Masking drug treatments in the Cardiac Arrhythmia Pilot Study (CAPS)

Controlled Clinical Trials

Volumn 17, Issue 4, 1996, Pages 294-303

  Haakenson, C ^a   Akiyama, T ^a   Hallstrom, A ^a   Sather, M R ^a  

^a UNIVERSITY OF NEW MEXICO   (United States)

Author keywords

clinical trials; double blind; double masked; placebo; trial design

Indexed keywords

ENCAINIDE; FLECAINIDE; IMIPRAMINE; MORACIZINE; PLACEBO;

ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG FORMULATION; ELECTROCARDIOGRAM; GASTROINTESTINAL DISEASE; HEART ARRHYTHMIA; HUMAN; MAJOR CLINICAL STUDY; METHODOLOGY; MULTICENTER STUDY; RANDOMIZED CONTROLLED TRIAL; STATISTICS; VERTIGO;

EID: 0029806023     PISSN: 01972456     EISSN: None     Source Type: Journal    
DOI: 10.1016/0197-2456(95)00195-6     Document Type: Article

References (6)

1. J Howard AS Whittemore JJ Hoover How blind was the patient blind in MIS? FASHP for the CAPS Investigators Clin Pharmacol Ther 32 1982 543 553
2. RP Byington JD Curb ME Mattson Assessment of double-blindness at the conclusion of the β-blocker heart attack trial JAMA 253 1985 1733 1736
3. M Moscucci L Byrne M Weintraub Masking, unmasking, and the placebo effect: an analysis of patients' guesses of treatment assignment in a double-blind clinical trial Clin Pharmacol Ther 41 1987 259 265
4. PG Ney C Collins C Spensor Double-blind: double talk or are there ways to do better research? Med Hypotheses 21 1986 119 126
5. The CAPS Investigators The cardiac arrhythmia pilot study Am J Cardiol 57 1986 91 95
6. The Cardiac Arrhythmia Pilot Study (CAPS) Investigators Effects of encainide, flecainide, imipramine and moricizine on ventricular arrhythmias during the year after acute myocardial infarction: the CAPS Am J Cardiol 61 1988 501 509