Increased estrogen receptor and epidermal growth factor receptor gene product co-expression in surgically resected gastric adenocarcinomas

Journal of Surgical Oncology

Volumn 63, Issue 3, 1996, Pages 166-171

  Koullias, George J ^a,d   Kouraklis, Gregorios P ^b   Raftopoulos, Ioannis S ^b   Davaris, Panagiotis S ^c   Papadopoulos, Stefanos Ap ^a   Golematis, Basil Ch ^a  

^a HIPPOKRATION HOSPITAL   (Greece)

^b IASO GENERAL HOSPITAL   (Greece)

^c UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^d New Rochelle Hospital Medical Center   (United States)

Author keywords

autocrine; growth factors; steroid receptors; stomach

Indexed keywords

EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; ESTROGEN RECEPTOR; MONOCLONAL ANTIBODY;

ADULT; AGED; ARTICLE; CANCER GROWTH; CELL DIFFERENTIATION; CONTROLLED STUDY; FEMALE; GASTRECTOMY; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; PRIORITY JOURNAL; STOMACH ADENOCARCINOMA; TUMOR VOLUME;

ADENOCARCINOMA; ADULT; AGED; ANTIBODIES, MONOCLONAL; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTORS, ESTROGEN; STOMACH NEOPLASMS; UP-REGULATION;

EID: 0029811249     PISSN: 00224790     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9098(199611)63:3<166::AID-JSO6>3.0.CO;2-B     Document Type: Article

References (23)

1. Sporn MG, Torado GJ: Autocrine secretion and malignant transformation of cells. N Engl J Med 303:878-880, 1980.
2. Jankowski J, Al-Ravi HJ, Johnston DA, et al.: Growth regulatory peptides in gastric mucosa. Clin Sci 82:581-587, 1992.
3. Kohler M, Bauknecht T, Grimm M, et al.: Epidermal growth factor receptor and transforming growth factor-alpha expression in human ovarian carcinomas. Eur J Cancer 28A: No 8/9, 1432-1437, 1992.
4. Stoscheck CM, King LE Jr.: Role of epidermal growth factor in carcinogenesis. Cancer Res 46:1030-1037, 1986.
5. Ignar-Trowbridge DM, Nelson GK, Bidwell CM, et al.: Coupling of dual signaling pathways: Epidermal growth factor action involves the estrogen receptor. Proc Natl Acad Sci USA 89:4658-4662, 1992.
6. Mukku VR, Stancel GM: Regulation of epidermal growth factor receptor by estrogens. J Biol Chem 260:9820-9824, 1985.
7. Yasui W, Hata J, Yokozaki H, et al.: Interaction between epidermal growth factor and its receptor in progression of human gastric carcinoma. Int J Cancer 41:211-217, 1988.
8. Pfeiffer A, Rothbauer E, Wiebecke B, et al.: Increased epidermal growth factor receptors in gastric carcinomas. Gastroenterology 98:961-967, 1990.
9. Yokozaki H, Takekura N, Takanashi A, et al.: Estrogens receptors in gastric adenocarcinoma: A retrospective immunohistochemical analysis. Virchows Archiv A Pathol Anat 413:297-302, 1988.
10. Koullias G, Lazaris A, Kokkotou E, et al.: Localization of estrogen and progesterone receptors in human gastric cancer. Proc of 1st United European Gastroenterology Week/Athens 1992.
11. Kitaoka H.: Sex hormone dependency and endocrinopathy for patients with diffuse adenocarcinoma of the stomach. Jpn J Cancer Chemother 10:2453-2460, 1983.
12. Yonemura Y, Takamura H, Ninomiya I, et al.: Interrelationship between transforming growth factor-alpha and epidermal growth factor receptor in advanced gastric cancer. Oncology 49:157-161.
13. Sugiyama K, Yonemura Y, Miyazaki I.: Immunohistochemical study of epidermal growth factor and epidermal growth facror receptor in gastric adenocarcinoma. Cancer 63:1557-1561, 1989.
14. Yonemura Y, Sugiyama K, Fujimura T, et al.: Epidermal growth factor receptor and S-phase fractions in gastric carcinoma. Oncology 46:158-161, 1989.
15. Libermann TA, Nusbaum HR, Razon N, et al.: Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumors of glial origin. Nature 313:144-147, 1985.
16. Kojima O, Takahashi T, Kawakami S, et al.: Localization of estrogen receptors in gastric cancer using immunohistochemical staining of monoclonal antibody. Cancer 67:2401-2406, 1991.
17. Matsui M, Kojima O, Uehara Y, Takahashi T.: Characterization of estrogen receptor in human gastric cancer. Cancer 68:305-308, 1991.
18. Perez R, Pascual M, Masias A, Laga A: Epidermal growth factor receptors in human breast cancer. Breast Cancer Res Treat 4:189-193, 1984.
19. Koenders GP, Beex MAVL, Geurts-Moespot A, et al.: Epidermal growth factor receptor-negative tumors are predominantly confined to the subgroup of estradiol receptor-positive human primary breast cancers. Cancer Res 51:4544-4548, 1991.
20. Harrison JD, Watson S, Ellis IO, Morris DL: A study of the effects of estradiol and estramustine on gastriointestinal cell lines. Eur J Surg Oncol 16:116-120, 1990.
21. Kojima O, Takahashi T. Endocrine therapy for scirrhous carcinoma of the stomach. Jpn J Cancer Chemother 13(8):2526-2531, 1986.
22. Harrison JD, Morris DL, Ellis IO, Jones JA, Jackson I. The effect of tamoxifen and estrogen receptor status on survival in gastric carcinoma. Cancer 64:1007-1010, 1989.
23. Lippman M, Bolan G, Huff K.: The effects of estrogens and antiestrogens on hormone-responsive human breast cancer in long term tissue culture. Cancer Res 36:4595-4601, 1976.