메뉴 건너뛰기




Volumn 24, Issue 4 I, 1996, Pages 838-848

Alterations in enzymatic functions in hepatocytes and hepatocellular carcinomas from Ras-transduced livers resemble the effects of insulin

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; DIETHYLNITROSAMINE; INSULIN; PROTEIN P21;

EID: 0029811059     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/jhep.1996.v24.pm0008855186     Document Type: Article
Times cited : (8)

References (85)
  • 2
    • 0027408090 scopus 로고
    • Regulation of gene expression in hepatomas
    • Lea MA. Regulation of gene expression in hepatomas. Int J Biochem 1993; 25:457-469.
    • (1993) Int J Biochem , vol.25 , pp. 457-469
    • Lea, M.A.1
  • 4
    • 0025787250 scopus 로고
    • Primary hepatocellular carcinoma
    • Wands IR, Blum HE. Primary hepatocellular carcinoma. N Engl J Med 1991;325:729-731.
    • (1991) N Engl J Med , vol.325 , pp. 729-731
    • Wands, I.R.1    Blum, H.E.2
  • 5
    • 0025553121 scopus 로고
    • The role of differentiation in the suppression of malignancy
    • Harris H. The role of differentiation in the suppression of malignancy. J Cell Sci 1990;97:5-10.
    • (1990) J Cell Sci , vol.97 , pp. 5-10
    • Harris, H.1
  • 6
    • 0026043269 scopus 로고
    • Retroviral oncogenes: Interrelationships between neoplastic transformation and cell differentiation
    • Auersperg N, Roskelley C. Retroviral oncogenes: interrelationships between neoplastic transformation and cell differentiation. Crit Rev Oncog 1991;2:125-136.
    • (1991) Crit Rev Oncog , vol.2 , pp. 125-136
    • Auersperg, N.1    Roskelley, C.2
  • 7
    • 0017110066 scopus 로고
    • Cancer, retrodifferentiation, and the myth of Faust
    • Uriel J. Cancer, retrodifferentiation, and the myth of Faust. Cancer Res 1976;36:4269-4275.
    • (1976) Cancer Res , vol.36 , pp. 4269-4275
    • Uriel, J.1
  • 8
    • 0026031601 scopus 로고
    • CCAAT/enhancer binding protein: A component of a differentiation switch
    • Umek RM, Friedman AD, McKnight SL. CCAAT/enhancer binding protein: a component of a differentiation switch. Science 1991;251:288-292.
    • (1991) Science , vol.251 , pp. 288-292
    • Umek, R.M.1    Friedman, A.D.2    McKnight, S.L.3
  • 9
    • 0028079763 scopus 로고
    • Vitamin A, differentiation and cancer
    • Love JM, Gudas LJ. Vitamin A, differentiation and cancer. Curr Opin Cell Biol 1994;6:825-831.
    • (1994) Curr Opin Cell Biol , vol.6 , pp. 825-831
    • Love, J.M.1    Gudas, L.J.2
  • 10
    • 0027746111 scopus 로고
    • Regulation of the differentiation of diploid and some aneuploid rat liver epithelial (stemlike) cells by the hepatic microenvironment
    • Coleman WB, Wennerberg AE, Smith GJ, Grisham JW. Regulation of the differentiation of diploid and some aneuploid rat liver epithelial (stemlike) cells by the hepatic microenvironment. Am J Pathol 1993;142:1373-1382.
    • (1993) Am J Pathol , vol.142 , pp. 1373-1382
    • Coleman, W.B.1    Wennerberg, A.E.2    Smith, G.J.3    Grisham, J.W.4
  • 11
    • 0028978268 scopus 로고
    • High Km glucose-phosphorylating activities in a range of tumor cell lines and inhibition of rates of tumor growth by the specific enzyme inhibitor mannoheptulose
    • Board M, Colquhoun A, Newsholme EA. High Km glucose-phosphorylating activities in a range of tumor cell lines and inhibition of rates of tumor growth by the specific enzyme inhibitor mannoheptulose. Cancer Res 1995; 55:3278-3285.
    • (1995) Cancer Res , vol.55 , pp. 3278-3285
    • Board, M.1    Colquhoun, A.2    Newsholme, E.A.3
  • 12
    • 0028897113 scopus 로고
    • Transcriptional regulation by extracellular signals: Mechanisms and specificity
    • Hill CS, Treisman R. Transcriptional regulation by extracellular signals: mechanisms and specificity. Cell 1995;80:199-211.
    • (1995) Cell , vol.80 , pp. 199-211
    • Hill, C.S.1    Treisman, R.2
  • 13
    • 0027138356 scopus 로고
    • The role of p21-ras in receptor tyrosine kinase signaling
    • Medema RH, Bos JL. The role of p21-ras in receptor tyrosine kinase signaling. Crit Rev Oncog 1993;4:615-661.
    • (1993) Crit Rev Oncog , vol.4 , pp. 615-661
    • Medema, R.H.1    Bos, J.L.2
  • 14
    • 0025323757 scopus 로고
    • Detection of activated c-H-ras oncogene in hepatocellular carcinomas developing in transgenic mice harboring albumin promoter-regulated SV40 gene
    • Lee G-H, Li H, Ohtake K, Nomura K, Hino O, Furata Y, Aizawa S, et al. Detection of activated c-H-ras oncogene in hepatocellular carcinomas developing in transgenic mice harboring albumin promoter-regulated SV40 gene. Carcinogenesis 1990;11:1145-1148.
    • (1990) Carcinogenesis , vol.11 , pp. 1145-1148
    • Lee, G.-H.1    Li, H.2    Ohtake, K.3    Nomura, K.4    Hino, O.5    Furata, Y.6    Aizawa, S.7
  • 15
    • 0022588196 scopus 로고
    • Expression of H-ras and c-myc proto-oncogenes in isolated GGT-positive rat hepatocytes and in hepatocellular carcinomas induced by DEN
    • Beer D, Schwarz M, Sawada N, Pitot HC. Expression of H-ras and c-myc proto-oncogenes in isolated GGT-positive rat hepatocytes and in hepatocellular carcinomas induced by DEN. Cancer Res 1986;46:2435-2441.
    • (1986) Cancer Res , vol.46 , pp. 2435-2441
    • Beer, D.1    Schwarz, M.2    Sawada, N.3    Pitot, H.C.4
  • 16
    • 0026092941 scopus 로고
    • Mutational activation of the c-Ha-ras gene in liver tumors of differents rodent strains: Correlation with susceptibility to hepatocarcinogenesis
    • Buchmann A, Bauer-Hoffman R, Mahr J, Drinkwater NR, Luz A, Schwartz M. Mutational activation of the c-Ha-ras gene in liver tumors of differents rodent strains: correlation with susceptibility to hepatocarcinogenesis. Proc Natl Acad Sci U S A 1991;88:911-915.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 911-915
    • Buchmann, A.1    Bauer-Hoffman, R.2    Mahr, J.3    Drinkwater, N.R.4    Luz, A.5    Schwartz, M.6
  • 17
    • 0023473198 scopus 로고
    • Analysis of ras genes and linked viral sequences in rat hepatocarcinogenesis
    • Chandar N, Lombardi B, Schulz W, Locker J. Analysis of ras genes and linked viral sequences in rat hepatocarcinogenesis. Am J Pathol 1987;129: 232-241.
    • (1987) Am J Pathol , vol.129 , pp. 232-241
    • Chandar, N.1    Lombardi, B.2    Schulz, W.3    Locker, J.4
  • 18
    • 0028287495 scopus 로고
    • Absence of p53 mutations and various frequencies of Ki-ras exon 1 mutations in rat hepatic tumors induced by different carcinogens
    • Tokusashi Y, Fukada I, Ogawa K. Absence of p53 mutations and various frequencies of Ki-ras exon 1 mutations in rat hepatic tumors induced by different carcinogens. Mol Carcinog 1994;10:45-51.
    • (1994) Mol Carcinog , vol.10 , pp. 45-51
    • Tokusashi, Y.1    Fukada, I.2    Ogawa, K.3
  • 19
    • 0021912710 scopus 로고
    • Expression of c-Ki-ras, c-Ha-ras, and c-myc in specific cell types during hepatocarcinogenesis
    • Yaswen P, Goyette M, Shank PR, Fausto N. Expression of c-Ki-ras, c-Ha-ras, and c-myc in specific cell types during hepatocarcinogenesis. Mol Cell Biol 1985;5:780-786.
    • (1985) Mol Cell Biol , vol.5 , pp. 780-786
    • Yaswen, P.1    Goyette, M.2    Shank, P.R.3    Fausto, N.4
  • 20
    • 0027292743 scopus 로고
    • Dose-dependent ras mutation spectra in N-nitrosodiethylamine induced mouse liver tumors and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induced mouse lung tumors
    • Chen B, Liu L, Castonguay A, Maronpot RR, Anderson MW, You M. Dose-dependent ras mutation spectra in N-nitrosodiethylamine induced mouse liver tumors and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induced mouse lung tumors. Carcinogenesis 1993;14:1603-1608.
    • (1993) Carcinogenesis , vol.14 , pp. 1603-1608
    • Chen, B.1    Liu, L.2    Castonguay, A.3    Maronpot, R.R.4    Anderson, M.W.5    You, M.6
  • 21
    • 0025169651 scopus 로고
    • Analysis of ras gene mutations in human hepatic malignant tumors by polymerase chain reaction and direct sequencing
    • Tada M, Omata M, Ohto M. Analysis of ras gene mutations in human hepatic malignant tumors by polymerase chain reaction and direct sequencing. Cancer Res 1990;50:1121-1124.
    • (1990) Cancer Res , vol.50 , pp. 1121-1124
    • Tada, M.1    Omata, M.2    Ohto, M.3
  • 22
    • 0024801490 scopus 로고
    • Low incidence of point mutations of c-Ki-ras and N-ras oncogenes in human hepatocellular carcinoma
    • Tsuda H, Hirohashi S, Shimosato Y, Ino Y, Yoshida T, Terasa M. Low incidence of point mutations of c-Ki-ras and N-ras oncogenes in human hepatocellular carcinoma. Jpn J Cancer Res 1989;80:196-199.
    • (1989) Jpn J Cancer Res , vol.80 , pp. 196-199
    • Tsuda, H.1    Hirohashi, S.2    Shimosato, Y.3    Ino, Y.4    Yoshida, T.5    Terasa, M.6
  • 23
    • 0026080914 scopus 로고
    • Point mutation, allelic loss and increased methylation of c-Ha-ras gene in human hepatocellular carcinoma
    • Ogato N, Kamimura T, Asakura H. Point mutation, allelic loss and increased methylation of c-Ha-ras gene in human hepatocellular carcinoma. HEPATOLOGY 1991;13:31-37.
    • (1991) Hepatology , vol.13 , pp. 31-37
    • Ogato, N.1    Kamimura, T.2    Asakura, H.3
  • 25
    • 0025318985 scopus 로고
    • Characterization of a transforming N-ras gene in the human hepatoma cell line Hep G2: Additional evidence for the importance of c-myc and ras cooperation in hepatocarcinogenesis
    • Richards CA, Short SA, Thorgeirrson SS, Huber BE. Characterization of a transforming N-ras gene in the human hepatoma cell line Hep G2: additional evidence for the importance of c-myc and ras cooperation in hepatocarcinogenesis. Cancer 1990;50:1521-1527.
    • (1990) Cancer , vol.50 , pp. 1521-1527
    • Richards, C.A.1    Short, S.A.2    Thorgeirrson, S.S.3    Huber, B.E.4
  • 26
  • 27
    • 0028158811 scopus 로고
    • Liver-directed gene therapy: Quantitative evaluation of promoter elements using in vivo retroviral transduction
    • Rettinger S, Kennedy S, Wu X, Flye MW, Ponder KP. Liver-directed gene therapy: quantitative evaluation of promoter elements using in vivo retroviral transduction. Proc Natl Acad Sci U S A. 1994;91:1460-1464.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 1460-1464
    • Rettinger, S.1    Kennedy, S.2    Wu, X.3    Flye, M.W.4    Ponder, K.P.5
  • 28
    • 0025997947 scopus 로고
    • The encephalomyocarditis virus internal ribosome entry site allows efficient co-expression of two genes from a recombinant provirus in cultured cells and in embryos
    • Ghattas IR, Sanes JR, Majors JE. The encephalomyocarditis virus internal ribosome entry site allows efficient co-expression of two genes from a recombinant provirus in cultured cells and in embryos. Mol Cell Biol 1991; 11:5848-5857.
    • (1991) Mol Cell Biol , vol.11 , pp. 5848-5857
    • Ghattas, I.R.1    Sanes, J.R.2    Majors, J.E.3
  • 29
    • 0025008962 scopus 로고
    • Positive and negative elements control the limited hepatocyte and choroid plexus expression of transthyretin in transgenic mice
    • Yan C, Costa R, Darnell J, Chen J, Van Dyke T. Positive and negative elements control the limited hepatocyte and choroid plexus expression of transthyretin in transgenic mice. EMBO J 1990;9:869-878.
    • (1990) EMBO J , vol.9 , pp. 869-878
    • Yan, C.1    Costa, R.2    Darnell, J.3    Chen, J.4    Van Dyke, T.5
  • 30
    • 0021710675 scopus 로고
    • Human colon carcinoma Ki-ras-2 oncogene and its corresponding proto-oncogene
    • McCoy MS, Bargmann CI, Weinberg RA. Human colon carcinoma Ki-ras-2 oncogene and its corresponding proto-oncogene. Mol Cell Biol 1984;4: 1577-1582.
    • (1984) Mol Cell Biol , vol.4 , pp. 1577-1582
    • McCoy, M.S.1    Bargmann, C.I.2    Weinberg, R.A.3
  • 31
    • 0026023289 scopus 로고
    • Targeted disruption of the c-src protooncogene leads to osteopetrosis in mice
    • Soriano P, Montgomery C, Geske R, Bradley A. Targeted disruption of the c-src protooncogene leads to osteopetrosis in mice. Cell 1991;64:693-702.
    • (1991) Cell , vol.64 , pp. 693-702
    • Soriano, P.1    Montgomery, C.2    Geske, R.3    Bradley, A.4
  • 32
    • 0024239024 scopus 로고
    • Construction and use of a safe and efficient amphotropic packaging cell line
    • Markowitz D, Goff S, Bank A. Construction and use of a safe and efficient amphotropic packaging cell line. Virology 1988;167:400-406.
    • (1988) Virology , vol.167 , pp. 400-406
    • Markowitz, D.1    Goff, S.2    Bank, A.3
  • 33
    • 0014604721 scopus 로고
    • Murine sarcoma and leukemia viruses: Assay using clonal lines of contact inhibited mouse cells
    • Jainchill JL, Aaronson SA, Todaro GJ. Murine sarcoma and leukemia viruses: assay using clonal lines of contact inhibited mouse cells. J Virol 1969;4:549-553.
    • (1969) J Virol , vol.4 , pp. 549-553
    • Jainchill, J.L.1    Aaronson, S.A.2    Todaro, G.J.3
  • 36
    • 16044362713 scopus 로고
    • Histology and histochemistry
    • Thurman RG, Kauffman FC, Jungermann K, eds. New York: Plenum
    • Sasse D. Histology and histochemistry. In: Thurman RG, Kauffman FC, Jungermann K, eds. Regulation of hepatic metabolism. New York: Plenum, 1986:78-83.
    • (1986) Regulation of Hepatic Metabolism , pp. 78-83
    • Sasse, D.1
  • 37
    • 0344517896 scopus 로고
    • The fine localization of dehydrogenases in the nervous system
    • Thomas E, Pearse AGE. The fine localization of dehydrogenases in the nervous system. Histochemie 1961;2:266-282.
    • (1961) Histochemie , vol.2 , pp. 266-282
    • Thomas, E.1    Pearse, A.G.E.2
  • 38
    • 0015545496 scopus 로고
    • Further enzyme histochemical observations on the segmentation of the proximal tubules in the kidney of the male rat
    • Jacobsen NO, Jørgensen F. Further enzyme histochemical observations on the segmentation of the proximal tubules in the kidney of the male rat. Histochemie 1973;34:11-32.
    • (1973) Histochemie , vol.34 , pp. 11-32
    • Jacobsen, N.O.1    Jørgensen, F.2
  • 41
    • 0018151116 scopus 로고
    • NADP-dependent dehydrogenases in rat liver parenchyma
    • Rieder H, Teutsch HF, Sasse D. NADP-dependent dehydrogenases in rat liver parenchyma. Histochem Cell Biol 1978;56:283-298.
    • (1978) Histochem Cell Biol , vol.56 , pp. 283-298
    • Rieder, H.1    Teutsch, H.F.2    Sasse, D.3
  • 42
    • 0342738866 scopus 로고
    • Enzyme histochemistry: Diagnostic applications
    • Bancroft JD, Stevens A, eds. Edinburgh: Churchill Livingstone
    • Stevens A. Enzyme histochemistry: diagnostic applications. In: Bancroft JD, Stevens A, eds. Theory and practice of histological techniques. Edinburgh: Churchill Livingstone, 1990:1:401-411.
    • (1990) Theory and Practice of Histological Techniques , vol.1 , pp. 401-411
    • Stevens, A.1
  • 44
    • 0345260946 scopus 로고
    • Distribution of G6Pase in the liver of the mouse
    • Chiquoine AD. Distribution of G6Pase in the liver of the mouse. J Histochem Cytochem 1953;1:429-435.
    • (1953) J Histochem Cytochem , vol.1 , pp. 429-435
    • Chiquoine, A.D.1
  • 45
    • 70449159416 scopus 로고
    • Histochemistry of hepatic phosphatases at a physiologic pH
    • Wachstein M, Meisel E. Histochemistry of hepatic phosphatases at a physiologic pH. Am J Clin Pathol 1957;13-23.
    • (1957) Am J Clin Pathol , pp. 13-23
    • Wachstein, M.1    Meisel, E.2
  • 46
    • 0014266510 scopus 로고
    • Cytochemical demonstration of ornithine carbamoyltransferase activity in liver mitochondria of rat and mouse
    • Mizutani A. Cytochemical demonstration of ornithine carbamoyltransferase activity in liver mitochondria of rat and mouse. J Histochem Cytochem 1968;16:172-180.
    • (1968) J Histochem Cytochem , vol.16 , pp. 172-180
    • Mizutani, A.1
  • 47
    • 0026034388 scopus 로고
    • Re-evaluation of the specificity of adenylyl (β,γ-methylene)diphosphonate as a substrate for adenylate cyclase
    • Mayer D, Hacker HJ, Bannasch P. Re-evaluation of the specificity of adenylyl (β,γ-methylene)diphosphonate as a substrate for adenylate cyclase. Histochem J 1991;23:100-106.
    • (1991) Histochem J , vol.23 , pp. 100-106
    • Mayer, D.1    Hacker, H.J.2    Bannasch, P.3
  • 49
    • 0021185745 scopus 로고
    • Histochemical and immunohistochemical localization of hexokinase isoenzymes in normal rat liver
    • Lawrence GM, Trayer IP, Walker DG. Histochemical and immunohistochemical localization of hexokinase isoenzymes in normal rat liver. Histochem J 1984;16:1099-1111.
    • (1984) Histochem J , vol.16 , pp. 1099-1111
    • Lawrence, G.M.1    Trayer, I.P.2    Walker, D.G.3
  • 50
    • 0017080954 scopus 로고
    • Quantitative cytochemical measurement of glyceraldehyde 3-phosphate dehydrogenase activity
    • Henderson B. Quantitative cytochemical measurement of glyceraldehyde 3-phosphate dehydrogenase activity. Histochem Cell Biol 1976;48:191-204.
    • (1976) Histochem Cell Biol , vol.48 , pp. 191-204
    • Henderson, B.1
  • 51
    • 0023791896 scopus 로고
    • Histochemical and microbiochemical demonstration of reduced pyruvate kinase activity in thioacetamide-induced neoplastic nodules of rat liver
    • Klimek F, Moore MA, Schneider E, Bannasch P. Histochemical and microbiochemical demonstration of reduced pyruvate kinase activity in thioacetamide-induced neoplastic nodules of rat liver. Histochem Cell Biol 1988;90:37-42.
    • (1988) Histochem Cell Biol , vol.90 , pp. 37-42
    • Klimek, F.1    Moore, M.A.2    Schneider, E.3    Bannasch, P.4
  • 52
    • 0024460181 scopus 로고
    • Improved retroviral vectors for gene transfer and expression
    • Miller AD, Rosman GJ. Improved retroviral vectors for gene transfer and expression. Biotechniques 1989;7:980-987.
    • (1989) Biotechniques , vol.7 , pp. 980-987
    • Miller, A.D.1    Rosman, G.J.2
  • 53
    • 0001756836 scopus 로고
    • Use of E. coli lac Z (β-galactosidase) as a reporter gene
    • Murray EJ, Walker JM, eds. Totowa: Humana Press Inc
    • MacGregor GR, Nolan GP, Fiering S, Roederer M, Herzenberg LA. Use of E. coli lac Z (β-galactosidase) as a reporter gene. In: Murray EJ, Walker JM, eds. Methods in molecular biology. Vol 7. Totowa: Humana Press Inc, 1993:317-327.
    • (1993) Methods in Molecular Biology , vol.7 , pp. 317-327
    • MacGregor, G.R.1    Nolan, G.P.2    Fiering, S.3    Roederer, M.4    Herzenberg, L.A.5
  • 55
    • 0014117238 scopus 로고
    • β-Hydroxybutyrate dehydrogenase activity in liver and liver tumors
    • Ohe K, Morris HP, Weinhouse S. β-Hydroxybutyrate dehydrogenase activity in liver and liver tumors. Cancer Res 1967;27:1360-1371.
    • (1967) Cancer Res , vol.27 , pp. 1360-1371
    • Ohe, K.1    Morris, H.P.2    Weinhouse, S.3
  • 56
    • 0026673779 scopus 로고
    • Development of liver tumors in transforming growth factor α transgenic mice
    • Lee G-H, Merlino G, Fausto N. Development of liver tumors in transforming growth factor α transgenic mice. Cancer Res 1992;52:5162-5170.
    • (1992) Cancer Res , vol.52 , pp. 5162-5170
    • Lee, G.-H.1    Merlino, G.2    Fausto, N.3
  • 58
    • 0001459219 scopus 로고
    • Neoplasms of the liver
    • Schiff L, Schiff ER, eds. Philadelphia: Lippincott
    • Okuda K, Kojiro M, Okuda H. Neoplasms of the liver. In: Schiff L, Schiff ER, eds. Diseases of the liver. 7th ed. Philadelphia: Lippincott, 1993:1236-1265.
    • (1993) Diseases of the Liver. 7th Ed. , pp. 1236-1265
    • Okuda, K.1    Kojiro, M.2    Okuda, H.3
  • 59
    • 0027399622 scopus 로고
    • Reversal of ras-induced inhibition of gap-junctional intercellular communication, transformation, and tumorigeneses by lovastatin
    • Ruch RJ, Madhukar BV, Trosko JE, Klaunig JE. Reversal of ras-induced inhibition of gap-junctional intercellular communication, transformation, and tumorigeneses by lovastatin. Mol Carcinog 1993;7:50-59.
    • (1993) Mol Carcinog , vol.7 , pp. 50-59
    • Ruch, R.J.1    Madhukar, B.V.2    Trosko, J.E.3    Klaunig, J.E.4
  • 61
    • 0027213688 scopus 로고
    • Inhibitors of Ras farnesyltransferases
    • Tamanoi F. Inhibitors of Ras farnesyltransferases. Trends Biochem Sci 1993;18:349-353.
    • (1993) Trends Biochem Sci , vol.18 , pp. 349-353
    • Tamanoi, F.1
  • 62
    • 0000893548 scopus 로고
    • Fatty liver: Biochemical and clinical aspects
    • Schiff L, Schiff ER, eds. Philadelphia: Lippincott
    • Alpers DH, Sabesin SM, White HM. Fatty liver: biochemical and clinical aspects. In: Schiff L, Schiff ER, eds. Diseases of the liver. 7th ed. Philadelphia: Lippincott, 1993;2:825-855.
    • (1993) Diseases of the Liver. 7th Ed. , vol.2 , pp. 825-855
    • Alpers, D.H.1    Sabesin, S.M.2    White, H.M.3
  • 63
    • 0028278931 scopus 로고
    • The insulin receptor; structure, function, and signaling
    • Lee J, Pilch PF. The insulin receptor; structure, function, and signaling. Am J Physiol 1994;266:C319-C334.
    • (1994) Am J Physiol , vol.266
    • Lee, J.1    Pilch, P.F.2
  • 64
    • 0028158283 scopus 로고
    • Transcriptional control of metabolic regulation genes by carbohydrates
    • Vaulont S, Kahn A. Transcriptional control of metabolic regulation genes by carbohydrates. FASEB J 1994;8:28-35.
    • (1994) FASEB J , vol.8 , pp. 28-35
    • Vaulont, S.1    Kahn, A.2
  • 65
    • 0027935491 scopus 로고
    • Activation of ribosomal protein S6 kinase does not increase glycogen synthetase or glucose transport in rat adipocytes
    • Lin TA, Lawrence JC. Activation of ribosomal protein S6 kinase does not increase glycogen synthetase or glucose transport in rat adipocytes. J Biol Chem 1994;269:21255-21261.
    • (1994) J Biol Chem , vol.269 , pp. 21255-21261
    • Lin, T.A.1    Lawrence, J.C.2
  • 66
    • 0029009331 scopus 로고
    • Ras-in dependent and wortmannin sensitive activation of glycogen synthetase by insulin in Chinese hamster ovary cells
    • Sakaue H, Hara K, Noguchi T, Matozaki T, Kotani K, Ogawa W, Yonezawa K, et al. Ras-in dependent and wortmannin sensitive activation of glycogen synthetase by insulin in Chinese hamster ovary cells. J Biol Chem 1995; 270:11304-11309.
    • (1995) J Biol Chem , vol.270 , pp. 11304-11309
    • Sakaue, H.1    Hara, K.2    Noguchi, T.3    Matozaki, T.4    Kotani, K.5    Ogawa, W.6    Yonezawa, K.7
  • 67
    • 0025069255 scopus 로고
    • Altered hepatic foci: Their role in murine hepatocarcinogenesis
    • Pitot HC. Altered hepatic foci: their role in murine hepatocarcinogenesis. Annu Rev Toxicol 1990;30:465-500.
    • (1990) Annu Rev Toxicol , vol.30 , pp. 465-500
    • Pitot, H.C.1
  • 68
    • 0018967816 scopus 로고
    • Hepatocellular glycogenesis and hepatocarcinogenesis
    • Bannasch P, Mayer D, Hacker H-J. Hepatocellular glycogenesis and hepatocarcinogenesis. Biochem Biophys Acta 1980;605:217-245.
    • (1980) Biochem Biophys Acta , vol.605 , pp. 217-245
    • Bannasch, P.1    Mayer, D.2    Hacker, H.-J.3
  • 69
    • 0018955647 scopus 로고
    • The pathogenesis of rat liver cancer caused by chemical carcinogens
    • Williams GM. The pathogenesis of rat liver cancer caused by chemical carcinogens. Biochem Biophys Acta 1980;605:167-189.
    • (1980) Biochem Biophys Acta , vol.605 , pp. 167-189
    • Williams, G.M.1
  • 70
    • 0021957703 scopus 로고
    • Regulation and expression of four cytochrome P-450 isoenzymes, NADPH-cytochrome P-450 reductase, the glutathione transferases B and C and microsomal epoxide hydrolase in preneoplastic and neoplastic lesions in rat liver
    • Buchmann A, Kuhlmann W, Schwartz M, Kunz W, Wolf CR, Moll E, Friedberg T, et al. Regulation and expression of four cytochrome P-450 isoenzymes, NADPH-cytochrome P-450 reductase, the glutathione transferases B and C and microsomal epoxide hydrolase in preneoplastic and neoplastic lesions in rat liver. Carcinogenesis 1985;6:513-521.
    • (1985) Carcinogenesis , vol.6 , pp. 513-521
    • Buchmann, A.1    Kuhlmann, W.2    Schwartz, M.3    Kunz, W.4    Wolf, C.R.5    Moll, E.6    Friedberg, T.7
  • 71
    • 0028197253 scopus 로고
    • Suppression of albumin enhancer activity by H-ras and AP1 in hepatocyte cell lines
    • Hu J, Isom HC. Suppression of albumin enhancer activity by H-ras and AP1 in hepatocyte cell lines. Mol Cell Biol 1994;14:1531-1543.
    • (1994) Mol Cell Biol , vol.14 , pp. 1531-1543
    • Hu, J.1    Isom, H.C.2
  • 72
    • 0025343853 scopus 로고
    • Isolation, culture, and transplantation of intrahepatic biliary epithelial cells and oval cells
    • Sirica AE, Mathis GA, Sano N, Elmore LW. Isolation, culture, and transplantation of intrahepatic biliary epithelial cells and oval cells. Pathobiology 1990;58:44-64.
    • (1990) Pathobiology , vol.58 , pp. 44-64
    • Sirica, A.E.1    Mathis, G.A.2    Sano, N.3    Elmore, L.W.4
  • 73
    • 0002867561 scopus 로고
    • Energy metabolism
    • Arias IM, Boyer JL, Fausto N, Jakoby WB, Schachter D, Shafritz DA, eds. New York: Raven
    • Seifter S, Englard S. Energy metabolism. In: Arias IM, Boyer JL, Fausto N, Jakoby WB, Schachter D, Shafritz DA, eds. The liver: biology and pathobiology. New York: Raven, 1994;323-364.
    • (1994) The Liver: Biology and Pathobiology , pp. 323-364
    • Seifter, S.1    Englard, S.2
  • 74
    • 14444285248 scopus 로고
    • Mechanisms whereby insulin may regulate intracellular events
    • Ashcroft FM, Ashcroft SJH, eds. New York: IRL Press
    • Denton RM, Tavare JM. Mechanisms whereby insulin may regulate intracellular events. In: Ashcroft FM, Ashcroft SJH, eds. Insulin: molecular biology to pathology. New York: IRL Press, 1992:235-256.
    • (1992) Insulin: Molecular Biology to Pathology , pp. 235-256
    • Denton, R.M.1    Tavare, J.M.2
  • 75
    • 0025069255 scopus 로고
    • Altered hepatic foci: Their role in murine hepatocarcinogenesis
    • Pitot HC. Altered hepatic foci: their role in murine hepatocarcinogenesis. Annu Rev Pharmacol Toxicol 1990;30:465-500.
    • (1990) Annu Rev Pharmacol Toxicol , vol.30 , pp. 465-500
    • Pitot, H.C.1
  • 76
    • 16044374438 scopus 로고
    • Carbohydrate metabolism in hepatic pre-neoplasia
    • Bannasch P, Keppler D, Weber G, eds. Boston: Kluwer Academic Publishers
    • Mayer D, Klimek F, Hacker HJ, Bannasch P. Carbohydrate metabolism in hepatic pre-neoplasia. In: Bannasch P, Keppler D, Weber G, eds. Liver cell carcinoma. Boston: Kluwer Academic Publishers, 1988:329-346.
    • (1988) Liver Cell Carcinoma , pp. 329-346
    • Mayer, D.1    Klimek, F.2    Hacker, H.J.3    Bannasch, P.4
  • 77
    • 0027939369 scopus 로고
    • Hepatic preneoplasia in hepatitis B virus transgenic mice
    • Toshkov I, Chisari FV, Bannasch P. Hepatic preneoplasia in hepatitis B virus transgenic mice. HEPATOLOGY 1994;20:1162-1172.
    • (1994) Hepatology , vol.20 , pp. 1162-1172
    • Toshkov, I.1    Chisari, F.V.2    Bannasch, P.3
  • 78
    • 0017580461 scopus 로고
    • Enzymology of cancer cells
    • Weber G. Enzymology of cancer cells. N Engl J Med 1977;296:541-551.
    • (1977) N Engl J Med , vol.296 , pp. 541-551
    • Weber, G.1
  • 79
    • 0025826137 scopus 로고
    • Regulation of gene expression by insulin
    • O'Brian RM, Granner DK. Regulation of gene expression by insulin. Biochem J 1991;278:609-619.
    • (1991) Biochem J , vol.278 , pp. 609-619
    • O'Brian, R.M.1    Granner, D.K.2
  • 80
    • 0027373851 scopus 로고
    • Isoenzyme shift from glucokinase to hexokinase is not an early but a late event in hepatocarcinogenesis
    • Klimek F, Bannasch P. Isoenzyme shift from glucokinase to hexokinase is not an early but a late event in hepatocarcinogenesis. Carcinogenesis 1993;14:1857-1861.
    • (1993) Carcinogenesis , vol.14 , pp. 1857-1861
    • Klimek, F.1    Bannasch, P.2
  • 81
    • 0019782204 scopus 로고
    • NADP-dependent dehydrogenases in rat liver parenchyma
    • Rieder H. NADP-dependent dehydrogenases in rat liver parenchyma. Histochem Cell Biol 1981;72:579-615.
    • (1981) Histochem Cell Biol , vol.72 , pp. 579-615
    • Rieder, H.1
  • 83
    • 0015079872 scopus 로고
    • Histochemical analysis of hyperplastic lesions and hepatomas of the liver of rats red 2-fluorenylacetamide
    • Kitagawa T. Histochemical analysis of hyperplastic lesions and hepatomas of the liver of rats red 2-fluorenylacetamide. Jpn J Cancer Res 1971;62: 207-216.
    • (1971) Jpn J Cancer Res , vol.62 , pp. 207-216
    • Kitagawa, T.1
  • 84
    • 16044372790 scopus 로고
    • Biochemical strategy of hepatocellular carcinoma
    • Bannasch P, Keppler D, Weber G, eds. Boston: Kluwer Academic Publishers
    • Weber G. Biochemical strategy of hepatocellular carcinoma. In: Bannasch P, Keppler D, Weber G, eds. Liver cell carcinoma. Boston: Kluwer Academic Publishers, 1988:361-374.
    • (1988) Liver Cell Carcinoma , pp. 361-374
    • Weber, G.1
  • 85
    • 0015913762 scopus 로고
    • Apparent unbalance between the activities of 6-phosphogluconate and glucose-6-phosphate dehydrogenases in rat liver
    • Sapag-Hagar M, Lagunas R, Sols A. Apparent unbalance between the activities of 6-phosphogluconate and glucose-6-phosphate dehydrogenases in rat liver. Biochem Biophys Res Commun 1973;50:179-185.
    • (1973) Biochem Biophys Res Commun , vol.50 , pp. 179-185
    • Sapag-Hagar, M.1    Lagunas, R.2    Sols, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.