Randomized trial radiotherapy with and without concomitant 13-cis-retinoic acid plus interferon-alpha for locally advanced cervical cancer : A preliminary report

Journal of the Medical Association of Thailand

Volumn 79, Issue 7, 1996, Pages

  Veerasarn, Vutisiri ^a   Sritongchai, Chaisit ^b   Tepmongkol, Pairat ^a   Senapad, Sumrit ^a  

^a MAHIDOL UNIVERSITY   (Thailand)

^b CHONBURI HOSPITAL   (Thailand)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; ISOTRETINOIN;

ADULT; ADVANCED CANCER; AGED; ARTICLE; CANCER SURVIVAL; CHEILITIS; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; DRY SKIN; FEMALE; FEVER; HUMAN; RANDOMIZED CONTROLLED TRIAL; SUBCUTANEOUS DRUG ADMINISTRATION; UTERINE CERVIX CANCER;

ADULT; AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CASE-CONTROL STUDIES; CHEMOTHERAPY, ADJUVANT; FEMALE; FOLLOW-UP STUDIES; HUMANS; INTERFERON-ALPHA; LONGITUDINAL STUDIES; MIDDLE AGED; TREATMENT OUTCOME; TRETINOIN; UTERINE CERVICAL NEOPLASMS;

EID: 0029806999     PISSN: 01252208     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Perez CA. Result of therapy, Uterine cervix. In : Perez CA, Brady LW, eds. Principles and practice of radiation oncology, 2 nd ed. Philadelphia : J.B. Lippincott company, 1992; pp. 1167-82.
2. Fowler J, Montz FJ. Malignancies of the uterine cervix. In : Cameron RB, ed. Practical oncology. Connecticut : Appleton & Lange, 1994; pp. 364-76.
3. Montana GS, Martz KL, Hanks GE. Patterns and sites of failure in cervix cancer treated in the U.S.A. in 1978. Int J Radiat Oncol Biol Phys 1991; 20: 87-93.
4. Fagundes H, Perez CA, Grigsby PW, Lockett MA. Distant metastases after irradiation alone in carcinoma of the uterine cervix. Int J Radiat Oncol Biol Phys 1992; 24: 197-204.
5. Lowrey GC, Mendenhall WM, Million RR. Stage I B or II A-B carcinoma of the intact uterine cervix treated with irradiation : A multivariated analysis. Int J Radiat Oncol Biol Phys 1992; 24: 205-10.
6. Lanciano RM, Pajak TF, Martz K, Hanks GE. The influence of treatment time on outcome for squamous cell cancer of the uterine cervix treated with radiation : A pattern-of-care study. Int J Radiat Oncol Biol Phys 1993; 25: 391-7.
7. Sardi J, Sananes C, Giaroli A, Maya G, di Paola G. Neoadjuvant chemotherapy in locally advanced carcinoma of the cervix uteri. Gynecol Oncol 1990; 38: 486-93.
8. Park TK, Choi DH, Kim SN, et al. Role of induction chemotherapy in invasive cervical cancer. Gynecol Oncol 1991; 41: 107-22.
9. Khoury GG, Bulman AS, Joslin CAF, Rothwell RT. Concomitant pelvic irradiation, 5-fluorouracil and mitomycin-c in the treatment advanced cervical carcinoma. Brit J Radiol 1991; 64: 252-60.
10. Panici PB, Scambia G, Baiocchi G, et al. Neoadjuvant chemotherapy and radical surgery in locally advanced cervical cancer. Cancer 1991; 67: 372-9.
11. Lippman SM, Kavanagh JJ, Paredes-Espinoza M, et al. 13-cis-Retinoic acid plus Interferon-alpha 2a : High active systemic therapy for squamous cell carcinoma of the cervix. J Nat Cancer Inst 1992; 84: 241-5.
12. Lippman SM, Kavanagh JJ, Paredes-Espinoza M, et al. 13-cis-Retinoic acid plus Interferon-alpha 2a in locally advanced squamous cell carcinoma of the cervix. J Nat Cancer Inst 1993; 85: 499-500.
13. Lippman SM, Parkinson DR, Itri LM, et al. 13-cis-Retinoic acid and Interferon-alpha 2a : Effective combination therapy for advanced squamous cell carcinoma of the skin. J Nat cancer Inst 1992; 84: 235-40.
14. Wadler S. The role of Interferons in the treatment of solid tumors. Cancer supplement 1992; 70: 949-58.
15. Wadler S, Schwartz EL. Biologic agents as biochemical modulators : pharmacologic basis for the interaction of cytotoxic chemotherapeutic drugs and Interferon. Cancer Chemther Pharmacol 1994; 35: 21-30.
16. Vokes EE. The promise of biochemical modulation in combined modality therapy. Seminars in Oncology 1994; 21: 29-33.
17. Chadha KC, Ambrus JL, Halpern J, et al. The Interferon system in carcinoma of the cervix. Cancer 1991; 67: 87-90.
18. Sporn MB, Roberts AB. Role of Retinoids in differentiation and carcinogenesis. Cancer Research 1983; 43: 3034-40.
19. Marson KA, Tofilon PJ. Unexpected radiation-protection with 13-cis-retinoic acid plus interferon alpha-2a. Cancer Chemother Pharmacol 1994; 33: 435-7.
20. Angioli R, Sevin BU, Perras JP, et al. In vitro potentiation of radiation cytotoxicity by recombinant interferons in cervical cancer cell lines. Cancer 1993; 71: 3717-25.
21. Angioli R, Sevin BU, Perras JP, et al. Rationale of combining radiation and Interferon for the treatment of cervical cancer. Oncology 1992; 49: 445-9.
22. Hansen RM, Borden EC. Current status of interferon in the treatment of cancer. Oncology 1992; 6: 19-24.