An assessment of the routes of incorporation of opiates into beard hair after a single oral dose of codeine

Therapeutic Drug Monitoring

Volumn 18, Issue 6, 1996, Pages 724-728

  Callaghan, Robert R ^a   Wilson, John F ^a   Cartwright, Janice ^b  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b Cardiff Bioanalytical Services Ltd   (United Kingdom)

Author keywords

Codeine; Hair; Pharmacokinetics; Saliva; Sweat

Indexed keywords

CODEINE; COTININE;

ADULT; ARTICLE; DRUG DETERMINATION; DRUG DISTRIBUTION; DRUG MONITORING; DRUG SALIVA LEVEL; HAIR; HUMAN; MALE; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; SWEAT;

ADULT; CODEINE; HAIR; HUMANS; MALE; MIDDLE AGED; NARCOTICS; SALIVA; SWEAT;

EID: 0029811250     PISSN: 01634356     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007691-199612000-00017     Document Type: Article

References (25)

1. Baumgartner AM, Jones PF, Baumgartner WA, Black CT. Radioimmunoassay of hair for determining opiate-abuse histories. J Nucl Med 1979;20:748-52.
2. Valente D, Cassini M, Pigliapochi M, Vansetti G. Hair as the sample in assessing morphine and cocaine addiction. Clin Chem 1981;27:1952-3.
3. Moeller MR, Fey P, Sachs H. Hair analysis as evidence in forensic cases. Forensic Sci Int 1993;63:43-53.
4. Brewer C. Hair analysis for drugs of abuse. Lancet 1990;335:980.
5. Henderson GL. Mechanisms of drug incorporation into hair. Forensic Sci Int 1993;63:19-29.
6. Maurer HH, Fritz CF. Toxicological detection of pholcodine and its metabolites in urine and hair using radioimmunoassay, fluorescence polarisation immunoassay, enzyme immunoassay and gas chromatography-mass spectrometry. Int J Legal Med 1990;104: 43-6.
7. Kintz P, Tracqui A, Mangin P. Pharmacological studies on meprobamate incorporation in human beard hair. Int J Legal Med 1993; 105:283-7.
8. Gwent SH, Wilson JF, Tsanaclis LM, Wicks JFC. Time course of appearance of cotinine in human beard hair after a single dose of nicotine. Ther Drug Monit 1995;17:195-8.
9. Püschel K, Thomasch P, Arnold W. Opiate levels in hair. Forensic Sci Int 1983;21:181-6.
10. Cone EJ. Testing human hair for drugs of abuse. I. Individual dose and time profiles of morphine and codeine in plasma, saliva, urine, and beard compared to drug-induced effects on pupils and behavior. J Anal Toxicol 1990;14:1-7.
11. Nakahara Y, Takahashi K, Konuma K. Hair analysis for drugs of abuse. VI. The excretion of methoxyphenamine and methamphetamine into beards of human subjects. Forensic Sci Int 1993;63: 109-19.
12. Moeller MR, Mueller C. The detection of 6-monoacetylmorphine in urine, serum and hair by GC/MS and RIA. Forensic Sci Int 1995;70:125-33.
13. Spiehler V. The evidence for sweat as a mechanism for entry of drugs into hair. 2nd International Meeting on Clinical and Forensic Aspects of Hair Analysis, Genova, abstract, 1994:18.
14. Ritschel WA, Parab PV, Denson DD, Coyle DE, Gregg RV. Absolute bioavailability of hydromorphone after peroral and rectal administration in humans: saliva/plasma ratio and clinical effects. J Clin Pharmacol 1987;27:647-53.
15. Chen ZR, Bochner F, Smomgyi A. Pharmacokinetics of pholcodine in healthy volunteers: single and chronic dosing studies. Br J Clin Pharmacol 1988;26:445-53.
16. von Balabanova S, Schneider E, Wepler R, Hermann B, Boschek HJ, Scheitler H. Die Bedeutung der drogenbestimmung in pilocarpinschweiss für den nachweis eines zurückliegenden drogenkonsums. Beitr Gerichtl Med 1992;50:111-5.
17. Cone EJ, Hillsgrove MJ, Jenkins AJ, Keenan RM, Darwin WD. Sweat testing for heroin, cocaine, and metabolites. J Anal Toxicol 1994;18:298-305.
18. Kalasinsky KS, Magluilo J, Schaefer T. Study of drug distribution in hair by infrared microscopy visualization. J Anal Toxicol 1994; 18:337-41.
19. Welch MJ, Sniegoski LT, Allgood CC, Habram M. Hair analysis for drugs of abuse: evaluation of analytical methods, environmental issues, and development of reference materials. J Anal Toxicol 1993;17:389-98.
20. Hayashi S, Miyamoto I, Takeda K. Measurements of human hair growth by optical microscopy and image analysis. Br J Dermatol 1991;125:123-9.
21. Green SJ, Wilson JF. The effect of hair colour on the incorporation of methadone into hair in the rat. J Anal Toxicol 1996;20:121-3.
22. Vickers CFH. Existence of reservoir in the stratum corneum. Arch Dermatol 1963;88:20-3.
23. Holley FO, van Steennis C. Postoperative analgesia with fentanyl: pharmacokinetics and pharmacodynamics of constant-rate I.V. and transdermal delivery. Br J Anaesth 1988;60:608-13.
24. Ofori-Adjei D, Ericsson Ö. Chloroquine in nail clippings. Lancet 1985;ii:331.
25. Downing DT, Strauss JS, Ramasastry P, Abel M, Lees CW, Pochi PE. Measurement of the time between synthesis and surface excretion of sebaceous lipids in sheep and man. J Invest Dermatol 1975;64:215-9.