Estrogen receptor-immunoreactive neurons are present in the female rat lumbosacral spinal cord

Journal of Neuroscience Research

Volumn 46, Issue 4, 1996, Pages 492-501

  Williams, Sonya J ^a   Papka, Raymond E ^a  

^a UNIVERSITY OF OKLAHOMA   (United States)

Author keywords

estrogen receptor; FOS; nitric oxide; reproduction; sacral parasympathetic nucleus

Indexed keywords

ESTROGEN RECEPTOR; NITRIC OXIDE;

ARTICLE; ESTRADIOL BLOOD LEVEL; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LUMBOSACRAL SPINE; PARASYMPATHETIC GANGLION; PARASYMPATHETIC INNERVATION; PRIORITY JOURNAL; RECEPTOR BINDING; REPRODUCTION; SEXUAL BEHAVIOR; SPINAL CORD;

ANIMALS; CERVIX UTERI; FEMALE; GENE EXPRESSION REGULATION; LUMBOSACRAL REGION; NADPH DEHYDROGENASE; NERVE TISSUE PROTEINS; NEURONS; NITRIC OXIDE; OVARIECTOMY; POSTURE; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ESTROGEN; SEXUAL BEHAVIOR, ANIMAL; SPINAL CORD; UTERUS;

EID: 0029807718     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19961115)46:4<492::AID-JNR11>3.0.CO;2-0     Document Type: Article

References (50)

1. Abercrombie M (1946): Estimation of nuclear population from microtome sections. Anat Rec 94:239-247.
2. Amandusson A, Hermanson O, Blomqvist A (1995): Estrogen receptor-like immunoreactivity in the medullary and spinal dorsal horn of the female rat. Neurosci Lett 196:25-28.
3. Berkley KJ, Robbins A, Sato Y (1988): Afferent fibers supplying the uterus in the rat. J Neurophysiol 59:142-163.
4. Berkley KJ, Hubscher CH, Wall PD (1993a): Neuronal responses to stimulation of the cervix, uterus, colon, and skin in the rat spinal cord. J Neurophysiol 69:545-556.
5. Berkley KJ, Robbins A, Sato Y (1993b): Functional differences between afferent fibers in the hypogastric and pelvic nerves innervating female reproductive organs in the rat. J Neurophysiol 69:533-544.
6. Blaustein JF, Dudley SD, Gray JM, Roy EJ, ON Wade (1979): Long term retention of estradiol by brain cell nuclei and female rat sexual behavior. Brain Res 173:355-359.
7. Boling JL, Blandau RJ (1939): Estrogen-progesterone induction of mating responses in spayed female rat. Endocrinology 25:359-364.
8. Burstein R, differ KD, Geisler GJ (1990a): Cells of origin of the spinohypothalamic tract in the rat. J Comp Neurol 291:329-344.
9. Burstein R, Wang J, Elde RP, Giesler GJ (1990b): Neurons in the sacral parasympathetic nucleus that project to the hypothalamus do not also project through the pelvic nerve - a double labeling study combining fluoro-gold and cholera toxin B in the rat. Brain Res 506:159-165.
10. Chinapen S, Swann JM, Steinman JL, Komisaruk BR (1992): Expression of c-fos protein in lumbosacral spinal cord in response to vaginocervical stimulation in rats. Neurosci Lett 145:93-96.
11. Dellovade TL, Baulstein JD, Rissman EF (1992): Neural distribution of estrogen receptor immunoreactive cells in the female musk shrew. Brain Res 595:189-194.
12. Deville Y, Blaustein JD (1993): Estrogen receptor-immunoreactive forebrain neurons project to the ventrolateral hypothalamus in female guinea pigs. J Comp Neurol 334:571-589.
13. Giesler GJ, Cannon JT, Urea G, Liebeskind GC (1978): Long ascending projections from substantia gelatinosa rolandi and the subjacent dorsal horn in the rat. Science 202:984-986.
14. Giesler GJ, Katter JT, Dado RJ (1994): Direct spinal pathways to the limbic system for nociceptive information. Trends Neurosci 17:244-250.
15. Hunt SP, Pini A, Evan G (1987): Induction of c-fos like protein in spinal cord neurons following sensory stimulation. Nature 328: 632-634.
16. Kawatani M, DeGroat WC (1991): A large proportion of afferent neurons innervating the uterine cervix of the cat contain VIP and other neuropeptides. Cell Tissue Res 266:191-196.
17. Kawatani M, Takeshige M, DeGroat WC (1990): Central distribution of afferent pathways from the uterus of the cat. J Comp Neurol 320:294-304.
18. Komisaruk BR, Larsson K (1971): Suppression of a spinal and a cranial nerve reflex by vaginal or rectal probing in rats. Brain Res 35:231-235.
19. Komisaruk BR, Adler NT, Hutchison J (1972): Genital sensory field: enlargement by estrogen treatment in female rats. Science 178: 1295-1298.
20. Row L-M, Pfaff DW (1973/1974): Effects of estrogen treatment on the size of receptive field and response threshold of pudendal nerve in the female rat. Neuroendocrinology 13:299-313.
21. Kow L-M, Pfaff DW (1975): Dorsal root recording relevant for mating in female rats: identification of receptive fields and effects of peripheral denervation. J Neurobiol 6:23-37.
22. Kow L-M, Zemlan FP, Pfaff DW (1980): Responses of Iumbosacral spinal units to mechanical stimuli related to analysis of lordosis reflex in female rats. J Neurophysiol 43:27-37.
23. Lakoski JM (1989): Introduction: cellular and molecular mechanisms mediating the central regulation of reproductive function through the lifespan. In McEwen BS (ed): "Neural Control of Reproductive Function." New York: Alan R. Liss, Inc., pp 5-31.
24. Langub MC, Maley BE, Watson RE (1993): Estrous cycle-associated axosomatic synaptic plasticity upon estrogen receptive neurons in the rat preoptic area. Brain Res 641:303-310.
25. Legan SJ, Coon GA, Karsch FJ (1975): Role of estrogen as initiator of daily LH surges in the ovariectomized rat. Endocrinology 96: 50-56.
26. Lehman MN, Ebling FJ, Moenter SM, Karsch FJ (1993): Distribution of estrogen receptor immunoreactive cells in the sheep brain. Endocrinology 133:876-86.
27. Li H-Y, Blaustein JD, De Vries GJ, Wade GN (1993): Estrogen- receptor immunoreactivity in hamster brain, preoptic area, hypothalamus and amygdala. Brain Res 631:304-312.
28. McEwen BS (1992): Steroid hormones: effect on brain development and function. Horm Res 37(suppl 3): 1-10.
29. McEwen BS, Coirini H, Westlind-Danielsson A, Frankfurt M, Gould E, Schumacher M, Woolley C (1991): Steroid hormones as mediators of neural plasticity. J Steroid Biochem Molec Biol 39:223-232.
30. McKenna KE, Nadelhaft I (1986): The organization of the pudendal nerve in the male and female rat. J Comp Neurol 248:532-549.
31. Menetrey D, Gannon A, Levine JD, Basbaum A (1989): Expression of c-fos protein in interneurons and projection neurons of the rat spinal cord in response to noxious somatic, articular and visceral stimulation. J Comp Neurol 285:177-195.
32. Morrell JI, Wolinsky TD, Krieger MS, Pfaff DW (1982): Autoradiographic identification of estradiol-concentrating cells in the spinal cord of the female rat. Exp Brain Res 45:144-150.
33. Oblinger MM, Pickett J, Teleghany N, DonCarlos L (1994): Expression and regulation of estrogen receptor (ER) and its mRNA in a subpopulation of rat dorsal root ganglion neurons. Soc Neurosci Abst 20:1693.
34. Okamura H, Yokosuka M, Hayashi S (1994a): Estrogenic induction of NADPH-diaphorase activity in the preoptic neurons containing estrogen receptor immunoreactivity in the female rat. J Neuroendocrinol 6:597-601.
35. Okamura H, Yokosuka M, McEwen BS, Hayashi S (1994b): Colocalization of NADPH diaphorase and estrogen receptor immunoreactivity in the rat ventromedial hypothalamic nucleus: stimulatory effect of estrogen on NADPH-diaphorase activity. Endocrinology 4:1705-1708.
36. Papka RE, McCurdy JR, Williams SJ, Mayer B, Marson L, Platt KB (1995a): Parasympathetic preganglionic neurons in the spinal cord involved in uterine innervation are cholinergic and nitric oxide-containing. Anat Rec 241:544-562.
37. Papka RE, McNeill DL, Thompson D, Schmidt HHHW (1995b): Nitric oxide nerves in the uterus are parasympathetic, sensory and contain neuropeptides. Cell Tiss Res 279:339-349.
38. Pelletier G, Liao N, Follea N, Govindan NV (1988): Mapping of estrogen receptor-producing cells in the rat brain by in situ hybridization. Neurosci Lett 94:23-28.
39. Peters LC, Kristal MB, Komisaruk BR (1987): Sensory innervation of the external and internal genitalia of the female rat. Brain Res 408:199-204.
40. Pfaff DW, Keiner M (1973): Atlas of estradiol-concentrating cells in the CNS of the female rat. J Comp Neurol 151:121-158.
41. Pfaff DW, Schwartz-Giblin S, McCarthy MM, Kow L-M (1994): Cellular and molecular mechanisms of female reproductive behaviors. In E Knobil, J McNeill (eds): "The Physiology of Reproduction." New York: Raven Press, pp 107-220.
42. Robbins A, Sato Y, Hotta H, Berkley KJ (1990): Responses of hypogastric nerve afferent fibers to uterine distension in estrous or metestrous rats. Neurosci Lett 110:82-85.
43. Schrøder HD (1983): Localization of cholecystokinin-like immunoreactivity in the rat spinal cord, with particular reference to the autonomic innervation of the pelvic organs. J Comp Neurol 217:176-186.
44. Schrøder HD (1984): Somatostatin in the caudal spinal cord: an immunohistochemical study of the spinal centers involved in the innervation of pelvic organs. J Comp Neurol 233:400-414.
45. Simerly RB, Chang C, Muramatsu M, Swanson LW (1990): Distribution of androgen and estrogen receptor mRNA-containing cells in the rat brain - an in situ hybridization study. J Comp Neurol 294:76-95.
46. Sohrabji F, Miranda RC, Toran-Allerand CD (1994): Estrogen differ- entially regulates estrogen and nerve growth factor receptor mRNAs in adult sensory neurons. J Neurosci 14:459-471.
47. Srinivasan B, Papka RE, Miller KE (1995): Expression of estrogen receptor (ER) in neurons of rat spinal cord, dorsal root ganglia (DRG) and pelvic autonomie ganglia (PG). Soc Neurosci Abst 21:1874.
48. Stumpf WE, Sar M, Reefer DA (1975): Atlas of estrogen target cells in rat brain. Anatomical Neuroendocrinology For: International Conference of Neurobiology of CNS-Hormone Interactions, Chapel Hill, NC, 1974. Basel, Switzerland: Karger, pp 104-109.
49. Tetel MJ, Celentano DC, Blaustein JD (1994): Intraneuronal convergence of tactile and hormonal stimuli associated with female reproduction in rats. J Neuroendocrinol 6:211-216.
50. Willis WD, Leonard RB, Kenshalo DR (I978): Spinothalamic tract neurons in the substantia gelatinosa. Science 202:986-988.