Marine natural products. XXXVII. Aragusteroketals A and C, two novel cytotoxic steroids from a marine sponge of Xestospongia sp.

Chemical and Pharmaceutical Bulletin

Volumn 44, Issue 10, 1996, Pages 1840-1842

  Kobayashi, Motomasa ^a   Chen, Yin Ju ^a   Higuchi, Kouichi ^a   Aoki, Shunji ^a   Kitagawa, Isao ^a,b  

^a OSAKA UNIVERSITY   (Japan)

^b KINKI UNIVERSITY   (Japan)

Author keywords

cytotoxic; dimethylketal; marine sponge; steroid; Xestospongia

Indexed keywords

ANTINEOPLASTIC AGENT; ARAGUSTEROKETAL A; ARAGUSTEROKETAL C; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL PROLIFERATION; DOSE RESPONSE; DRUG CONFORMATION; DRUG ISOLATION; DRUG POTENCY; DRUG SYNTHESIS; GROWTH INHIBITION; HUMAN; HUMAN CELL; SPONGE (PORIFERA); STRUCTURE ACTIVITY RELATION;

EID: 0029807795     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.44.1840     Document Type: Article

References (5)

1. Part XXXV: Kobayashi M., Chen Y., Aoki S., In Y., Ishida T., Kitagawa I., Tetrahedron, 51, 3727-3736 (1995).
2. Iguchi K., Fujita M., Nagaoka H., Mitome H., Yamada Y., Tetrahedron Lett., 34, 6277-6280 (1993).
3. Shimura H., Iguchi K., Yamada Y., Nakaike S., Yamagishi T., Matsumoto K., Yokoo C., Experientia, 50, 134-136 (1994).
4. Iguchi K., Shimura H., Taira S., Yokoo C., Matsumoto K., Yamada Y., J. Org. Chem., 59, 7499-7502 (1994).
5. Kobayashi J., Ishida K., Naitoh K., Shigemori H., J. Nat. Prod., 56, 1350-1355 (1993). Xestokerol C seems to be identical with aragusterol D.