PhhR, a divergently transcribed activator of the phenylalanine hydroxylase gene cluster of Pseudomonas aeruginosa

Molecular Microbiology

Volumn 22, Issue 3, 1996, Pages 497-507

  Song, Jian ^a   Jensen, Roy A ^a  

^a UNIVERSITY OF FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PHENYLALANINE 4 MONOOXYGENASE; TRANSCRIPTION FACTOR;

ARTICLE; CONTROLLED STUDY; DNA SEQUENCE; GENE CLUSTER; NONHUMAN; OPERON; PRIORITY JOURNAL; PROMOTER REGION; PSEUDOMONAS AERUGINOSA; TRANSCRIPTION REGULATION;

ESCHERICHIA COLI; HAEMOPHILUS INFLUENZAE; PROKARYOTA; PSEUDOMONAS; PSEUDOMONAS AERUGINOSA;

EID: 0029808625     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.1996.00131.x     Document Type: Article

References (38)

1. Argaet, V.P., Wilson, T.J., and Davidson, B.E. (1994) Purification of the Escherichia coli regulatory protein TyrR and analysis of its interactions with ATP, tyrosine, phenylalanine and tryptophan. J Biol Chem 269: 5171-5178.
2. Baldwin, G.S., and Davidson, B.E. (1981) A kinetic and structural comparison of chorismate mutase/prephenate dehydratase from mutant strains of Escherichia coli K-12 defective in the pheA gene. Arch Biochem Biophys 211: 66-75.
3. Camakaris, H., and Pittard, J. (1973) Regulation of tyrosine and phenylalanine biosynthesis in Escherichia coli K-12: properties of the tyrR gene product. J Bacteriol 115: 1135-1144.
4. Canellakis, E.S., Paterakis, A.A., Huang, S.-C., Panagiotidis, C.A., and Kyriakidis, D.A. (1993) Identification, cloning, and nucleotide sequencing of the ornithine decarboxylase antizyme gene of Escherichia coli. Proc Natl Acad Sci USA 90: 7129-7133.
5. Chang, A.C.Y., and Cohen, S.N. (1978) Construction and characterization of amplifiable multicopy DNA cloning vehicles derived from the p15A cryptic miniplasmid. J Bacteriol 134: 1141-1156.
6. Cui, J., and Somerville, R.L. (1993) The TyrR protein of Escherichia coli, analysis by limited proteolysis of domain structural and ligand-mediated conformational changes. J Biol Chem 268: 5040-5047.
7. DeFeyter, R., Kado, C.I., and Gabriel, D.W. (1990) Small, stable shuttle vectors for use in Xanthomonas. Gene 88: 65-72.
8. Devereux, J., Haeberli, P., and Smithies, O. (1984) A comprehensive set of sequence analysis programs for the VAX. Nucl Acids Res 12: 387-395.
9. Essar, D.W., Eberly, L., Han, C.-Y., and Crawford, I.P. (1990) DNA sequences and characterization of four early genes of the tryptophan pathway in Pseudomonas aeruginosa. J Bacteriol 172: 853-866.
10. Friedman, D.I. (1988) Integration host factor: a protein for all reasons. Cell 55: 545-554.
11. Gambill, D.B., and Summers, A.O. (1985) Versatile mercury-resistant cloning and expression vectors. Gene 39: 293-297.
12. Heatwole, V.M., and Somerville, R.L (1991) The tryptophan-specific permease gene, mtr, is differentially regulated by the tryptophan and tyrosine repressors in Escherichia coli K-12. J Bacteriol 173: 3601-3604.
13. Holloway, B.W. (1955) Genetic recombination in Pseudomonas aeruginosa. J Gen Microbiol 13: 572-581.
14. Ivey-Hoyle, M., and Steege, D.A. (1992) Mutational analysis of an inherently defective translation initiation site. J Mol Biol 224: 1039-1054.
15. Jensen, R.A., and Gu, W. (1996) Evolutionary recruitment of biochemically specialized subdivisions of Family I within the protein Superfamily of aminotransferases. J Bacteriol 178: 2161-2171.
16. Joerger, R.D., Jacobson, M.R., and Bishop, P.E. (1989) Two nifA-like genes required for expression of alternative nitrogenases by Azotobacter vinelandii. J Bacteriol 171: 3258-3267.
17. 70 promoters. Mol Microbiol 17: 471-481.
18. Laemmli, U.K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685.
19. Miller, J.H. (1972) Experiments in Molecular Genetics. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press.
20. Morrett, E., and Segovia, L. (1993) The bacterial enhancer-binding protein family: mechanism of action and phylogenetic relationship of their functional domains. J Bacteriol 175: 6067-6074.
21. Nakata, H., Yamauchi, T., and Fujisawa, H. (1979) Phenylalanine hydroxylase from Chromobacterium violaceum: purification and characterization. J Biol Chem 266: 18454-18459.
22. Patel, N., Stenmark-Cox, S., and Jensen, R.A. (1978) Enzymological basis of reluctant auxotrophy for phenylalanine and tyrosine in Pseudomonas aeruginosa. J Biol Chem 253: 2972-2978.
23. Pittard, A.J. (1996) Biosynthesis of the aromatic amino acids. In Escherichia coli and Salmonella. Neidhardt, F.C. (ed.). Washington, DC: American Society for Microbiology, pp. 458-484.
24. Pittard, A.J., and Davidson, B.E. (1991) TyrR protein of Escherichia coli and its role as repressor and activator. Mol Microbiol 5: 1585-1592.
25. Rosentel, J.K., Healy, F., Maupin-Furlow, J.A., Lee, J.H., and Shanmugam, K.T. (1995) Molybdate and regulation of mod (molybdate transport), fdhF, and hyc (formate hydrogenlyase) operons in Escherichia coli. J Bacteriol 177: 4857-4864.
26. Sambrook, J., Fritsch, E.F., and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual, 2nd edn. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press.
27. Schweizer, H.P. (1993) Two plasmids, X1918 and Z1918, for easy recovery of the xylE and lacZ reporter genes. Gene 134: 89-91.
28. 54-dependent reulators: derepression as a control mechanism. Mol Microbiol 19: 409-416.
29. Simon, R., Priefer, U., and Pühler, A. (1983) A broad host range mobilization system for in vivo genetic engineering: transposon mutagenesis in gram negative bacteria. Biol Technology 1: 784-791.
30. Simons, R.W., Houman, F., and Kleckner, N. (1987) Improved single and multicopy lac-based cloning vectors for protein and operon fusions. Gene 53: 85-96.
31. Stock, J.B., Ninfa, A.J., and Stock, A.M. (1989) Protein phosphorylation and regulation of adaptive responses in bacteria. Microbiol Rev 53: 450-490.
32. Totten, P.A., Lara, J.C., and Lory, S. (1990) The rpoN gene product of Pseudomonas aeruginosa is required for expression of diverse genes, including the flagellin gene. J Bacteriol 172: 389-396.
33. Towbin, H, Staehelin, T., and Gordon, J. (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 76: 4350-4354.
34. Xia, T., and Jensen, R.A. (1990) A single cyclohexadienyl dehydrogenase specifies the prephenate dehydrogenase and arogenate dehydrogenase components of the dual pathways to L-tyrosine in Pseudomonas aeruginosa. J Biol Chem 265: 200333-20036.
35. Yang, J., Ganesan, S., Sarsero, J., and Pittard, A.J. (1993) A genetic analysis of various functions of the TyrR protein of Escherichia coli. J Bacteriol 175: 1767-1776.
36. Yanisch-Perron, C., Vieira, J., and Messing, J. (1985) Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC vectors. Gene 33: 103-119.
37. Zhao, G., Xia, T., Aldrich, H., and Jensen, R.A. (1993) Cyclohexadienyl dehydratase from Pseudomonas aeruginosa is a periplasmic protein. J Gen Microbiol 139: 807-813.
38. Zhao, G., Xia, T., Song, J., and Jensen, R.A. (1994) Pseudomonas aeruginosa possesses homologues of mammalian phenylalanine hydroxylase and 4a-carbinolamine dehydratase/DCoH as part of a three-component gene cluster. Proc Natl Acad Sci USA 91: 1366-1370.