Sonic hedgehog in feather morphogenesis: Induction of mesenchymal condensation and association with cell death

Developmental Dynamics

Volumn 207, Issue 2, 1996, Pages 157-170

  Ting Berreth, Sheree A ^a   Chuong, Cheng Ming ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Cell death; Epithelial mesenchymal interaction; Feather; Hair; Morphogenesis; Pattern formation; Retroviral gene delivery; Scaleless; Skin appendage

Indexed keywords

VIRUS VECTOR;

ACTIN MYOSIN INTERACTION; ANIMAL CELL; ARTICLE; CELL DEATH; CELL POLARITY; CHO CELL; EMBRYO PATTERN FORMATION; EPITHELIUM CELL; FEATHER; GENE TARGETING; MESENCHYME; MORPHOGENESIS; NONHUMAN; PRIORITY JOURNAL; SKIN APPENDAGE;

ANIMALS; CELL DEATH; CHICK EMBRYO; EPITHELIUM; FEATHERS; HEDGEHOG PROTEINS; MESODERM; MORPHOGENESIS; NEURAL CELL ADHESION MOLECULES; PROTEIN KINASE C; PROTEINS; RECOMBINANT FUSION PROTEINS; TENASCIN; TRANS-ACTIVATORS; TRANSFORMING GROWTH FACTOR BETA;

ANIMALIA; ERINACEIDAE; VERTEBRATA;

EID: 0029808529     PISSN: 10588388     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0177(199610)207:2<157::AID-AJA4>3.0.CO;2-G     Document Type: Article

References (37)

1. Abbott, U.K., and Asmundson, V.S. (1957) Scaleless, an inherited ectodermal defect in the domestic fowl. J. Hered. 48:63-70.
2. Bitgood, M.J., and McMahon, A.P. (1995) Hedgehog and BMP genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo. Dev. Biol. 172:126-138.
3. Chang, D.T., Lopez, A., von Kessler, D.P., Chiang, C., Simandl, B.K., Zhao, R., Seldin, M.F., Fallon, J.F., and Beachy, A. (1994) Products, genetic linkage and limb patterning activity of a murine hedgehog gene. Development 120:3339-3353.
4. Chuong, C.-M., Oliver, G., Ting, S.A., Jegalian, B.G., Chen, H.-M., and De Robertis, E.M. (1990) Gradients of homeoproteins in developing feather buds. Development 110:1021-1030.
5. Chuong, C.-M. (1993) The making of a feather: Homeoproteins and retinoids and adhesion molecules. Bioessays 15:513-521.
6. Chuong, C.-M., and Edelman, G.M. (1985a) Expression of cell-adhesion molecules in embryonic induction. I. Morphogenesis of nestling feathers. J. Cell Biol. 101:1009-1026.
7. Chuong, C.-M., and Edelman, G.M. (1985b) Expression of cell adhesion molecules in embryonic induction. II. Morphogenesis of adult feathers. J. Cell Biol. 101:1027-1043.
8. Echelard, Y., Epstein, D.J., St.-Jacques, B., Shen, L., Mohler, J., McMahon, J.A., and McMahon, A.P. (1993) Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity. Cell 75:1417-1430.
9. Fan, C.-M., and Tessier-Lavigne, M. (1994) Patterning of mammalian somites by surface ectoderm and notochord: Evidence for sclerotome induction by a hedgehog homolog. Cell 79:1175-1186.
10. Fan, C.-M., Porter, J.A., Chiang, C., Chang, D.T., Beachy, P.A., and Tessier-Lavigne, M. (1995) Long-range sclerotome induction by Sonic hedgehog: Direct role of the amino-terminal cleavage product and modulation by the cyclic AMP signaling pathway. Cell 81:457-465.
11. Fekete, D., and Cepko, C. (1993) Replication-competent retroviral vectors encoding alkaline phosphatase reveal spatial restriction of viral gene expression/transduction in the chick embryo. Mol. Cell Biol. 13:2604-2613.
12. Hamburger, V., and Hamilton, H. (1951) A series of normal stages in the development of the chick embryo. J. Morphol. 88:49-92.
13. Jiang, T.-X., and Chuong, C.-M. (1992) Mechanism of feather morphogenesis: I. Analyses with antibodies to adhesion molecules tenascin, N-CAM and integrin. Dev. Biol. 150:82-98.
14. Johnson, R.L., and Tabin, C. (1995) The long and short of hedgehog signaling. Cell 81:313-316.
15. Johnson, R.L., Laufer, E., Riddle, R.D., and Tabin, C. (1994) Ectopic expression of Sonic hedgehog alters dorsal-ventral patterning of somites. Cell 79:1165-1173.
16. Krauss, S., Concordet, J.P., and Ingham, P.W. (1993) A functionally conserved homolog of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish embryos. Cell 75:1431-1444.
17. Lee, J.J., Ekker, S.C., von Kessler, D.P., Porter, J.A., Sun, B.I., and Beachy, P.A. (1994) Autoproteolysis in hedgehog protein biogenesis. Science 266:1528-1537.
18. Lucas, A.M., and Stettenheim, P.R. (1972) Avian anatomy. Integument. In: "Agriculture Handbook 362." Washington, DC: Agricultural Research Services, U.S. Department of Agriculture.
19. McAleese, S.R., and Sawyer, R.H. (1981) Correcting the phenotype of the epidermis from chick embryos homozygous for the gene scaleless (sc/sc). Science 214:1033-1034.
20. Morgan, B.A., Izpisua-Belmonte, J.-C., Duboule, D., and Tabin, C.J. (1992) Targeted misexpression of Hox-4.6 in the avian limb bud causes apparent homeotic transformation. Nature 358:236-239.
21. Nohno, T., Kawakami, Y., Ohuchi, H., Fujiwara, A., Yoshioka, H., and Noji, S. (1995) Involvement of the Sonic hedgehog gene in chick feather development. Biochem. Biophys. Res. Commun. 206:33-39.
22. Noveen, A., Jiang, T.-X., Ting-Berreth, S.A., and Chuong, C.-M. (1995a) Homeobox genes Msx-1 and Msx-2 are associated with induction and growth of skin appendages. J. Invest. Dermatol. 104: 711-719.
23. Noveen, A., Jiang, T.-X., and Chuong, C.-M. (1995b) Protein kinase A and protein kinase C modulators have reciprocal effects on mesenchymal condensation during skin appendage morphogenesis. Dev. Biol. 171:677-693.
24. Novel, G. (1973) Feather pattern stability and reorganization in cultured skin. J. Embryol. Exp. Morphol. 30:605-633.
25. Placzek, M., Tessier-Lavigne, M., Yamamda, T., Jessell, T.M., and Dodd, J. (1990) Mesodermal control of the neural cell identity: Floor plate induction by the notochord. Science 250:985-988.
26. Porter, J.A., Ekker, S.C., Young, K.E., von Kessler, D.P., Lee, J.J., Moses, K., and Beachy, P.A. (1995) The product of hedgehog autoproteolytic cleavage active in local and long-range signalling. Nature 374:363-366.
27. Riddle, R.D., Johnson, R.L., Laufer, E., and Tabin, C. (1993) Sonic hedgehog mediates the polarizing activity of the ZPA. Cell 75:1401-1416.
28. Roelink, H., Augsburger, A., Heemskerk, J., Korzh, V., Norlin, S., Ruiz i Altaba, A., Tanabe, Y., Placzek, M., Edlund, T., Jessell, T.M., and Dodd, J. (1994) Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord. Cell 76:761-775.
29. Roelink, H., Porter, J.A., Chiang, C., Tanabe, Y., Chang, D.T., Beachy, P.A., and Jessell, T.M. (1995) Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of Sonic hedgehog autoproteolysis. Cell 81:445-455.
30. Sasaki, H., and Hogan, B.L. (1993) Differential expression of multiple fork head related genes during gastrulation and axial pattern formation in the mouse embryo. Development 118:47-59.
31. Sawyer, R.H., and Fallon, J.F. (eds.; 1983) "Epithelial-Mesenchymal Interactions in Development." New York: Praeger Publishing.
32. Sengel, P. (1976) "Morphogenesis of Skin." Abercrombie, M., Newth, D.R., and Torrey, J.G. (eds). Cambridge: Cambridge University Press.
33. Sengel, P. (1978) Feather pattern development. Ciba Found. Symp. 29:51-70.
34. Sengel, P., and Abbott, U.K. (1963) In vitro studies with the scaleless mutant: Interaction during feather and scale differentiation. J. Hered. 54:254-262.
35. van Straaten, H.M.W., Hekking, J.M.W., Wiertz-Hoessells, E.L., Thors, F., and Drukker, J. (1988) Effect of the notochord on the differentiation of a floor plate area in the neural tube of the chick embryo. Anat. Embryol. 177:317-324.
36. Wessels, N.K. (1965) Morphology and proliferation during early feather development. Dev. Biol. 12:131-153.
37. Widelitz, R.B., Jiang, T.-X., Noveen, A., Ting-Berreth, S.A., Yin, E., and Chuong, C.-M. (1996) Molecular histology in skin appendage morphogenesis. Microsc. Res. Tech. (in press).