Psychoneuroimmunology: Animal models of disease

Psychosomatic Medicine

Volumn 58, Issue 6, 1996, Pages 546-558

  Moynihan, Jan A ^a,b   Ader, Robert ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

animal models; behavioral conditioning; infectious disease; psychoneuroimmunology; stress; T helper cell subsets

Indexed keywords

CORTICOSTERONE; GLUCOCORTICOID;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ATHEROSCLEROSIS; COXSACKIE VIRUS; HELICOBACTER PYLORI; INFLUENZA; INSULIN DEPENDENT DIABETES MELLITUS; METASTASIS POTENTIAL; MOUSE; MYCOBACTERIOSIS; NEUROIMMUNOLOGY; NONHUMAN; PATHOGENESIS; PEPTIC ULCER; PRIORITY JOURNAL; PSYCHOPHYSIOLOGY; REVIEW; RHEUMATOID ARTHRITIS; SOCIAL PSYCHOLOGY; SYSTEMIC LUPUS ERYTHEMATOSUS; TREATMENT OUTCOME;

EID: 0029805171     PISSN: 00333174     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006842-199611000-00003     Document Type: Review

References (114)

1. Ader R, Felten DL, Cohen N (eds): Psychoneuroimmunology, 2nd Ed. New York, Academic Press, 1991
2. Kiecolt-Glaser JK, Malarkey WB, Cacioppo JT, et al : Stressful personal relationships: Immune and endocrine function. In Glaser R, Kiecolt-Glaser JK (eds), Handbook of Human Stress and Immunity. New York, Academic Press, 1994, 321-339
3. Kiecolt-Glaser JK, Glaser R: Stress and immune function. In Ader R, Felten DL, Cohen N (eds). Psychoneuroimmunology, 2d Ed. New York, Academic Press, 1991, 849-868
4. Kemeny ME, Solomon GF, Morley JE, et al: Psychoneuroimmunology. In Nemeroff CB (ed), Neuroendocrinology. Boca Raton, CRC Press, Inc, 1993, 563-591
5. O'Leary A: Stress, emotion, and human immune function. Psychol Bull 108:363-382, 1990
6. Cohen S, Williamson GM: Stress and infectious disease in humans. Psychol Bull 109:5-24, 1991
7. Cohen S: Psychosocial influences on immunity and infectious disease in humans. In Glaser R, Kiecolt-Glaser JK (eds), Handbook of Human Stress and Immunity. New York, Academic Press, 1994, 301-319
8. Cohen S, Tyrrell AAJ, Smith AP: Psychological stress and susceptibility to the common cold. N Engl J Med 325:606-612, 1991
9. Levy SM, Herberman RB, Whiteside T, et al: Perceived social support and tumor estrogen/progesterone receptor status as predictors of natural killer cell activity in breast cancer patients. Psychosom Med 52:73-85, 1990
10. Levy SM, Herberman RB, Lee J, et al: Persistently low natural killer cell activity, age, and environmental stress as predictors of infectious morbidity. Natl Immun 10:289-307, 1991
11. Fawzy FI, Fawzy NW: Psychoeducational interventions and health outcomes. In Glaser R, Kiecolt-Glaser JK (eds), Hand-book of Human Stress and Immunity. New York, Academic Press, 1994, 365-402
12. Fawzy FI, Fawzy NW, Hyun CS, et al: Effects of an early structured psychiatric intervention, coping, and affective state on recurrence and survival 6 years later. Arch Gen Psychiatry 50:681-689, 1993
13. Spiegel D, Bloom JR, Kraemer HC, et al: Effect of psychosocial treatment on survival of patients with metastatic breast cancer. Lancet 8668:888-891, 1989
14. Scott P: Selective differentiation of CD4+ T helper cell subsets. Curr Opin Immunol 5:391-397, 1993
15. Reed SG, Scott P: T-cell and cytokine responses in leishmaniasis. Curr Opin Immunol 5:524-531, 1993
16. Modlin RL, Nutman TB: Type 2 cytokines and negative immune regulation in human infections. Curr Opin Immunol 5:511-517, 1993
17. Paul WE, Seder RA: Lymphocyte responses and cytokines. Cell 76:241-251, 1994
18. Powrie F, Coffman RL: Cytokine regulation of T-cell function: potential for therapeutic intervention. Immunol Today 14:270-274, 1993
19. Golding B, Zaitseva M, Golding H: The potential for recruiting immune responses toward type 1 or type 2 T cell help. Am J Trop Med Hyg 50(Suppl):33-40, 1993
20. Sadick MD, Heinzel FP, Holaday BJ, et al: Cure of murine Leishmaniasis with anti-interleukin 4 monoclonal antibody. J Exp Med 171:115-127, 1990
21. Heinzel FP, Sadick MD, Holaday BJ, et al: Reciprocal expression of Interferon γ or interleukin 4 during the resolution of murine Leishmaniasis. J Exp Med 169:59-72, 1989
22. Bretscher PA, Wei G, Menjon JN, et al: Establishment of stable, cell-mediated immunity that makes 'susceptible' mice resistant to Leishmania major. Science 257, 539-542, 1992
23. Belosevic M, Finbloom DS, van der Meade P, et al: Administration of monoclonal anti-IFN-γ antibodies in vivo abrogates natural resistance of C3H/HeN mice to infection with Leishmania major. J Immunol 143:266-274, 1989
24. Araneo B, Woods ML, Daynes RA: Reversal of the immunoscenescent phenotype by dihydroepiandrosterone: Hormone treatment provides an adjuvant effect on the immunization of aged mice with recombinant hepatitis B surface antigen. J Infect Dis 167:830-840, 1993
25. Daynes RA, Araneo BA: Contrasting effects of glucocorticoids on the capacity of T cells to produce the growth factors interleukin 2 and interleukin 4. Eur J Immunol 19:2319-2325, 1989
26. Meikle AW, Daynes RA, Araneo BA: Adrenal androgen secretion and biologic effects. Endocrinol Metab Clin North Am20:381-400, 1991
27. McCombe PA, de Jersey J, Pender MP: Inflammatory cells, microglia and MHC class II antigen-positive cells in the spinal cord of Lewis rats with acute and chronic relapsing experimental autoimmune encephalomyelitis. J Neuroimmunol 51:153-167, 1994
28. Kennedy MK, Torrance DS, Picha KS, et al: Analysis of cytokine mRNA expression in the central nervous system of mice with experimental autoimmune encephalomyelitis reveals that IL-10 mRNA expression correlates with recovery. J Immunol 149:2496-2505, 1992
29. Levine S, Strebel R, Wenk EJ, et al: Suppression of experimental allergic encephalomyelitis by stress. Proc Soc Exp Biol Med 109:294-298, 1962
30. Griffin AC, Lo WD, Wolny AC, et al: Suppression of experimental autoimmune encephalomyelitis by restraint stress: Sex differences. J Neuroimmunol 44:103-116, 1993
31. Kuroda Y, Mori T, Hori T: Restraint stress suppresses experimental allergic encephalomyelitis in Lewis rats. Brain Res Bull 34:15-17, 1994
32. Levine S, Saltzman A: Nonspecific stress prevents relapses in experimental allergic encephalomyelitis in rats. Brain Behav Immun 1:336-341, 1987
33. Bukilica M, Djordjevic S, Maric I, et al: Stress-induced suppression of experimental allergic encephalomyelitis in the rat. Int J Neurosci 59:167-175, 1991
34. Levine S, Strebel R: Allergic encephalomyelitis: Inhibition of cellular passive transfer by exogenous and endogenous steroids. Experientia 25:189-190, 1969
35. MacPhee IAM, Antoni FA, Mason D: Spontaneous recovery of rats from experimental allergic encephalomyelitis is dependent on regulation of the immune system by endogenous adrenal corticosteroids. J Exp Med 169:431-445, 1989
36. Mason D, MacPhee I, Antoni F: The role of the neuroendocrine system in determining genetic susceptibility to experimental allergic encephalomyelitis in the rat. Immunology 70:1-5, 1990
37. Jankovic BD, Maric D: Enkephalins and autoimmunity: Differential effect of methionine-enkephalin on experimental allergic encephalomyelitis in Wistar and Lewis rats. J Neurosci Res 18:88-94, 1987
38. Liblau RS, Singer SM, McDevitt HO: Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases. Immunol Today 16:34-38, 1995
39. Khoury SJ, Hancock WW, Weiner HL: Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encephlalomyelitis are associated with down-regulation of inflammatory cytokines and differential up-regulation of transforming growth factor ß, interleukin 4, and prostaglandin E expression in the brain. J Exp Med 176: 1355-1364, 1992
40. MacPhee IAM, Day MJ, Mason DW: The role of serum factors in the suppression of experimental allergic encephalomyelitis: Evidence for immunoregulation by antibody to the encephalitogenic peptide. Immunology 70:527-534, 1992
41. Mason D: Genetic variation in the stress response: Susceptibility to experimental allergic encephalomyelitis and implications for human inflammatory disease. Immunol Today 12:57-60, 1992
42. Munck A, Guyre PM: Glucocorticoids and immune function. In Ader R, Felten DL, Cohen N (eds), Psychoneuroimmunology, 2nd Ed. New York, Academic Press, 1991, 447-474
43. Bidlack JM, Saripalli LD, Lawrence DMP: κ-Opioid binding sites on a murine lymphoma cell line. Eur J Pharmacol 227:257-265, 1992
44. Rogers MP, Trentham DE, McCune WJ, et al: Effect of psychological stress on the induction of arthritis in rats. Arthritis Rheum 23:1337-1342, 1980
45. Lysle DL, Luecken LJ, Maslonek KA: Suppression of the development of adjuvant arthritis by a conditioned aversive stimulus. Brain Behav Immun 6:64-73, 1992
46. Sternberg EM, Glowa JR, Smith MA, et al: Corticotropin-releasing hormone related behavioral and neuroendocrine responses to stress in Lewis and Fischer rats. Brain Res 570:54-60, 1992
47. Sternberg EM, Wilder RL: The role of the hypothalamicpituitary-adrenal axis in an experimental model of arthritis. PNEI (Psychoneuroendocrinolimmunol) 2:102-108, 1989
48. Aksentijevich S, Whitfield HJ, Young WS, et al: Arthritis-susceptible Lewis rats fail to emerge from the stress hyporesponsive period. Dev Brain Res 65:115-118, 1992
49. Zelazowski P, Patchev VK, Zelazowska EB, et al: Release of hypothalamic corticotropin-releasing hormone and arginine-vasopressin by interleukin 1β and αMSH: studies in rats with different susceptibility to inflammatory disease. Brain Res 631:22-26, 1993
50. Zelazowski P, Smith MA, Gold PW, et al: In vitro regulation of pituitary ACTH secretion in inflammatory disease susceptible Lewis (LEW/N) and inflammatory disease resistant Fischer (F344/N) rats. Neuroendocrinology 56:474-482, 1992
51. Levine JD, Clark R, Devor M, et al: Intraneuronal substance P contributes to the severity of experimental arthritis. Science 226:547-549, 1984
52. Robinson CE: Emotional factors and rheumatoid arthritis. Can Med Assoc J 77:344-345, 1957
53. Sochet BR, Lisansky ET, Schubart AF, et al: A medical-psychiatric study of patients with rheumatoid arthritis. Psychosomatics 10:271-279, 1969
54. Amkraut AA, Solomon GF, Kraemer HC: Stress, early experience and adjuvant-induced arthritis in the rat. Psychosom Med 33:203-214, 1971
55. Klosterhalfen W, Klosterhalfen S: Pavlovian conditioning of immunosuppression modifies adjuvant arthritis in rats. Behav Neurosci 97:663-666, 1983
56. Klosterhalfen S, Klosterhalfen W: Conditioned cyclosporin effects but not conditioned taste aversion in immunized rats. Behav Neurosci 104:716-724, 1990
57. Forster MJ, Lal H: Autoimmunity and cognitive decline in aging and Alzheimer's disease. In Ader R, Felten DL, Cohen N (eds), Psychoneuroimmunology, 2nd Ed. New York, Academic Press, 1991, 709-748
58. Ader R, Cohen N: Psychoneuroimmunology: Conditioning and stress. Ann Rev Psychol 44:53-85, 1993
59. Ader R, Cohen N: Behaviorally conditioned immunosuppression and murine systemic lupus erythematosus. Science 215:1534-1536, 1982
60. Ader R: Psychoneuroimmunologic contributions to the study of rheumatic diseases. In Gupta S, Jalal N (eds), Immunology of Rheumatic Diseases. New York, Plenum, 1985, 669-696
61. Ader R, Grota LJ, Moynihan JA, et al: Behavioral adaptations in autoimmune disease-susceptible mice. In Ader R, Felten DL, Cohen N (eds), Psychoneuroimmunology, 2nd Ed. New York, Academic Press, 1991, 685-708
62. Surwit RS, Schneider MS, Feinglos MN: Stress and diabetes mellitus. Diabetes Care 15:1413-1422, 1992
63. Surwit RS, Schneider MS: The role of stress in the etiology ans treatment of diabetes mellitus. Psychosom Med 55:380-393, 1993
64. Karam JH, Salber PR, Forsham PH: Pancreatic hormones and diabetes mellitus. In Greenspan FS (ed), Basic and Clinical Endocrinology. Norwalk, CT, Appleton and Lange, 1991, 592:650
65. Carter WR, Herrman J, Stokes K, et al: Promotion of diabetes onset by stress in the BB rat. Diabetologia 30:674-675, 1987
66. Lehman CD, Rodin J, McEwen B, et al: Impact of environmental stress on the expression of insulin-dependent diabetes mellitus. Behav Neurosci 105:241-245, 1991
67. Durant S, Couland J, Amrani A, et al: Effects of various environmental stress paradigms and adrenalectomy on the expression of autoimmune Type 1 diabetes in the non-obese diabetic (NOD) mouse. J Autoimmun 6:735-751, 1993
68. Ader DN, Bennett Johnson S, Wen Huang S, et al: Group size, cage shelf level, and emotionality in nonobese diabetic mice: Impact on onset and incidence of IDDM. Psychosom Med 53:313-321, 1991
69. Sheridan JF, Dobbs C, Brown D, et al: Psychoneuroimniunology: stress effects on pathogenesis and immunity during infection. Clin Micro Rev 7:200-212, 1994
70. Yamada A, Jensen MM, Rasmussen AF: Stress and susceptibility to viral infections. III. Antobody response and viral retention during avoidance learning stress. Proc Soc Exp Biol Med 116:677-680 1964
71. Chang S, Rasmussen AF: Stress-induced suppression of Interferon production in virus-infected mice. Nature 205: 623-624, 1965
72. Wistar R, Hildemann WH: Effects of stress on skin transplantation immunity in mice. Science 131:159-160, 1960
73. Friedman SB, Ader R, Glasgow LA: Effect of psychological stress in adult mice inoculated with Coxsackie B viruses. Psychosom Med 27:361-368, 1965
74. Gatmaitan BG, Chason JL, Lermer AM: Augmentation of the virulence of murine coxsackie-virus B-3 myocardiopathy by exercise. J Exp Med 131:1121-1125, 1970
75. Reyes MP, Lerner AM: Interferon and neutralizing antibody in sera of exercised mice with coxsackie virus B-3 myocarditis. Proc Soc Exp Biol Med 151:333-338, 1976
76. Edwards EA, Dean LM: Effects of crowding of mice on humoral antibody formation and protection to lethal antigenie challenge. Psychosom Med 39:19-24, 1977
77. Rabin BS, Salvin SB: Effect of differential housing and time on immune reactivity to sheep erythrocytes and Candida. Brain Behav Immun 1:267-275, 1987
78. Rabin BS, Lyte M, Epstein LH, et al: Alteration of immune competency by number of mice housed per cage. Ann NY Acad Sci 496:492-500, 1987
79. Brown DH, Sheridan J, Pearl D, et al: Regulation of mycobacterial growth by the hypothalamus-pituitary-adrenal axis: Differential responses of Mycobacterium bovis BCG-resistant and -susceptible mice. Infect Immun 61:4793-4800, 1993
80. Zwilling BS, Brown D, Christner R, et al: Differential effect of restraint stress on MHC class II expression by peritoneal macrophages. Brain Behav Immun 4:330-338, 1990
81. Brown DH, Zwilling BS: Activation of the hypothalamicpituitary-adrenal axis differentially affects the antimycobac-terial activity of macrophages from BCG-resistant and sus-ceptible mice. J Neuroimmunol 53:181-187, 1994
82. Chetverikova LK, Frolov BA, Kramskaya TA, et al: Experimental influenza infection: influence of stress. Acta Virol 31:424-433, 1987
83. Sheridan JF, Feng N, Bonneau RH, et al: Restraint stress differentially affects antiviral cellular and humoral immune responses in mice. J Neuroimmunol 31:245-255, 1991
84. Hermann G, Tovar CA, Beck FM, et al: Restraint stress differentially affects the pathogenesis of an experimental influenza viral infection in three inbred strains of mice. J Neuroimmunol 47:83-93, 1993
85. Bonneau RH, Sheridan JF, Feng N, et al: Stress-induced suppression of herpes simplex virus (HSV)-specific cytotoxic T lymphocyte and natural killer cell activity and enhancement of acute pathogenesis following local HSV infection. Brain Behav Immun 5:170-102, 1991a
86. Bonneau RH, Sheridan JF, Feng N, et al: Stress-induced effects on cell-mediated innate and adaptive memory components of the murine immune response to herpes simplex virus. Brain Behav Immun 5:274-295, 1991b
87. Dobbs CM, Vasquez M, Glaser R, Sheridan JF: Mechanisms of stress-induced modulation of viral pathogenesis and immunity. J Neuroimmunol 48:151-160, 1993
88. Kusnecov AV, Grota LJ, Schmidt SG, et al: Decreased herpes simplex viral immunity and enhanced pathogenesis following stressor administration in mice. J Neuroimmunol 38: 129-138, 1992
89. Kemeny ME: Psychoneuroimunology of HIV infection. Psychol Clin North Am 17:55-68, 1994
90. Persson L, Gullberg B, Hanson BS, et al: HIV infection-social network, social support, and CD4 lymphocyte valiues in infected homosexual men in Malmo, Sweden. J Epidemiol Community Health 48:580-585, 1994
91. Montagne G, Lalonde R, Brouillette MJ: Psychoimmunology and AIDS - A review of the literature. Can J Psychiatry 39:404-409, 1994
92. Clerici M, Shearer GM: The Th1-Th2 hypothesis of HIV infection: New insights. Immunol Today 15:575-581, 1994
93. Salk J, Brotscher PA, Salk PL, et al: A strategy for prophylactic vaccination against HIV. Science 260:1270-1272, 1993
94. Shearer GM, Clerici M: T helper cell immune dysfunction in asymptomatic, HIV-1 seropositive individuals: The role of TH1-TH2 cross-regulation. In Coffman RL (ed), Chemical Immunology, vol 54: Regulation and Functional Significance of T-Cell Subsets. New York, Karger, 1992, 21-43
95. Cocke R, Moynihan JA, Cohen N, et al: Exposure to conspecific alarm chemosignals alters immune responses in BALB/c mice. Brain Behav Immun 4:36-46, 1993
96. Moynihan JA, Karp JD, Cohen N, et al: Differential effects of stress pheromones on cytokine production and immunity: possible role of glucocorticoids. J Neuroimmunol 54:51-58, 1994
97. Karp JD, Cohen N, Moynihan J: Effects of differential housing on cytokine production. Life Sci 55:789-795, 1994
98. Gazzanelli RT, Makino M, Chattopadhyay SK, et al: CD4+ subset regulation in viral infection: preferential activation of TH2 cells during progression of retrovirus-induced immunodeficiency in mice. J Immunol 148:182-186, 1992
99. Sher A, Gazzinelli RT, Oswald IP, et al: Role of T cell-derived cytokines in the downregulation of immune responses in parasitic and retroviral infections. Immunol Rev 127:183-204, 1992
100. Kanagawa O, Vaupel BA, Gayama S, et al: Resistance of mice deficient in IL-4 to retrovirus-induced immunodeficiency syndrome (MAIDS). Science 262:240-242, 1993
101. Solnick JV, Tompkins LS: Helicobacter pylori and gastroduodenal disease: Pathogenesis and host-parasite interaction. Infect Agents Dis 1:294-309, 1993
102. Marchetti M, Arico B, Burroni D, et al: Development of a mouse model of Helicobacter pylori infection that mimics human disease. Science 267:1655-1658, 1995
103. Riley V: Mouse mammary tumors: Alteration of incidence as apparent function of stress. Science 189:465-467, 1975
104. Perissin L, Zorzet S, Rapozzi V, et al: Seasonal dependency of the effects of experimental stressors on tumor metastasis in mice bearing Lewis lung carcinoma. Chronobiologia 21: 99-103, 1994
105. Sklar LS, Anisman H: Stress and cancer. Psychol Bull 89:369-406, 1981
106. Ben-Eliyahu S, Yirmiya R, Liebeskind JC, et al: Stress increases metastatic spread of a mammary tumor in rats: Evidence for mediation by the immune system. Brain Behav Immun 5:193-205, 1991
107. Page GG, Ben-Eliyahu S, Yirmiya R, et al: Morphine attenuates surgery-induced enhancement of metastatic colonization in rats. Pain 54:21-28, 1993
108. Brenner GJ, Cohen N, Ader R, et al: Increased pulmonary metastases in mice following handling. Life Sci 47:1813-1819, 1990
109. Kaplan JR, Pettersson K, Manuck SB, et al: Role of sympathoadrenal medullary activation in the initiation and progression of atherosclerosis. Circulation 84(suppl VI):23-32, 1991
110. Wick G, Schett G, Amberger A, et al: Is atherosclerosis an immunologically mediated disease? Immunol Today 16:27-33, 1995
111. Speir E, Modali R, Huang E-S, et al: Potential role of human cytomegalovirus and p53 interaction in coronary restenosis. Science 265:391-393, 1994
112. Grochowicz PM, Schedlowski M, Husband AJ, et al: Behavioral conditioning prolongs heart allograft survival in rats. Brain Behav Immun 5:349-356, 1991
113. Gorczynski RM: Conditioned enhancement of skin allograft enhancement in mice. Brain Behav Immun 4:85-92, 1990
114. Olness K, Ader R: Conditioning as an adjunct in the pharmacotherapy of lupus erythematosus: A case report. J Dev Behav Pediatr 13:124-125, 1992