Essential yeast protein with unexpected similarity to subunits of mammalian cleavage and polyadenylation specificity factor (CPSF)

Science

Volumn 274, Issue 5292, 1996, Pages 1511-1514

  Chanfreau, Guillaume ^a   Noble, Suzanne M ^a   Guthrie, Christine ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR; FUNGAL PROTEIN; MESSENGER RNA; POLYADENYLATED RNA; POLYNUCLEOTIDE ADENYLYLTRANSFERASE; PROTEIN SUBUNIT; TRANS ACTING FACTOR;

AMINO ACID SEQUENCE; ARTICLE; GENE DISRUPTION; GENE ISOLATION; IMMUNOPRECIPITATION; NONHUMAN; NORTHERN BLOTTING; POLYADENYLATION; PRIORITY JOURNAL; RNA CLEAVAGE; RNA PROCESSING; RNA SPLICING; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY; YEAST;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CATTLE; CONSERVED SEQUENCE; CRYSTALLOGRAPHY, X-RAY; FUNGAL PROTEINS; MOLECULAR SEQUENCE DATA; MRNA CLEAVAGE AND POLYADENYLATION FACTORS; MUTATION; POLY A; RNA PRECURSORS; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, FUNGAL; RNA, MESSENGER; RNA-BINDING PROTEINS; SACCHAROMYCES CEREVISIAE;

EUKARYOTA; MAMMALIA; SACCHAROMYCES CEREVISIAE;

EID: 0029807124     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.274.5292.1511     Document Type: Article

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37. We thank W. Keller and F. Lacroute for antibodies and P. Preker for plasmids and helpful advice; A. Gamarnik and R. Andino for help with FPLC; A. Jenny, L. Minvielle-Sebastia, P. Preker, and W. Keller for communication of unpublished results; L. Esperas, C. Pudlow, and H. Roiha for technical assistance; A. Frankel, E. O'Shea, C. Siebel, and J. Staley for critical reading of the manuscript; H. Madhani for noting the Synechocystis bfh sequence and major help with the manuscript; and members of the Guthrie laboratory for sharing experimental expertise. Supported by NIH grant GM21119 (C.G.), a Human Frontier Science Program long-term postdoctoral fellowship (G.C.), and an American Heart Association Predoctoral Fellowship (S.N.). C.G. is an American Cancer Society Research Professor of Molecular Genetics.