Macrophage subtyping in the determination of age of injection sites

International Journal of Legal Medicine

Volumn 109, Issue 1, 1996, Pages 29-33

  Schulz Schaeffer, W J ^a,b   Bruck W ^a   Puschel K ^b  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b UNIVERSITY OF HAMBURG   (Germany)

Author keywords

Drug abuse; Injection lesions; Macrophage differentiation antigen; Macrophage subtyping; Monocyte macrophage system; Wound age

Indexed keywords

ARTICLE; AUTOPSY; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG ABUSE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INJECTION; MACROPHAGE; MONOCYTE; PRIORITY JOURNAL; WOUND;

EID: 0029810008     PISSN: 09379827     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01369598     Document Type: Article

References (29)

1. Akiyama H, Ikeda K, Katoh M, McGeer EG, McGeer PL (1994) Expression of MRP14, 27E10, interferon-alpha and leukocyte common antigen by reactive microglia in postmortem human brain tissue. J Neuroimmunol 50:195-201
2. Althoff H, Schäfer T (1992) Pathomorphologische Venenbefunde bei Drogentoten. Rechtsmedizin 2: 148-151
3. Betz P, Tübel J, Eisenmenger W (1995) Immunohistochemical analysis of markers for different macrophage phenotypes and their use for a forensic wound age estimation. Int J Legal Med 107: 197-200
4. Bhardwaj RS, Zotz C, Zwadlo-Klarwasser G, Roth J, Goebeler M, Mahnke K, Falk M, Meinardus-Hager G, Sorg C (1992) The calcium-binding proteins MRP8 and MRP14 form a membrane-associated heterodimer in a subset of monocytes/ macrophages present in acute but absent in chronic inflammatory lesions. Eur J Immunol 22: 1891-1897
5. Boenisch T (1989) Staining methods. In: Naish SJ (ed) Handbook - Immunochemical staining methods. Dako, Carpinteria, Calif., pp 22-27
6. Boltz W (1951) Histologische Untersuchungen an Injektionsstichspuren. Dtsch Z Gerichtl Med 40: 181-191
7. Edgeworth J, Gorman M, Bennett R, Freemont P, Hogg N (1991) Identification of p8,14 as a highly abundant heterodimeric calcium binding protein complex of myeloid cells. J Biol Chem 266:7706-7713
8. Friebel L, Woohsmann H (1968) Die Altersbestimmung von Kanülenstichen mittels enzymhistochemischer Methoden. Dtsch Z Gerichtl Med 62:252-260
9. Gerlach D (1977) Identifizierung und Altersbestimmung von Nadelstichverletzungen in der menschlichen Haut. Z Rechtsmed 79: 289-295
10. Gerlach D (1978) Histopathologische Befunde bei Rauschmittelkonsumenten. Z Rechtsmed 80: 299-304
11. Goebler M, Roth J, Teigelkamp S, Sorg C (1994) The monoclonal antibody MAC387 detects an epitope on the calcium-binding protein MRP14. J Leukoc Biol 55:259-261
12. 2+-binding proteins of neutrophils and monocytes. J Leukoc Biol 53:197-204
13. Hirsch CS (1972) Dermatopathology of narcotic addiction. Hum Pathol 3:37-53
14. Janssen W (1993) Pathological findings in drug deaths. In: Palmieri L (ed) Atti del Convegno su "I rilievi anatomo-istologici nella diagnosi medico-legale della morte da overdose di sostanze stupefacenti". Med Leg Quad Cam XII (n 2), pp 159-173
15. Karch SB (ed) (1993) Dermatologic sequelae of opiate abuse. In: The pathology of drug abuse. CRC, Boca Raton, Fia, pp 293-300
16. Kellner G, Feucht G (1969) Die Mikrowunde (mikroskopische Studie des Nadelstichs). Phys Med Rehab 10:218-220
17. Kringsholm B (1993) Histological evidence in fatal drug addiction. In: Palmitieri L (ed) Atti del Convegno su "I rilievi anatomo-istologici nella diagnosi medico-legale della morte da overdose di sostanze stupefacenti". Med Leg Quad Cam XII (n 2), pp 175-192
18. Kringsholm B, Christoffersen P (1989) Morphological findings in fatal drug addiction. An investigation of injection marks, endocrine organs and kidney. Forensic Sci Int 40:15-24
19. Odnik K, Cerletti N, Brüggen J, Clerc RG, Tarcsay L, Zwadlo G, Gerhards G, Schlegel R, Sorg C (1987) Two calcium-binding proteins in infiltrate macrophages of rheumatoid arthritis. Nature 330:80-82
20. Oehmichen M (1990) Die Wundheilung. Theorie und Praxis der Chronomorphologie in der forensischen Pathologie. Springer, Berlin Heidelberg New York
21. O'Laughlin S, Braverman M, Smith-Jefferies M, Buckley P (1992) Macrophages (histiocytes) in various reactive and inflammatory conditions express different antigenic phenotypes. Hum Pathol 23:1410-1418
22. Ozawa K, Suchanek G, Breitschopf H, Brück W, Budka H, Jellinger K, Lassmann H (1994) Patterns of oligodendroglia pathology in multiple sclerosis. Brain 117:1311-1322
23. Radzun HJ, Hansmann M-L, Heidebrecht HJ, Bödewald-Radzun S, Wacker HH, Kreipe H, Lumbeck H, Hernandez C, Kuhn C, Parwaresch MR (1991) Detection of a monocyte/macrophage differentiation antigen in routinely processed paraffin-embedded tissues by monoclonal antibody Ki-M1P. Lab Invest 65: 306-315
24. Schollmeyer W (1965) Über die Altersbestimmung von Injektionsstichen. Beitr Gerichtl Med 23: 244-249
25. Sorg C (ed) (1988) Macrophages in inflammation. In: The alveolar macrophage. Regensberg and Biermann, Dortmund, pp 23-35
26. Teigelkamp S, Bhardwaj RS, Roth J, Meinardus-Hager G, Karas M, Sorg C (1991) Calcium-dependent complex assembly of the myeloic differentiation proteins MRP8 and MRP14. J Biol Chem 266:13462-13467
27. Zwadlo G, Bröcker E-B, von Bassewitz D-B, Feige U, Sorg C (1985) A monoclonal antibody to a differentiation antigen present on mature human macrophages and absent from monocytes. J Immunol 134:1487-1493
28. Zwadlo G, Schlegel R, Sorg C (1986) A monoclonal antibody to a subset of human monocytes found only in the peripheral blood and inflammatory tissues. J Immunol 137:512-518
29. Zwadlo G, Brüggen J, Gerhards G, Schlegel R, Sorg C (1988) Two calcium-binding proteins associated with specific stages of myeloid cell differentiation are expressed by subsets of macrophages in inflammatory tissues. Clin Exp Immunol 72: 510-515