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Volumn 12, Issue 4, 1996, Pages 343-351

Inhibition of HIV replication by sense and antisense Rev response elements in HIV-based retroviral vectors

Author keywords

Retroviral vectors; REV; Rev response element (RRE); TAT

Indexed keywords

STRUCTURAL PROTEIN; TRANSACTIVATOR PROTEIN; VIRUS VECTOR;

EID: 0029811723     PISSN: 10779450     EISSN: None     Source Type: Journal    
DOI: 10.1097/00042560-199608010-00003     Document Type: Article
Times cited : (19)

References (60)
  • 1
    • 0024414213 scopus 로고
    • HIV-1 Tat protein increases transcriptional initiation and stabilizes elongation
    • Laspia MF, Rice AP, Mathews MB. HIV-1 Tat protein increases transcriptional initiation and stabilizes elongation. Cell 1989;59:283-92.
    • (1989) Cell , vol.59 , pp. 283-292
    • Laspia, M.F.1    Rice, A.P.2    Mathews, M.B.3
  • 2
    • 0025333764 scopus 로고
    • Activation of transcription by HIV-1 Tat protein tethered to nascent RNA through another protein
    • Southgate C, Zapp ML, Green MR. Activation of transcription by HIV-1 Tat protein tethered to nascent RNA through another protein. Nature 1990;345:640-2.
    • (1990) Nature , vol.345 , pp. 640-642
    • Southgate, C.1    Zapp, M.L.2    Green, M.R.3
  • 3
    • 0026003370 scopus 로고
    • Transcriptional elongation purified RNA polymerase II is blocked at the trans-activation responsive region of human immunodeficiency virus type 1 in vitro
    • Bengal E, Aloni Y. Transcriptional elongation purified RNA polymerase II is blocked at the trans-activation responsive region of human immunodeficiency virus type 1 in vitro. J Virol 1991;65:4910-8.
    • (1991) J Virol , vol.65 , pp. 4910-4918
    • Bengal, E.1    Aloni, Y.2
  • 4
    • 0026064723 scopus 로고
    • HIV-1 Tat protein promotes formation of more-processive elongation complexes
    • Marciniak RA, Sharp PA. HIV-1 Tat protein promotes formation of more-processive elongation complexes. EMBO J 1991;10:4189-96.
    • (1991) EMBO J , vol.10 , pp. 4189-4196
    • Marciniak, R.A.1    Sharp, P.A.2
  • 5
    • 0022553463 scopus 로고
    • HTLV-III expression and production involve complex regulation at the levels of splicing and translation of viral RNA
    • Feinberg MB, Jarrett RF, Aldovini A, Gallo RC, Wong SF. HTLV-III expression and production involve complex regulation at the levels of splicing and translation of viral RNA. Cell 1986;46:807-17.
    • (1986) Cell , vol.46 , pp. 807-817
    • Feinberg, M.B.1    Jarrett, R.F.2    Aldovini, A.3    Gallo, R.C.4    Wong, S.F.5
  • 6
    • 0022444917 scopus 로고
    • A second post-transcriptional trans-activator gene required for HTLV-III replication
    • Sodroski J, Goh WC, Rosen C, Dayton A, Terwilliger E, Haseltine W. A second post-transcriptional trans-activator gene required for HTLV-III replication. Nature 1986;321: 412-7.
    • (1986) Nature , vol.321 , pp. 412-417
    • Sodroski, J.1    Goh, W.C.2    Rosen, C.3    Dayton, A.4    Terwilliger, E.5    Haseltine, W.6
  • 7
    • 0022470729 scopus 로고
    • The transactivation gene of HTLV-III is essential for virus replication
    • Fisher AG, Feinberg MB, Josephs SF, et al. The transactivation gene of HTLV-III is essential for virus replication. Nature 1986;320:367-71.
    • (1986) Nature , vol.320 , pp. 367-371
    • Fisher, A.G.1    Feinberg, M.B.2    Josephs, S.F.3
  • 9
    • 0023809170 scopus 로고
    • Immunodeficiency virus Rev trans-activator modulates the expression of the viral regulatory genes
    • Malim MH, Hauber J, Fenrick R, Cullen BR. Immunodeficiency virus Rev trans-activator modulates the expression of the viral regulatory genes. Nature 1988;335:181-3.
    • (1988) Nature , vol.335 , pp. 181-183
    • Malim, M.H.1    Hauber, J.2    Fenrick, R.3    Cullen, B.R.4
  • 10
    • 0024518918 scopus 로고
    • The HIV-1 Rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA
    • Malim MH, Hauber J, Le SY, Maizel JV, Cullen BR. The HIV-1 Rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA. Nature 1989;338:254-7.
    • (1989) Nature , vol.338 , pp. 254-257
    • Malim, M.H.1    Hauber, J.2    Le, S.Y.3    Maizel, J.V.4    Cullen, B.R.5
  • 11
    • 0024382709 scopus 로고
    • Functional dissection of the HIV-1 Rev trans-activator-derivation of a trans-dominant represser of Rev-function
    • Malim MH, Böhnlein S, Hauber J, Cullen BR. Functional dissection of the HIV-1 Rev trans-activator-derivation of a trans-dominant represser of Rev-function. Cell 1989;58:205-14.
    • (1989) Cell , vol.58 , pp. 205-214
    • Malim, M.H.1    Böhnlein, S.2    Hauber, J.3    Cullen, B.R.4
  • 12
    • 0025190644 scopus 로고
    • HIV-1 structural gene expression requires binding of the Rev trans-activator to its RNA target sequence
    • Malim MH, Tiley LS, McCarn DF, Rusche JR, Hauber J, Cullen BR. HIV-1 structural gene expression requires binding of the Rev trans-activator to its RNA target sequence. Cell 1990;60:675-83.
    • (1990) Cell , vol.60 , pp. 675-683
    • Malim, M.H.1    Tiley, L.S.2    McCarn, D.F.3    Rusche, J.R.4    Hauber, J.5    Cullen, B.R.6
  • 14
    • 0024846372 scopus 로고
    • Functional analysis of CAR, the target sequence for the Rev protein of HIV-1
    • Dayton ET, Powell DM, Dayton AI. Functional analysis of CAR, the target sequence for the Rev protein of HIV-1. Science 1989;246:1625-9.
    • (1989) Science , vol.246 , pp. 1625-1629
    • Dayton, E.T.1    Powell, D.M.2    Dayton, A.I.3
  • 15
    • 0026584750 scopus 로고
    • Extensive sequence-specific information throughout the CAR/RRE, the target sequence of the human immunodeficiency virus type 1 Rev protein
    • Dayton ET, Konings DA, Powell DM, et al. Extensive sequence-specific information throughout the CAR/RRE, the target sequence of the human immunodeficiency virus type 1 Rev protein. J Virol 1992;66:1139-51.
    • (1992) J Virol , vol.66 , pp. 1139-1151
    • Dayton, E.T.1    Konings, D.A.2    Powell, D.M.3
  • 16
    • 0027412456 scopus 로고
    • The RRE of human immunodeficiency virus type 1 contributes to cell-type-specific viral tropism
    • Dayton ET, Konings DA, Lim SY, et al. The RRE of human immunodeficiency virus type 1 contributes to cell-type-specific viral tropism. J Virol 1993;67:2871-8.
    • (1993) J Virol , vol.67 , pp. 2871-2878
    • Dayton, E.T.1    Konings, D.A.2    Lim, S.Y.3
  • 17
    • 0024310483 scopus 로고
    • Sequence-specific RNA binding by the HIV-1 Rev protein
    • Zapp ML, Green MR. Sequence-specific RNA binding by the HIV-1 Rev protein. Nature 1989;342:714-6.
    • (1989) Nature , vol.342 , pp. 714-716
    • Zapp, M.L.1    Green, M.R.2
  • 18
    • 0025917131 scopus 로고
    • Oligomerization and RNA binding domains of the type 1 human immunodeficiency virus Rev protein: A dual function for an arginine-rich binding motif
    • Zapp ML, Hope TJ, Parslow TG, Green MR. Oligomerization and RNA binding domains of the type 1 human immunodeficiency virus Rev protein: a dual function for an arginine-rich binding motif. Proc Natl Acad Sci USA 1991;88: 7734-8.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 7734-7738
    • Zapp, M.L.1    Hope, T.J.2    Parslow, T.G.3    Green, M.R.4
  • 19
    • 0024836618 scopus 로고
    • Specific binding of HIV-1 recombinant Rev protein to the Rev-responsive element in vitro
    • Daly TJ, Cook KS, Gray GS, Maione TE, Rusche JR. Specific binding of HIV-1 recombinant Rev protein to the Rev-responsive element in vitro. Nature 1989;342:816-9.
    • (1989) Nature , vol.342 , pp. 816-819
    • Daly, T.J.1    Cook, K.S.2    Gray, G.S.3    Maione, T.E.4    Rusche, J.R.5
  • 20
    • 0024853361 scopus 로고
    • Regulation by HIV Rev depends upon recognition of splice sites
    • Chang DD, Sharp PA. Regulation by HIV Rev depends upon recognition of splice sites. Cell 1989;59:789-95.
    • (1989) Cell , vol.59 , pp. 789-795
    • Chang, D.D.1    Sharp, P.A.2
  • 21
    • 0025017326 scopus 로고
    • Specific interaction of the human immunodeficiency virus Rev protein with a structured region in the env mRNA
    • Cochrane AW, Chen CH, Rosen CA. Specific interaction of the human immunodeficiency virus Rev protein with a structured region in the env mRNA. Proc Natl Acad Sci USA 1990;87:1198-202.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 1198-1202
    • Cochrane, A.W.1    Chen, C.H.2    Rosen, C.A.3
  • 22
    • 0026555177 scopus 로고
    • Distinct RNA sequences in the gag region of human immunodeficiency virus type 1 decrease RNA stability and inhibit expression in the absence of Rev protein
    • Schwartz S, Felber BK, Pavlakis GN. Distinct RNA sequences in the gag region of human immunodeficiency virus type 1 decrease RNA stability and inhibit expression in the absence of Rev protein. J Virol 1992;66:150-9.
    • (1992) J Virol , vol.66 , pp. 150-159
    • Schwartz, S.1    Felber, B.K.2    Pavlakis, G.N.3
  • 23
    • 0028222158 scopus 로고
    • Elements distinct from human immunodeficiency virus type 1 splice sites are responsible for the Rev dependence of env mRNA
    • Nasiolas G, Zolotukhin AS, Tabernero C, et al. Elements distinct from human immunodeficiency virus type 1 splice sites are responsible for the Rev dependence of env mRNA. J Virol 1994;68:2986-93.
    • (1994) J Virol , vol.68 , pp. 2986-2993
    • Nasiolas, G.1    Zolotukhin, A.S.2    Tabernero, C.3
  • 24
    • 0023235382 scopus 로고
    • Expression of the art/trs protein of HIV and study of its role in viral envelope synthesis
    • Knight DM, Flomerfelt FA, Ghrayeb J. Expression of the art/trs protein of HIV and study of its role in viral envelope synthesis. Science 1987;236:837-40.
    • (1987) Science , vol.236 , pp. 837-840
    • Knight, D.M.1    Flomerfelt, F.A.2    Ghrayeb, J.3
  • 25
    • 0025100771 scopus 로고
    • Secondary structure is the major determinant for interaction of HIV Rev protein with RNA
    • Olsen HS, Nelbock P, Cochrane AW, Rosen CA. Secondary structure is the major determinant for interaction of HIV Rev protein with RNA. Science 1990;247:845-8.
    • (1990) Science , vol.247 , pp. 845-848
    • Olsen, H.S.1    Nelbock, P.2    Cochrane, A.W.3    Rosen, C.A.4
  • 26
    • 0025951988 scopus 로고
    • Mutational analysis of the HIV-1 Rev protein and its target sequence, the Rev responsive element
    • Olsen HS, Beidas S, Dillon P, Rosen CA, Cochrane AW. Mutational analysis of the HIV-1 Rev protein and its target sequence, the Rev responsive element. J Acquir Immun Defic Syndr 1991;4:558-67.
    • (1991) J Acquir Immun Defic Syndr , vol.4 , pp. 558-567
    • Olsen, H.S.1    Beidas, S.2    Dillon, P.3    Rosen, C.A.4    Cochrane, A.W.5
  • 27
    • 0025029048 scopus 로고
    • Purification and characterization of recombinant Rev protein of human immunodeficiency virus type 1
    • Nalin CM, Purcell RD, Antelman D, et al. Purification and characterization of recombinant Rev protein of human immunodeficiency virus type 1. Proc Natl Acad Sci USA 1990; 87:7593-7.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 7593-7597
    • Nalin, C.M.1    Purcell, R.D.2    Antelman, D.3
  • 28
    • 0025818452 scopus 로고
    • HIV-1 structural gene expression requires the binding of multiple Rev monomers to the viral RRE: Implications for HIV-1 latency
    • Malim MH, Cullen BR. HIV-1 structural gene expression requires the binding of multiple Rev monomers to the viral RRE: implications for HIV-1 latency. Cell 1991;65:241-8.
    • (1991) Cell , vol.65 , pp. 241-248
    • Malim, M.H.1    Cullen, B.R.2
  • 29
    • 0025766815 scopus 로고
    • Mutational definition of the human immunodeficiency virus type 1 Rev activation domain
    • Malim MH, McCarn DF, Tiley LS, Cullen BR. Mutational definition of the human immunodeficiency virus type 1 Rev activation domain. J Virol 1991;65:4248-54.
    • (1991) J Virol , vol.65 , pp. 4248-4254
    • Malim, M.H.1    McCarn, D.F.2    Tiley, L.S.3    Cullen, B.R.4
  • 30
    • 0025260544 scopus 로고
    • Human immunodeficiency virus Rev protein recognizes a target sequence in Rev-responsive element RNA within the context of RNA secondary structure
    • Holland SM, Ahmad N, Maitra RK, Wingfield P, Venkatesan S. Human immunodeficiency virus Rev protein recognizes a target sequence in Rev-responsive element RNA within the context of RNA secondary structure. J Virol 1990;64:5966-75.
    • (1990) J Virol , vol.64 , pp. 5966-5975
    • Holland, S.M.1    Ahmad, N.2    Maitra, R.K.3    Wingfield, P.4    Venkatesan, S.5
  • 31
    • 0025074348 scopus 로고
    • Function of the human immunodeficiency virus types 1 and 2 Rev proteins is dependent on their ability to interact with a structured region present in env gene mRNA
    • Dillon PJ, Nelbock P, Perkins A, Rosen CA. Function of the human immunodeficiency virus types 1 and 2 Rev proteins is dependent on their ability to interact with a structured region present in env gene mRNA. J Virol 1990;64:4428-31.
    • (1990) J Virol , vol.64 , pp. 4428-4431
    • Dillon, P.J.1    Nelbock, P.2    Perkins, A.3    Rosen, C.A.4
  • 32
    • 0026808753 scopus 로고
    • In vivo binding of wild-type and mutant human immunodeficiency virus type 1 Rev proteins: Implications for function
    • Arrigo SJ, Heaphy S, Haines JK. In vivo binding of wild-type and mutant human immunodeficiency virus type 1 Rev proteins: implications for function. J Virol 1992;66:5569-75.
    • (1992) J Virol , vol.66 , pp. 5569-5575
    • Arrigo, S.J.1    Heaphy, S.2    Haines, J.K.3
  • 33
    • 0025296036 scopus 로고
    • Structure-function analysis of the HTLV-I Rex and HIV-1 Rev RNA response elements: Insights into the mechanism of Rex and Rev function
    • Ahmed YF, Hanly SM, Malim MH, Cullen BR, Greene WC. Structure-function analysis of the HTLV-I Rex and HIV-1 Rev RNA response elements: insights into the mechanism of Rex and Rev function. Genes Dev 1990;4:1014-22.
    • (1990) Genes Dev , vol.4 , pp. 1014-1022
    • Ahmed, Y.F.1    Hanly, S.M.2    Malim, M.H.3    Cullen, B.R.4    Greene, W.C.5
  • 34
    • 0025251610 scopus 로고
    • Different sites of interaction for Rev, Tev, and Rex proteins within the Rev-responsive element of human immunodeficiency virus type 1
    • Solomin L, Felber BK, Pavlakis GN. Different sites of interaction for Rev, Tev, and Rex proteins within the Rev-responsive element of human immunodeficiency virus type 1. J Virol 1990;64:6010-7.
    • (1990) J Virol , vol.64 , pp. 6010-6017
    • Solomin, L.1    Felber, B.K.2    Pavlakis, G.N.3
  • 35
    • 0025819457 scopus 로고
    • Identification and characterization of a nuclear factor that specifically binds to the Rev response element (RRE) of human immunodeficiency virus type 1 (HIV-1)
    • Vaishnav YN, Vaishnav M, Wong-Staal F. Identification and characterization of a nuclear factor that specifically binds to the Rev response element (RRE) of human immunodeficiency virus type 1 (HIV-1). New Biol 1991;3:142-50.
    • (1991) New Biol , vol.3 , pp. 142-150
    • Vaishnav, Y.N.1    Vaishnav, M.2    Wong-Staal, F.3
  • 36
    • 0028265296 scopus 로고
    • Human immunodeficiency virus type 1 Rev-responsive element RNA binds to host cell-specific proteins
    • Shukla RR, Kimmel PL, Kumar A. Human immunodeficiency virus type 1 Rev-responsive element RNA binds to host cell-specific proteins. J Virol 1994;68:2224-9.
    • (1994) J Virol , vol.68 , pp. 2224-2229
    • Shukla, R.R.1    Kimmel, P.L.2    Kumar, A.3
  • 37
    • 0026848308 scopus 로고
    • Expression of chimeric neo-Rev response element sequences interferes with Rev-dependent HIV-1 gag expression
    • Zimmermann K, Weber S, Dobrovnik M, Hauber J, Böhnlein E. Expression of chimeric neo-Rev response element sequences interferes with Rev-dependent HIV-1 gag expression. Hum Gene Ther 1992;3:155-61.
    • (1992) Hum Gene Ther , vol.3 , pp. 155-161
    • Zimmermann, K.1    Weber, S.2    Dobrovnik, M.3    Hauber, J.4    Böhnlein, E.5
  • 38
    • 0025188193 scopus 로고
    • Overexpression of TAR sequences renders cells resistant to human immunodeficiency virus replication
    • Sullenger BA, Gallardo HF, Ungers GE, Gilboa E. Overexpression of TAR sequences renders cells resistant to human immunodeficiency virus replication. Cell 1990;63:601-8.
    • (1990) Cell , vol.63 , pp. 601-608
    • Sullenger, B.A.1    Gallardo, H.F.2    Ungers, G.E.3    Gilboa, E.4
  • 39
    • 0025837282 scopus 로고
    • Analysis of trans-acting response decoy RNA-mediated inhibition of human immunodeficiency virus type 1 transactivation
    • Sullenger BA, Gallardo HF, Ungers GE, Gilboa E. Analysis of trans-acting response decoy RNA-mediated inhibition of human immunodeficiency virus type 1 transactivation. J Virol 1991;65:6811-6.
    • (1991) J Virol , vol.65 , pp. 6811-6816
    • Sullenger, B.A.1    Gallardo, H.F.2    Ungers, G.E.3    Gilboa, E.4
  • 40
    • 0027198459 scopus 로고
    • Inhibition of human immunodeficiency virus type 1 replication by regulated expression of a polymeric Tat activation response RNA decoy as a strategy for gene-therapy in AIDS
    • Lisziewicz J, Sun D, Smythe J, et al. Inhibition of human immunodeficiency virus type 1 replication by regulated expression of a polymeric Tat activation response RNA decoy as a strategy for gene-therapy in AIDS. Proc Natl Acad Sci USA 1993;90:8000-4.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 8000-8004
    • Lisziewicz, J.1    Sun, D.2    Smythe, J.3
  • 41
    • 0025073956 scopus 로고
    • Inhibition of human immunodeficiency virus replication in cell culture by endogenously synthesized antisense RNA
    • Rhodes A, James W. Inhibition of human immunodeficiency virus replication in cell culture by endogenously synthesized antisense RNA. J Gen Virol 1990;71:1965-74.
    • (1990) J Gen Virol , vol.71 , pp. 1965-1974
    • Rhodes, A.1    James, W.2
  • 42
    • 0024747130 scopus 로고
    • Comparative analysis of the HTLV-1 Rex and HIV-1 Rev trans-regulatory proteins and their RNA response elements
    • Hanly SM, Rimsky LT, Malim MH, et al. Comparative analysis of the HTLV-1 Rex and HIV-1 Rev trans-regulatory proteins and their RNA response elements. Genes Dev 1989; 3:1534-44.
    • (1989) Genes Dev , vol.3 , pp. 1534-1544
    • Hanly, S.M.1    Rimsky, L.T.2    Malim, M.H.3
  • 43
    • 0024437549 scopus 로고
    • Trans-dominant inactivation of HTLV-1 and HIV-1 gene expression by mutation of the HTLV-I Rex transactivator
    • Rimsky L, Due Dodon M, Dixon EP, Greene WC. Trans-dominant inactivation of HTLV-1 and HIV-1 gene expression by mutation of the HTLV-I Rex transactivator. Nature 1989;341:453-6.
    • (1989) Nature , vol.341 , pp. 453-456
    • Rimsky, L.1    Due Dodon, M.2    Dixon, E.P.3    Greene, W.C.4
  • 44
    • 0021912920 scopus 로고
    • Complete nucleotide sequence of the AIDS virus, HTLV-III
    • Ratner L, Haseltine W, Patarca R, et al. Complete nucleotide sequence of the AIDS virus, HTLV-III. Nature 1985; 313:277-84.
    • (1985) Nature , vol.313 , pp. 277-284
    • Ratner, L.1    Haseltine, W.2    Patarca, R.3
  • 47
    • 0023625290 scopus 로고
    • Antisense RNA inhibition of endogenous genes
    • Stout JT, Caskey CT. Antisense RNA inhibition of endogenous genes. Methods Enzymol 1987;151:519-30.
    • (1987) Methods Enzymol , vol.151 , pp. 519-530
    • Stout, J.T.1    Caskey, C.T.2
  • 48
    • 0028054831 scopus 로고
    • Negative-strand RNA transcripts are produced in human immunodeficiency virus type 1-infected cells and patients by a novel promoter downregulated by Tat
    • Michael NL, Vahey MT, d'Arcy L, et al. Negative-strand RNA transcripts are produced in human immunodeficiency virus type 1-infected cells and patients by a novel promoter downregulated by Tat. J Virol 1994;68:979-87.
    • (1994) J Virol , vol.68 , pp. 979-987
    • Michael, N.L.1    Vahey, M.T.2    D'Arcy, L.3
  • 49
    • 0026003623 scopus 로고
    • Inhibition of human immunodeficiency virus type 1 replication in human T cells stably expressing antisense RNA
    • Sczakiel G, Pawlita M. Inhibition of human immunodeficiency virus type 1 replication in human T cells stably expressing antisense RNA. J Virol 1991;65:468-71.
    • (1991) J Virol , vol.65 , pp. 468-471
    • Sczakiel, G.1    Pawlita, M.2
  • 50
    • 0027326407 scopus 로고
    • Inhibition of HIV-1 replication by a high-copy-number vector expressing antisense RNA for reverse transcriptase
    • Meyer J, Nick S, Stamminger T, Grummt F, Jahn G, Lipps HJ. Inhibition of HIV-1 replication by a high-copy-number vector expressing antisense RNA for reverse transcriptase. Gene 1993;129:263-8.
    • (1993) Gene , vol.129 , pp. 263-268
    • Meyer, J.1    Nick, S.2    Stamminger, T.3    Grummt, F.4    Jahn, G.5    Lipps, H.J.6
  • 51
    • 0026785305 scopus 로고
    • Inhibition of replication of HIV-1 by retroviral vectors expressing tat-antisense and anti-tat ribozyme RNA
    • Lo KM, Biasolo MA, Dehni G, Palu G, Haseltine WA. Inhibition of replication of HIV-1 by retroviral vectors expressing tat-antisense and anti-tat ribozyme RNA. Virology 1992;190:176-83.
    • (1992) Virology , vol.190 , pp. 176-183
    • Lo, K.M.1    Biasolo, M.A.2    Dehni, G.3    Palu, G.4    Haseltine, W.A.5
  • 52
    • 0026806356 scopus 로고
    • Tat- and Rev-directed antisense RNA expression inhibits and abolishes replication of human immunodeficiency virus type 1: A temporal analysis
    • Sczakiel G, Oppenlander M, Rittner K, Pawlita M. Tat- and Rev-directed antisense RNA expression inhibits and abolishes replication of human immunodeficiency virus type 1: a temporal analysis. J Virol 1992;5576-81.
    • (1992) J Virol , pp. 5576-5581
    • Sczakiel, G.1    Oppenlander, M.2    Rittner, K.3    Pawlita, M.4
  • 53
    • 0026523627 scopus 로고
    • Ribozymes as anti-HIV-1 therapeutic agents: Principles, applications, and problems
    • Rossi JJ, Elkins D, Zaia JA, Sullivan S. Ribozymes as anti-HIV-1 therapeutic agents: principles, applications, and problems. Aids Res Hum Retroviruses 1992;8:183-9.
    • (1992) Aids Res Hum Retroviruses , vol.8 , pp. 183-189
    • Rossi, J.J.1    Elkins, D.2    Zaia, J.A.3    Sullivan, S.4
  • 54
    • 0026521479 scopus 로고
    • Overexpression of RRE-derived sequences inhibits HIV-1 replication in CEM cells
    • Lee TC, Sullenger BA, Gallardo HF, Ungers GE, Gilboa E. Overexpression of RRE-derived sequences inhibits HIV-1 replication in CEM cells. New Biol 1992;4:66-74.
    • (1992) New Biol , vol.4 , pp. 66-74
    • Lee, T.C.1    Sullenger, B.A.2    Gallardo, H.F.3    Ungers, G.E.4    Gilboa, E.5
  • 55
    • 0027289286 scopus 로고
    • Packaging of human immunodeficiency virus type 1 RNA requires cis-acting sequences outside the 5′ leader region
    • Richardson JH, Child LA, Lever AML. Packaging of human immunodeficiency virus type 1 RNA requires cis-acting sequences outside the 5′ leader region. J Virol 1993;67:3997-4005.
    • (1993) J Virol , vol.67 , pp. 3997-4005
    • Richardson, J.H.1    Child, L.A.2    Lever, A.M.L.3
  • 56
    • 0024320772 scopus 로고
    • Identification of a sequence required for efficient packaging of human immunodeficiency virus type 1 RNA into virions
    • Lever AML, Gottlinger H, Haseltine W, Sodroski J. Identification of a sequence required for efficient packaging of human immunodeficiency virus type 1 RNA into virions. J Virol 1989;63:4085-7.
    • (1989) J Virol , vol.63 , pp. 4085-4087
    • Lever, A.M.L.1    Gottlinger, H.2    Haseltine, W.3    Sodroski, J.4
  • 58
    • 0026051132 scopus 로고
    • Gene transfer into human lymphocytes by a defective human immunodeficiency virus type 1 vector
    • Poznansky M, Lever AM, Bergeron L, Haseltine W, Sodroski J. Gene transfer into human lymphocytes by a defective human immunodeficiency virus type 1 vector. J Virol 1991;65:532-6.
    • (1991) J Virol , vol.65 , pp. 532-536
    • Poznansky, M.1    Lever, A.M.2    Bergeron, L.3    Haseltine, W.4    Sodroski, J.5
  • 59
    • 0028067327 scopus 로고
    • A human immunodeficiency virus type 1 (HIV-1)-based retroviral vector system utilizing stable HIV-1 packaging cell lines
    • Carroll R, Lin J-T, Dacquel EJ, Mosca JD, Burke DS, St. Louis DC. A human immunodeficiency virus type 1 (HIV-1)-based retroviral vector system utilizing stable HIV-1 packaging cell lines. J Virol 1994;68:6047-51.
    • (1994) J Virol , vol.68 , pp. 6047-6051
    • Carroll, R.1    Lin, J.-T.2    Dacquel, E.J.3    Mosca, J.D.4    Burke, D.S.5    St6    Louis, D.C.7
  • 60
    • 0026521596 scopus 로고
    • Human immunodeficiency virus vectors for inducible expression of foreign genes
    • Buchschacher GL, Panganiban AT. Human immunodeficiency virus vectors for inducible expression of foreign genes. J Virol 1992;66:2731-9.
    • (1992) J Virol , vol.66 , pp. 2731-2739
    • Buchschacher, G.L.1    Panganiban, A.T.2


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