Clinical concordance in sibling pairs with multiple sclerosis

Neurology

Volumn 47, Issue 2, 1996, Pages 347-352

  Robertson, N P ^a   Clayton, D ^b   Fraser, M ^a   Deans, J ^a   Compston, D A S ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CLINICAL FEATURE; DEMOGRAPHY; DISABILITY; DISEASE COURSE; FEMALE; GENETIC LINKAGE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIPLE SCLEROSIS; PATIENT COUNSELING; PREVALENCE; PRIORITY JOURNAL; RECURRENCE RISK; SEX RATIO; SIBLING; UNITED KINGDOM;

EID: 0029810384     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/WNL.47.2.347     Document Type: Article

References (23)

1. Ebers GC, Sadovnick AD. The role of genetic factors in multiple sclerosis susceptibility. J Neuroimmunol 1994;54:1-17.
2. Compston DAS. The dissemination of multiple sclerosis. The Langdon Brown Lecture. J R Coll Physicians Lond 1989;24: 207-218.
3. Sadovnick AD, Baird PA, Ward RH. Multiple sclerosis: updated risks for relatives. Am J Med Genet 1988;29:533-541.
4. Mumford CJ, Wood NW, Kellar-Wood H, Thorpe JW, Compston DS. The British Isles survey of multiple sclerosis in twins. Neurology 1994;44:5-11.
5. Bobowick AR, Kurtzke JF, Brody JA, Hrubec Z, Gillespie M. Twin study of multiple sclerosis: an epidemiological enquiry. Neurology 1978;28:978-987.
6. Sadovnick AD, Armstrong H, Rice GPA, et al. A population-based study of multiple sclerosis in twins: update. Ann Neurol 1993;33:281-285.
7. Mumford CJ, Fraser MB, Wood NW, Compston DAS. Multiple sclerosis in the Cambridge Health Authority. J Neurol Neurosurg Psychiatry 1992;55:877-882.
8. Robertson NP, Fraser M, Deans J, Compston DAS. Multiple sclerosis in the north Cambridgeshire districts of East Anglia. J Neurol Neurosurg Psychiatry 1995;59:71-76.
9. Confraveux C, Compston DAS, Hommes OR, MacDonald WI, Thompson AJ. EDMUS, a European database for multiple sclerosis. J Neurol Neurosurg Psychiatry 1992;55:671-676.
10. Poser C, Paty D, Scheinberg L, et al. New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol 1983;13:227-231.
11. Kurtzke JF. Rating neurological impairment in multiple sclerosis: an expanded disability scale status. Neurology 1983;33: 1444-1452.
12. Agresti A. Modelling patterns of agreement and disagreement. Stat Methods Med Res 1992;1:201-218.
13. Rice-Oxley M, Williams ES, Rees JR. A prevalent survey of multiple sclerosis in Sussex. J Neurol Neuorsurg Psychiatry 1995;58:27-30.
14. Swingler RJ, Compston DAS. The prevalence of multiple sclerosis in south east Wales. J Neurol Neurosurg Psychiatry 1988;51:1520-2524.
15. Phadke JG, Downie AW. Epidemiology of multiple sclerosis in northeast (Grampian Region) of Scotland. J Epidemiol Community Health 1987;41:5-13.
16. Doolittle TH, Myers RH, Lehrich JR, et al. Multiple sclerosis sibling pairs: clustered onset and familial predisposition. Neurology 1990;40:937-950.
17. Bulman DE, Sadovnick AD, Ebers GC. Age of onset in sibling pairs concordant for multiple sclerosis. Brain 1991;114:937-950.
18. Koch-Henrikson N. An epidemiological study of multiple sclerosis. Acta Neurol Scand 1989;80Suppl:1-123.
19. Weitkamp LR. Multiple sclerosis susceptibility: interaction between sex and HLA. Arch Neurol 1983;40:399-401.
20. Sadovnick AD, Bulman DE, Hashimoto L, D'Hooghe MB. The influence of gender on the susceptibility to multiple sclerosis in sibships. Arch Neurol 1991;48:586-588.
21. Thompson AJ, Kermode AG, Wicks D, et al. Major differences in the dynamics of primary and secondary progressive multiple sclerosis. Ann Neurol 1991;29:53-62.
22. Olerup O, Hillert J, Fredrikson S, et al. Primarily chronic progressive and relapsing/remitting multiple sclerosis: two immunogenetically distinct disease entities. Proc Natl Acad Sci USA 1989;86:7113-7117.
23. Sadovnick AD. Genetic epidemiology of multiple sclerosis: a survey. Ann Neurol 1994;36:S194-203.