Release of sulfur mustard-modified DNA bases by Escherichia coli 3-methyladenine DNA glycosylase II

Carcinogenesis

Volumn 17, Issue 10, 1996, Pages 2249-2252

  Matijasevic, Zdenka ^a   Stering, Allen ^a   Niu, Tian Qi ^a   Austin Ritchie, Paula ^a   Ludlum, David B ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 METHYLADENINE; ADENINE DERIVATIVE; CARBON 14; DNA GLYCOSYLTRANSFERASE; GUANINE DERIVATIVE; HYDROXYL GROUP; MUSTARD GAS;

ARTICLE; CATTLE; CELL PROTECTION; CONTROLLED STUDY; CROSS LINKING; DNA ADDUCT; DNA MODIFICATION; ENZYME SUBSTRATE; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL; THYMUS; TOXICITY;

DNA ADDUCTS; DNA GLYCOSYLASES; DNA REPAIR; ESCHERICHIA COLI; MUSTARD GAS; N-GLYCOSYL HYDROLASES; SUBSTRATE SPECIFICITY;

EID: 0029806050     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/17.10.2249     Document Type: Article

References (23)

1. IARC (1987) IARC Monographs on the Evaluation of Carcinogenic Risks to Humans: Overall Evaluations of Carcinogenicity. An updating of IARC Monographs Volumes 1 to 42. Suppl. 7, IARC, Lyon, pp 259-260.
2. Papirmeister, B., Feister, A.J., Robinson, S.I. and Ford, R.D. (1991) Medical Defense Against Mustard Gas: Toxic Mechanisms and Pharmacological Implications. CRC Press, Boca Raton, FL, p. 102.
3. Lawley, P.D., Lethbridge, J.H., Edwards, P.A. and Shooter, K.V. (1969) Inactivation of bacteriophage T7 by mono- and difunctional sulfur mustards in relation to cross-linking and depurination of bacteriophage DNA. J. Mol. Biol., 39, 181-198.
4. Fidder, A., Moes, G.W.H., Scheffer, A.G., van der Schans, G.P, Baan, R.A., de Jong, L.P.A. and Benschop, H.P. (1994) Synthesis, characterization and quantitation of the major adducts formed between sulfur mustard and DNA of calf thymus and human blood. Chem. Res. Toxicol., 7, 199-204.
5. Ludlum, D.B., Austin-Ritchie, P., Hagopian, M., Niu, T.-Q. and Yu, D. (1994) Detection of sulfur mustard-induced DNA modifications. Chem.-Biol. Interactions, 91, 39-49.
6. 6-alkylguanine-DNA alkyltransferase. Carcinogenesis, 7, 1203-1206.
7. Papirmeister, B. and Davison, C.L. (1964) Elimination of sulfur mustard-induced products from DNA of Escherichia coli. Biochem. Biophys. Res. Commun., 17, 608-617.
8. Lawley, P.D. and Brookes, P. (1965) Molecular mechanism of the cytotoxic action of difunctional alkylating agents and of resistance to this action. Nature, 206, 480-483.
9. S-1 and their removal by the resistant strain. Biochem. Biophys. Res. Commun., 31, 355-360.
10. Crathorn, A.R. and Roberts, J.J. (1966) Mechanism of the cytotoxic action of alkylating agents in mammalian cells and evidence for the removal of alkylated groups from deoxynucleic acid. Nature, 211, 150-153.
11. Reid, B.D. and Walker, I.D. (1969) The response of mammalian cells to alkylating agents II. On the mechanism of the removal of sulfur mustard-induced cross-links. Biochim. Biophys. Acta, 179, 179-188.
12. Mol, M.A.E., van der Schans, G.P. and Lohman, P.H.M. (1993) Quantification of sulfur mustard-induced DNA interstrand cross-links and single-strand breaks in cultured human epidermal keratinocytes. Mutat. Res., 294, 235-245.
13. Gilbert, R.M., Rowland, S., Davison, C.L. and Papirmeister, B. (1975) Involvement of separate pathways in the repair of mutational and lethal lesions induced by a monofunctional sulfur mustard. Mutat. Res., 28, 257-275.
14. Habraken, Y. and Ludlum, D.B. (1989) Release of chloroethyl ethyl sulfide-modified DNA bases by bacterial 3-methyladenine-DNA glycosylases I and II. Carcinogenesis, 10, 489-492.
15. Habraken, Y., Carter, C.A., Kirk, M.C. and Ludlum, D.B. (1991) Release of 7-alkylguanines from N-(2-chloroethyl)-N′-cyclohexyl-N′-nitrosourea-modified DNA by 3-methyladenine DNA glycosylase. Cancer Res., 51, 499-503.
16. Tsou, K.C, Su, H.C.F., Segebarth, C. and Mirarchi, U. (1961) Synthesis of possible cancer chemotherapeutic compounds based on enzyme approach. I. Hemisulfur mustard and its esters. J. Org. Chem., 26, 4987-4990.
17. Matijasevic, Z., Bodell, W.J. and Ludlum, D.B. (1991) 3-Methyladenine DNA glycosylase activity in a glial cell line sensitive to the haloethylnitrosoureas in comparison with a resistant cell line. Cancer Res., 51, 1568-1570.
18. Nakabeppu, Y., Kondo, H. and Sekiguchi, M. (1984) Cloning and characterization of alkA gene of Escherichia coli that encodes 3-methyladenine-DNA glycosylase II. J. Biol. Chem., 259, 13723-13729.
19. Thomas, L., Yang, C.-H. and Goldthwait, D.A. (1982) Two DNA glycosylases in Escherichia coli which release primarily 3-methyladenine. Biochemistry, 21, 1162-1169.
20. Ludlum, D.B. (1996) Development of the nitrosoureas. In Teicher, B.A. (ed.), Cancer Drug Discovery. Humana Press, Inc., NJ, in press.
21. Habraken, Y., Carter, C.A., Sekiguchi, M. and Ludlum, D.B. (1991) Release of N2,3-ethanoguanine from haloethylnitrosourea-treated DNA by Escherichia coli 3-methyladenine DNA glycosylase II. Carcinogenesis, 12, 1971-1973.
22. Matijasevic, Z., Sekiguchi, M. and Ludlum, D.B. (1992) Release of N2,3-ethenoguanine from chloroacetaldehyde-treated DNA by E.coli 3-methyladenine DNA glycosylase II. Proc. Natl Acad. Sci. USA, 89, 9331-9334.
23. Dosanjh, M.K., Chenna, A., Kim, E., Fraenkel-Conrat, H., Samson, L. and Singer, B. (1994) All four known cyclic adducts formed in DNA by the vinyl chloride metabolite chloroacetaldehyde are released by a human DNA glycosylase. Proc. Natl Acad. Sci. USA, 91, 1024-1028.