Enhancement by calcitonin gene-related peptide of noncontractile Ca2+-induced nicotinic receptor desensitization at the mouse neuromuscular junction

British Journal of Pharmacology

Volumn 118, Issue 8, 1996, Pages 1971-1976

  Dezaki, Katsuya ^a   Kimura, Ikuko ^a   Tsuneki, Hiroshi ^a   Kimura, Masayasu ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

Author keywords

Calcitonin gene related peptide; Desensitization; Neuromuscular postsynapse; Nicotinic acetylcholine receptor; Non contractile calcium; Protein kinase A; Protein kinase C

Indexed keywords

AEQUORIN; CALCITONIN GENE RELATED PEPTIDE; CALCIUM ION; CYCLIC AMP DEPENDENT PROTEIN KINASE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; NEOSTIGMINE; NICOTINIC RECEPTOR; PROTEIN KINASE INHIBITOR;

ANIMAL TISSUE; ARTICLE; CALCIUM MOBILIZATION; CONTROLLED STUDY; DIAPHRAGM MUSCLE; ENZYME ACTIVATION; LUMINESCENCE; MALE; MOUSE; MUSCLE CONTRACTION; NEUROMUSCULAR SYNAPSE; NONHUMAN; PHRENIC NERVE; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION;

EID: 0029809083     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1996.tb15632.x     Document Type: Article

References (33)

1. ALBUQUERQUE, E.X., DESHPANDE, S.S., ARACAVA, Y., ALKONDON, M. & DALY, J.W. (1986). A possible involvement of cyclic AMP in the expression of desensitization of the nicotinic acetylcholine receptor. FEBS Lett., 199, 113-120.
2. CHIJIWA, T., MISHIMA, A., HAGIWARA, M., SANO, M., HAYASHI, K., NAITO, K., TOSHIOKA, T. & HIDAKA, H. (1990). Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide (H-89), of PC12D pheochromocytoma cells. J. Biol. Chem., 265, 5267-5272.
3. EUSEBI, F., GRASSI, F., NERVI, C., CAPORALE, C., ADAMO, S., ZANI, B.M. & MOLINARO, M. (1987). Acetylcholine may regulate its own nicotinic receptor-channel through the C-kinase system. Proc. R. Soc. Lond. B, 230, 355-365.
4. FERRER-MONTIEL, A.V., MONTAL, M.S., DIAZ-MUNOZ, M. & MONTAL, M. (1991). Agonist-independent activation of acetylcholine receptor channels by protein kinase A phosphorylation. Proc. Natl. Acad. Sci. U.S.A., 88, 10213-10217.
5. FONTAINE, B., KLARSFELD, A., HOKFELT, T. & CHANGEUX, J.-P. (1986). Calcitonin gene-related peptide, a peptide present in spinal cord motoneurons, increases the number of acetylcholine receptors in primary cultures of chick embryo myotubes. Neurosci. Lett., 71, 59-65.
6. HOPFIELD, J.F., TANK, D.W., GREENGARD, P. & HUGANIR, R.L. (1988). Functional modulation of the nicotinic acetylcholine receptor by tyrosine phosphorylation. Nature, 336, 677-680.
7. HUGANIR, R.L., DELCOUR, A.H., GREENGARD, P. & HESS, G.P. (1986). Phosphorylation of the nicotinic acetylcholine receptor regulates its rate of desensitization. Nature, 321, 774-776.
8. HUGANIR, R.L. & GREENGARD, P. (1983). cAMP-dependent protein kinase phosphorylates the nicotinic acetylcholine receptor. Proc. Natl. Acad. Sci. U.S.A., 80, 1130-1134.
9. JENNINGS, C.G.B. & MUDGE, A.W. (1989). Chick myotubes in culture express high-affinity receptors for calcitonin gene-related peptide. Brain Res., 504, 199-205.
10. 2+ mobilization via protein kinase-C activation at the mouse neuromuscular junction. Br. J. Pharmacol., 114, 461-467.
11. 2+ transients with neostigmine in phrenic nerve-diaphragm muscles of mice. Brain Res., 507, 309-311.
12. 2+ produced in the mouse diaphragm by neuromuscular blocking drugs. J. Pharm. Pharmacol., 42, 626-631.
13. 2+ mobilization operated by acetylcholine receptor in mouse diaphragm muscle. Neurosci. Lett., 127, 28-30.
14. 2+ mobilization at the mouse neuromuscular junction. Br. J. Pharmacol., 110, 639-644.
15. KIMURA, M., KIMURA, I. & KOBAYASHI, S. (1977). The activation of cyclic 3′, 5′-adenosine monophosphate-dependent protein kinase on sarcoplasmic reticulum fractions of various smooth muscles and its related novel relaxants. Biochem. Pharmacol., 26, 994-996.
16. ++ mobilization: Suppression of activation by open channel blockers and acceleration of desensitization by closed channel blockers in mouse diaphragm muscle. J. Pharmacol. Exp. Ther., 256, 18-23.
17. KOBAYASHI, H., HASHIMOTO, K., UCHIDA, S., SAKUMA, J., TAKAMI, K., TOHYAMA, M., IZUMI, F. & YOSHIDA, H. (1987). Calcitonin gene-related peptide stimulates adenylate cyclase activity in rat striated muscle. Experientia, 43, 314-316.
18. LU, B., FU, W., GREENGARD, P. & POO, M.-M. (1993). Calcitonin gene-related peptide potentiates synaptic responses at developing neuromuscular junction. Nature, 363, 76-79.
19. MAGLEBY, K. L. & PALLOTTA, B.S. (1981). A study of desensitization of acetylcholine receptors using nerve-released transmitter in the frog. J. Physiol., 316, 225-250.
20. MATSUMOTO, N., WANG, X.-B. & UCHIDA, S. (1992). Different natures of supersensitivity of adenylate cyclase stimulated by calcitonin gene-related peptide and isoproterenol in rat diaphragm after denervation and reserpine treatment. J. Neurochem., 58, 357-361.
21. MATTEOLI, M., HAIMANN, C., TORRI-TARELLI, F., POLAK, J.M., CECCARELLI, B. & DE CAMILLI, P. (1988). Differential effect of α-latrotoxin on exocytosis from small synaptic vesicles and from large dense-core vesicles containing calcitonin gene-related peptide at the frog neuromuscular junction. Proc. Natl. Acad. Sci. U.S.A., 85, 7366-7370.
22. MIDDLETON, P., RUBIN, L.L. & SCHUETZE, S.M. (1988). Desensitization of acetylcholine receptors in rat myotubes is enhanced by agents that elevate intracellular cAMP. J. Neurosci., 8, 3405-3412.
23. MILEDI, R. (1980). Intracellular calcium and desensitization of acetylcholine receptors. Proc. R. Soc. Lond. B, 209, 447-452.
24. MILES, K., GREENGARD, P. & HUGANIR, R.L. (1989). Calcitonin gene-related peptide regulates phosphorylation of the nicotinic acetylcholine receptor in rat myotubes. Neuron, 2, 1517-1524.
25. MULLE, C., BENOIT, P., PINSET, C., ROA, M. & CHANGEUX, J.-P. (1988). Calcitoningene-related peptide enhances the rate of desensitization of the nicotinic acetylcholine receptor in cultured mouse muscle cells. Proc. Natl. Acad. Sci. U.S.A., 85, 5728-5732.
26. NEW, H.V. & MUDGE, A.W. (1986). Calcitonin gene-related peptide regulates muscle acetylcholine receptor synthesis. Nature, 323, 809-811.
27. NOJIMA, H., KIMURA, I. & KIMURA, M. (1994). The evidence of accelerative interaction between cAMP-dependent protein kinase and external calcium for the desensitization of nicotinic acetylcholine receptor channel in mouse skeletal muscle cells. Neurosci. Lett., 167, 113-116.
28. OWENS, J.L. & KULLBERG, R.W. (1993). Calcitonin gene-related peptide lengthens actylcholine receptor channel open time in developing muscle. Receptors and Channels, 1, 165-171.
29. POPER, P. & MICEVYCH, P.E. (1989). Localization of calcitonin generelated peptide and its receptors in a striated muscle. Brain Res., 496, 180-186.
30. ROA, M. & CHANGEUX, J.-P. (1991). Characterization and developmental evolution of a high-affinity binding site for calcitonin gene-related peptide on chick skeletal muscle membrane. Neuroscience, 41, 563-570.
31. TAKAMI, K., KAWAI, Y., SHIOSAKA, S., LEE, Y., GIRGIS, S., HILLYARD, C.J., NACINTYRE, I., EMSON, P.C. & TOHYAMA, M. (1985a). Immunohistochemical evidence for the coexistence of calcitonin gene-related peptide- and choline acetyltransferaselike immunoreactivity in neurons of the rat hypoglossal, facial and ambiguus nuclei. Brain Res., 328, 386-389.
32. TAKAMI, K., KAWAI, Y., UCHIDA, S., TOHYAMA, M., SHIOTANI, Y., YOSHIDA, H., EMSON, P.C., GIRGIS, S., HILLYARD, C.J. & MACINTIRE, I. (1985b). Effect of calcitonin gene-related peptide on concentration of striated muscle in the mouse. Neurosci. Lett., 60, 227-230.
33. WAGONER, P.K. & PALLOTTA, B.S. (1988). Modulation of acetylcholine receptor desensitization by forskolin is independent of cAMP. Science, 240, 1655-1657.