Protein Expression During Murine Thymus Differentiation

Developmental Immunology

Volumn 5, Issue 1, 1996, Pages 53-66

  Rudolffrey, Johann ^a   Hartmann, Klaus Ulrich ^b   Lefkovits, Ivan ^a  

^a BASEL INSTITUTE FOR IMMUNOLOGY   (Switzerland)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

Database; image analysis; protein expression; thymus development; two dimensional gel electrophoresis

Indexed keywords

COMPLEMENTARY DNA; POLYPEPTIDE; PROTEIN; REGULATOR PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; CELL DIFFERENTIATION; CONTROLLED STUDY; DENSITOMETRY; DNA LIBRARY; DNA SEQUENCE; EMBRYO; EMBRYO DEVELOPMENT; GEL ELECTROPHORESIS; IMAGE ANALYSIS; IMMUNE SYSTEM; LYMPHOCYTE DIFFERENTIATION; MOLECULAR WEIGHT; MOUSE; NEWBORN; NONHUMAN; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; THYMUS;

ANIMALS; AUTORADIOGRAPHY; CELL DIFFERENTIATION; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; MICE; MICE, INBRED C57BL; PROTEIN BIOSYNTHESIS; THYMUS GLAND;

EID: 0029810505     PISSN: 10446672     EISSN: None     Source Type: Journal    
DOI: 10.1155/1996/64697     Document Type: Article

References (25)

1. Anderson N.G., and Anderson N.L. (1978). Analytical techniques for cell fractions. XXI. Two-dimensional analysis of serum and tissue proteins. Multiple isoelectric focusing. Anal. Biochem. 85: 331–340.
2. Ardavin C., Wu L., Li C.L., and Shortman K. (1993). Thymic dendritic cells and T cells develop simultaneously in the thymus from a common precursor population. Nature 362: 761–763.
3. Béhar G., Coleclough C., Auffray C., and Lefkovits I. (1995). Analysis of individual clones from an ordered cDNA library. Appl. Theor. Electrophor.: In press.
4. Boyd R.L., and Hugo P. (1991). Towards an integrated view of thymopoiesis. Immunol. Today 12: 71–79.
5. Hartmann K.-U., von Eckardstein S., and Darwin E. (1989). Differentiation of epithelial stroma during ontogenesis of the thymus in mice: A speculation on the origin of the thymus as a sensory organ. Thymus 13: 195–200.
6. Imhof B.A., Ruiz P., Hesse B., Palacios R., and Dunon D. [1991]. EA-1, a novel adhesion molecule involved in the homing of progenitor T lymphocytes to the thymus. J. Cell. Biol. 114: 1069–1078.
7. Ivanov V., Merkenschlager M., and Ceredig R. (1993). Antioxidant treatment of thymic organ cultures decreases NF-kB and TCF1 (alpha) transcription factor activities and inhibits αβ T cell development. J. Immunol. 151: 4694–4704.
8. Jotereau E, Heuze F., Salomon V.; and Gascan H. (1987). Cell kinetics in the fetal mouse thymus: precursor cell input, proliferation, and emigration. J. Immunol. 138: 1026–1030.
9. Kettman J., Coleclough C., and Lefkovits I. (1994). Lymphocyte proteinpaedia stage two: T-cell polypeptides from a partitioned cDNA library revealed by the dual decay method. Int. Arch. Allergy Immunol. 103: 131–142.
10. Kisielow P., and von Boehmer H. (1995). Development and selection of T cells: facts and puzzles. Adv. Immunol. 58: 87–209.
11. Lefkovits I., Frey J.R., and Coleclough C. (1995b). Human lymphocyte cDNA ordered library analyzed by 2D gel electrophoresis 2. Frequency distribution of mRNA populations. Appl. Theor. Electrophor.: 5: 43–47.
12. Lefkovits I., Frey J.R., Kuhn L., Kettman J.R., Béhar G., Auffray C., Hoffmann J.-P., and Coleclough C. (1995). Human lymphocyte cDNA ordered library analyzed by 2D gel electrophoresis 1. Pooling strategy and matching of gel patterns. Appl. Theor. Electrophor.: 5: 35–42.
13. Lefkovits I., Kettman J.R., and Coleclough C. (1990). A strategy for founding a global lymphocyte proteinpaedia and gene catalogue. Immunol. Today 11: 157–162.
14. Lefkovits I., Kuhn L., Valiron O., Merle A., and Kettman J. (1988). Toward an objective classification of cells in the immune system. Proc. Natl Acad. Sci. USA 85: 3565–3369.
15. Lefkovits I., Young P., Kuhn L., Kettman J., Gemmell A., Tollaksen S., Anderson L., and Anderson N. (1985). Use of large-scale two-dimensional ISODALT gel electrophoresis system in immunology. In: Immunological Methods, vol. 3, Lefkovits I, and Pernis B., Eds. (Orlando, FL: Academic Press), pp. 163–185.
16. O’Farrell P.H. (1975). High resolution two-dimensional electrophoresis of proteins. J. Biol. Chem. 250: 4007–4021.
17. Palacios R., and Samaridis J. (1991). Thymus colonization in the developing mouse embryo. Eur. J. Immunol. 21: 109–113.
18. Pluschke G., and Lefkovits I. (1990). Analysis of two-dimensional gel electrophoretic protein patterns upon in vivo labeling of mice. In: Immunological Methods, vol. 4, Lefkovits I, and Pernis B., Eds. (Orlando, FL: Academic Press), pp. 153–164.
19. Righetti P.G., Chiari M., and Gelfi C. (1988). Immobilized pH gradients: Effect of salts, added carrier ampholytes and voltage gradients on protein patterns. Electrophoresis 9: 65–73.
20. Scollay R. (1980). Thymus cell migration: Quantitative aspects of cellular traffic from the thymus to the periphery in mice. Eur. J. Immunol. 10: 210–218.
21. Scollay R., and Godfrey D.I. (1995). Thymic emigration: conveyor belts or lucky dips? Immunol. Today 16: 268–273.
22. Sen J., Shinkai Y., Alt F.W., Sen R., and Burakoff S.J. (1994). Nuclear factors that mediate intrathymic signals are developmentally regulated. J. Exp. Med. 180: 2321–2327.
23. Tough D.F., and Sprent J. (1995). Thymic emigration—A reply. Immunol Today 16: 273–274.
24. Van Ewijk W., Shores E.W., and Singer A. (1994). Crosstalk in the mouse thymus. Immunol. Today 15: 214–217.
25. Xie X., and Palacios R. (1994). Cloning and expression of a new mammalian chaperonin gene from a multipotent hematopoietic progenitor clone. Blood 84: 2171–2174.