-
1
-
-
0025343230
-
Signal transduction by receptors with tyrosine kinase activity
-
Ullrich A, Schlessinger J. Signal transduction by receptors with tyrosine kinase activity. Cell 1990; 61: 203-212
-
(1990)
Cell
, vol.61
, pp. 203-212
-
-
Ullrich, A.1
Schlessinger, J.2
-
2
-
-
0028170817
-
Receptor proteintyrosine kinases and their signal transduction pathways
-
Van der Geer P, Hunter T, Lindberg RA. Receptor proteintyrosine kinases and their signal transduction pathways. Annu Rev Cell Biol 1994; 10: 251-337
-
(1994)
Annu Rev Cell Biol
, vol.10
, pp. 251-337
-
-
Van Der Geer, P.1
Hunter, T.2
Lindberg, R.A.3
-
3
-
-
0023885305
-
The protein tyrosine kinase family: Conserved features and deduced phytogeny of the catalytic domains
-
Hanks SK, Quinn AM, Hunter T. The protein tyrosine kinase family: conserved features and deduced phytogeny of the catalytic domains. Science 1988; 241: 42-52
-
(1988)
Science
, vol.241
, pp. 42-52
-
-
Hanks, S.K.1
Quinn, A.M.2
Hunter, T.3
-
4
-
-
0026336662
-
Protein kinase classification
-
Hunter T. Protein kinase classification. Meth Enzymol 1991; 200: 3-37
-
(1991)
Meth Enzymol
, vol.200
, pp. 3-37
-
-
Hunter, T.1
-
5
-
-
0021281324
-
Close similarity of epidermal growth factor receptor and v-erbB oncogene protein sequences
-
Downward J, Yarden Y, Mayes E, Scarce G, Totty N, Stockwell P et al. Close similarity of epidermal growth factor receptor and v-erbB oncogene protein sequences. Nature 1984; 307: 521-527
-
(1984)
Nature
, vol.307
, pp. 521-527
-
-
Downward, J.1
Yarden, Y.2
Mayes, E.3
Scarce, G.4
Totty, N.5
Stockwell, P.6
-
6
-
-
0021273420
-
Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells
-
Ullrich A, Coussens L, Hayflick JS, Dull TJ, Gray A, Tam AW et al. Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells. Nature 1984; 309: 418-425
-
(1984)
Nature
, vol.309
, pp. 418-425
-
-
Ullrich, A.1
Coussens, L.2
Hayflick, J.S.3
Dull, T.J.4
Gray, A.5
Tam, A.W.6
-
7
-
-
0021985413
-
Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes
-
Ullrich A, Bell JR, Chen EY, Herrera R, Petruzelli LM, Dull TJ et al. Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes. Nature 1985; 313: 756-761
-
(1985)
Nature
, vol.313
, pp. 756-761
-
-
Ullrich, A.1
Bell, J.R.2
Chen, E.Y.3
Herrera, R.4
Petruzelli, L.M.5
Dull, T.J.6
-
8
-
-
0021924895
-
The human insulin receptor cDNA: The structural basis for hormone-activated transmembrane signaling
-
Ebina Y, Ellis L, Jarnagin K, Edery M, Graf L, Clauser E et al. The human insulin receptor cDNA: the structural basis for hormone-activated transmembrane signaling. Cell 1985; 40: 747-758
-
(1985)
Cell
, vol.40
, pp. 747-758
-
-
Ebina, Y.1
Ellis, L.2
Jarnagin, K.3
Edery, M.4
Graf, L.5
Clauser, E.6
-
9
-
-
0027953703
-
Insulin action, diabetogenes, and the cause of type II diabetes
-
Kahn CR. Insulin action, diabetogenes, and the cause of type II diabetes. Diabetes 1994; 43: 1066-1084
-
(1994)
Diabetes
, vol.43
, pp. 1066-1084
-
-
Kahn, C.R.1
-
10
-
-
0026761432
-
Mutations in the insulin receptor gene
-
Taylor SI, Cama A, Accili D, Barbetti F, Quon MJ, de la Luz Sierra M et al. Mutations in the insulin receptor gene. Endocr Rev 1992; 13: 566-595
-
(1992)
Endocr Rev
, vol.13
, pp. 566-595
-
-
Taylor, S.I.1
Cama, A.2
Accili, D.3
Barbetti, F.4
Quon, M.J.5
De La Luz Sierra, M.6
-
11
-
-
0022800838
-
Insulin-like growth factor-1 receptor primary structure: Comparison with insulin receptor suggests structural determinants that define functional specificity
-
Ullrich A, Gray A, Tam AW, Yang-Fen T, Tsubokawa M, Collins C et al. Insulin-like growth factor-1 receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity. EMBO J 1986; 5: 2503-2512
-
(1986)
EMBO J
, vol.5
, pp. 2503-2512
-
-
Ullrich, A.1
Gray, A.2
Tam, A.W.3
Yang-Fen, T.4
Tsubokawa, M.5
Collins, C.6
-
12
-
-
0028103767
-
Insulin-like growth factor-1: Molecular biology and relevance to tissue specific expression and action
-
Lund PK. Insulin-like growth factor-1: Molecular biology and relevance to tissue specific expression and action. Rec Prog Horm Res 1994; 49: 49-148
-
(1994)
Rec Prog Horm Res
, vol.49
, pp. 49-148
-
-
Lund, P.K.1
-
13
-
-
0027496895
-
Mice carrying null mutations of the genes encoding insulin-like growth factor-1 (IGF-1) and type 1 IGF receptor (IGF-1R)
-
Liu JP, Baker J, Perkins AS, Robertson EJ, Efstratiadis A. Mice carrying null mutations of the genes encoding insulin-like growth factor-1 (IGF-1) and type 1 IGF receptor (IGF-1R). Cell 1993; 75: 59-72
-
(1993)
Cell
, vol.75
, pp. 59-72
-
-
Liu, J.P.1
Baker, J.2
Perkins, A.S.3
Robertson, E.J.4
Efstratiadis, A.5
-
14
-
-
0022541219
-
Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors
-
Yarden Y, Escobedo JA, Kuang WJ, Yang-Feng TL, Daniel TO, Tremble PM et al. Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors. Nature 1986; 323: 226-232
-
(1986)
Nature
, vol.323
, pp. 226-232
-
-
Yarden, Y.1
Escobedo, J.A.2
Kuang, W.J.3
Yang-Feng, T.L.4
Daniel, T.O.5
Tremble, P.M.6
-
15
-
-
0026649742
-
Fibroblast growth factor receptor tyrosine kinases: Molecular analysis and signal transduction
-
Jaye M, Schlessinger J, Dionne CA. Fibroblast growth factor receptor tyrosine kinases: molecular analysis and signal transduction. Biochim Biophys Acta 1992; 1135:185-199
-
(1992)
Biochim Biophys Acta
, vol.1135
, pp. 185-199
-
-
Jaye, M.1
Schlessinger, J.2
Dionne, C.A.3
-
16
-
-
0029021660
-
Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium
-
Fong GH, Rossant J, Gertsenstein M, Breitman ML. Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium. Nature 1995; 376:66-70
-
(1995)
Nature
, vol.376
, pp. 66-70
-
-
Fong, G.H.1
Rossant, J.2
Gertsenstein, M.3
Breitman, M.L.4
-
17
-
-
0029006696
-
Failure of blood island formation and vasculogenesis in Flk-1 deficient mice
-
Shalaby F, Rossant J, Yamaguchi TP, Gertsenstein M, Wu XF, Breitman ML et al. Failure of blood island formation and vasculogenesis in Flk-1 deficient mice. Mature 1995; 376: 62-66
-
(1995)
Mature
, vol.376
, pp. 62-66
-
-
Shalaby, F.1
Rossant, J.2
Yamaguchi, T.P.3
Gertsenstein, M.4
Wu, X.F.5
Breitman, M.L.6
-
18
-
-
0029553670
-
Neurotrophins: Neural antiapoptotic molecules with neurite growth-promoting properties
-
Arumäe U. Neurotrophins: neural antiapoptotic molecules with neurite growth-promoting properties. Biomed Rev 1995; 4: 15-27
-
(1995)
Biomed Rev
, vol.4
, pp. 15-27
-
-
Arumäe, U.1
-
19
-
-
0029001244
-
Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation
-
Sato TN, Tozawa Y, Deutsch U, Wolburg-Buchholz K, Fujiwara Y, Gendron-Maguire M et al. Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation. Nature 1995; 376: 70-74
-
(1995)
Nature
, vol.376
, pp. 70-74
-
-
Sato, T.N.1
Tozawa, Y.2
Deutsch, U.3
Wolburg-Buchholz, K.4
Fujiwara, Y.5
Gendron-Maguire, M.6
-
20
-
-
0028174023
-
Defects in the kidney and enteric nervous system in mice lacking the tyrosine receptor Ret
-
Schuchardt A, D'Agati V, Larsson-Blomberg L, Constantini F, Pachis V. Defects in the kidney and enteric nervous system in mice lacking the tyrosine receptor Ret. Nature 1994; 367: 380-383
-
(1994)
Nature
, vol.367
, pp. 380-383
-
-
Schuchardt, A.1
D'Agati, V.2
Larsson-Blomberg, L.3
Constantini, F.4
Pachis, V.5
-
21
-
-
0028104202
-
Regulation of signal transduction and signal diversity by receptor oligomerization
-
Lemmon MA, Schlessinger J. Regulation of signal transduction and signal diversity by receptor oligomerization. Trends Biochem Sci 1994; 19: 459-463
-
(1994)
Trends Biochem Sci
, vol.19
, pp. 459-463
-
-
Lemmon, M.A.1
Schlessinger, J.2
-
22
-
-
0028838012
-
Dimerization of cell surface receptors in signal transduction
-
Heldin CH. Dimerization of cell surface receptors in signal transduction. Cell 1995; 80: 213-223
-
(1995)
Cell
, vol.80
, pp. 213-223
-
-
Heldin, C.H.1
-
23
-
-
0028825543
-
Regulation of growth factor activation by proteoglycans: What is the role of the low-affinity receptors?
-
Schlessinger J, Lax I, Lemmon M. Regulation of growth factor activation by proteoglycans: What is the role of the low-affinity receptors ? Cell 1995; 83: 357-360
-
(1995)
Cell
, vol.83
, pp. 357-360
-
-
Schlessinger, J.1
Lax, I.2
Lemmon, M.3
-
24
-
-
0029164630
-
Eph receptor tyrosine kinases, axon repulsion, and the development of topographic maps
-
Tessier-Lavigne M. Eph receptor tyrosine kinases, axon repulsion, and the development of topographic maps. Cell 1995; 82: 345-348
-
(1995)
Cell
, vol.82
, pp. 345-348
-
-
Tessier-Lavigne, M.1
-
25
-
-
0000352275
-
Eukaryotic protein kinase
-
Hanks SK. Eukaryotic protein kinase. Curr Biol 1991; 1: 369-383
-
(1991)
Curr Biol
, vol.1
, pp. 369-383
-
-
Hanks, S.K.1
-
26
-
-
0026345394
-
Protein kinase catalytic domain sequence database: Identifcation and classification of family members
-
Hanks SK, Quinn AM. Protein kinase catalytic domain sequence database: identifcation and classification of family members. Meth Enzymol 1991; 200: 38-62
-
(1991)
Meth Enzymol
, vol.200
, pp. 38-62
-
-
Hanks, S.K.1
Quinn, A.M.2
-
27
-
-
0028582185
-
Crystal structure of the tyrosine kinase domain of the human insulin receptor
-
Hubbard SR, Wei L, Ellis L, Hendrickson WA. Crystal structure of the tyrosine kinase domain of the human insulin receptor. Nature 1994; 372: 746-753
-
(1994)
Nature
, vol.372
, pp. 746-753
-
-
Hubbard, S.R.1
Wei, L.2
Ellis, L.3
Hendrickson, W.A.4
-
28
-
-
0026342401
-
Crystal structure of the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase
-
Knighton DR, Zheng J, Ten Eyck LF, Ashford VA, Xuong NH, Taylor SS et al. Crystal structure of the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase. Science 1991; 253: 407-414
-
(1991)
Science
, vol.253
, pp. 407-414
-
-
Knighton, D.R.1
Zheng, J.2
Ten Eyck, L.F.3
Ashford, V.A.4
Xuong, N.H.5
Taylor, S.S.6
-
29
-
-
0026484261
-
SH2 and SH3 domains: From structure to function
-
Pawson T, Gish GD. SH2 and SH3 domains: from structure to function. Cell 1992; 71: 359-362
-
(1992)
Cell
, vol.71
, pp. 359-362
-
-
Pawson, T.1
Gish, G.D.2
-
31
-
-
0028895654
-
Modular binding domains in signal transduction proteins
-
Cohen GB, Ren R, Baltimore D. Modular binding domains in signal transduction proteins. Cell 1995; 80: 237-248
-
(1995)
Cell
, vol.80
, pp. 237-248
-
-
Cohen, G.B.1
Ren, R.2
Baltimore, D.3
-
32
-
-
0029640799
-
A phosphotyrosine interaction domain
-
Bork P, Margolis B. A phosphotyrosine interaction domain. Cell 1995; 80: 693-694
-
(1995)
Cell
, vol.80
, pp. 693-694
-
-
Bork, P.1
Margolis, B.2
-
33
-
-
0027183541
-
The PH domain: A common piece in the structural pathwork of signalling proteins
-
Musacchio A, Gibson T, Rice P, Thompson J, Saraste M. The PH domain: a common piece in the structural pathwork of signalling proteins. Trends Biochem Sci 1993; 18: 343-348
-
(1993)
Trends Biochem Sci
, vol.18
, pp. 343-348
-
-
Musacchio, A.1
Gibson, T.2
Rice, P.3
Thompson, J.4
Saraste, M.5
-
34
-
-
0027998458
-
PH domain: The first anniversary
-
Gibson TJ, Hyvönen M, Musacchio A, Saraste M, Birney E. PH domain: the first anniversary. Trends Biochem Sci 1994; 19: 349-353
-
(1994)
Trends Biochem Sci
, vol.19
, pp. 349-353
-
-
Gibson, T.J.1
Hyvönen, M.2
Musacchio, A.3
Saraste, M.4
Birney, E.5
-
35
-
-
0027288910
-
A putative modula domain present in diverse signaling proteins
-
Mayer BJ, Ren R, Clark KL, Baltimore D. A putative modula domain present in diverse signaling proteins. Cell 1993; 73: 629-630
-
(1993)
Cell
, vol.73
, pp. 629-630
-
-
Mayer, B.J.1
Ren, R.2
Clark, K.L.3
Baltimore, D.4
-
37
-
-
0025765803
-
SH2 and SH3 domains: Elements that control interactions of cytoplasmic signaling proteins
-
Koch CA, Anderson D, Moran MF, Ellis C, Pawson T. SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins. Science 1991; 252: 668-674
-
(1991)
Science
, vol.252
, pp. 668-674
-
-
Koch, C.A.1
Anderson, D.2
Moran, M.F.3
Ellis, C.4
Pawson, T.5
-
38
-
-
0026059615
-
The non-catalytic src homology region 2 segment of abl tyrosine kinase binds to tyrosine phosphorylated cellular proteins with high affinity
-
Mayer BI, Jackson PK, Baltimore D. The non-catalytic src homology region 2 segment of abl tyrosine kinase binds to tyrosine phosphorylated cellular proteins with high affinity. Proc Natl Acad Sci USA 1991; 88:627-631
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 627-631
-
-
Mayer, B.I.1
Jackson, P.K.2
Baltimore, D.3
-
39
-
-
0025681492
-
Binding of SH2 domains of phospholipase C gamma 1, GAP, and Src to activated growth factor receptors
-
Anderson D, Koch CA, Grey L, Ellis C, Moran MF, Pawson T. Binding of SH2 domains of phospholipase C gamma 1, GAP, and Src to activated growth factor receptors. Science 1990; 250: 979-982
-
(1990)
Science
, vol.250
, pp. 979-982
-
-
Anderson, D.1
Koch, C.A.2
Grey, L.3
Ellis, C.4
Moran, M.F.5
Pawson, T.6
-
40
-
-
0026652899
-
Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways
-
Fantl WJ, Escobedo JA, Martin GA, Turck CW, del Rosario M, McCormick F et al. Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways. Cell 1992; 69: 413-423
-
(1992)
Cell
, vol.69
, pp. 413-423
-
-
Fantl, W.J.1
Escobedo, J.A.2
Martin, G.A.3
Turck, C.W.4
Del Rosario, M.5
McCormick, F.6
-
41
-
-
0027141001
-
Structures of SH2 and SH3 domains
-
Kuriyan J, Cowburn D. Structures of SH2 and SH3 domains. Curr Biol 1993; 3:828-837
-
(1993)
Curr Biol
, vol.3
, pp. 828-837
-
-
Kuriyan, J.1
Cowburn, D.2
-
42
-
-
0026698924
-
Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine phosphorylated peptides
-
Waksman G, Kominos D, Robertson SC, Pant N, Baltimore D, Birge RB et al. Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine phosphorylated peptides. Nature 1992; 358: 646-653
-
(1992)
Nature
, vol.358
, pp. 646-653
-
-
Waksman, G.1
Kominos, D.2
Robertson, S.C.3
Pant, N.4
Baltimore, D.5
Birge, R.B.6
-
43
-
-
0027409064
-
Binding of high affinity phosphotyrosyl peptide to the Src SH2 domain: Crystal structures of the complexed and peptide-free forms
-
Waksman G, Shoelson SE, Pant N, Cowburn D, Kuriyan J. Binding of high affinity phosphotyrosyl peptide to the Src SH2 domain: crystal structures of the complexed and peptide-free forms. Cell 1993; 72: 779-790
-
(1993)
Cell
, vol.72
, pp. 779-790
-
-
Waksman, G.1
Shoelson, S.E.2
Pant, N.3
Cowburn, D.4
Kuriyan, J.5
-
44
-
-
0027502504
-
Recognition of a high affinity phosphotyrosyl peptide by the Src homology-2 domain of p561ck
-
Eck MJ, Shoelson SE, Harrison SC. Recognition of a high affinity phosphotyrosyl peptide by the Src homology-2 domain of p561ck. Nature 1993; 362: 87-91
-
(1993)
Nature
, vol.362
, pp. 87-91
-
-
Eck, M.J.1
Shoelson, S.E.2
Harrison, S.C.3
-
45
-
-
0026665009
-
Structure of an SH2 domain of the p85α subunit of phosphatidylinositol-3-OH kinase
-
Booker GW, Breeze AL, Downing AK, Panayotou G, Gout I, Waterfield MD et al. Structure of an SH2 domain of the p85α subunit of phosphatidylinositol-3-OH kinase. Nature 1992; 358: 684-687
-
(1992)
Nature
, vol.358
, pp. 684-687
-
-
Booker, G.W.1
Breeze, A.L.2
Downing, A.K.3
Panayotou, G.4
Gout, I.5
Waterfield, M.D.6
-
46
-
-
0026669472
-
3-Dimensional solution structure of the src homology-2 domain of c-Abl
-
Overduin MD, Rios CB, Mayer BJ, Baltimore D, Cowburn D. 3-Dimensional solution structure of the src homology-2 domain of c-Abl. Cell 1992; 70: 697-704
-
(1992)
Cell
, vol.70
, pp. 697-704
-
-
Overduin, M.D.1
Rios, C.B.2
Mayer, B.J.3
Baltimore, D.4
Cowburn, D.5
-
47
-
-
0027071671
-
Secondary structure of the Src homology 2 domain of c-Abl by heteronuclear NMR spectroscopy in solution
-
Overduin MD, Mayer B, Rios CB, Baltimore D, Cowburn D. Secondary structure of the Src homology 2 domain of c-Abl by heteronuclear NMR spectroscopy in solution. Proc Natl Acad Sci USA 1992; 89: 11673-11677
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 11673-11677
-
-
Overduin, M.D.1
Mayer, B.2
Rios, C.B.3
Baltimore, D.4
Cowburn, D.5
-
48
-
-
0027403027
-
SH2 domains recognize specific phosphopeptide sequences
-
Songyang Z, Shoelson SE, Chaudhuri M, Gish G, Pawson T, Haser W et al. SH2 domains recognize specific phosphopeptide sequences. Cell 1993; 72: 767-778
-
(1993)
Cell
, vol.72
, pp. 767-778
-
-
Songyang, Z.1
Shoelson, S.E.2
Chaudhuri, M.3
Gish, G.4
Pawson, T.5
Haser, W.6
-
49
-
-
0028351583
-
Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav
-
Songyang Z, Shoelson SE, McGlade J, Olivier P, Pawson T, Bustelo XR et al. Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav. Mol Cell Biol 1994; 14: 2777-2785
-
(1994)
Mol Cell Biol
, vol.14
, pp. 2777-2785
-
-
Songyang, Z.1
Shoelson, S.E.2
McGlade, J.3
Olivier, P.4
Pawson, T.5
Bustelo, X.R.6
-
50
-
-
0028912999
-
Phosphotyrosine-dependent interaction of Shc and insulin receptor substrate-1 with the NPEY motif of the insulin receptor via a novel non-SH2 domain
-
Gustafson TA, He W, Craparo A, Schaub CD, O'Neill TJ. Phosphotyrosine-dependent interaction of Shc and insulin receptor substrate-1 with the NPEY motif of the insulin receptor via a novel non-SH2 domain. Mol Cell Biol 1995; 15: 2500-2508
-
(1995)
Mol Cell Biol
, vol.15
, pp. 2500-2508
-
-
Gustafson, T.A.1
He, W.2
Craparo, A.3
Schaub, C.D.4
O'Neill, T.J.5
-
51
-
-
0028596158
-
An alternative to SH2 domain for binding tyrosine phosphorylated proteins
-
Kavanaugh WM, Williams LT. An alternative to SH2 domain for binding tyrosine phosphorylated proteins. Science 1994; 266: 1862-1865
-
(1994)
Science
, vol.266
, pp. 1862-1865
-
-
Kavanaugh, W.M.1
Williams, L.T.2
-
52
-
-
0029148591
-
Role of IRS-2 in insulin and cytokine signalling
-
Sun XJ, Wang LM, Zhang Y, Yenush L, Myers MG, Glasheen E et al. Role of IRS-2 in insulin and cytokine signalling. Nature 1995; 377: 173-177
-
(1995)
Nature
, vol.377
, pp. 173-177
-
-
Sun, X.J.1
Wang, L.M.2
Zhang, Y.3
Yenush, L.4
Myers, M.G.5
Glasheen, E.6
-
53
-
-
0026437577
-
Crystal structure of a Src-homology 3 (SH3) domain
-
Musacchio A, Noble M, Pauptit R, Wierenga R, Saraste M. Crystal structure of a Src-homology 3 (SH3) domain. Nature 1992; 359: 851-855
-
(1992)
Nature
, vol.359
, pp. 851-855
-
-
Musacchio, A.1
Noble, M.2
Pauptit, R.3
Wierenga, R.4
Saraste, M.5
-
54
-
-
0027245080
-
Crystal structure of the SH3 domain in human fyn - Comparison of the 3-dimensional structures of SH3 domains in tyrosine kinases and spectrin
-
Noble MEM, Musacchio A, Saraste M, Courtneidge SA, Wierenga RK. Crystal structure of the SH3 domain in human fyn - comparison of the 3-dimensional structures of SH3 domains in tyrosine kinases and spectrin. EMBO J 1993; 12: 2617-2624
-
(1993)
EMBO J
, vol.12
, pp. 2617-2624
-
-
Noble, M.E.M.1
Musacchio, A.2
Saraste, M.3
Courtneidge, S.A.4
Wierenga, R.K.5
-
55
-
-
0027102571
-
Solution structure of the SH3 domain of Src and identification of its ligand-binding site
-
Yu H, Rosen MK, Shin TB, Seidel-Dugan C, Brugge JS, Schreiber SL. Solution structure of the SH3 domain of Src and identification of its ligand-binding site. Science 1992; 258: 1665-1668
-
(1992)
Science
, vol.258
, pp. 1665-1668
-
-
Yu, H.1
Rosen, M.K.2
Shin, T.B.3
Seidel-Dugan, C.4
Brugge, J.S.5
Schreiber, S.L.6
-
56
-
-
0027191192
-
Solution structure and ligand-binding site of the SH3 domain of the p85-alpha subunit of phosphatidylinositol 3-kinase
-
Booker GW, Gout I, Downing AK, Driscoll PC, Boyd J, Waterfield MD et al. Solution structure and ligand-binding site of the SH3 domain of the p85-alpha subunit of phosphatidylinositol 3-kinase. Cell 1993; 73: 813-822
-
(1993)
Cell
, vol.73
, pp. 813-822
-
-
Booker, G.W.1
Gout, I.2
Downing, A.K.3
Driscoll, P.C.4
Boyd, J.5
Waterfield, M.D.6
-
57
-
-
0027537997
-
Solution structure of the SH3 domain of phospholipase C-gamma
-
Kohda D, Hatanaka H, Odaka M, Mandiyan V, Ullrich A, Schlessinger J et al. Solution structure of the SH3 domain of phospholipase C-gamma. Cell 1993; 72: 953-960
-
(1993)
Cell
, vol.72
, pp. 953-960
-
-
Kohda, D.1
Hatanaka, H.2
Odaka, M.3
Mandiyan, V.4
Ullrich, A.5
Schlessinger, J.6
-
58
-
-
0027408247
-
Identification of a ten-amino acid proline-rich SH3 binding site
-
Ren R, Mayer BJ, Cicchetti P, Baltimore D. Identification of a ten-amino acid proline-rich SH3 binding site. Science 1993; 259: 1157-1161
-
(1993)
Science
, vol.259
, pp. 1157-1161
-
-
Ren, R.1
Mayer, B.J.2
Cicchetti, P.3
Baltimore, D.4
-
59
-
-
0013484134
-
Structural basis for the binding of proline-rich peptides to SH3 domains
-
Yu H, Chen JK, Feng S, Dalgarno DC, Brauer AW, Schreiber SL. Structural basis for the binding of proline-rich peptides to SH3 domains. Cell 1994; 76: 933-945
-
(1994)
Cell
, vol.76
, pp. 933-945
-
-
Yu, H.1
Chen, J.K.2
Feng, S.3
Dalgarno, D.C.4
Brauer, A.W.5
Schreiber, S.L.6
-
61
-
-
0027945789
-
Crystal structure at 2.2 Å resolution of the pleckstrin homology domain from human dynamin
-
Ferguson KM, Lemmon MA, Schlessinger J, Sigler PB. Crystal structure at 2.2 Å resolution of the pleckstrin homology domain from human dynamin. Cell 1994; 79: 199-209
-
(1994)
Cell
, vol.79
, pp. 199-209
-
-
Ferguson, K.M.1
Lemmon, M.A.2
Schlessinger, J.3
Sigler, P.B.4
-
62
-
-
0028021882
-
Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate
-
Harlan JE, Hajduk PJ, Yoon HS, Fesik SW. Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate. Nature 1994; 371: 168-170
-
(1994)
Nature
, vol.371
, pp. 168-170
-
-
Harlan, J.E.1
Hajduk, P.J.2
Yoon, H.S.3
Fesik, S.W.4
-
63
-
-
0028875162
-
Recognition and specificity in protein tyrosine kinase-mediated signalling
-
Songyang Z, Cantley LC. Recognition and specificity in protein tyrosine kinase-mediated signalling. Trends Biochem Sci 1995; 20: 470-475
-
(1995)
Trends Biochem Sci
, vol.20
, pp. 470-475
-
-
Songyang, Z.1
Cantley, L.C.2
-
65
-
-
0026026818
-
The GTPase superfamily: Conserved structure and molecular mechanism
-
Bourne HR, Sanders DA, McCormick F. The GTPase superfamily: conserved structure and molecular mechanism. Nature 1991; 349: 117-127
-
(1991)
Nature
, vol.349
, pp. 117-127
-
-
Bourne, H.R.1
Sanders, D.A.2
McCormick, F.3
-
66
-
-
0025078512
-
The cellular function of small GTP binding proteins
-
Hall A. The cellular function of small GTP binding proteins. Science 1990; 249: 635-640
-
(1990)
Science
, vol.249
, pp. 635-640
-
-
Hall, A.1
-
67
-
-
0024376173
-
Ras oncogenes in human cancer: A review
-
Bos JL. Ras oncogenes in human cancer: a review. Cancer Res 1989; 49:4682-4689
-
(1989)
Cancer Res
, vol.49
, pp. 4682-4689
-
-
Bos, J.L.1
-
68
-
-
0025838675
-
Regulators and effectors of ras proteins
-
Bollag G, McCormick F. Regulators and effectors of ras proteins. Annu Rev Cell Biol 1991; 7: 601-632
-
(1991)
Annu Rev Cell Biol
, vol.7
, pp. 601-632
-
-
Bollag, G.1
McCormick, F.2
-
71
-
-
0026627960
-
Identification of murine homologues of the Drosophila Son of sevenless gene: Potential activators of ras
-
Bowtell D, Fu P, Simon M, Senior P. Identification of murine homologues of the Drosophila Son of sevenless gene: potential activators of ras. Proc Natl Acad. Sci USA 1992; 89: 6511-6515
-
(1992)
Proc Natl Acad. Sci USA
, vol.89
, pp. 6511-6515
-
-
Bowtell, D.1
Fu, P.2
Simon, M.3
Senior, P.4
-
72
-
-
0026729382
-
The SH2 and SH3 domain-containing proteins GRB2 links receptor tyrosine kinases to ras signalling
-
Lowenstein EJ, Daly RJ, Batzer AG, Li W, Margolis B, Lammers R et al. The SH2 and SH3 domain-containing proteins GRB2 links receptor tyrosine kinases to ras signalling. Cell 1992; 70: 431-442
-
(1992)
Cell
, vol.70
, pp. 431-442
-
-
Lowenstein, E.J.1
Daly, R.J.2
Batzer, A.G.3
Li, W.4
Margolis, B.5
Lammers, R.6
-
73
-
-
0026608178
-
C. elegans cell signaling gene sem-5 encodes a protein with SH2 and SH3 domains
-
Clark SG, Stern MJ, Horvitz HR. C. elegans cell signaling gene sem-5 encodes a protein with SH2 and SH3 domains. Nature 1992; 356: 340-344
-
(1992)
Nature
, vol.356
, pp. 340-344
-
-
Clark, S.G.1
Stern, M.J.2
Horvitz, H.R.3
-
74
-
-
0027468233
-
A Drosophila SH2-SH3 adaptor protein implicated in coupling the sevenless tyrosine kinase to an activator of ras guanine nucleotide exchange, Sos
-
Olivier JP, Raabe T, Henkemeyer M, Dickson B, Mbamalu G, Margolis B et al. A Drosophila SH2-SH3 adaptor protein implicated in coupling the sevenless tyrosine kinase to an activator of ras guanine nucleotide exchange, Sos. Cell 1993; 73: 179-191
-
(1993)
Cell
, vol.73
, pp. 179-191
-
-
Olivier, J.P.1
Raabe, T.2
Henkemeyer, M.3
Dickson, B.4
Mbamalu, G.5
Margolis, B.6
-
75
-
-
0027404990
-
ras1 activation and binds to sevenless and Sos proteins in vitro
-
ras1 activation and binds to sevenless and Sos proteins in vitro. Cell 1993; 73: 169-177
-
(1993)
Cell
, vol.73
, pp. 169-177
-
-
Simon, M.A.1
Dodson, G.S.2
Rubin, G.M.3
-
76
-
-
0027229556
-
Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on Ras
-
Gale NW, Kaplan S, Lowenstein EJ, Schlessinger J, Bar-Sagi D. Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on Ras. Nature 1993; 363: 88-92
-
(1993)
Nature
, vol.363
, pp. 88-92
-
-
Gale, N.W.1
Kaplan, S.2
Lowenstein, E.J.3
Schlessinger, J.4
Bar-Sagi, D.5
-
77
-
-
0027182367
-
The function of Grb2 in linking the insulin receptor to ras signaling pathways
-
Skolnik EY, Batzer A, Li N, Lee CH, Lowenstein E, Mohammadi M et al. The function of Grb2 in linking the insulin receptor to ras signaling pathways. Science 1993; 260: 1953-1955
-
(1993)
Science
, vol.260
, pp. 1953-1955
-
-
Skolnik, E.Y.1
Batzer, A.2
Li, N.3
Lee, C.H.4
Lowenstein, E.5
Mohammadi, M.6
-
78
-
-
0027153103
-
ras through the formation of a complex of receptor, grb2 adapter protein, and SOS nucleotide exchange factor
-
ras through the formation of a complex of receptor, grb2 adapter protein, and SOS nucleotide exchange factor. Cell 1993; 73: 611-620
-
(1993)
Cell
, vol.73
, pp. 611-620
-
-
Buday, L.1
Downward, J.2
-
79
-
-
0027304731
-
Human Sos1: A guanine nucleotide exchange factor for Ras that binds to grb2
-
Chardin P, Camonis JH, Gale NW, Van Aelst L, Schlessinger J, Wigler MH et al. Human Sos1: a guanine nucleotide exchange factor for Ras that binds to grb2. Science 1993; 260: 1338-1343
-
(1993)
Science
, vol.260
, pp. 1338-1343
-
-
Chardin, P.1
Camonis, J.H.2
Gale, N.W.3
Van Aelst, L.4
Schlessinger, J.5
Wigler, M.H.6
-
80
-
-
0027910431
-
Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation
-
Egan SE, Giddings BW, Brooks MW, Buday L, Sizeland AM, Weinberg RA. Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation. Nature 1993; 363: 45-51
-
(1993)
Nature
, vol.363
, pp. 45-51
-
-
Egan, S.E.1
Giddings, B.W.2
Brooks, M.W.3
Buday, L.4
Sizeland, A.M.5
Weinberg, R.A.6
-
81
-
-
0027312272
-
Guanine nucleotide-releasing factor hSOS1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling
-
Li N, Batzer A, Daly R, Yajnik V, Skolnik E, Chardin P et al. Guanine nucleotide-releasing factor hSOS1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling. Nature 1993; 363: 85-88
-
(1993)
Nature
, vol.363
, pp. 85-88
-
-
Li, N.1
Batzer, A.2
Daly, R.3
Yajnik, V.4
Skolnik, E.5
Chardin, P.6
-
82
-
-
0027294981
-
The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSOS1
-
Rozakis-Adcock M, Fernely R, Wade J, Pawson T, Bowtell D. The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSOS1. Nature 1993; 363: 83-85
-
(1993)
Nature
, vol.363
, pp. 83-85
-
-
Rozakis-Adcock, M.1
Fernely, R.2
Wade, J.3
Pawson, T.4
Bowtell, D.5
-
83
-
-
0026777369
-
A novel transforming protein (Shc) with an SH2 domain is implicated in mitogenic signal transduction
-
Pellici G, Lanfrancone L, Grignani F, McGlade J, Cavallo F, Forni G et al. A novel transforming protein (Shc) with an SH2 domain is implicated in mitogenic signal transduction. Cell 1992; 70: 93-104
-
(1992)
Cell
, vol.70
, pp. 93-104
-
-
Pellici, G.1
Lanfrancone, L.2
Grignani, F.3
McGlade, J.4
Cavallo, F.5
Forni, G.6
-
84
-
-
0026678172
-
Association of the Shc and Grb2/Sem-5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases
-
Rozakis-Adcock M, McGlade J, Mbamalu G, Pellici G, Daly R, Schlessinger J et al. Association of the Shc and Grb2/Sem-5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases. Nature 1992; 360: 689-692
-
(1992)
Nature
, vol.360
, pp. 689-692
-
-
Rozakis-Adcock, M.1
McGlade, J.2
Mbamalu, G.3
Pellici, G.4
Daly, R.5
Schlessinger, J.6
-
85
-
-
0027732538
-
Proteins regulating Ras and its relatives
-
Boguski MS, McCormick F. Proteins regulating Ras and its relatives. Nature 1993; 366: 643-654
-
(1993)
Nature
, vol.366
, pp. 643-654
-
-
Boguski, M.S.1
McCormick, F.2
-
86
-
-
0027165150
-
The mitogen-activated protein kinase signal transduction pathway
-
Davis RJ. The mitogen-activated protein kinase signal transduction pathway. J Biol Chem 1993; 268: 14553-14556
-
(1993)
J Biol Chem
, vol.268
, pp. 14553-14556
-
-
Davis, R.J.1
-
87
-
-
0027250250
-
Mammalian Ras interacts directly with the serine/threonine kinase Raf
-
Vojtek AB, Hollenberg SM, Cooper JA. Mammalian Ras interacts directly with the serine/threonine kinase Raf. Cell 1993; 74: 205-214
-
(1993)
Cell
, vol.74
, pp. 205-214
-
-
Vojtek, A.B.1
Hollenberg, S.M.2
Cooper, J.A.3
-
89
-
-
0027200883
-
Direct interaction of Ras and the amino-terminal region of raf-1 in vitro
-
Warne PH, Rodriguez-Viciana P, Downward J. Direct interaction of Ras and the amino-terminal region of raf-1 in vitro. Nature 1993; 364: 352-355
-
(1993)
Nature
, vol.364
, pp. 352-355
-
-
Warne, P.H.1
Rodriguez-Viciana, P.2
Downward, J.3
-
90
-
-
0028168320
-
Raf: The holy grail of Ras biology?
-
McCormick F. Raf: the holy grail of Ras biology ? Trends Cell Biol 1994; 4: 347-350
-
(1994)
Trends Cell Biol
, vol.4
, pp. 347-350
-
-
McCormick, F.1
-
91
-
-
0028272507
-
Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane
-
Leevers SJ, Paterson HF, Marshall CJ. Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane. Nature 1994; 369: 411-414
-
(1994)
Nature
, vol.369
, pp. 411-414
-
-
Leevers, S.J.1
Paterson, H.F.2
Marshall, C.J.3
-
92
-
-
0028241533
-
Activation of Raf as a result of recruitment to the plasma membrane
-
Stokoe D, MacDonald SG, Cadwallader K, Symons M, Hancock JF. Activation of Raf as a result of recruitment to the plasma membrane. Science 1994; 264: 1463-1467
-
(1994)
Science
, vol.264
, pp. 1463-1467
-
-
Stokoe, D.1
MacDonald, S.G.2
Cadwallader, K.3
Symons, M.4
Hancock, J.F.5
-
93
-
-
0026647749
-
Raf-1 activates MAP kinase kinase
-
Kyriakis JM, App H, Zhang XF, Banerjee P, Brautigan DL, Rapp UR et al. Raf-1 activates MAP kinase kinase. Nature 1992; 358: 417-421
-
(1992)
Nature
, vol.358
, pp. 417-421
-
-
Kyriakis, J.M.1
App, H.2
Zhang, X.F.3
Banerjee, P.4
Brautigan, D.L.5
Rapp, U.R.6
-
94
-
-
0028293931
-
Identification of the sites in MAP kinase kinase-1 phosphorylated by p74raf-1
-
Alessi DR, Saito Y, Campbell DC, Cohen P, Sithanandam G, Rapp U et al. Identification of the sites in MAP kinase kinase-1 phosphorylated by p74raf-1. EMBO J 1994; 13: 1610-1619
-
(1994)
EMBO J
, vol.13
, pp. 1610-1619
-
-
Alessi, D.R.1
Saito, Y.2
Campbell, D.C.3
Cohen, P.4
Sithanandam, G.5
Rapp, U.6
-
95
-
-
0028329630
-
Activation of MEK family kinases requires phosphorylation of two conserved Ser/Thr residues
-
Zheng CF, Guan KL. Activation of MEK family kinases requires phosphorylation of two conserved Ser/Thr residues. EMBO J 1994; 13: 1123-1131
-
(1994)
EMBO J
, vol.13
, pp. 1123-1131
-
-
Zheng, C.F.1
Guan, K.L.2
-
96
-
-
0028872649
-
Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-related kinase activation
-
Marshall CJ. Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-related kinase activation. Cell 1995; 80: 179-185
-
(1995)
Cell
, vol.80
, pp. 179-185
-
-
Marshall, C.J.1
-
97
-
-
0029130317
-
Desensitization of Ras activation by a feed back dissociation of the Sos/Grb2 complex
-
Waters SB, Holt KH, Ross SE, Syu LJ, Guan KL, Saltiel AR et al. Desensitization of Ras activation by a feed back dissociation of the Sos/Grb2 complex. J Biol Chem 1995; 270: 20883-20886
-
(1995)
J Biol Chem
, vol.270
, pp. 20883-20886
-
-
Waters, S.B.1
Holt, K.H.2
Ross, S.E.3
Syu, L.J.4
Guan, K.L.5
Saltiel, A.R.6
-
98
-
-
0028073283
-
MAPKs: New JNK expands the group
-
Davis RJ. MAPKs: new JNK expands the group. Trends Biochem Sci 1994; 19: 470-473
-
(1994)
Trends Biochem Sci
, vol.19
, pp. 470-473
-
-
Davis, R.J.1
-
99
-
-
0029055812
-
The small GTP-binding prteins Rac1 and cdc42 regulate the activity of the JNK/SAPK signaling pathway
-
Coso OA, Chiariello M, Yu JC, Teramoto H, Crespo P, Xu N et al. The small GTP-binding prteins Rac1 and cdc42 regulate the activity of the JNK/SAPK signaling pathway. Cell 1995; 81: 1137-1146
-
(1995)
Cell
, vol.81
, pp. 1137-1146
-
-
Coso, O.A.1
Chiariello, M.2
Yu, J.C.3
Teramoto, H.4
Crespo, P.5
Xu, N.6
-
100
-
-
0029070887
-
Selective activation of the JNK signaling cascade and c-jun transcriptional activity by the small GTPases Rac and Cdc42Hs
-
Minden A, Lin A, Claret FX, Abo A, Karin M. Selective activation of the JNK signaling cascade and c-jun transcriptional activity by the small GTPases Rac and Cdc42Hs. Cell 1995; 81: 1147-1157
-
(1995)
Cell
, vol.81
, pp. 1147-1157
-
-
Minden, A.1
Lin, A.2
Claret, F.X.3
Abo, A.4
Karin, M.5
-
101
-
-
0024043851
-
Purification of ras GTPase activating protein from bovine brain
-
Gibbs JB, Schaber MD, Allard WJ, Sigal IS, Scolnick EM. Purification of ras GTPase activating protein from bovine brain. Proc Natl Acad Sci USA 1988; 85: 5026-5030
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 5026-5030
-
-
Gibbs, J.B.1
Schaber, M.D.2
Allard, W.J.3
Sigal, I.S.4
Scolnick, E.M.5
-
102
-
-
0023619575
-
A cytoplasmic protein stimulates normal N-ras p21GTPase but does not affect oncogenic mutants
-
Trahey M, McCormick F. A cytoplasmic protein stimulates normal N-ras p21GTPase but does not affect oncogenic mutants. Science 1987; 238: 542-545
-
(1987)
Science
, vol.238
, pp. 542-545
-
-
Trahey, M.1
McCormick, F.2
-
104
-
-
0025177324
-
Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases
-
Ellis C, Moran M, McCormick F, Pawson T. Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases. Nature 1990; 343: 377-381
-
(1990)
Nature
, vol.343
, pp. 377-381
-
-
Ellis, C.1
Moran, M.2
McCormick, F.3
Pawson, T.4
-
106
-
-
0026778344
-
GTPase activing protein SH2-SH3 domains induce gene expression in a Ras dependent fashion
-
Medema RH, de Laat WL, Martin GA, McCormick F, Bos JL. GTPase activing protein SH2-SH3 domains induce gene expression in a Ras dependent fashion. Mol Cell Biol 1992; 12: 3425-3430
-
(1992)
Mol Cell Biol
, vol.12
, pp. 3425-3430
-
-
Medema, R.H.1
De Laat, W.L.2
Martin, G.A.3
McCormick, F.4
Bos, J.L.5
-
107
-
-
0026697169
-
Molecular cloning and nucleic acid binding of the GAP-associated tyrosine phosphoprotein p62
-
Wong G, Müller O, Clark R, Conroy L, Moran MF, Polakis P et al. Molecular cloning and nucleic acid binding of the GAP-associated tyrosine phosphoprotein p62. Cell 1992; 69: 551-558
-
(1992)
Cell
, vol.69
, pp. 551-558
-
-
Wong, G.1
Müller, O.2
Clark, R.3
Conroy, L.4
Moran, M.F.5
Polakis, P.6
-
108
-
-
0026740716
-
Molecular cloning of cDNAs encoding GAP-associated protein p190: Implications for a signaling pathway from Ras to the nucleus
-
Settleman J, Narasimhan V, Foster LC, Weinberg RA. Molecular cloning of cDNAs encoding GAP-associated protein p190: implications for a signaling pathway from Ras to the nucleus. Cell 1992; 69: 539-549
-
(1992)
Cell
, vol.69
, pp. 539-549
-
-
Settleman, J.1
Narasimhan, V.2
Foster, L.C.3
Weinberg, R.A.4
-
110
-
-
0027296039
-
The N-terminal region of GAP regulates cytoskeletal structure and cell adhesion
-
McGlade J, Brunkhorst B, Anderson D, Mbamalu G, Settlleman J, Dedhar S et al. The N-terminal region of GAP regulates cytoskeletal structure and cell adhesion. EMBO J 1993; 12: 3073-3081
-
(1993)
EMBO J
, vol.12
, pp. 3073-3081
-
-
McGlade, J.1
Brunkhorst, B.2
Anderson, D.3
Mbamalu, G.4
Settlleman, J.5
Dedhar, S.6
-
111
-
-
0027953284
-
PI 3-kinase is a dual-specificity enzyme: Autoregulationby an intrinsic protein-serine kinase activity
-
Dhand R, Hiles I, Panayotou G, Roche S, Fry MJ, Gout I et al. PI 3-kinase is a dual-specificity enzyme: autoregulationby an intrinsic protein-serine kinase activity. EMBO J 1994; 13: 522-533
-
(1994)
EMBO J
, vol.13
, pp. 522-533
-
-
Dhand, R.1
Hiles, I.2
Panayotou, G.3
Roche, S.4
Fry, M.J.5
Gout, I.6
-
112
-
-
0028856331
-
When is a lipid kinase not a lipid kinase? When it is a protein kinase
-
Hunter T. When is a lipid kinase not a lipid kinase ? When it is a protein kinase. Cell 1995; 83: 1-4
-
(1995)
Cell
, vol.83
, pp. 1-4
-
-
Hunter, T.1
-
113
-
-
0027925818
-
Structure and function of phosphatidylinositol 3-kinase: A potential second messenger system involved in growth control
-
Fry MJ, Waterfield MD. Structure and function of phosphatidylinositol 3-kinase: a potential second messenger system involved in growth control. Phil Trans R Soc Lond B 1993; 340: 337-344
-
(1993)
Phil Trans R Soc Lond B
, vol.340
, pp. 337-344
-
-
Fry, M.J.1
Waterfield, M.D.2
-
114
-
-
0027211693
-
Phospholipase C-gamma 1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic
-
Valius M, Kazlauskas A. Phospholipase C-gamma 1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic. Cell 1993; 74: 321-334
-
(1993)
Cell
, vol.74
, pp. 321-334
-
-
Valius, M.1
Kazlauskas, A.2
-
115
-
-
0028308412
-
Phosphatidylinositol 3-kinase is required for insulin stimulation of pp70 S6 kinase, DNA synthesis and glucose transporter translocation
-
Cheatham B, Vlahos CJ, Cheatham L, Wang L, Blenis J, Kahn CR. Phosphatidylinositol 3-kinase is required for insulin stimulation of pp70 S6 kinase, DNA synthesis and glucose transporter translocation. Mol Cell Biol 1994; 14: 4902-4911
-
(1994)
Mol Cell Biol
, vol.14
, pp. 4902-4911
-
-
Cheatham, B.1
Vlahos, C.J.2
Cheatham, L.3
Wang, L.4
Blenis, J.5
Kahn, C.R.6
-
116
-
-
0028838845
-
A target for phosphoinositide 3-kinase: Akt/PKB
-
Bos JL. A target for phosphoinositide 3-kinase: Akt/PKB. Trends Biochem Sci 1995; 20: 441-442
-
(1995)
Trends Biochem Sci
, vol.20
, pp. 441-442
-
-
Bos, J.L.1
-
117
-
-
0028178928
-
PDGF-dependent regulation of pp70-S6 kinase is coupled to receptor-dependent binding and activation of phosphatidylinositol 3-kinase
-
Chung J, Grammar TC, Lemon KP, Kazlauskas A, Blenis J. PDGF-dependent regulation of pp70-S6 kinase is coupled to receptor-dependent binding and activation of phosphatidylinositol 3-kinase. Nature 1994; 370: 71-75
-
(1994)
Nature
, vol.370
, pp. 71-75
-
-
Chung, J.1
Grammar, T.C.2
Lemon, K.P.3
Kazlauskas, A.4
Blenis, J.5
-
118
-
-
0028022798
-
Regulating S6 kinase
-
Downward J. Regulating S6 kinase. Nature 1994; 371: 378-379
-
(1994)
Nature
, vol.371
, pp. 378-379
-
-
Downward, J.1
-
119
-
-
0027170920
-
SH3 domains direct cellular localization of signaling molecules
-
Bar Sagi D, Rotin D, Batzer A, Mandiyan V, Schlessinger J. SH3 domains direct cellular localization of signaling molecules. Cell 1993; 74: 83-91
-
(1993)
Cell
, vol.74
, pp. 83-91
-
-
Bar Sagi, D.1
Rotin, D.2
Batzer, A.3
Mandiyan, V.4
Schlessinger, J.5
-
120
-
-
0024473908
-
Protein tyrosine phosphatases: The other side of the coin
-
Hunter T. Protein tyrosine phosphatases: the other side of the coin. Cell 1989; 58: 1013-1016
-
(1989)
Cell
, vol.58
, pp. 1013-1016
-
-
Hunter, T.1
-
121
-
-
0028009549
-
Protein tyrosine phosphatases: Characterization of extracellular and intracellular domains
-
Mourey RJ, Dixon JE. Protein tyrosine phosphatases: characterization of extracellular and intracellular domains. Curr Opin Genet Dev 1994; 4: 31-39
-
(1994)
Curr Opin Genet Dev
, vol.4
, pp. 31-39
-
-
Mourey, R.J.1
Dixon, J.E.2
-
122
-
-
0025816584
-
A protein tyrosine phospahatase with sequence similarity to the SH2 domain of the protein tyrosine kinases
-
Shen SH, Bastien L, Posner BI, Chretien P. A protein tyrosine phospahatase with sequence similarity to the SH2 domain of the protein tyrosine kinases. Nature 1991; 352: 736-739
-
(1991)
Nature
, vol.352
, pp. 736-739
-
-
Shen, S.H.1
Bastien, L.2
Posner, B.I.3
Chretien, P.4
-
123
-
-
0027399168
-
Activation of a phosphotyrosine phosphatase by tyrosine phosphorylation
-
Vogel W, Lammers R, Huang J, Ullrich A. Activation of a phosphotyrosine phosphatase by tyrosine phosphorylation. Science 1993; 259: 1611-1614
-
(1993)
Science
, vol.259
, pp. 1611-1614
-
-
Vogel, W.1
Lammers, R.2
Huang, J.3
Ullrich, A.4
-
124
-
-
0028179013
-
Protein tyrosine phosphatase SHPTP2 couples platelet derived growth factor beta to Ras
-
Bennet AM, Tang TL, Sugimoto S, Walsh CT, Neel BG. Protein tyrosine phosphatase SHPTP2 couples platelet derived growth factor beta to Ras. Proc Natl Acad Sci USA 1994; 91: 7335-7339
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 7335-7339
-
-
Bennet, A.M.1
Tang, T.L.2
Sugimoto, S.3
Walsh, C.T.4
Neel, B.G.5
-
125
-
-
0028123457
-
A new function for a phosphotyrosine phosphatase: Linking Grb2-Sos to a receptor tyrosine kinase
-
Li W, Nishimura R, Kashishian A, Batzer AG, Kim WJ, Cooper JA et al. A new function for a phosphotyrosine phosphatase: linking Grb2-Sos to a receptor tyrosine kinase. Mol Cell Biol 1994; 14: 509-517
-
(1994)
Mol Cell Biol
, vol.14
, pp. 509-517
-
-
Li, W.1
Nishimura, R.2
Kashishian, A.3
Batzer, A.G.4
Kim, W.J.5
Cooper, J.A.6
-
126
-
-
0028124504
-
Role of SH-PTP2, a protein tyrosine phosphatase with Src homology 2 domains in insulin-stimulated Ras activation
-
Noguchi T, Matozaki T, Horita K, Fujijoka Y, Kasuga M. Role of SH-PTP2, a protein tyrosine phosphatase with Src homology 2 domains in insulin-stimulated Ras activation. Mol Cell Biol 1994; 14: 6674-6682
-
(1994)
Mol Cell Biol
, vol.14
, pp. 6674-6682
-
-
Noguchi, T.1
Matozaki, T.2
Horita, K.3
Fujijoka, Y.4
Kasuga, M.5
-
127
-
-
0028896991
-
Protein tyrosine phosphaste SH-PTP2 is a required positive effector of insulin downstream signaling
-
Yamauchi K, Milarski KL, Saltiel AR, Pessin J. Protein tyrosine phosphaste SH-PTP2 is a required positive effector of insulin downstream signaling. Proc Natl Acad Sci USA 1995; 92: 664-668
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 664-668
-
-
Yamauchi, K.1
Milarski, K.L.2
Saltiel, A.R.3
Pessin, J.4
-
128
-
-
0026069474
-
Oncogenes and signal transduction
-
Cantley LC, Auger KR, Carpenter C, Duckworth B, Graziani A, Kapeller R et al. Oncogenes and signal transduction. Cell 1991; 64: 281-302
-
(1991)
Cell
, vol.64
, pp. 281-302
-
-
Cantley, L.C.1
Auger, K.R.2
Carpenter, C.3
Duckworth, B.4
Graziani, A.5
Kapeller, R.6
-
130
-
-
0026612830
-
Role of p34cdc2-mediated phosphorylations in two step activation of pp60-c-src during mitosis
-
Shenoy S, Chachalaparampil I, Bagrodia S, Lin PH, Shalloway D. Role of p34cdc2-mediated phosphorylations in two step activation of pp60-c-src during mitosis. Proc Natl Acad Sci USA 1992; 89: 7237-7241
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 7237-7241
-
-
Shenoy, S.1
Chachalaparampil, I.2
Bagrodia, S.3
Lin, P.H.4
Shalloway, D.5
-
131
-
-
0026674919
-
Focal adhesion protein tyrosine kinase phosphorylated in response to cell spreading on fibronectin
-
Hanks SK, Calalb MB, Harper MC, Patel SK. Focal adhesion protein tyrosine kinase phosphorylated in response to cell spreading on fibronectin. Proc Natl Acad Sci USA 1992; 89: 8487-8489
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 8487-8489
-
-
Hanks, S.K.1
Calalb, M.B.2
Harper, M.C.3
Patel, S.K.4
-
132
-
-
0026612521
-
FAK, a structurally unique protein kinase associated with focal adhesions
-
FAK, a structurally unique protein kinase associated with focal adhesions. Proc Natl Acad Sci USA 1992; 89:5192-5196
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 5192-5196
-
-
Schaller, M.D.1
Borgman, C.A.2
Cobb, B.S.3
Vines, R.R.4
Reynolds, A.B.5
Parsons, J.T.6
-
134
-
-
0028987936
-
Integrins and signal transduction pathways: The road taken
-
Clark EA, Brugge JS. Integrins and signal transduction pathways: the road taken. Science 1995; 268: 223-229
-
(1995)
Science
, vol.268
, pp. 223-229
-
-
Clark, E.A.1
Brugge, J.S.2
-
135
-
-
13344270369
-
The molecular architecture of focal adhesions
-
Jokusch BM, Bubeck P, Giehl K, Kroemker M, Moschner J, Rothkegel M et al. The molecular architecture of focal adhesions. Annu Rev Cell Biol 1995; 11: 379-416
-
(1995)
Annu Rev Cell Biol
, vol.11
, pp. 379-416
-
-
Jokusch, B.M.1
Bubeck, P.2
Giehl, K.3
Kroemker, M.4
Moschner, J.5
Rothkegel, M.6
-
136
-
-
0023834406
-
A cascade of tyrosine phosphorylation in the beta-subunit activates the phosphotransferase of the insulin receptor
-
White MF, Shoelson SE, Keutmann H, Kahn CR. A cascade of tyrosine phosphorylation in the beta-subunit activates the phosphotransferase of the insulin receptor. J Biol Chem 1988; 263: 2969-2980
-
(1988)
J Biol Chem
, vol.263
, pp. 2969-2980
-
-
White, M.F.1
Shoelson, S.E.2
Keutmann, H.3
Kahn, C.R.4
-
137
-
-
0023244139
-
Identification of the insulin receptor tyrosine residues autophosphorylated in vitro
-
Tornqvist HE, Pierce MW, Frackelton HR, Nemenoff RA, Avruch I. Identification of the insulin receptor tyrosine residues autophosphorylated in vitro. J Biol Chem 1987; 262: 10212-10219
-
(1987)
J Biol Chem
, vol.262
, pp. 10212-10219
-
-
Tornqvist, H.E.1
Pierce, M.W.2
Frackelton, H.R.3
Nemenoff, R.A.4
Avruch, I.5
-
138
-
-
0023882103
-
Identifcation of the insulin receptor tyrosine residues undergoing insulin-stimulated phosphorylation in intact rat hepatoma cell
-
Tornqvist HE, Gunsalus JR, Nemenoff RA, Frackelton RA, Pierce MW, Avruch J. Identifcation of the insulin receptor tyrosine residues undergoing insulin-stimulated phosphorylation in intact rat hepatoma cell. J Biol Chem 1988; 263: 350-359
-
(1988)
J Biol Chem
, vol.263
, pp. 350-359
-
-
Tornqvist, H.E.1
Gunsalus, J.R.2
Nemenoff, R.A.3
Frackelton, R.A.4
Pierce, M.W.5
Avruch, J.6
-
139
-
-
0025813375
-
Structure of the insulin receptor substrate (IRS-1) defines an unique signal transduction protein
-
Sun XJ, Rothenberg P, Kahn CR, Backer JM, Araki E, Wilden PA et al. Structure of the insulin receptor substrate (IRS-1) defines an unique signal transduction protein. Nature 1991; 352: 73-77
-
(1991)
Nature
, vol.352
, pp. 73-77
-
-
Sun, X.J.1
Rothenberg, P.2
Kahn, C.R.3
Backer, J.M.4
Araki, E.5
Wilden, P.A.6
-
140
-
-
0027466903
-
Insulin-induced phosphorylation of the 46 and 52 kD Shc proteins
-
Pronk GJ, McGlade J, Pelicci G, Pawson T, Bos JL. Insulin-induced phosphorylation of the 46 and 52 kD Shc proteins. J Biol Chem 1993; 268: 5748-5753
-
(1993)
J Biol Chem
, vol.268
, pp. 5748-5753
-
-
Pronk, G.J.1
McGlade, J.2
Pelicci, G.3
Pawson, T.4
Bos, J.L.5
-
145
-
-
0028297696
-
Activation of the Ras/mitogen activated protein kinase signaling pathway alone is not sufficient to induce glucose uptake in 3T3L1 adipocytes
-
Van den Berghe N, Ouwens DM, Maassen JA, van Mackelenbergh MGH, Sips HCM, Krans HMJ. Activation of the Ras/mitogen activated protein kinase signaling pathway alone is not sufficient to induce glucose uptake in 3T3L1 adipocytes. Mol Cell Biol 1994; 14: 2372-2377
-
(1994)
Mol Cell Biol
, vol.14
, pp. 2372-2377
-
-
Van Den Berghe, N.1
Ouwens, D.M.2
Maassen, J.A.3
Van Mackelenbergh, M.G.H.4
Sips, H.C.M.5
Krans, H.M.J.6
-
147
-
-
0029924465
-
Expression of a dominant-negative Ras mutant does not affect stimulation of glucose uptake and glycogen synthesis by insulin
-
In press
-
Dorrestijn J, Ouwens DM, van den Berghe N, Bos JL, Maassen JA. Expression of a dominant-negative Ras mutant does not affect stimulation of glucose uptake and glycogen synthesis by insulin. Diabetologia 1996; 39: In press
-
(1996)
Diabetologia
, vol.39
-
-
Dorrestijn, J.1
Ouwens, D.M.2
Van Den Berghe, N.3
Bos, J.L.4
Maassen, J.A.5
-
148
-
-
0028837993
-
Insulin stimulates the tyrosine dephosphorylation of pp125 Focal Adhesion Kinase
-
Pillay TS, Sasaoka T, Olefsky JM. Insulin stimulates the tyrosine dephosphorylation of pp125 Focal Adhesion Kinase. J Biol Chem 1995; 270: 991-994
-
(1995)
J Biol Chem
, vol.270
, pp. 991-994
-
-
Pillay, T.S.1
Sasaoka, T.2
Olefsky, J.M.3
-
149
-
-
33750384572
-
-
Submitted for publication
-
Ouwens DM, Mikkers HMM, van der Zon GCM, Stein-Gerlach M, Ullrich A, Maassen JA. Insulin-induced tyrosine dephosphorylation of focal adhesion kinase and paxillin requires active phosphotyrosine phosphatase 1D. Submitted for publication
-
Insulin-induced Tyrosine Dephosphorylation of Focal Adhesion Kinase and Paxillin Requires Active Phosphotyrosine Phosphatase 1D
-
-
Ouwens, D.M.1
Mikkers, H.M.M.2
Van Der Zon, G.C.M.3
Stein-Gerlach, M.4
Ullrich, A.5
Maassen, J.A.6
|