Angiogenesis as a new target for cancer treatment

Cancer Chemotherapy and Pharmacology, Supplement

Volumn 38, Issue , 1996, Pages

  Ono, Mayumi ^a   Izumi, Hiroto ^a   Yoshida, Shigeo ^a   Goto, Daisuke ^a   Jimi, Sei Ichiro ^a   Kawahara, Naoyuki ^a   Shono, Tadahisa ^a   Ushiro, Shin ^a   Ryuto, Masahiro ^a   Kohno, Kimitoshi ^a   Sato, Yasafumi ^b   Kuwano, Michihiko ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

Author keywords

Angiogenic factors; Antiangiogenic agents; Tumor angiogenesis; Vascular endothelial cells

Indexed keywords

ANGIOGENESIS INHIBITOR; ANGIOGENIC FACTOR; FUMAGILLIN; FUMAGILLOL CHLOROACETYLCARBAMATE; IRSOGLADINE MALEATE;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; CANCER THERAPY; CONFERENCE PAPER; CONTROLLED STUDY; DRUG DEVELOPMENT; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0029811670     PISSN: 09439404     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002800051044     Document Type: Conference Paper

References (38)

1. Abe T, Okamura K, Ono M, Kohno K, Mori T, Hori S, Kuwano M (1993) Induction of vascular endothelial tubular morphogenesis by human glioma cells. A model system for tumor angiogenesis. J Clin Invest 92: 54
2. Asano M, Yukita A, Matsumoto T, Kondo S, Suzuki H (1995) Inhibition of tumor growth and metastasis by an immunoneutralizing monoclonal antibody to human vascular endothelial growth factor/vascular permeability factor. Cancer Res 55: 5296
3. Bicknell R (1994) Vascular targeting and the inhibition of angiogenesis. Ann Oncol 4: 45
4. 3 for angiogenesis. Science 264: 569
5. 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell 79: 1157
6. Burrows FJ, Thorpe PE (1994) Vascular targeting: a new approach to the therapy of solid tumors. Pharmacol Ther 64: 155
7. Dameron KM, Volpert OV, Tainsky MA, Bouck N (1994) Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1. Science 265: 1582
8. Denekamp J, Hill S, Hobson B (1983) Vascular occlusion and tumor cell death. Eur J Cancer Clin Oncol 19: 271
9. Fidler IJ, Ellis LM (1994) The implications of angiogenesis for the biology and therapy of cancer metastasis. Cell 79: 185
10. Folkman J (1995) Angiogenesis in cancer, vascular, rheumatoid and other disease. Nature Med 41: 127
11. Folkman J, Klagsbrun M (1987) Vascular physiology. A family of angiogenic peptides. Nature 329: 671
12. Horak ER, Leek R, KIenk N, LeJeune S, Smith K, Stuart N, Greenall M, Stepniewska K, Harris AL (1992) Angiogenesis, assessed by platelet/endothelial cell adhesion molecule antibodies, as indicator of node metastases and survival in breast cancer. Lancet 340: 1120
13. Ingber D, Fujita T, Kishimoto S, Sudo K, Kanamaru T, Brem H, Folkman J (1990) Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth. Nature 348: 555
14. Inoguchi T, Ueda F, Umeda F, Yamashita T, Nawata H (1995) Inhibition of intercellular communication via gap junction in cultured aortic endothelial cells by elevated glucose and phorbol ester. Biochem Biophys Res Commun 208: 492
15. Ito K, Abe T, Tomita M, Morimoto A, Kohno K, Mori T, Ono M, Sugenoya A, Nishihira T, Kuwano M (1993) Anti-angiogenic activity of arachidonic acid metabolism inhibitors in angiogenesis model systems involving human microvascular endothelial cells and neovascularization in mice. Int J Cancer 55: 660
16. Karp JE, Broder S (1995) Molecular foundations of cancer: new targets for intervention. Nature Med 1: 309
17. Kim KJ, Li B, Winer J, Armanini M, Gillett N, Phillips HS, Ferrara N (1993) Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo. Nature 362: 841
18. Klagsbrun M, D'Amore PA (1991) Regulators of angiogenesis. Annu Rev Physiol 53: 217
19. Kusaka M, Sudo K, Fujita T, Marui S, Itoh F, Ingber D, Folkman J (1991) Potent anti-angiogenic action of AGM-1470: comparison to the fumagillin parent. Biochem Biophys Res Commun 174: 1070
20. Kuwano M, Ushiro S, Ryuto M, Samoto K, Izumi H, Ito K, Abe T, Nakamura T, Ono M, Kohno M (1994) Regulation of angiogenesis by growth factors. In: Nakamura T, Matsumoto K (eds) Growth factors in cell growth, morphogenesis and transformation. (Gann Monograph on Cancer Research 42) CRC, Boca Raton, Florida, p 13
21. Macchiarini P, Fontaini G, Hardin MJ, Chuanchieh H, Bigini D, Vignati S, Pingitore R, Angeletti CA (1992) Relation of neovasculature to metastasis of non-small-cell lung cancer. Lancet 340: 145
22. Mawatari M, Okamura K, Matsuda T, Hamanaka R, Mizoguchi H, Higashio K, Kohno K, Kuwano M (1991) Tumor necrosis factor and epidermal growth factor modulate migration of human microvascular endothelial cells and production of tissue-type plasminogen activator and its inhibitor. Exp Cell Res 192: 574
23. Morimoto A, Tada K, Nakayama Y, Kohno K, Naito S, Ono M, Kuwano M (1994) Cooperative roles of hepatocyte growth factor and plasminogen activator in tubular morphogenesis by human microvascular endothelial cells. Jpn J Cancer Res 85: 53-62
24. Okamura K, Morimoto A, Hamanaka R, Ono M, Kohno K, Uchida Y, Kuwano M (1992) A model system for tumor angiogenesis: involvement of transforming growth factor-alpha in tube formation of human microvascular endothelial cells induced by esophageal cancer cells. Biochem Biophys Res Commun 186: 1471
25. Ono M, Okamura K, Nakayama Y, Tomita M, Sato Y, Komatsu Y, Kuwano M (1992) Induction of human microvascular endothelial tubular morphogenesis by human keratinocytes: involvement of transforming growth factor-α. Biochem Biophys Res Commun 189: 601
26. Ono M, Kawahara N, Goto D, Wakabayashi Y, Ushiro S, Yoshida S, Izumi H, Kuwano M, Sato Y (1996) Inhibition of tumor growth and neovascularization by an anti-gastric ulcer agent. Cancer Res 56: 1512
27. O'Reilly MS, Holmgren L, Shing Y, Chen C, Rosenthal RA, Moses M, Lane WS, Cao Y, Sage EH, Folkman J (1994) Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma. Cell 79: 315
28. Rettig WJ, Garin-Chesa P, Healey JH, Su SL, Jaffe EA, Old LJ (1992) Identification of endosialin, a cell surface glycoprotein of vascular endothelial cells in human cancer. Proc Natl Acad Sci USA 89: 10832
29. Samoto K, Ikezaki K, Ono M, Shono T, Kohno K, Kuwano M, Fukui M (1995) Expression of vascular endothelial growth factor and its possible relation with neovascularization in human brain tumors. Cancer Res 55: 1189
30. Sato Y, Morimoto A, Kiue A, Okamura K, Hamanaka R, Kohno K, Kuwano M, Sakata T (1993) Irsogladine is a potent inhibitor of angiogenesis. FEBS Lett 322: 155
31. Sato Y, Okamura K, Morimoto A, Hamanaka R, Hamaguchi K, Shimada T, Ono M, Kohno K, Sakata T, Kuwano M (1993) Indispensable role of tissue-type plasminogen activator in growth factor-dependent tube formation of human microvascular endothelial cells in vitro. Exp Cell Res 204: 223
32. Srivastava A, Laidler P, Davies R, Morgan K, Hughes LE (1988) The prognostic significance of tumor vascularity in intermediate-thickness (0.76-4.0 mm thick) skin melanoma. Am J Pathol 133: 419
33. Tada K, Fukunaga T, Wakabayashi Y, Masumi S, Sato Y, Izumi H, Kohno K, Kuwano M (1994) Inhibition of tubular morphogenesis in human microvascular endothelial cells by co-culture with chondrocytes and involvement of transforming growth factor β: a model for avascularity in human cartilage. Biochim Biophys Acta 1201: 135
34. Taylor S, Folkman J (1982) Protamine is an inhibitor of angiogenesis. Nature 297: 307
35. Ueda F, Watanabe M, Hirata Y, Kyoi T, Kimura K (1991) Changes in cyclic AMP content of rat gastric mucosa induced by ulcerogenic stimuli in relation to the antiulcer activity of irsogladine maleate. Jpn J Pharmacol 55: 493
36. Wakabayashi M, Shono T, Isono M, Hori S, Matsushima K, Ono M, Kuwano M (1995) Dual pathways to tubular morphogenesis of vascular endothelial cells by human glioma cells: VEGF1/bFGF and IL-8. Jpn J Cancer Res 86: 1189
37. Weidner N, Semple JP, Welch WR, Folkman J (1991) Tumor angiogenesis and metastasis: correlation in invasive breast carcinoma. N Engl J Med 324: 1
38. Weidner N, Folkman J, Pozza F, Bevilacqua P, Allred EN, Moore DH, Meli S, Gasparini G (1992) Tumor angiogenesis: a new significant and independent prognostic indicator in early-stage breast carcinoma. J Natl Cancer Inst 84: 1875