Peripheral blood mononuclear cells from autologous hematopoietic stem cell transplantation recipients produce and respond to 1L-12

Bone Marrow Transplantation

Volumn 18, Issue 4, 1996, Pages 733-739

  Guillaume, T ^a   Kubin, M ^b   Sekhavat, M ^a   Rubinstein, D B ^c   Trinchieri, G ^d   Symann, M ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b AMGEN INC   (United States)

^c BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d WISTAR INSTITUTE   (United States)

Author keywords

Autologous stem cell transplantation; IL 12

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 2; STAPHYLOCOCCUS TOXIN; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL CULTURE; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; HELPER CELL; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; MONONUCLEAR CELL; NATURAL KILLER CELL; PRIORITY JOURNAL; STEM CELL TRANSPLANTATION; T LYMPHOCYTE SUBPOPULATION;

CASE-CONTROL STUDIES; CD4-POSITIVE T-LYMPHOCYTES; FEMALE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; INTERLEUKIN-12; INTERLEUKIN-2; LEUKOCYTES, MONONUCLEAR; LYMPHOCYTE ACTIVATION; MITOGENS; STAPHYLOCOCCUS AUREUS; TRANSPLANTATION, AUTOLOGOUS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0029807120     PISSN: 02683369     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Antman KH, Souhami RL. High-dose chemotherapy in solid tumors. A review of published data in selected tumors with a commentary. Ann Oncol 1993; 4 (Suppl. 1): 29-44.
2. Coiffier B, Philip T, Burnett AK, Symann ML. Consensus conference on intensive chemotherapy plus hematopoietic stem-cell transplantation in malignancies: Lyon, France, June 4-6, 1993. J Clin Oncol 1994; 12: 226-231.
3. Witherspoon RP. Immunologic reconstitution after high-dose chemoradiotherapy and allogeneic or autologous bone marrow or peripheral blood hematopoietic stem cell transplantation. In: Armitage JO, Antman KH (eds). High-Dose Cancer Therapy: Pharmacology, Hematopoietins, Stem Cells. Williams and Wilkins: Baltimore, 1995, pp 242-258.
4. Singer CRJ, Tansey PJ, Burnett AK. T lymphocyte reconstitution following autologous bone marrow transplantation. Clin Exp Immunol 1983; 51: 455-460.
5. Linch DC, Knott LJ, Thomas RM et al. T cell regeneration after allogeneic and autologous bone marrow transplantation. Br J Haematol 1983; 53: 451-458.
6. Ueda M, Harada M, Shiobara S et al. T lymphocyte reconstitution in long-term survivors after allogeneic and autologous marrow transplantation. Transplantation 1984; 37: 552-556.
7. Welte K, Ciobanu N, Moore MAS et al. Defective interleukin 2 production in patients after bone marrow transplantation and in vitro restoration of defective T lymphocyte proliferation by highly purified interleukin 2. Blood 1984; 64: 380-385.
8. Bosly A, Staquet P, Doyen C et al. Recombinant human interleukin-2 restores in vitro T-cell colony formation by peripheral blood mononuclear cells after autologous bone marrow transplantation. Exp Hematol 1987; 15: 1048-1054.
9. + cells even in the presence of exogenous IL-2. Blood 1989; 74: 2270-2277.
10. Miller RA, Daley J, Ghalie R, Kaizer H. Clonal analysis of T-cell deficiencies in autotransplant recipients. Blood 1991; 77: 1845-1850.
11. Guillaume T, Sekhavat M, Rubinstein DB et al. Defective cytokine production following autologous stem cell transplantation for solid tumors and hematologic malignancies regardless of bone marrow or peripheral origin and lack of evidence for a role for interleukin-10 in delayed immune reconstitution. Cancer Res 1994; 54: 3800-3807.
12. Olsen GA, Gockerman JP, Bast RC et al. Altered immunologic reconstitution after standard-dose chemotherapy or high-dose chemotherapy with autologous bone marrow support. Transplantation 1988; 46: 57-60.
13. Bengtsson M, Tötterman TH, Smedmyr B et al. Regeneration of functional and activated NK and T sub-subset cells in the marrow and blood after autologous bone marrow transplantation: a prospective phenotypic study with 2/3-color FACS analysis. Leukemia 1989; 3: 68-75.
14. Sugita K, Soiffer RJ, Murray C et al. The phenotype and reconstitution of immunoregulatory T cell subsets after T cell-depleted allogeneic and autologous bone marrow transplantation. Transplantation 1994; 57: 1465-1473.
15. Sugita K, Nojima Y, Tachibana K et al. Prolonged impairment of very late activating antigen-mediated T cell proliferation via the CD3 pathway after T cell-depleted allogeneic bone marrow transplantation. J Clin Invest 1994; 94: 481-488.
16. Storek J, Witherspoon RP, Storb R. T cell reconstitution after bone marrow transplantation into adult patients does not resemble T cell development in early life. Bone Marrow Transplant 1995; 16: 413-425.
17. Yamagami M, McFadden PW, Koethe SM et al. Failure of T cell receptor anti-CD3 monoclonal antibody interaction in T cells from bone marrow recipients to induce increases in intracellular ionized calcium. J Clin Invest 1990; 86: 1347-1351.
18. + T cells in response to mitogen following autologous bone marrow transplantation. Br J Haematol 1993; 84: 131-136.
19. Jin N-R, Lum LG, Buren EV et al. Signal transduction by B and T cells early after bone marrow transplantation: B cell calcium flux responses are intact whereas lack of CD4 cells accounts for impaired T cell responses. Bone Marrow Transplant 1995; 16: 103-109.
20. Trinchieri G. Interleukin-12: a cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T-helper type I and cytotoxic lymphocytes. Blood 1994; 84: 4008-4027.
21. D'Andrea A, Rengaraju M, Valiante NM et al. Production of natural killer cell stimulatory factor (NKSF/IL-12) by peripheral blood mononuclear cells. J Exp Med 1992; 176: 1387-1398.
22. + T cells. J Immunol 1995; 154: 5071-5079.
23. Cassatella MA, Meda L, D'Andrea A et al. Interleukin-12 production by human polymorphonuclear leukocytes. Eur J Immunol 1995; 25: 1-5.
24. Kobayashi M, Fitz L, Ryan M et al. Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biological effects on human lymphocytes. J Exp Med 1989; 170: 827-845.
25. Chehimi J, Starr S, Frank I et al. Natural killer cell stimulatory factor (NKSF) increases the cytotoxic activity of NK cells from both healthy donors and HIV-infected patients. J Exp Med 1992; 175: 789-796.
26. Gately MK, Wolitzky AG, Quinn PM, Chizzonite R. Regulation of human cytolytic lymphocyte responses by interleukin-12. Cell Immunol 1992; 143: 127-142.
27. Chan SH, Kobayashi M, Santoli D et al. Mechanisms of IFN-γ induction by natural killer cells stimulatory factor (NKSF/IL-12): role of transcription and mRNA stability in the synergistic interaction between NKSF and IL-2. J Immunol 1992; 148: 92-98.
28. Brunda MJ, Luistro L, Warriei RR et al. Antitumor and antimetastatic activity of interleukin 12 against murine tumors. J Exp Med 1993; 178: 1223-1230.
29. Nastala CL, Edington HD, McKinney TG et al. Recombinant IL-12 administration induces tumor regression in association with IFN-γ production. J Immunol 1994; 153: 1697-1706.
30. Soiffer RJ, Robertson MJ, Murray C et al. Interleukin-12 augments cytolytic activity of peripheral blood lymphocytes from patients with hematologic and solid malignancies. Blood 1993; 82: 2790-2796.
31. Kubin M, Chow JM, Trinchieri G. Differential regulation of interleukin-12 (IL-12), tumor necrosis factor α, and IL-1β production in human myeloid cell lines and peripheral blood mononuclear cells. Blood 1994; 83: 1847-1855.
32. Gately MK, Desai B, Wolitzky AG et al. Regulation of human lymphocyte proliferation by a heterodimeric cytokine. IL-12 (cytotoxic lymphocyte maturation factor). J Immunol 1991; 147: 874-882.
33. + T lymphocytes, and NK cells. J Immunol 1992; 149: 3495-3502.
34. Bertagnolli MM, Lin BY, Young D, Herrmann SH. IL-12 augments antigen-dependent proliferation of activated T lymphocytes. J Immunol 1992; 149: 3778-3783.
35. Desai BB, Quinn PM, Wolitzky AG et al. The IL-12 receptor. II. Distribution and regulation of receptor expression. J Immunol 1992; 148: 3125-3132.
36. Kubin M, Kamoun M, Trinchieri G. Interleukin 12 synergizes with B7/CD28 interaction in inducing efficient proliferation and cytokine production of human T cells. J Exp Med 1994; 180: 211-222.
37. + NK cells. J Immunol 1992; 148: 2429-2436.
38. Reittie JE, Gottlieb D, Heslop HE et al. Endogenously generated activated killer cells circulate after autologous and allogeneic marrow transplantation but not after chemotherapy. Blood 1989; 73: 1351-1358.
39. Roberts MM, To LB, Gillis D et al. Immune reconstitution following peripheral blood stem cell transplantation, autologous bone marrow transplantation and allogeneic bone marrow transplantation. Bone Marrow Transplant 1993; 12: 469-475.
40. Scambia G, Panici PB, Pierelli L et al. Immunological reconstitution after high-dose chemotherapy and autologous blood stem cell transplantation for advanced ovarian cancer. Eur J Cancer 1993; 29A: 1518-1522.
41. Zeh HJ III, Hurd S, Storkus WJ, Lotze MT. Interleukin-12 promotes the proliferation and cytolytic maturation of immune effectors: implications for the immunotherapy of cancer. J Immunother 1993; 14: 155-161.
42. O'Toole M, Wolf SF, O'Brien C et al. Effect of in vivo IL-12 administration on murine tumor cell growth. J Immunol 1993; 150: 294A.
43. Kanangat S, Nair S, Babu JS, Rouse BT. Expression of cytokine mRNA in murine splenic dendritic cell and better induction of T cell-derived cytokines by dendritic cells than by macrophages during in vitro costimulation assay using specific antigens. J Leuk Biol 1995; 57: 310-316.
44. + T cells. J Immunol 1995; 154: 5071-5079.