N-(2-hydroxyalkyl)-2,2-dihaloamides by amino-de-alkoxylation of methyl 2,2-dihalocarboxylates

Synthetic Communications

Volumn 26, Issue 19, 1996, Pages 3517-3526

  Forti, Luca ^a   Ghelfi, Franco ^a   Grandi, Romano ^a   Libertini, Emanuela ^a   Pagnoni, Ugo M ^a  

^a UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE; ORGANOCHLORINE DERIVATIVE;

ARTICLE; DRUG SYNTHESIS; REACTION ANALYSIS; TECHNIQUE;

EID: 0029810038     PISSN: 00397911     EISSN: None     Source Type: Journal    
DOI: 10.1080/00397919608003760     Document Type: Article

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46. The basic washing prevented the rearrangement of N-alkyl-N-(2-hydroxyalkyl)-amides alcohols to corresponding ammo esters, which otherwise occurred moderately on standing (in any case N-(2-hydroxyethyl)-N-allyl-2,2-dichloro-hexanamide gave rise to this rearrangement).