A novel S phase inhibitor in fission yeast

EMBO Journal

Volumn 15, Issue 17, 1996, Pages 4603-4612

  Woollard, Alison ^a   Basi, Gabriele ^b   Nurse, Paul ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Cell cycle; Fission yeast; p34(cdc2); S phase; Schizosaccharomyces pombe

Indexed keywords

ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; GENE DELETION; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; YEAST;

EID: 0029811435     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1996.tb00838.x     Document Type: Article

References (46)

1. Buck, V., Russell, P. and Millar, J.B.A. (1995) Identification of a CDK-activating kinase in fission yeast. EMBO J., 14, 6173-6183.
2. Carr, A.M. and Hoekstra, M.F. (1995) The cellular responses to DNA damage. Trends Cell Biol., 5, 32-40.
3. Coleman, T.R. and Dunphy, W.G. (1994) Cdc2 regulatory factors. Curr. Biol., 6, 877-882.
4. cdc2 mitotic kinase. Cell, 83, 1001-1009.
5. Damagnez, V., Makela, T.P. and Cottarel, G. (1995) Schizosaccharomyces pombe mop1-mcs2 is related to mammalian CAK. EMBO J., 14, 6164-6172.
6. Den-Haese, G.J., Walworth, N., Carr, A.M. and Gould, K.L. (1995) The wee1 protein kinase regulates T14 phosphorylation of fission yeast cdc2. Mol. Biol. Cell, 6, 371-385.
7. +. Cell, 50, 319-325.
8. Elledge, S.J. and Harper, J.W. (1994) Cdk inhibitors: on the threshold of checkpoints and development. Curr. Opin. Cell Biol., 6, 847-852.
9. Fantes, P. (1981) Isolation of cell size mutants of a fission yeast by a new selective method. J. Bacteriol., 146, 746-754.
10. 1 cyclins. EMBO J., 15, 850-860.
11. Forsburg, S. and Nurse, P. (1991) Cell cycle regulation in the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe. Annu. Rev. Cell Biol., 7, 227-256.
12. + protein kinase regulates entry into mitosis. Nature, 342, 39-45.
13. cdc2 function. EMBO J., 10, 3297-3309.
14. Gyuris, J., Golemis, E., Chertkov, H. and Brent, R. (1993) Cdi1, a human G1 and S phase protein phosphatase that associates with cdk2. Cell, 75, 791-803.
15. Harlow, E. and Lane, D. (1988) In Antibodies: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp. 310-311.
16. cdc2 tyrosine phosphorylation. EMBO J., 14, 2760-2771.
17. Hofmann, J.F.X. and Beach, D. (1994) cdt1 is an essential target of the Cdc10/Sct1 transcription factor: requirement for DNA replication and inhibition of mitosis. EMBO J., 13, 425-434.
18. Hoheisel, J.D., Maier, E., Mott, R., McCarthy, L., Grigoriev, A.V. and Schalkwyk, L.C. (1993) High-resolution cosmid and P1-maps spanning the 14MB genome of the fission yeast S.pombe. Cell, 73, 109-120.
19. + gene product couples S-phase to Start and mitosis. Cell, 74, 371-382.
20. Labib, K. and Nurse, P. (1993) Bring on the phosphatases. Curr. Biol., 3, 164-166.
21. +. Nature, 355, 449-452.
22. rum1 cdk inhibitor. EMBO J., 15, 839-849.
23. Maundrell, K. (1989) nmt1 of fission yeast: a highly transcribed gene completely repressed by thiamine. J. Biol. Chem., 265, 10857-10864.
24. Maundrell, K. (1993) Thiamine-repressible expression vectors pREP and pRIP for fission yeast. Gene, 123, 127-130.
25. + gene. Nature, 367, 236-242.
26. cdc2 protein kinase during mitosis. Cell, 58, 361-372.
27. Moreno, S., Klar, A. and Nurse, P. (1991) Molecular genetic analysis of fission yeast Schizosaccharomyces pombe. Methods Enzymol., 194, 795-823.
28. Morgan, D.O. (1995) Principles of CDK regulation. Nature, 374, 131-134.
29. Nasmyth, K. (1993) Control of the yeast cell cycle by the CDC28 protein kinase. Curr. Biol., 5, 166-179.
30. Nigg, E.A. (1995) Cyclin-dependent protein kinases: key regulators of the eukaryotic cell cycle. BioEssays, 17, 471-480.
31. cdc18 plays a major role controlling the initiation of DNA replication in fission yeast. Cell, 83, 397-405.
32. Nurse, P. (1975) Genetic control of cell size at cell division in yeast. Nature, 256, 547-551.
33. Nurse, P. (1990) Universal control mechanism regulating onset of M-phase. Nature, 344, 503-508.
34. Nurse, P. and Bissett, Y. (1981) Gene required in G1 for commitment to cell cycle and in G2 for control of mitosis in fission yeast. Nature, 292, 558-560.
35. Obara-Ishihara, T. and Okayama, H. (1994) A B-type cyclin negatively regulates conjugation via interacting with cell cycle 'Start' genes in fission yeast. EMBO J., 13, 1863-1872.
36. Peter, M. and Herskowitz, I. (1994) Joining the complex: cyclin-dependent kinase inhibitory proteins and the cell cycle. Cell, 79, 181-184.
37. Pinna, L.A. (1990) Casein kinase 2: an 'eminence grise' in cellular regulation. Biochim. Biophys. Acta, 1054, 267-284.
38. Reed, S.I. and Wittenberg, C. (1990) Mitotic role for the Cdc28 protein kinase of Saccharomyces cerevisiae. Proc. Natl Acad. Sci. USA, 87, 5697-5701.
39. Rogers, S., Wells, R. and Rechsteiner, M. (1986) Amino-acid sequences common to rapidly degraded proteins: the PEST hypothesis. Science, 234, 364-368.
40. Sambrook, J., Fritsch, E. and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual, 2nd edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
41. Sazer, S. and Sherwood, S.W. (1990) Mitochondrial growth and DNA synthesis occur in the absence of nuclear DNA replication in fission yeast. J. Cell Sci., 97, 509-516.
42. Schwob, E., Bohm, T., Mendenhall, M.D. and Nasmyth, K. (1994) The B-type cyclin kinase inhibitor p40(SIC1) controls the G1 to S transition in Saccharomyces cerevisiae. Cell, 79, 233-244.
43. + of fission yeast encodes a protein kinase potentially regulated by phosphorylation. Cell, 45, 261-268.
44. + and swi4 gene products. EMBO J., 11, 4923-4932.
45. Woodgett, J.R., Gould, K.L. and Hunter, T. (1986) Substrate specificity of protein kinase C. Use of synthetic peptides corresponding to physiological sites as probes for substrate recognition requirements. Eur. J. Biochem., 161, 177-184.
46. Woollard, A. and Nurse, P. (1995) G1/S control and checkpoints operating around START in fission yeast. BioEssays, 17, 481-490.