ET, Cance WG: Overexpression of the focal adhesion kinase (p125(fak)) in invasive human tumors. Cancer Res 55: 2752-2755, 1995.
39. Weiner TM, Liu ET, Craven RJ, Cance WG: Expression of focal adhesion kinase gene and invasive cancer. Lancet 342: 1024-1025, 1993.
40. Salgia R, Brunkhorst B, Pisick E, Li JL, Lo SH, Chen LB, Griffin JD: Molecular cloning of human paxillin, a focal adhesion protein phosphorylated by P210BCR/ABL. Oncogene 11: 1149-1155, 1995.
41. Abedi H, Dawes KE, Zachary I: Differential-effects of platelet-derived growth-factor bb on p125 focal adhesion kinase and paxillin tyrosine phosphorylation and on cell-migration in rabbit aortic vascular smooth-muscle cells and swiss 3T3 fibroblasts. J Biol Chem 270: 11367-11376, 1995.
42. Knight JB, Yamauchi K, Pessin JE: Divergent insulin and platelet-derived growth factor regulation of focal adhesion kinase (pp125FAK) tyrosine phosphorylation, and rearrangement of actin stress fibers. J Biol Chem 270: 10199-10203, 1995.
43. Melamed I, Turner CE, Aktories K, Kaplan DR, Gelfand EW: Nerve growth-factor triggers microfilament assembly and paxillin phosphorylation in human B-lymphocytes. J Exp Med 181: 1071-1079, 1995.
44. Hatai M, Hashi H, Mogi A, Soga H, Yokota J, Yaoi Y: Stimulation of tyrosine-phosphorylation and serine-phosphorylation of focal adhesion kinase in mouse 3T3 cells by fibronectin and fibroblast growth-factor. FEBS Lett 350: 113-116, 1994.
45. Jiang WG, Hiscox S, Puntis MCA, Hallett MB, Bryce RP, Horrobin DF and Mansel RE: Gamma linolenic acid inhibits tyrosine phosphorylation of focal adhesion kinase and paxillin and tumour cell matrix interaction. Int J Oncol 8: 583-587, 1996.