Monoclonal antibody against lymphocyte function-associated antigen 1 inhibits the formation of primary biliary cirrhosis-like lesions induced by murine graft-versus-host reaction

Hepatology

Volumn 24, Issue 4 I, 1996, Pages 888-894

  Kimura, Takeshi ^a,b   Suzuki, Kenji ^a   Inada, Seisuke ^a   Hayashi, Akihiro ^a   Isobe, Mitsuaki ^c   Matsuzaki, Yasushi ^b   Tanaka, Naomi ^b   Osuga, Toshiaki ^b   Fujiwara, Michio ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b UNIVERSITY OF TSUKUBA   (Japan)

^c SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

INTERCELLULAR ADHESION MOLECULE 1; INTERCELLULAR ADHESION MOLECULE 1 ANTIBODY; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; MONOCLONAL ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ARTICLE; BILIARY CIRRHOSIS; GRAFT VERSUS HOST REACTION; IMMUNOPATHOGENESIS; IMMUNOTHERAPY; LYMPHOCYTIC INFILTRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SPLEEN LYMPHOCYTE; T LYMPHOCYTE; TREATMENT OUTCOME;

EID: 0029811525     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/jhep.1996.v24.pm0008855193     Document Type: Article

References (50)

1. Gorski A. The role of cell adhesion molecules in immunopathology. Immunol Today 1994;15:251-255.
2. Mackay CR, Imhof BA. Cell adhesion in the immune system. Immunol Today 1993;14:99-102.
3. van DJA, Horst E, Koopman G, Newmann W, Scheper RJ, Meijer CJ, Pals ST. The VLA-4/VCAM-1 pathway is involved in lymphocyte adhesion to endothelium in rheumatoid synovium. J Immunol 1991;147:4207-4210.
4. Wegner CD, Gundel RH, Reilly P, Haynes N, Letts LG, Rothlein R. Intercellular adhesion molecule-1 (ICAM-1) in the pathogenesis of asthma. Science 1990;247:456-459.
5. Malizia G, Calabrese A, Cottone M, Raimondo M, Trejdosiewicz LK, Smart CJ, Olivia L, et al. Expression of leukocyte adhesion molecules by mucosal mononuclear phagocytes in inflammatory bowel disease. Gastroenterology 1991;100:150-159.
6. Volpes R, van Oord JJ, Desmet VJ. Hepatic expression of intercellular adhesion molecule-1 (ICAM-1) in viral hepatitis B. HEPATOLOGY 1990;12: 148-154.
7. Garcia-Monzon C, Garcia-Buey L, Garcia-Sanchez A, Pajares J, Moreno-Otero R. Down-regulation of intercellular adhesion molecule 1 on hepatocytes in viral chronic hepatitis treated with interferon alfa-2b. Gastroenterology 1993;105:462-469.
8. Adams DH, Hubscher SG, Shaw J, Rothlein R, Neuberger JM. Intercellular adhesion molecule 1 on liver allografts during rejection. Lancet 1989; 2:1122-1125.
9. Adams DH, Hubscher SG, Shaw J, Johnson GD, Babbs C, Rothlein R, Neuberger JM. Increased expression of intercellular adhesion molecule 1 on bile ducts in primary biliary cirrhosis and primary sclerosing cholangitis. HEPATOLOGY 1991;14:426-431.
10. Volpes, R, van Oord JJ, Desmet VJ. Immunohistochemical study of adhesion molecules in liver inflammation. HEPATOLOGY 1990;12:59-65.
11. Cosimi AB, Conti D, Delmonico FL, Preffer FI, Wee SL, Rothlein R, Faanes R, et al. In vivo effects of monoclonal antibody to ICAM-1 (CD54) in nonhuman primates with renal allografts. J Immunol 1990;144:4604-4612.
12. Isobe M, Yagita H, Okumura K, Ihara A. Specific acceptance of cardiac allograft after treatment with antibodies to ICAM-1 and LFA-1. Science 1992;255:1125-1127.
13. Iigo Y, Takashi T, Tamatani T, Miyasaka M, Higashida T, Yagita H, Okumura K, et al. ICAM-1-dependent pathway is critically involved in the pathogenesis of adjuvant arthritis in rats. J Immunol 1991;147:4167-4171.
14. Kawasaki K, Yaoita E, Yamamoto T, Tamatani T, Miyasaka M, Kihara I. Antibodies against intercellular adhesion molecule-1 and lymphocyte function-associated antigen-1 prevent glomerular injury in rat experimental crescentic glomerulonephritis. J Immunol 1993;150:1074-1083.
15. Nishikawa K, Guo YJ, Miyasaka M, Tamatani T, Collins AB, Sy MS, McCluskey RT, et al. Antibodies to intercellular adhesion molecule 1/lymphocyte function-associated antigen 1 prevent crescent formation in rat autoimmune glomerulonephritis. J Exp Med 1993;177:667-677.
16. Harning R, Pelletier J, Lubbe K, Takei F, Merluzzi VJ. Reduction in the severity of graft-versus-host disease and increased survival in allogeneic mice by treatment with monoclonal antibodies to cell adhesion antigens LFA-1 and MALA-2. Transplantation 1991;52:842-845.
17. Davis LS, Kavanaugh AF, Nichols LA, Lipsky PE. Induction of persistent T cell hyporesponsiveness in vivo by monoclonal antibody to ICAM-1 in patients with rheumatoid arthritis. J Immunol 1995;154:3525-3537.
18. Saitoh T, Fujiwara M, Nomoto M, Makino M, Watanabe H, Ishihara K, Kamimura T. Hepatic lesions induced by graft-versus-host reaction across MHC class II antigens: an implication for animal model of primary biliary cirrhosis. Clin Immunol Immunopathol 1988;49:166-172.
19. Saitoh T, Fujiwara M, Nomoto M, Kamimura T, Ishihara K, Asakura H. Histologic studies on the hepatic lesions induced by graft-versus-host reaction in MHC class II disparate hosts compared with primary biliary cirrhosis. Am J Pathol 1989;135:301-307.
20. + T cells in semiallogeneic hosts with MHC class II disparity. J Immunol 1990;145:3268-3275.
21. + T cells induce hepatic lesions resembling primary biliary cirrhosis in mice with graft-ver sus-host reactions due to major histocompatibility complex class II disparity. Clin Immunol Immunopathol 1991;59:449-461.
22. Van de Water J, Cooper A, Surh CD, Coppel R, Danner D, Ansari A, Dickson R, et al. Detection of autoantibodies to recombinant mitochondrial proteins in patients with primary biliary cirrhosis. N Engl J Med 1989; 320:1377-1380.
23. Nishimura T, Itoh T. Higher level expression of lymphocyte function-associated antigen-1 (LFA-1) on in vivo natural killer cells. Eur J Immunol 1988;18:2077-2080.
24. Sanches-Madrid F, Simon P, Thompson S, Springer TA. Mapping of antigenic and functional epitopes on the alpha- and beta-subunits of two related mouse glycoproteins involved in cell interactions, LFA-1 and Mac-1. J Exp Med 1983;158:586-602.
25. Prieto J, Takei F, Gendelman R, Christenson B, Biberfeld P, Patarroyo M. MALA-2, mouse homologue of human adhesion molecule ICAM-1 (CD54). Eur J Immunol 1989;19:1551-1557.
26. Gershwin ME, Mackey IR. Primary biliary cirrhosis: paradigm or paradox for autoimmunity. Gastroenterology 1991;100:822-833.
27. Shimizu Y, Newman W, Tanaka Y, Shaw S. Lymphocytes interactions with endothelial cells. Immunol Today 1992;13:106-112.
28. Shimizu Y, Newman W, Gopal TV, Horgan KJ, Graber N, Beall LD, van SG. Four molecular pathways of T cell adhesion to endothelial cells: roles of LFA-1, VCAM-1, and ELAM-1 and changes in pathway hierarchy under different activation conditions. J Cell Biol 1991;113:1203-1212.
29. Kavanaugh AF, Lightfoot E, Lipsky PE, Oppenheimer MN. Role of CD11/ CD18 in adhesion and transendothelial migration of T cells. Analysis utilizing CD18-deficient T cell clones. J Immunol 1991;146:4149-4156.
30. Springer, TA. Adhesion receptors of the immune system. Nature 1990; 346:425-434.
31. Malrin SD, Springer TA. Purified intercellular adhesion molecule-1 (ICAM-1) is a ligand for lymphocyte function-associated antigen 1 (LFA-1) Cell 1987;51:813-819.
32. Staunton DE, Dustin ML, Springer TA. Functional cloning of ICAM-2, a cell adhesion ligand for LFA-1 homologous to ICAM-1. Nature 1989;339: 61-64.
33. de Fougerolles AR, Springer TA. Intercellular adhesion molecule 3, a third adhesion counter-receptor for lymphocyte function-associated molecule 1 on resting lymphocytes. J Exp Med 1992;175:185-190.
34. Dustin ML, Rothlein R, Bhan AK, Dinarello CA, Springer TA. Induction by IL-1 and interferon-γ: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1). J Immunol 1986;137:245-254.
35. Nortamo P, Li R, Renkonen R, Timonen T, Prieto J, Patarroyo M, Gahmberg CG. The expression of human intercellular adhesion molecule-2 is refractory to inflammatory cytokines. Eur J Immunol 1991;21:2629-2632.
36. Mueller D, Jenkins M, Schwarts RH. Clonal expansion versus functional clonal inactivation: a costimulatory outcome of T cell antigen receptor occupancy. In: Paul WE, ed. Annu Rev Immunol. Vol 7. Palo Alto: Annual Reviews, Inc., 1989:445-480.
37. Volpes R, van den Oord JJ, Desmet VJ. Vascular adhesion molecules in acute and chronic liver inflammation. HEPATOLOGY 1991;15:269-275.
38. Volpes R, van den Oord JJ, Desmet VJ. Distribution of the VLA family of integrins in normal and pathological human liver tissue. Gastroenterology 1991;101:200-206.
39. Gleichmann E, Pals ST, Rolink AG, Radaszkiewicz T, Gleichmann H. Graft-versus-host reactions: clues to the etiopathology of a spectrum of immunological diseases. Immunol Today 1984;5:324-332.
40. Scheynius A, Camp RL, Pure E. Reduced contact sensitivity reaction in mice treated with monoclonal antibodies to leukocyte function-associated molecule-1 and intercellular adhesion molecule-1. J Immunol 1993;150: 655-663.
41. Duijvestijn A, Hamann A. Mechanisms and regulation of lymphocyte migration. Immunol Today 1989;10:23-28.
42. Williams IR, Kupper TS. Epidermal expression of intercellular adhesion molecule 1 is not a primary inducer of cutaneous inflammation in transgenic mice. Proc Natl Acad Sci U S A 1994;91:9710-9714.
43. Fawcett J, Holness CL, Needham LA, Turley H, Gatter KC, Mason DY, Simmons DL. Molecular cloning of ICAM-3, a third ligand for LFA-1, constitutively expressed on resting leukocytes. Nature 1992;360:481-484.
44. Huang C, Springer TA. A binding interface on the I domain of lymphocyte function-associated antigen-1 (LFA-1) required for specific interaction with intercellular adhesion molecule 1 (ICAM-1). J Biol Chem 1995;270: 19008-19016.
45. Fischer A, Friedrich W, Fasth A, Blanche S, Le DF, Girault D, Veber F, et al. Reduction of graft failure by a monoclonal antibody (anti-LFA-1 CD11a) after HLA nonidentical bone marrow transplantation in children with immunodeficiencies, osteopetrosis, and Fanconi's anemia: a European group for immunodeficiency European group for bone marrow transplantation report. Blood 1991;77:249-256.
46. Gotoh M, Fukuzaki T, Monden M, Dono K, Kanai T, Yagita H, Okumura K, et al. A potential immunosuppressive effect of anti-lymphocyte function associated antigen-1 monoclonal antibody on islet transplantation. Transplantation 1994;57:123-126.
47. Shiohara T, Moriya N, Gotoh C, Saizawa K, Nagashima M. Locally administered monoclonal antibodies to lymphocyte function-associated antigen. 1 and to L3T4 prevent cutaneous graft-vs-host disease. J Immunol 1988; 141:2261-2267.
48. + T cells. J Exp Med 1991;173:759-762.
49. Liu Y, Jones B, Brady W, Janeway CA, Linsky PS. Co-stimulation of murine CD4 T cell growth: cooperation between B7 and heat stable antigen. Eur J Immunol 1992;22:2855-2859.
50. Banchereau J, Bazan F, Blanchard D, Briere F, Galizzi JP, Kooten CV, Liu YJ, et al. The CD40 antigen and its ligand. In: Paul WE, ed. Annu Rev Immunol. Vol 12, Palo Alto: Annual Reviews Inc., 1994:881-922.