Glutathione modulates the formation of 8-hydroxydeoxy guanosine in isolated DNA and mutagenicity in Salmonella typhimurium TA100 induced by mineral fibres

Carcinogenesis

Volumn 17, Issue 10, 1996, Pages 2275-2277

  Howden, Peter J ^a   Faux, Stephen P ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ACETYLCYSTEINE; BUTHIONINE SULFOXIMINE; CHRYSOTILE; CROCIDOLITE; GLUTATHIONE; IRON; MINERAL FIBER; MUTAGENIC AGENT; OXYGEN RADICAL; SCAVENGER;

ARTICLE; BACTERIUM CULTURE; CONTROLLED STUDY; DNA MODIFICATION; MUTAGENICITY; NONHUMAN; PRIORITY JOURNAL; REVERTANT; SALMONELLA TYPHIMURIUM;

ASBESTOS, CROCIDOLITE; DEOXYGUANOSINE; DNA ADDUCTS; DNA, BACTERIAL; GLUTATHIONE; MINERAL FIBERS; MUTAGENICITY TESTS; MUTAGENS; OXIDATION-REDUCTION; SALMONELLA TYPHIMURIUM;

EID: 0029806353     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/17.10.2275     Document Type: Article

References (29)

1. Wagner, J.C., Berry, G. and Timbrell, V. (1971) Epidemiology of asbestos cancers. Br. Med. Bull., 27, 71-76.
2. Craighead, J.E. and Mossman, B.T. (1982) The pathogenesis of asbestos-associated diseases. N. Engl. J. Med., 306, 1446-1455.
3. Wagner, J.C., Berry, G. and Timbrell, V. (1973) Mesothelioma in rats after inoculation with asbestos and other materials. Br. J. Cancer, 28, 173-185.
4. Stanton, M.F. and Wrench, C. (1972) Mechanism of mesothelioma induction with asbestos and fibrous glass. J. Natl Cancer Inst., 48, 797-821.
5. Donaldson, K., Brown, R.C. and Brown, G.M. (1993) Respirable industrial fibres: mechanisms of pathogenicity. Thorax, 48, 390-395.
6. Turver, C.J. and Brown, R.C. (1987) The role of catalytic iron in asbestos induced lipid peroxidation and DNA-strand breakage in C3H10T1/2 cells. Br. J. Cancer. 56, 133-136.
7. Lund, L.G. and Aust, A.E. (1992) Iron mobilisation from crocidolite asbestos greatly enhances crocidolite-dependent formation of DNA single strand breaks in ΦX174 RFI DNA. Carcinogenesis, 13, 637-642.
8. Weitzman, S.A. and Weitberg, A.B. (1985) Asbestos-catalysed lipid peroxidation and its inhibition by desferrioxamine. Biochem. J., 225, 259-262.
9. Leanderson, P., Soderkvist, P., Tagesson, C. and Axelson, O. (1988) Formation of 8-hydroxydeoxyguanosine by asbestos and man-made mineral fibres. Br. J. Ind. Med., 45, 309-311.
10. Faux, S.P., Howden, P.J. and Levy, L.S. (1994) Iron-dependent formation of 8-hydroxydeoxyguanosine in isolated DNA and mutagenicity in Salmonella typhimurium TA102 induced by crocidolite. Carcinogenesis, 15, 1749-1751.
11. Lund, L.G. and Aust, A.E. (1991) Iron-catalysed reactions may be responsible for the biochemical and biological effects of asbestos. Biofactors, 3, 83-89.
12. Mossman, B.T. and Marsh, J.P. (1989) Evidence supporting a role for active oxygen species in asbestos-induced toxicity and lung disease. Environ. Health Perspect., 81, 91-94.
13. Boveris, A., Oshino, N. and Chance, B. (1972) The cellular production of hydrogen peroxide. Biochem. J., 128, 617-630.
14. Weitzman, S.A. and Graceffa, P. (1984) Asbestos catalyses hydroxyl and Superoxide radical generation from hydrogen peroxide. Arch. Biochem. Biophys., 228, 373-376.
15. Mahmood, N., Khan, S.G., Athar, M. and Rahman, Q. (1994) Differential role of hydrogen peroxide and organic peroxides in augmenting asbestos-mediated DNA damage: Implications for asbestos induced carcinogenesis. Biochem. Biophys. Res. Commun., 200, 687-694.
16. Chance, B., Sies, H. and Boveris, A. (1979) Hydroperoxide metabolism in mammalian organs. Physiol. Rev., 59, 527-605.
17. Faux, S.P., Francis, J.E., Smith, A.G. and Chipman, J.K. (1992) Induction of 8-hydroxydeoxyguanosine in Ah-responsive mouse liver by iron and Aroclor 1254. Carcinogenesis, 13, 247-250.
18. Floyd, R.A., Watson, J.J., Wong, P.K., Atmiller, D.H. and Rickard, R.C. (1986) Hydroxyl free radical adduct of deoxyguanosine: sensitive detection and mechanisms of formation. Free Radical Res. Commun., 1, 163-172.
19. Bouter, S., Kerklaan, P.R.M., Zoetemelk, C.E.M. and Mohn, G.R. (1988) Biochemical characterization of glutathione-deficient mutants of Escherichia coli K12 and Salmonella strains TA1535 and TA100. Biochem. Pharmacol., 37, 577-581.
20. Maron, D.M. and Ames, B.N. (1983) Revised methods for the Salmonella mutagenicity assay. Mutat. Res., 113, 173-215.
21. Yahagi, T., Degawa, M., Seino, T. Matsushima, M., Nagao, M., Sugimura, T. and Hashimoto, Y. (1975) Mutagenicity of carcinogenic azo dyes and their derivatives. Cancer Lett., 1, 91-96.
22. Griffith, O.W. and Meister, A. (1979) Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine). J. Biol. Chem., 254, 7558-7560.
23. Reed, D.J. and Orrenius, S. (1977) The role of methionine in glutathione biosynthesis by isolated hepatocytes. Biochem. Biophys. Res. Commun., 77, 1257-1264.
24. Hissin, P.J. and Hilf, R. (1976) A fluorometric method for the determination of oxidised and reduced glutathione in tissues. Anal. Biochem., 74, 214-226.
25. 2+-sequestration by the plasma membrane fraction from rat liver. FEBS Lett., 163, 136-139.
26. Murphy, M.E., Scholich, H. and Sies, H. (1992) Protection by glutathione and other thiol compounds against the loss of protein thiols and tocopherol homologs during microsomal lipid peroxidation. Eur. J. Biochem., 210, 139-146.
27. Howden, P.J. and Faux, S.P. (1996) Fibre-induced lipid peroxidation leads to DNA adduct formation in Salmonella typhimurium TA104 and rat lung fibroblasts. Carcinogenesis, 17, 413-419.
28. Janssen, Y.M.W., Heintz, N.H. and Mossman, B.T. (1995) Induction of c-fos and c-jun proto-oncogene expression by asbestos is ameliorated by N-acetyl-L-cysteine in mesothelial cells. Cancer Res., 55, 2085-2089.
29. Meister, A. (1994) Glutathione, ascorbate, and cellular protection. Cancer Res., 54 (Suppl.), 1969-1975.