Synthesis and pharmacological properties of 4(5)-(2-ethyl-2,3-dihydro-2-silainden-2-yl)imidazole, a silicon analogue of atipamezole

European Journal of Medicinal Chemistry

Volumn 31, Issue 9, 1996, Pages 725-729

  Heinonen, P ^a   Sipila H ^b   Neuvonen, K ^a   Lonnberg H ^a   Cockcroft, V B ^c   Wurster, S ^c   Virtanen, R ^c   Savola, M K T ^c   Salonen, J S ^d   Savola, J M ^c  

^a UNIVERSITY OF TURKU   (Finland)

^b TURKU PET CENTRE   (Finland)

^c ORION CORPORATION   (Finland)

^d NONE

Author keywords

Adrenergic receptor; Atipamezole; Grignard reaction; Semi empirical calculation; Silaindane

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR; ALPHA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; ATIPAMEZOLE; IMIDAZOLE DERIVATIVE; RAUWOLSCINE; RECEPTOR SUBTYPE;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCULATION; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; ELECTROSTIMULATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IN VITRO STUDY; INTRAVENOUS DRUG ADMINISTRATION; MALE; MOLECULAR MODEL; MYDRIASIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PKA; RAT; SUBCUTANEOUS DRUG ADMINISTRATION; VAS DEFERENS;

EID: 0029810006     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/0223-5234(96)85882-X     Document Type: Article

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